Homo sapiens

52 known processes

SRSF4

serine/arginine-rich splicing factor 4

(Aliases: SFRS4,SRP75)

SRSF4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of epidermis development GO:0045683 5 0.991
Human
regulation of epithelial cell proliferation involved in lung morphogenesis GO:2000794 2 0.942
Human
regulation of meiotic cell cycle GO:0051445 4 0.896
negative regulation of epidermal cell differentiation GO:0045605 4 0.878
Human
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 2 0.813
Human
female sex determination GO:0030237 1 0.780
lung morphogenesis GO:0060425 6 0.774
Human
lung epithelium development GO:0060428 7 0.629
Human
mrna splicing via spliceosome GO:0000398 89 0.530
mrna processing GO:0006397 133 0.519
regulation of meiosis GO:0040020 3 0.466
mrna splice site selection GO:0006376 7 0.457
Human
ribonucleoprotein complex biogenesis GO:0022613 116 0.442
Human
mrna metabolic process GO:0016071 175 0.407
regulation of mrna splicing via spliceosome GO:0048024 32 0.312
sex determination GO:0007530 3 0.305
regulation of mrna metabolic process GO:1903311 53 0.247
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.224
lung development GO:0030324 20 0.222
Human
rna splicing GO:0008380 131 0.216
nuclear division GO:0000280 128 0.214
Fly
epidermal cell differentiation GO:0009913 45 0.213
Human
cell division GO:0051301 168 0.172
positive regulation of epithelial cell proliferation GO:0050679 65 0.169
Human
keratinocyte proliferation GO:0043616 17 0.167
Human
regulation of response to wounding GO:1903034 101 0.166
Human
respiratory system development GO:0060541 22 0.165
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.165
keratinocyte differentiation GO:0030216 36 0.156
Human
post embryonic development GO:0009791 2 0.149
Worm
respiratory tube development GO:0030323 20 0.146
Human
regulation of wound healing GO:0061041 56 0.131
Human
positive regulation of developmental process GO:0051094 314 0.125
Human Worm
negative regulation of epithelial cell differentiation GO:0030857 6 0.124
Human
ribonucleoprotein complex assembly GO:0022618 78 0.123
Human
negative regulation of rna splicing GO:0033119 15 0.123
regulation of cell cycle process GO:0010564 266 0.106
epithelial cell differentiation GO:0030855 141 0.105
Human
regulation of mrna processing GO:0050684 48 0.094
wound healing GO:0042060 115 0.091
Human
regulation of epithelial cell proliferation GO:0050678 113 0.091
Human
regulation of epithelial cell differentiation GO:0030856 24 0.090
Human
regulation of mapk cascade GO:0043408 262 0.089
regulation of cell cycle GO:0051726 393 0.088
skin development GO:0043588 76 0.081
Human
mrna 5 splice site recognition GO:0000395 3 0.079
spliceosomal complex assembly GO:0000245 17 0.077
Human
negative regulation of cell death GO:0060548 345 0.076
Human
regulation of keratinocyte differentiation GO:0045616 11 0.075
Human
covalent chromatin modification GO:0016569 254 0.069
response to wounding GO:0009611 168 0.066
Human
regulation of cell differentiation GO:0045595 393 0.065
Human
segmentation GO:0035282 4 0.062
tube development GO:0035295 125 0.062
Human
negative regulation of multicellular organismal process GO:0051241 317 0.062
Human
cellular macromolecular complex assembly GO:0034622 324 0.061
Human
blood vessel development GO:0001568 172 0.057
multicellular organismal aging GO:0010259 3 0.054
protein ubiquitination GO:0016567 314 0.053
ribonucleoprotein complex subunit organization GO:0071826 81 0.052
Human
signal transduction by phosphorylation GO:0023014 297 0.052
nuclear transcribed mrna catabolic process GO:0000956 48 0.051
epithelial cell proliferation GO:0050673 128 0.051
Human
epithelium development GO:0060429 227 0.050
Human
mapk cascade GO:0000165 288 0.050
regulation of nuclear division GO:0051783 65 0.049
regulation of anatomical structure morphogenesis GO:0022603 286 0.049
Human
gonad development GO:0008406 34 0.048
Worm
regulation of organ morphogenesis GO:2000027 24 0.048
Human
determination of adult lifespan GO:0008340 2 0.046
reproductive process GO:0022414 106 0.046
Worm
cellular component disassembly GO:0022411 92 0.045
cell activation GO:0001775 213 0.044
nucleus localization GO:0051647 1 0.044
cellular amino acid metabolic process GO:0006520 116 0.043
sex differentiation GO:0007548 45 0.041
Worm
positive regulation of phosphorylation GO:0042327 394 0.040
negative regulation of protein metabolic process GO:0051248 391 0.038
cell development GO:0048468 328 0.037
ras protein signal transduction GO:0007265 73 0.037
female gamete generation GO:0007292 2 0.036
negative regulation of mrna processing GO:0050686 12 0.036
negative regulation of cell differentiation GO:0045596 171 0.035
Human
phagocytosis recognition GO:0006910 3 0.035
negative regulation of mrna metabolic process GO:1903312 15 0.035
alternative mrna splicing via spliceosome GO:0000380 27 0.034
Human Fly
rna splicing via transesterification reactions GO:0000375 90 0.033
vasculature development GO:0001944 181 0.033
amine metabolic process GO:0009308 44 0.033
positive regulation of mapk cascade GO:0043410 190 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
maintenance of location GO:0051235 112 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
embryo development GO:0009790 123 0.030
Worm
defense response GO:0006952 315 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.028
rna processing GO:0006396 255 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.027
lymphocyte activation GO:0046649 133 0.026
blood vessel morphogenesis GO:0048514 162 0.026
somatic stem cell maintenance GO:0035019 4 0.025
regulation of rna splicing GO:0043484 62 0.025
cellular amine metabolic process GO:0044106 41 0.025
leukocyte differentiation GO:0002521 98 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
intracellular mrna localization GO:0008298 1 0.023
defense response to fungus GO:0050832 4 0.023
leukocyte activation GO:0045321 164 0.022
sulfur compound biosynthetic process GO:0044272 38 0.022
cofactor metabolic process GO:0051186 87 0.021
cellular ketone metabolic process GO:0042180 80 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
chemical homeostasis GO:0048878 306 0.021
organelle fission GO:0048285 149 0.021
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
regulation of erk1 and erk2 cascade GO:0070372 99 0.020
response to external biotic stimulus GO:0043207 261 0.020
peripheral nervous system development GO:0007422 2 0.020
regulation of protein transport GO:0051223 213 0.020
response to lipid GO:0033993 206 0.020
locomotory behavior GO:0007626 1 0.020
oxidation reduction process GO:0055114 396 0.020
histone deacetylation GO:0016575 32 0.019
regulation of cell activation GO:0050865 125 0.019
response to other organism GO:0051707 261 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.019
cellular cation homeostasis GO:0030003 163 0.019
protein deubiquitination GO:0016579 79 0.019
cellular macromolecule catabolic process GO:0044265 380 0.018
regulation of protein stability GO:0031647 87 0.018
spermatid development GO:0007286 4 0.018
meiotic chromosome segregation GO:0045132 4 0.018
regulation of protein maturation GO:1903317 150 0.018
regulation of immune response GO:0050776 201 0.018
regulation of protein ubiquitination GO:0031396 95 0.018
regulation of leukocyte activation GO:0002694 115 0.018
positive regulation of immune system process GO:0002684 283 0.017
hemopoiesis GO:0030097 180 0.017
Mouse
cytokine production GO:0001816 247 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.017
immune effector process GO:0002252 159 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.017
regulation of protein processing GO:0070613 150 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
response to oxygen containing compound GO:1901700 369 0.017
regulation of gene expression epigenetic GO:0040029 73 0.017
compound eye development GO:0048749 1 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
rna interference GO:0016246 4 0.017
positive regulation of cell death GO:0010942 263 0.017
nuclear migration GO:0007097 1 0.017
cell adhesion GO:0007155 325 0.016
interspecies interaction between organisms GO:0044419 156 0.016
regulation of lymphocyte activation GO:0051249 103 0.016
histone modification GO:0016570 251 0.016
small molecule biosynthetic process GO:0044283 157 0.016
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.016
Human
regulation of cell division GO:0051302 116 0.016
tripartite regional subdivision GO:0007351 2 0.016
metal ion transport GO:0030001 272 0.016
apoptotic signaling pathway GO:0097190 268 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
response to fungus GO:0009620 4 0.016
response to biotic stimulus GO:0009607 276 0.016
angiogenesis GO:0001525 147 0.015
cation transport GO:0006812 331 0.015
spermatid differentiation GO:0048515 4 0.015
nervous system development GO:0007399 293 0.015
mitotic nuclear division GO:0007067 119 0.015
Fly
negative regulation of phosphorylation GO:0042326 174 0.015
intracellular protein transport GO:0006886 270 0.015
viral life cycle GO:0019058 132 0.015
sulfur amino acid metabolic process GO:0000096 14 0.015
t cell differentiation in thymus GO:0033077 4 0.015
behavioral response to ethanol GO:0048149 2 0.015
anterior posterior axis specification GO:0009948 2 0.014
histone methylation GO:0016571 60 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
blastoderm segmentation GO:0007350 2 0.014
ion homeostasis GO:0050801 230 0.014
negative regulation of protein modification process GO:0031400 200 0.014
behavior GO:0007610 112 0.014
t cell activation GO:0042110 99 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
Human
multicellular organism reproduction GO:0032504 42 0.014
Worm
positive regulation of mrna metabolic process GO:1903313 19 0.014
system process GO:0003008 349 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
regulation of viral genome replication GO:0045069 48 0.013
regulation of secretion GO:0051046 194 0.013
single organism reproductive process GO:0044702 98 0.013
Worm
regulation of histone h3 k27 methylation GO:0061085 4 0.013
myeloid cell differentiation GO:0030099 117 0.013
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.013
protein targeting GO:0006605 187 0.013
cellular response to organic cyclic compound GO:0071407 127 0.013
negative regulation of developmental process GO:0051093 247 0.013
Human
cellular ion homeostasis GO:0006873 168 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
somitogenesis GO:0001756 2 0.013
cell projection organization GO:0030030 252 0.013
cell fate determination GO:0001709 3 0.013
positive regulation of meiotic cell cycle GO:0051446 2 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
regulation of cell motility GO:2000145 299 0.013
mating GO:0007618 1 0.013
regulation of transferase activity GO:0051338 355 0.013
thymus development GO:0048538 3 0.013
actin filament based process GO:0030029 224 0.012
rhythmic behavior GO:0007622 2 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
vesicle mediated transport GO:0016192 371 0.012
biological adhesion GO:0022610 331 0.012
establishment of nucleus localization GO:0040023 1 0.012
multi organism cellular process GO:0044764 156 0.012
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.012
protein localization to organelle GO:0033365 280 0.012
neuromuscular junction development GO:0007528 3 0.012
protein modification by small protein removal GO:0070646 92 0.012
meiotic nuclear division GO:0007126 10 0.012
negative regulation of endopeptidase activity GO:0010951 84 0.012
response to abiotic stimulus GO:0009628 336 0.012
cellular response to lipid GO:0071396 127 0.011
reproduction GO:0000003 63 0.011
Worm
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
positive regulation of b cell mediated immunity GO:0002714 4 0.011
cardiovascular system development GO:0072358 262 0.011
lipid metabolic process GO:0006629 381 0.011
epithelium migration GO:0090132 119 0.011
male meiosis GO:0007140 1 0.011
regulation of oocyte development GO:0060281 1 0.011
regulation of cell growth GO:0001558 135 0.011
defense response to other organism GO:0098542 129 0.011
glial cell migration GO:0008347 4 0.011
circulatory system development GO:0072359 262 0.011
generation of neurons GO:0048699 152 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
mitotic cell cycle process GO:1903047 286 0.011
Fly
reactive oxygen species metabolic process GO:0072593 75 0.011
protein dephosphorylation GO:0006470 81 0.011
negative regulation of viral genome replication GO:0045071 35 0.011
regulation of cellular response to stress GO:0080135 244 0.011
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.011
embryo development ending in birth or egg hatching GO:0009792 34 0.011
Worm
mrna cis splicing via spliceosome GO:0045292 7 0.011
negative regulation of protein maturation GO:1903318 142 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
cellular modified amino acid metabolic process GO:0006575 64 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
circadian behavior GO:0048512 2 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
cation homeostasis GO:0055080 189 0.010
generation of precursor metabolites and energy GO:0006091 68 0.010
protein peptidyl prolyl isomerization GO:0000413 8 0.010
cellular potassium ion transport GO:0071804 60 0.010
regulation of viral process GO:0050792 103 0.010
cellular homeostasis GO:0019725 196 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
negative regulation of mapk cascade GO:0043409 56 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
positive regulation of transferase activity GO:0051347 227 0.010
carbohydrate metabolic process GO:0005975 207 0.010
microtubule based process GO:0007017 210 0.010
epithelial cell migration GO:0010631 119 0.010
regulation of synaptic plasticity GO:0048167 3 0.010

SRSF4 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.058
neurodegenerative disease DOID:1289 102 0.058
nervous system disease DOID:863 431 0.058
musculoskeletal system disease DOID:17 223 0.036
muscular disease DOID:0080000 114 0.031
disease of metabolism DOID:0014667 295 0.015
inherited metabolic disorder DOID:655 242 0.015
myopathy DOID:423 104 0.014
muscle tissue disease DOID:66 113 0.014
tauopathy DOID:680 16 0.012
disease of mental health DOID:150 70 0.011
cognitive disorder DOID:1561 29 0.011