Homo sapiens

97 known processes

PDE3A

phosphodiesterase 3A, cGMP-inhibited

(Aliases: CGI-PDE)

PDE3A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.193
amine metabolic process GO:0009308 44 0.174
cellular amino acid metabolic process GO:0006520 116 0.168
regulation of cellular amine metabolic process GO:0033238 11 0.167
regulation of cellular ketone metabolic process GO:0010565 50 0.166
cellular ketone metabolic process GO:0042180 80 0.148
positive regulation of cellular amine metabolic process GO:0033240 7 0.137
regulation of cellular amino acid metabolic process GO:0006521 6 0.135
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.134
system process GO:0003008 349 0.114
transmembrane transport GO:0055085 399 0.101
regulation of cellular component movement GO:0051270 334 0.098
cation transport GO:0006812 331 0.098
positive regulation of protein phosphorylation GO:0001934 313 0.095
positive regulation of transport GO:0051050 336 0.094
g protein coupled receptor signaling pathway GO:0007186 207 0.093
response to oxygen containing compound GO:1901700 369 0.090
metal ion transport GO:0030001 272 0.090
chemical homeostasis GO:0048878 306 0.089
regulation of locomotion GO:0040012 329 0.089
positive regulation of phosphorylation GO:0042327 394 0.087
purine nucleotide catabolic process GO:0006195 405 0.086
small gtpase mediated signal transduction GO:0007264 78 0.086
purine ribonucleotide catabolic process GO:0009154 404 0.085
ion homeostasis GO:0050801 230 0.083
cellular response to endogenous stimulus GO:0071495 336 0.081
purine containing compound catabolic process GO:0072523 411 0.080
post embryonic development GO:0009791 2 0.079
circulatory system development GO:0072359 262 0.079
Human
regulation of cell migration GO:0030334 289 0.078
cardiovascular system development GO:0072358 262 0.077
Human
ion transmembrane transport GO:0034220 338 0.076
cellular homeostasis GO:0019725 196 0.074
positive regulation of developmental process GO:0051094 314 0.073
Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.073
ras protein signal transduction GO:0007265 73 0.072
ribonucleotide catabolic process GO:0009261 405 0.071
regulation of cell motility GO:2000145 299 0.069
cell development GO:0048468 328 0.069
Mouse Rat
organophosphate catabolic process GO:0046434 430 0.068
positive regulation of hydrolase activity GO:0051345 331 0.067
metal ion homeostasis GO:0055065 169 0.067
negative regulation of multicellular organismal process GO:0051241 317 0.067
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.066
regulation of cell differentiation GO:0045595 393 0.065
Mouse
regulation of mapk cascade GO:0043408 262 0.064
regulation of nucleotide metabolic process GO:0006140 269 0.064
secretion GO:0046903 254 0.064
cyclic nucleotide metabolic process GO:0009187 82 0.064
cation homeostasis GO:0055080 189 0.064
cell adhesion GO:0007155 325 0.063
Human
purine ribonucleoside metabolic process GO:0046128 437 0.063
response to growth factor GO:0070848 205 0.063
regulation of transferase activity GO:0051338 355 0.062
nervous system development GO:0007399 293 0.062
regulation of purine nucleotide metabolic process GO:1900542 264 0.062
nucleoside triphosphate metabolic process GO:0009141 422 0.061
mapk cascade GO:0000165 288 0.061
cellular metal ion homeostasis GO:0006875 146 0.061
positive regulation of cell proliferation GO:0008284 301 0.060
regulation of secretion GO:0051046 194 0.059
signal transduction by phosphorylation GO:0023014 297 0.059
lipid metabolic process GO:0006629 381 0.059
Human Rat
blood vessel development GO:0001568 172 0.059
Human
cellular response to oxygen containing compound GO:1901701 276 0.059
purine nucleoside triphosphate catabolic process GO:0009146 392 0.058
cellular chemical homeostasis GO:0055082 180 0.058
regulation of kinase activity GO:0043549 314 0.058
nucleoside triphosphate catabolic process GO:0009143 394 0.058
carbohydrate derivative biosynthetic process GO:1901137 207 0.058
biological adhesion GO:0022610 331 0.057
Human
cytokine production GO:0001816 247 0.057
positive regulation of cellular component organization GO:0051130 376 0.057
cation transmembrane transport GO:0098655 238 0.056
nucleotide catabolic process GO:0009166 408 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.056
blood vessel morphogenesis GO:0048514 162 0.055
Human
glycosyl compound catabolic process GO:1901658 413 0.055
positive regulation of nucleotide metabolic process GO:0045981 230 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.055
actin filament based process GO:0030029 224 0.054
organonitrogen compound biosynthetic process GO:1901566 200 0.054
muscle contraction GO:0006936 73 0.053
single organism cellular localization GO:1902580 332 0.053
negative regulation of protein metabolic process GO:0051248 391 0.053
positive regulation of protein kinase activity GO:0045860 190 0.053
negative regulation of cell proliferation GO:0008285 228 0.052
defense response GO:0006952 315 0.052
nucleoside catabolic process GO:0009164 408 0.052
purine ribonucleoside catabolic process GO:0046130 398 0.052
ribonucleoside triphosphate metabolic process GO:0009199 412 0.052
positive regulation of catabolic process GO:0009896 310 0.052
cell morphogenesis GO:0000902 296 0.052
regulation of cytokine production GO:0001817 232 0.052
positive regulation of mapk cascade GO:0043410 190 0.051
vasculature development GO:0001944 181 0.051
Human
purine nucleoside catabolic process GO:0006152 398 0.051
locomotory behavior GO:0007626 1 0.051
anatomical structure formation involved in morphogenesis GO:0048646 284 0.050
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.050
cgmp catabolic process GO:0046069 3 0.050
ribonucleoside catabolic process GO:0042454 406 0.050
response to organic cyclic compound GO:0014070 204 0.050
regulation of establishment of protein localization GO:0070201 242 0.050
female gamete generation GO:0007292 2 0.050
Mouse Rat
regulation of protein kinase activity GO:0045859 289 0.050
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.049
purine nucleoside triphosphate metabolic process GO:0009144 412 0.049
cellular divalent inorganic cation homeostasis GO:0072503 128 0.049
inorganic ion transmembrane transport GO:0098660 231 0.049
secretion by cell GO:0032940 226 0.049
cytoplasmic transport GO:0016482 379 0.048
guanosine containing compound metabolic process GO:1901068 244 0.048
blood circulation GO:0008015 113 0.048
negative regulation of cell death GO:0060548 345 0.047
Rat
cellular ion homeostasis GO:0006873 168 0.047
cellular cation homeostasis GO:0030003 163 0.047
regulation of secretion by cell GO:1903530 177 0.047
regulation of cellular component biogenesis GO:0044087 281 0.047
single organism membrane organization GO:0044802 268 0.046
oogenesis GO:0048477 2 0.046
Mouse Rat
calcium ion homeostasis GO:0055074 122 0.046
immune response GO:0006955 307 0.046
regulation of ion transport GO:0043269 189 0.045
regulation of protein localization GO:0032880 296 0.045
regulation of cell adhesion GO:0030155 166 0.045
Human
response to abiotic stimulus GO:0009628 336 0.045
inorganic cation transmembrane transport GO:0098662 194 0.045
cell projection organization GO:0030030 252 0.045
rho protein signal transduction GO:0007266 26 0.044
multicellular organismal aging GO:0010259 3 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.044
positive regulation of cell motility GO:2000147 177 0.044
cellular component morphogenesis GO:0032989 314 0.043
divalent inorganic cation homeostasis GO:0072507 136 0.043
determination of adult lifespan GO:0008340 2 0.043
organophosphate biosynthetic process GO:0090407 163 0.043
negative regulation of phosphate metabolic process GO:0045936 267 0.043
vesicle mediated transport GO:0016192 371 0.043
muscle system process GO:0003012 81 0.043
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
calcium ion transport GO:0006816 147 0.042
negative regulation of catalytic activity GO:0043086 335 0.042
segmentation GO:0035282 4 0.042
gtp catabolic process GO:0006184 237 0.042
membrane organization GO:0061024 292 0.042
positive regulation of cellular catabolic process GO:0031331 284 0.042
regulation of protein transport GO:0051223 213 0.041
positive regulation of transferase activity GO:0051347 227 0.041
divalent metal ion transport GO:0070838 152 0.041
regulation of anatomical structure morphogenesis GO:0022603 286 0.041
Human
circulatory system process GO:0003013 113 0.040
guanosine containing compound catabolic process GO:1901069 239 0.040
peptidyl tyrosine phosphorylation GO:0018108 170 0.040
cytosolic calcium ion homeostasis GO:0051480 89 0.040
negative regulation of transport GO:0051051 176 0.039
positive regulation of locomotion GO:0040017 186 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
gtp metabolic process GO:0046039 239 0.038
positive regulation of cell differentiation GO:0045597 211 0.038
Mouse
angiogenesis GO:0001525 147 0.038
Human
neuron differentiation GO:0030182 138 0.038
positive regulation of kinase activity GO:0033674 204 0.037
memory GO:0007613 3 0.037
regulation of purine nucleotide catabolic process GO:0033121 205 0.037
single organism cell adhesion GO:0098602 179 0.036
regulation of intracellular transport GO:0032386 195 0.036
peptidyl tyrosine modification GO:0018212 170 0.036
positive regulation of gtpase activity GO:0043547 166 0.036
cellular calcium ion homeostasis GO:0006874 117 0.036
regulation of response to external stimulus GO:0032101 222 0.036
negative regulation of programmed cell death GO:0043069 321 0.036
Rat
response to organonitrogen compound GO:0010243 156 0.036
nucleoside phosphate biosynthetic process GO:1901293 109 0.035
neuromuscular junction development GO:0007528 3 0.035
response to lipid GO:0033993 206 0.035
response to biotic stimulus GO:0009607 276 0.035
regulation of nucleoside metabolic process GO:0009118 209 0.035
regulation of system process GO:0044057 101 0.035
positive regulation of cytokine production GO:0001819 167 0.035
maintenance of location GO:0051235 112 0.035
purine ribonucleotide biosynthetic process GO:0009152 79 0.034
divalent inorganic cation transport GO:0072511 158 0.034
cellular response to growth factor stimulus GO:0071363 197 0.034
carbohydrate metabolic process GO:0005975 207 0.034
taxis GO:0042330 157 0.034
cellular lipid metabolic process GO:0044255 303 0.033
Rat
motor neuron axon guidance GO:0008045 2 0.033
positive regulation of nucleotide catabolic process GO:0030813 185 0.033
regulation of hormone levels GO:0010817 125 0.033
regulation of gtpase activity GO:0043087 180 0.033
positive regulation of nucleoside metabolic process GO:0045979 186 0.033
intracellular protein transport GO:0006886 270 0.033
negative regulation of apoptotic process GO:0043066 316 0.033
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.033
regulation of cell cycle GO:0051726 393 0.033
Mouse
neurological system process GO:0050877 163 0.033
response to nitrogen compound GO:1901698 184 0.032
blastoderm segmentation GO:0007350 2 0.032
cell cell signaling GO:0007267 155 0.032
regulation of gtp catabolic process GO:0033124 180 0.032
growth GO:0040007 202 0.032
positive regulation of immune system process GO:0002684 283 0.032
actin cytoskeleton organization GO:0030036 207 0.032
hindbrain development GO:0030902 3 0.032
nitrogen compound transport GO:0071705 191 0.032
cardiac muscle cell contraction GO:0086003 4 0.032
positive regulation of cellular component movement GO:0051272 181 0.032
neurogenesis GO:0022008 169 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.032
response to cytokine GO:0034097 232 0.032
cellular response to organic cyclic compound GO:0071407 127 0.031
epithelium development GO:0060429 227 0.031
response to external biotic stimulus GO:0043207 261 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.031
camp metabolic process GO:0046058 61 0.031
cell substrate adhesion GO:0031589 132 0.031
lipid biosynthetic process GO:0008610 177 0.031
ameboidal type cell migration GO:0001667 135 0.030
single organismal cell cell adhesion GO:0016337 148 0.030
apoptotic signaling pathway GO:0097190 268 0.030
single organism carbohydrate metabolic process GO:0044723 193 0.030
regeneration GO:0031099 4 0.030
nucleotide biosynthetic process GO:0009165 109 0.030
regulation of protein serine threonine kinase activity GO:0071900 179 0.029
negative regulation of developmental process GO:0051093 247 0.029
Human
positive regulation of gtp catabolic process GO:0033126 166 0.029
response to wounding GO:0009611 168 0.029
protein localization to organelle GO:0033365 280 0.029
response to hormone GO:0009725 175 0.029
chemotaxis GO:0006935 157 0.029
regulation of small gtpase mediated signal transduction GO:0051056 156 0.029
regulation of cytoplasmic transport GO:1903649 149 0.029
regulation of proteolysis GO:0030162 293 0.029
response to other organism GO:0051707 261 0.029
organ morphogenesis GO:0009887 147 0.029
hematopoietic or lymphoid organ development GO:0048534 186 0.028
immune system development GO:0002520 195 0.028
generation of neurons GO:0048699 152 0.028
second messenger mediated signaling GO:0019932 78 0.028
positive regulation of cell migration GO:0030335 172 0.028
hemopoiesis GO:0030097 180 0.028
positive regulation of synaptic transmission GO:0050806 4 0.028
activation of protein kinase activity GO:0032147 90 0.028
negative regulation of cell migration GO:0030336 102 0.028
protein catabolic process GO:0030163 325 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
ribonucleotide biosynthetic process GO:0009260 81 0.028
regulation of ras protein signal transduction GO:0046578 155 0.028
regulation of actin filament based process GO:0032970 141 0.028
cell activation GO:0001775 213 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.028
regulation of metal ion transport GO:0010959 120 0.027
negative regulation of locomotion GO:0040013 118 0.027
regulation of ion transmembrane transport GO:0034765 132 0.027
cellular response to nitrogen compound GO:1901699 144 0.027
protein maturation GO:0051604 233 0.027
neuron projection development GO:0031175 106 0.027
mitotic cell cycle GO:0000278 326 0.026
ribose phosphate biosynthetic process GO:0046390 82 0.026
positive regulation of secretion by cell GO:1903532 108 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
tissue migration GO:0090130 119 0.026
dephosphorylation GO:0016311 209 0.026
sequestering of metal ion GO:0051238 24 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
actin mediated cell contraction GO:0070252 12 0.026
small molecule biosynthetic process GO:0044283 157 0.026
regulation of transmembrane transport GO:0034762 139 0.026
anterior posterior axis specification GO:0009948 2 0.025
protein processing GO:0016485 226 0.025
negative regulation of protein modification process GO:0031400 200 0.025
positive regulation of cell death GO:0010942 263 0.025
negative regulation of cellular component movement GO:0051271 106 0.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.025
purine nucleotide biosynthetic process GO:0006164 84 0.025
mitotic cell cycle process GO:1903047 286 0.025
epithelium migration GO:0090132 119 0.024
regulation of growth GO:0040008 165 0.024
organ formation GO:0048645 3 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
positive regulation of protein transport GO:0051222 135 0.024
regulation of cell development GO:0060284 161 0.024
Mouse
negative regulation of phosphorylation GO:0042326 174 0.024
positive regulation of cell adhesion GO:0045785 84 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.024
sequestering of calcium ion GO:0051208 17 0.024
cell fate determination GO:0001709 3 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.023
protein targeting GO:0006605 187 0.023
anion transport GO:0006820 161 0.023
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
actin filament based movement GO:0030048 17 0.023
regulation of cellular response to stress GO:0080135 244 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
protein localization to membrane GO:0072657 160 0.023
cyclic nucleotide biosynthetic process GO:0009190 61 0.023
camp biosynthetic process GO:0006171 47 0.023
oocyte development GO:0048599 1 0.023
Mouse Rat
positive regulation of map kinase activity GO:0043406 80 0.023
reactive nitrogen species metabolic process GO:2001057 3 0.023
nerve development GO:0021675 4 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
positive regulation of programmed cell death GO:0043068 249 0.023
cell growth GO:0016049 160 0.023
epithelial cell proliferation GO:0050673 128 0.023
endothelial cell migration GO:0043542 86 0.023
purine containing compound biosynthetic process GO:0072522 88 0.022
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.022
ossification GO:0001503 121 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
innate immune response GO:0045087 178 0.022
epithelial cell differentiation GO:0030855 141 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
sensory perception of smell GO:0007608 2 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
metencephalon development GO:0022037 2 0.022
regulation of map kinase activity GO:0043405 108 0.022
cell projection morphogenesis GO:0048858 129 0.022
epithelial cell migration GO:0010631 119 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.022
cyclic purine nucleotide metabolic process GO:0052652 60 0.022
reactive oxygen species biosynthetic process GO:1903409 4 0.022
regulation of cell cycle process GO:0010564 266 0.022
Mouse
nuclear transport GO:0051169 179 0.022
associative learning GO:0008306 1 0.022
mating GO:0007618 1 0.021
behavior GO:0007610 112 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
tube development GO:0035295 125 0.021
oocyte differentiation GO:0009994 2 0.021
Mouse Rat
regulation of transmembrane transporter activity GO:0022898 74 0.021
endomembrane system organization GO:0010256 196 0.021
myeloid cell differentiation GO:0030099 117 0.021
regulation of cell growth GO:0001558 135 0.021
peripheral nervous system development GO:0007422 2 0.021
positive regulation of organelle organization GO:0010638 195 0.021
regulation of membrane potential GO:0042391 95 0.021
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.021
rhythmic behavior GO:0007622 2 0.021
oxidation reduction process GO:0055114 396 0.021
protein modification by small protein conjugation GO:0032446 342 0.021
cell morphogenesis involved in differentiation GO:0000904 144 0.021
negative regulation of cell motility GO:2000146 104 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
protein oligomerization GO:0051259 173 0.021
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.021
negative regulation of synaptic transmission GO:0050805 2 0.021
cell part morphogenesis GO:0032990 137 0.021
tripartite regional subdivision GO:0007351 2 0.021
forebrain generation of neurons GO:0021872 3 0.020
regulation of camp metabolic process GO:0030814 52 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
lipid localization GO:0010876 106 0.020
cardiac muscle contraction GO:0060048 34 0.020
cellular response to organonitrogen compound GO:0071417 124 0.020
regulation of peptidase activity GO:0052547 180 0.020
regulation of blood circulation GO:1903522 59 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
monocarboxylic acid metabolic process GO:0032787 185 0.020
lung alveolus development GO:0048286 4 0.020
regulation of behavior GO:0050795 82 0.020
anterior posterior axis specification embryo GO:0008595 2 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
negative regulation of cell cycle GO:0045786 193 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
protein ubiquitination GO:0016567 314 0.020
head development GO:0060322 108 0.020
cerebellum development GO:0021549 2 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
chromatin organization GO:0006325 351 0.020
cranial nerve development GO:0021545 4 0.020
vasodilation GO:0042311 4 0.020
regulation of transporter activity GO:0032409 82 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
neuron development GO:0048666 113 0.020
adult locomotory behavior GO:0008344 1 0.020
monovalent inorganic cation transport GO:0015672 128 0.019
regulation of angiogenesis GO:0045765 92 0.019
Human
regulation of nucleotide biosynthetic process GO:0030808 50 0.019
positive regulation of secretion GO:0051047 116 0.019
response to axon injury GO:0048678 1 0.019
neurotransmitter secretion GO:0007269 4 0.019
positive regulation of cellular component biogenesis GO:0044089 158 0.019
central nervous system development GO:0007417 123 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.019
regulation of homeostatic process GO:0032844 121 0.019
multicellular organismal response to stress GO:0033555 1 0.019
regulation of response to wounding GO:1903034 101 0.019
cellular response to cytokine stimulus GO:0071345 181 0.019
lipid transport GO:0006869 90 0.019
regulation of calcium ion transport GO:0051924 79 0.019
immune effector process GO:0002252 159 0.019
limbic system development GO:0021761 3 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
cell division GO:0051301 168 0.019
Mouse
negative regulation of cell adhesion GO:0007162 64 0.019
Human
receptor metabolic process GO:0043112 81 0.019
glial cell migration GO:0008347 4 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
brain development GO:0007420 97 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.019
stem cell division GO:0017145 2 0.019
plasma membrane organization GO:0007009 115 0.019
inner ear morphogenesis GO:0042472 4 0.019
regulation of synaptic plasticity GO:0048167 3 0.019
nucleocytoplasmic transport GO:0006913 176 0.018
glycoprotein metabolic process GO:0009100 110 0.018
leukocyte activation GO:0045321 164 0.018
regulation of immune response GO:0050776 201 0.018
potassium ion transmembrane transport GO:0071805 60 0.018
compound eye development GO:0048749 1 0.018
interspecies interaction between organisms GO:0044419 156 0.018
endocytosis GO:0006897 159 0.018
regulation of mitotic cell cycle GO:0007346 189 0.018
cell matrix adhesion GO:0007160 85 0.018
cellular protein complex assembly GO:0043623 188 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
wnt signaling pathway GO:0016055 156 0.018
positive regulation of immune response GO:0050778 159 0.018
regulation of actin cytoskeleton organization GO:0032956 116 0.018
embryonic viscerocranium morphogenesis GO:0048703 1 0.018
spermatid differentiation GO:0048515 4 0.018
pituitary gland development GO:0021983 2 0.017
regulation of protein catabolic process GO:0042176 155 0.017
osteoblast differentiation GO:0001649 92 0.017
regulation of dna metabolic process GO:0051052 153 0.017
cellular protein catabolic process GO:0044257 261 0.017
cell chemotaxis GO:0060326 112 0.017
skeletal system development GO:0001501 79 0.017
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.017
regulation of ion homeostasis GO:2000021 73 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
wound healing GO:0042060 115 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
glycerolipid metabolic process GO:0046486 107 0.017
salivary gland morphogenesis GO:0007435 4 0.017
protein localization to plasma membrane GO:0072659 93 0.017
leukocyte migration GO:0050900 107 0.017
cellular potassium ion transport GO:0071804 60 0.017
positive regulation of cell development GO:0010720 92 0.017
Mouse
regulation of vasculature development GO:1901342 97 0.017
Human
positive regulation of camp biosynthetic process GO:0030819 35 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
activation of mapk activity GO:0000187 45 0.017
regulation of endothelial cell migration GO:0010594 67 0.017
regulation of camp biosynthetic process GO:0030817 45 0.017
muscle structure development GO:0061061 98 0.017
striated muscle contraction GO:0006941 52 0.017
cell type specific apoptotic process GO:0097285 125 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
histone modification GO:0016570 251 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
regulation of neurotransmitter secretion GO:0046928 3 0.017
circadian behavior GO:0048512 2 0.017
reproductive process GO:0022414 106 0.017
Mouse Rat
regulation of vesicle mediated transport GO:0060627 130 0.017
negative regulation of immune system process GO:0002683 136 0.017
regulation of ion transmembrane transporter activity GO:0032412 72 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
sensory perception of pain GO:0019233 4 0.016
cellular response to hormone stimulus GO:0032870 125 0.016
protein import GO:0017038 130 0.016
neuroblast proliferation GO:0007405 4 0.016
multi organism cellular process GO:0044764 156 0.016
morphogenesis of a polarized epithelium GO:0001738 3 0.016
regulation of protein maturation GO:1903317 150 0.016
calcium ion transmembrane transport GO:0070588 76 0.016
cerebral cortex cell migration GO:0021795 3 0.016
spermatid development GO:0007286 4 0.016
response to inorganic substance GO:0010035 127 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016

PDE3A disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.046
musculoskeletal system disease DOID:17 223 0.037
disease of metabolism DOID:0014667 295 0.032
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
myopathy DOID:423 104 0.025
muscular disease DOID:0080000 114 0.025
muscle tissue disease DOID:66 113 0.025
inherited metabolic disorder DOID:655 242 0.025
disease of cellular proliferation DOID:14566 174 0.023
central nervous system disease DOID:331 186 0.022
heart disease DOID:114 68 0.022
cancer DOID:162 167 0.022
organ system cancer DOID:0050686 164 0.020
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018