Homo sapiens

23 known processes

NDUFA4

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa

(Aliases: MLRQ,MGC104422,MGC126845,CI-9k,MGC126843,CI-MLRQ,FLJ27440)

NDUFA4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 2 0.812
atp metabolic process GO:0046034 176 0.808
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.712
purine ribonucleotide catabolic process GO:0009154 404 0.678
ribonucleoside catabolic process GO:0042454 406 0.675
post embryonic development GO:0009791 2 0.665
ribonucleoside monophosphate metabolic process GO:0009161 187 0.662
purine ribonucleoside catabolic process GO:0046130 398 0.607
multicellular organismal aging GO:0010259 3 0.607
purine nucleoside catabolic process GO:0006152 398 0.585
nucleoside monophosphate metabolic process GO:0009123 191 0.575
nucleoside triphosphate catabolic process GO:0009143 394 0.569
nucleoside phosphate catabolic process GO:1901292 412 0.529
purine ribonucleoside metabolic process GO:0046128 437 0.521
nucleoside catabolic process GO:0009164 408 0.495
purine nucleotide catabolic process GO:0006195 405 0.493
ribonucleoside monophosphate catabolic process GO:0009158 158 0.480
transmembrane transport GO:0055085 399 0.438
ribonucleoside triphosphate catabolic process GO:0009203 391 0.404
purine nucleoside triphosphate catabolic process GO:0009146 392 0.380
ribonucleoside triphosphate metabolic process GO:0009199 412 0.347
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.339
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.331
purine nucleoside triphosphate metabolic process GO:0009144 412 0.223
cation transmembrane transport GO:0098655 238 0.220
organophosphate catabolic process GO:0046434 430 0.210
nucleoside triphosphate metabolic process GO:0009141 422 0.203
nucleotide catabolic process GO:0009166 408 0.185
nucleoside monophosphate catabolic process GO:0009125 159 0.183
glycosyl compound catabolic process GO:1901658 413 0.169
ion transmembrane transport GO:0034220 338 0.156
purine containing compound catabolic process GO:0072523 411 0.154
atp catabolic process GO:0006200 157 0.144
purine nucleoside monophosphate metabolic process GO:0009126 186 0.134
inorganic ion transmembrane transport GO:0098660 231 0.117
regulation of cellular ketone metabolic process GO:0010565 50 0.115
generation of precursor metabolites and energy GO:0006091 68 0.113
cation transport GO:0006812 331 0.106
proton transport GO:0015992 22 0.094
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.094
ribonucleotide catabolic process GO:0009261 405 0.092
inorganic cation transmembrane transport GO:0098662 194 0.091
cellular amine metabolic process GO:0044106 41 0.086
mating GO:0007618 1 0.085
regulation of neuroblast proliferation GO:1902692 3 0.078
gtp metabolic process GO:0046039 239 0.072
regulation of cellular amine metabolic process GO:0033238 11 0.059
cellular ketone metabolic process GO:0042180 80 0.059
regulation of cellular amino acid metabolic process GO:0006521 6 0.057
negative regulation of proteolysis GO:0045861 132 0.055
amine metabolic process GO:0009308 44 0.054
guanosine containing compound catabolic process GO:1901069 239 0.053
lipid localization GO:0010876 106 0.053
regulation of protein processing GO:0070613 150 0.051
negative regulation of hydrolase activity GO:0051346 182 0.051
intracellular protein transport GO:0006886 270 0.050
alcohol metabolic process GO:0006066 114 0.047
aging GO:0007568 66 0.043
maintenance of location GO:0051235 112 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
cytochrome complex assembly GO:0017004 13 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.040
protein localization to organelle GO:0033365 280 0.039
negative regulation of multicellular organismal process GO:0051241 317 0.038
regulation of proteolysis GO:0030162 293 0.037
reactive oxygen species biosynthetic process GO:1903409 4 0.037
regulation of nucleoside metabolic process GO:0009118 209 0.036
regulation of protein kinase activity GO:0045859 289 0.035
regulation of protein maturation GO:1903317 150 0.035
purine nucleoside monophosphate catabolic process GO:0009128 158 0.033
apoptotic signaling pathway GO:0097190 268 0.033
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
lipid metabolic process GO:0006629 381 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.030
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
protein maturation GO:0051604 233 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
ribose phosphate biosynthetic process GO:0046390 82 0.028
cellular response to oxygen containing compound GO:1901701 276 0.028
regulation of peptidase activity GO:0052547 180 0.028
regulation of transferase activity GO:0051338 355 0.027
nervous system development GO:0007399 293 0.027
pyruvate transmembrane transport GO:1901475 1 0.027
actin cytoskeleton organization GO:0030036 207 0.027
reactive oxygen species metabolic process GO:0072593 75 0.027
negative regulation of neural precursor cell proliferation GO:2000178 1 0.027
regulation of endopeptidase activity GO:0052548 170 0.026
embryo development GO:0009790 123 0.026
response to oxygen containing compound GO:1901700 369 0.026
regulation of growth GO:0040008 165 0.025
ras protein signal transduction GO:0007265 73 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
system process GO:0003008 349 0.024
negative regulation of protein maturation GO:1903318 142 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
defense response GO:0006952 315 0.023
regulation of cellular response to oxidative stress GO:1900407 26 0.023
organic hydroxy compound biosynthetic process GO:1901617 71 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
protein ubiquitination GO:0016567 314 0.023
negative regulation of catabolic process GO:0009895 104 0.023
cytoplasmic transport GO:0016482 379 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.023
cellular modified amino acid biosynthetic process GO:0042398 15 0.023
hydrogen ion transmembrane transport GO:1902600 15 0.022
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.022
negative regulation of cell proliferation GO:0008285 228 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
regulation of protein ubiquitination GO:0031396 95 0.022
reproduction GO:0000003 63 0.022
protein acetylation GO:0006473 116 0.022
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.021
cardiovascular system development GO:0072358 262 0.021
cytokine production GO:0001816 247 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
regulation of kinase activity GO:0043549 314 0.021
hydrogen transport GO:0006818 23 0.020
peptidyl serine modification GO:0018209 106 0.020
purine nucleoside biosynthetic process GO:0042451 23 0.020
positive regulation of synaptic transmission GO:0050806 4 0.020
oxidative phosphorylation GO:0006119 10 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.019
regulation of cellular response to stress GO:0080135 244 0.019
protein processing GO:0016485 226 0.019
negative regulation of peptidase activity GO:0010466 91 0.019
regulation of protein catabolic process GO:0042176 155 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
negative regulation of protein processing GO:0010955 142 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
protein deubiquitination GO:0016579 79 0.018
regulation of defense response GO:0031347 154 0.018
atp synthesis coupled electron transport GO:0042773 4 0.018
positive regulation of apoptotic signaling pathway GO:2001235 70 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
negative regulation of protein deubiquitination GO:0090086 3 0.018
positive regulation of cytokine production GO:0001819 167 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
catecholamine uptake GO:0090493 4 0.018
central nervous system development GO:0007417 123 0.017
regulation of gtpase activity GO:0043087 180 0.017
response to external biotic stimulus GO:0043207 261 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
long term synaptic potentiation GO:0060291 1 0.017
negative regulation of cell death GO:0060548 345 0.017
oxidation reduction process GO:0055114 396 0.017
respiratory electron transport chain GO:0022904 7 0.017
negative regulation of endopeptidase activity GO:0010951 84 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
negative regulation of developmental process GO:0051093 247 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
positive regulation of cell death GO:0010942 263 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.016
circulatory system development GO:0072359 262 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
response to abiotic stimulus GO:0009628 336 0.016
reproductive process GO:0022414 106 0.016
regulation of neurogenesis GO:0050767 82 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
membrane hyperpolarization GO:0060081 1 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
actin filament based process GO:0030029 224 0.015
negative regulation of protein modification process GO:0031400 200 0.015
energy derivation by oxidation of organic compounds GO:0015980 43 0.015
regulation of protein localization GO:0032880 296 0.015
adult locomotory behavior GO:0008344 1 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
cell development GO:0048468 328 0.014
dopamine uptake GO:0090494 4 0.014
negative regulation of kinase activity GO:0033673 106 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
cell growth GO:0016049 160 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
regulation of ion transport GO:0043269 189 0.014
organelle assembly GO:0070925 176 0.014
nuclear transport GO:0051169 179 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
protein k48 linked deubiquitination GO:0071108 19 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
oogenesis GO:0048477 2 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
female gamete generation GO:0007292 2 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
regulation of cytokine production GO:0001817 232 0.013
regulation of response to external stimulus GO:0032101 222 0.013
negative regulation of protein transport GO:0051224 75 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
response to reactive oxygen species GO:0000302 61 0.013
alpha amino acid metabolic process GO:1901605 72 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
brain development GO:0007420 97 0.013
regulation of binding GO:0051098 111 0.012
regulation of androgen receptor activity GO:2000823 3 0.012
negative regulation of transferase activity GO:0051348 124 0.012
blood vessel morphogenesis GO:0048514 162 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
defense response to other organism GO:0098542 129 0.012
regulation of ubiquitin protein transferase activity GO:0051438 28 0.012
positive regulation of transport GO:0051050 336 0.012
catecholamine biosynthetic process GO:0042423 4 0.012
cellular protein complex assembly GO:0043623 188 0.012
cellular protein catabolic process GO:0044257 261 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
cell death in response to oxidative stress GO:0036473 29 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.011
organic hydroxy compound transport GO:0015850 63 0.011
regulation of cell growth GO:0001558 135 0.011
midbrain development GO:0030901 45 0.011
lipid storage GO:0019915 28 0.011
positive regulation of ion transport GO:0043270 87 0.011
negative regulation of cellular response to oxidative stress GO:1900408 18 0.011
positive regulation of oxidative stress induced cell death GO:1903209 5 0.011
response to acid chemical GO:0001101 66 0.011
response to oxygen levels GO:0070482 100 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
positive regulation of developmental process GO:0051094 314 0.011
single organism cellular localization GO:1902580 332 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
regulation of establishment of protein localization GO:0070201 242 0.010
behavior GO:0007610 112 0.010
regulation of cell development GO:0060284 161 0.010
growth GO:0040007 202 0.010
regulation of protein deubiquitination GO:0090085 4 0.010

NDUFA4 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.047
nervous system disease DOID:863 431 0.047
neurodegenerative disease DOID:1289 102 0.013