Homo sapiens

378 known processes

IL6

interleukin 6 (interferon, beta 2)

(Aliases: HGF,IFNB2,IL-6,HSF,BSF2)

IL6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
muscle cell proliferation GO:0033002 35 0.996
regulation of smooth muscle cell proliferation GO:0048660 28 0.994
mature natural killer cell chemotaxis GO:0035782 1 0.987
positive regulation of cytokine production GO:0001819 167 0.976
cytokine production GO:0001816 247 0.973
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.972
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.972
positive regulation of jak stat cascade GO:0046427 35 0.969
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.968
negative regulation of multicellular organismal metabolic process GO:0044252 3 0.968
smooth muscle cell proliferation GO:0048659 28 0.961
positive regulation of acute inflammatory response GO:0002675 2 0.959
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.957
regulation of granzyme b production GO:0071661 1 0.950
positive regulation of macrophage chemotaxis GO:0010759 3 0.947
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.946
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.942
negative regulation of collagen metabolic process GO:0010713 3 0.941
negative regulation of c c chemokine binding GO:2001264 1 0.939
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.937
negative regulation of multicellular organismal process GO:0051241 317 0.935
positive regulation of cell proliferation GO:0008284 301 0.926
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.922
positive regulation of mapk cascade GO:0043410 190 0.915
positive regulation of cellular amine metabolic process GO:0033240 7 0.912
regulation of cellular amino acid metabolic process GO:0006521 6 0.908
regulation of cellular amine metabolic process GO:0033238 11 0.900
jak stat cascade GO:0007259 46 0.897
ciliary neurotrophic factor mediated signaling pathway GO:0070120 5 0.895
positive regulation of t cell apoptotic process GO:0070234 4 0.889
eosinophil activation involved in immune response GO:0002278 2 0.887
lymphocyte migration GO:0072676 28 0.884
cyclic nucleotide metabolic process GO:0009187 82 0.883
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.878
mapk cascade GO:0000165 288 0.876
response to other organism GO:0051707 261 0.869
cellular response to interleukin 1 GO:0071347 35 0.868
negative regulation of chemokine mediated signaling pathway GO:0070100 5 0.858
negative regulation of natural killer cell chemotaxis GO:2000502 1 0.853
t cell migration GO:0072678 16 0.847
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.847
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.841
response to cytokine GO:0034097 232 0.832
response to lipid GO:0033993 206 0.820
chemokine mediated signaling pathway GO:0070098 16 0.819
cytokine mediated signaling pathway GO:0019221 109 0.819
positive regulation of t cell migration GO:2000406 13 0.819
myeloid dendritic cell chemotaxis GO:0002408 3 0.815
t cell chemotaxis GO:0010818 10 0.804
regulation of camp metabolic process GO:0030814 52 0.802
negative regulation of lymphocyte migration GO:2000402 4 0.794
regulation of lymphocyte migration GO:2000401 22 0.792
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.786
positive regulation of immune system process GO:0002684 283 0.784
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.781
hematopoietic or lymphoid organ development GO:0048534 186 0.781
Mouse
erk1 and erk2 cascade GO:0070371 104 0.765
regulation of t cell chemotaxis GO:0010819 7 0.762
peptidyl tyrosine modification GO:0018212 170 0.761
calcium ion transport GO:0006816 147 0.750
lymphocyte chemotaxis GO:0048247 17 0.743
calcium ion homeostasis GO:0055074 122 0.738
viral process GO:0016032 146 0.731
myeloid leukocyte migration GO:0097529 62 0.728
viral life cycle GO:0019058 132 0.726
regulation of camp mediated signaling GO:0043949 13 0.725
disruption by host of symbiont cells GO:0051852 2 0.720
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.716
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.713
positive regulation of cell migration GO:0030335 172 0.711
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.709
response to fibroblast growth factor GO:0071774 39 0.707
regulation of killing of cells of other organism GO:0051709 4 0.701
regulation of chemotaxis GO:0050920 74 0.701
regulation of leukocyte migration GO:0002685 63 0.701
regulation of granzyme a production GO:2000511 1 0.698
regulation of cytokine production GO:0001817 232 0.698
sensory perception of pain GO:0019233 4 0.688
negative regulation of apoptotic process GO:0043066 316 0.685
response to lipopolysaccharide GO:0032496 70 0.677
regulation of mapk cascade GO:0043408 262 0.674
sequestering of calcium ion GO:0051208 17 0.672
response to hormone GO:0009725 175 0.670
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.670
response to abiotic stimulus GO:0009628 336 0.669
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.668
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.664
eosinophil chemotaxis GO:0048245 8 0.662
response to organic cyclic compound GO:0014070 204 0.662
eosinophil degranulation GO:0043308 2 0.659
positive regulation of protein kinase activity GO:0045860 190 0.658
regulation of calcium ion transport into cytosol GO:0010522 33 0.658
response to molecule of bacterial origin GO:0002237 82 0.653
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.653
divalent inorganic cation homeostasis GO:0072507 136 0.652
regulation of jak stat cascade GO:0046425 44 0.640
regulation of lymphocyte chemotaxis GO:1901623 12 0.639
response to bacterium GO:0009617 144 0.639
positive regulation of camp metabolic process GO:0030816 41 0.638
negative regulation of t cell cytokine production GO:0002725 4 0.637
granulocyte migration GO:0097530 40 0.634
regulation of cellular ketone metabolic process GO:0010565 50 0.631
regulation of viral process GO:0050792 103 0.629
regulation of calcium ion transport GO:0051924 79 0.625
regulation of cell motility GO:2000145 299 0.625
leukocyte migration GO:0050900 107 0.625
response to biotic stimulus GO:0009607 276 0.624
positive regulation of epithelial cell proliferation GO:0050679 65 0.619
Mouse
amine metabolic process GO:0009308 44 0.606
myeloid cell differentiation GO:0030099 117 0.601
cell activation GO:0001775 213 0.594
divalent inorganic cation transport GO:0072511 158 0.593
regulation of cell migration GO:0030334 289 0.590
cd8 positive alpha beta t cell activation GO:0036037 3 0.588
cell adhesion GO:0007155 325 0.583
response to oxygen containing compound GO:1901700 369 0.583
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.581
negative regulation of t helper 1 cell activation GO:2000518 1 0.580
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.573
multi organism cellular process GO:0044764 156 0.572
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.570
regulation of cell adhesion GO:0030155 166 0.569
hemopoiesis GO:0030097 180 0.567
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.567
receptor internalization GO:0031623 43 0.565
defense response GO:0006952 315 0.564
regulation of myeloid cell differentiation GO:0045637 81 0.562
granzyme b production GO:0071613 1 0.556
cellular ketone metabolic process GO:0042180 80 0.555
regulation of establishment of protein localization GO:0070201 242 0.554
positive regulation of cell motility GO:2000147 177 0.554
positive regulation of phosphorylation GO:0042327 394 0.552
regulation of viral genome replication GO:0045069 48 0.544
cation transport GO:0006812 331 0.539
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.538
positive regulation of leukocyte migration GO:0002687 46 0.537
positive regulation of ion transport GO:0043270 87 0.537
positive regulation of natural killer cell chemotaxis GO:2000503 5 0.536
positive regulation of behavior GO:0048520 60 0.534
inflammatory response GO:0006954 79 0.531
cellular calcium ion homeostasis GO:0006874 117 0.529
regulation of ion transport GO:0043269 189 0.528
neutrophil migration GO:1990266 25 0.525
cellular response to cytokine stimulus GO:0071345 181 0.524
regulation of chemokine mediated signaling pathway GO:0070099 6 0.524
positive regulation of lymphocyte migration GO:2000403 16 0.523
positive regulation of cell differentiation GO:0045597 211 0.522
Mouse
positive regulation of locomotion GO:0040017 186 0.522
response to interleukin 1 GO:0070555 47 0.521
defense response to other organism GO:0098542 129 0.519
regulation of cellular component movement GO:0051270 334 0.518
regulation of t cell migration GO:2000404 14 0.517
response to radiation GO:0009314 151 0.515
cellular response to oxygen containing compound GO:1901701 276 0.514
negative regulation of programmed cell death GO:0043069 321 0.511
natural killer cell chemotaxis GO:0035747 6 0.509
negative regulation of sequestering of calcium ion GO:0051283 41 0.506
cellular divalent inorganic cation homeostasis GO:0072503 128 0.503
negative regulation of cell proliferation GO:0008285 228 0.499
biological adhesion GO:0022610 331 0.494
g protein coupled receptor signaling pathway GO:0007186 207 0.492
positive regulation of cellular component movement GO:0051272 181 0.491
regulation of c c chemokine binding GO:2001263 1 0.487
response to external biotic stimulus GO:0043207 261 0.486
leukocyte chemotaxis GO:0030595 76 0.486
blood vessel development GO:0001568 172 0.484
positive regulation of camp mediated signaling GO:0043950 10 0.479
immune system development GO:0002520 195 0.479
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.478
leukocyte differentiation GO:0002521 98 0.476
Mouse
response to gamma radiation GO:0010332 14 0.475
signal transduction by phosphorylation GO:0023014 297 0.475
regulation of metal ion transport GO:0010959 120 0.473
interleukin 6 production GO:0032635 37 0.469
cellular response to endogenous stimulus GO:0071495 336 0.468
response to alcohol GO:0097305 64 0.466
positive regulation of cd8 positive alpha beta t cell activation GO:2001187 1 0.466
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.463
response to nitric oxide GO:0071731 4 0.461
positive regulation of chemotaxis GO:0050921 57 0.459
positive regulation of transferase activity GO:0051347 227 0.451
cellular homeostasis GO:0019725 196 0.450
Mouse
chemical homeostasis GO:0048878 306 0.446
Mouse
vasculature development GO:0001944 181 0.443
positive regulation of protein phosphorylation GO:0001934 313 0.440
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.440
regulation of reactive oxygen species metabolic process GO:2000377 41 0.436
regulation of ion homeostasis GO:2000021 73 0.436
regulation of response to wounding GO:1903034 101 0.434
i kappab kinase nf kappab signaling GO:0007249 166 0.431
positive regulation of cell cell adhesion mediated by integrin GO:0033634 3 0.425
acute inflammatory response GO:0002526 21 0.423
cellular response to lipopolysaccharide GO:0071222 57 0.418
regulation of t helper 1 cell activation GO:2000517 1 0.418
cell chemotaxis GO:0060326 112 0.418
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.417
modification of morphology or physiology of other organism GO:0035821 43 0.414
biomineral tissue development GO:0031214 39 0.413
mhc class ii biosynthetic process GO:0045342 4 0.409
positive regulation of calcium ion transport GO:0051928 51 0.402
positive regulation of homeostatic process GO:0032846 47 0.400
regulation of single stranded viral rna replication via double stranded dna intermediate GO:0045091 8 0.398
granzyme a production GO:0035746 1 0.396
regulation of macrophage chemotaxis GO:0010758 4 0.394
camp mediated signaling GO:0019933 23 0.393
response to organonitrogen compound GO:0010243 156 0.393
regulation of leukocyte chemotaxis GO:0002688 46 0.391
regulation of neutrophil chemotaxis GO:0090022 10 0.386
blood vessel morphogenesis GO:0048514 162 0.384
regulation of angiogenesis GO:0045765 92 0.381
chemotaxis GO:0006935 157 0.379
negative regulation of homeostatic process GO:0032845 59 0.378
positive regulation of response to external stimulus GO:0032103 88 0.376
regulation of anatomical structure morphogenesis GO:0022603 286 0.376
peptidyl tyrosine phosphorylation GO:0018108 170 0.374
sequestering of metal ion GO:0051238 24 0.373
response to ionizing radiation GO:0010212 65 0.370
regulation of cell cell adhesion GO:0022407 57 0.370
camp metabolic process GO:0046058 61 0.367
neutrophil chemotaxis GO:0030593 24 0.367
cytosolic calcium ion transport GO:0060401 48 0.365
cytosolic calcium ion homeostasis GO:0051480 89 0.362
cellular cation homeostasis GO:0030003 163 0.359
regulation of behavior GO:0050795 82 0.355
positive regulation of granzyme b production GO:0071663 1 0.355
cellular response to tumor necrosis factor GO:0071356 63 0.351
positive regulation of leukocyte proliferation GO:0070665 48 0.350
regulation of protein kinase activity GO:0045859 289 0.349
establishment of t cell polarity GO:0001768 2 0.348
calcium ion transport into cytosol GO:0060402 48 0.344
taxis GO:0042330 157 0.339
positive regulation of developmental process GO:0051094 314 0.331
Mouse
apoptotic signaling pathway GO:0097190 268 0.331
regulation of granulocyte chemotaxis GO:0071622 16 0.331
regulation of natural killer cell chemotaxis GO:2000501 6 0.330
regulation of protein localization GO:0032880 296 0.327
anatomical structure formation involved in morphogenesis GO:0048646 284 0.327
release of sequestered calcium ion into cytosol GO:0051209 41 0.326
regulation of protein import into nucleus GO:0042306 78 0.324
negative regulation of collagen biosynthetic process GO:0032966 2 0.319
t helper 1 cell activation GO:0035711 1 0.317
disruption of cells of other organism involved in symbiotic interaction GO:0051818 3 0.316
negative regulation of cytokine production GO:0001818 82 0.313
Mouse
divalent metal ion transport GO:0070838 152 0.312
negative regulation of cell death GO:0060548 345 0.311
modification by host of symbiont morphology or physiology GO:0051851 26 0.310
regulation of leukocyte mediated immunity GO:0002703 38 0.308
positive regulation of intracellular protein transport GO:0090316 76 0.307
regulation of locomotion GO:0040012 329 0.307
response to nitrogen compound GO:1901698 184 0.305
negative regulation of cytolysis GO:0045918 3 0.304
positive regulation of granulocyte chemotaxis GO:0071624 9 0.303
regulation of leukocyte differentiation GO:1902105 61 0.302
Mouse
regulation of system process GO:0044057 101 0.300
multi organism metabolic process GO:0044033 41 0.299
positive regulation of kinase activity GO:0033674 204 0.298
regulation of sequestering of calcium ion GO:0051282 41 0.297
positive regulation of intracellular transport GO:0032388 104 0.297
cation homeostasis GO:0055080 189 0.295
regulation of sensory perception of pain GO:0051930 3 0.295
granulocyte chemotaxis GO:0071621 37 0.290
viral genome replication GO:0019079 50 0.290
regulation of protein localization to nucleus GO:1900180 85 0.288
response to growth factor GO:0070848 205 0.285
positive regulation of endothelial cell proliferation GO:0001938 37 0.285
cellular response to biotic stimulus GO:0071216 71 0.283
cellular response to growth factor stimulus GO:0071363 197 0.279
metal ion transport GO:0030001 272 0.276
positive regulation of cytoplasmic transport GO:1903651 82 0.276
regulation of lipid metabolic process GO:0019216 96 0.274
cellular amino acid metabolic process GO:0006520 116 0.273
regulation of cell cell adhesion mediated by integrin GO:0033632 6 0.273
interspecies interaction between organisms GO:0044419 156 0.272
regulation of neutrophil migration GO:1902622 10 0.271
blood coagulation GO:0007596 76 0.270
cellular amine metabolic process GO:0044106 41 0.270
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.268
interleukin 2 production GO:0032623 20 0.268
regulation of homeostatic process GO:0032844 121 0.265
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.265
response to purine containing compound GO:0014074 40 0.264
positive regulation of mononuclear cell proliferation GO:0032946 47 0.263
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.262
extrinsic apoptotic signaling pathway GO:0097191 119 0.262
response to steroid hormone GO:0048545 80 0.262
eosinophil activation GO:0043307 3 0.259
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.258
macrophage chemotaxis GO:0048246 10 0.258
eosinophil mediated immunity GO:0002447 2 0.257
regulation of response to external stimulus GO:0032101 222 0.254
negative regulation of cell differentiation GO:0045596 171 0.253
establishment of lymphocyte polarity GO:0001767 2 0.249
regulation of lymphocyte proliferation GO:0050670 64 0.246
regulation of cell cycle GO:0051726 393 0.244
regulation of nucleotide metabolic process GO:0006140 269 0.244
tyrosine phosphorylation of stat protein GO:0007260 33 0.244
positive regulation of stress activated mapk cascade GO:0032874 60 0.243
positive regulation of protein kinase b signaling GO:0051897 42 0.243
positive regulation of transport GO:0051050 336 0.242
secretion GO:0046903 254 0.242
positive regulation of cell adhesion GO:0045785 84 0.241
cellular response to molecule of bacterial origin GO:0071219 62 0.235
regulation of apoptotic signaling pathway GO:2001233 175 0.233
positive regulation of lymphocyte proliferation GO:0050671 46 0.233
activation of protein kinase activity GO:0032147 90 0.232
regulation of kinase activity GO:0043549 314 0.230
regulation of immune effector process GO:0002697 91 0.228
regulation of endothelial cell proliferation GO:0001936 56 0.224
negative regulation of apoptotic signaling pathway GO:2001234 97 0.220
regulation of cell differentiation GO:0045595 393 0.218
Mouse
response to reactive oxygen species GO:0000302 61 0.214
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.214
cyclic nucleotide mediated signaling GO:0019935 26 0.212
immune response GO:0006955 307 0.212
regulation of monocyte chemotaxis GO:0090025 11 0.211
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.209
regulation of neutrophil mediated cytotoxicity GO:0070948 1 0.209
regulation of multi organism process GO:0043900 157 0.208
negative regulation of myeloid cell differentiation GO:0045638 42 0.205
digestive tract development GO:0048565 75 0.202
regulation of purine nucleotide metabolic process GO:1900542 264 0.201
regulation of secretion GO:0051046 194 0.200
cellular response to lipid GO:0071396 127 0.198
regulation of mononuclear cell proliferation GO:0032944 65 0.197
regulation of cellular response to stress GO:0080135 244 0.195
ion homeostasis GO:0050801 230 0.195
response to camp GO:0051591 25 0.194
positive regulation of vasoconstriction GO:0045907 3 0.194
regulation of protein transport GO:0051223 213 0.193
vesicle mediated transport GO:0016192 371 0.193
glial cell migration GO:0008347 4 0.193
small gtpase mediated signal transduction GO:0007264 78 0.189
positive regulation of killing of cells of other organism GO:0051712 4 0.188
monocyte aggregation GO:0070487 4 0.188
regulation of leukocyte proliferation GO:0070663 67 0.187
negative regulation of cd4 positive alpha beta t cell activation GO:2000515 1 0.186
positive regulation of neutrophil chemotaxis GO:0090023 7 0.186
cellular lipid metabolic process GO:0044255 303 0.186
regulation of secretion by cell GO:1903530 177 0.185
positive regulation of nucleotide metabolic process GO:0045981 230 0.185
cardiovascular system development GO:0072358 262 0.184
immune effector process GO:0002252 159 0.184
positive regulation of protein localization to nucleus GO:1900182 48 0.179
single organism cell adhesion GO:0098602 179 0.178
cellular metal ion homeostasis GO:0006875 146 0.177
metal ion homeostasis GO:0055065 169 0.176
positive regulation of protein import into nucleus GO:0042307 46 0.176
positive regulation of leukocyte chemotaxis GO:0002690 38 0.174
positive regulation of cell adhesion mediated by integrin GO:0033630 9 0.174
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.174
regulation of chemokine production GO:0032642 31 0.173
regulation of vasculature development GO:1901342 97 0.173
negative regulation of mhc class ii biosynthetic process GO:0045347 1 0.173
regulation of erk1 and erk2 cascade GO:0070372 99 0.172
hemostasis GO:0007599 76 0.172
regulation of cell killing GO:0031341 22 0.170
positive regulation of alpha beta t cell proliferation GO:0046641 5 0.170
regulation of lymphocyte activation GO:0051249 103 0.170
endocrine system development GO:0035270 26 0.170
Mouse
negative regulation of bone mineralization GO:0030502 7 0.169
positive regulation of t cell proliferation GO:0042102 33 0.169
activation of phospholipase d activity GO:0031584 3 0.168
cell development GO:0048468 328 0.168
multicellular organismal metabolic process GO:0044236 34 0.167
positive regulation of protein transport GO:0051222 135 0.165
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.164
negative regulation of cellular component movement GO:0051271 106 0.163
interaction with symbiont GO:0051702 26 0.162
amide transport GO:0042886 76 0.160
Mouse
induction of positive chemotaxis GO:0050930 8 0.160
maintenance of location GO:0051235 112 0.159
calcium ion import GO:0070509 23 0.159
receptor metabolic process GO:0043112 81 0.159
chronic inflammatory response GO:0002544 2 0.158
response to organophosphorus GO:0046683 41 0.158
digestive system development GO:0055123 75 0.158
regulation of inflammatory response GO:0050727 46 0.157
neutrophil mediated immunity GO:0002446 4 0.157
ossification GO:0001503 121 0.156
regulation of t cell proliferation GO:0042129 42 0.154
protein kinase b signaling GO:0043491 69 0.153
female gamete generation GO:0007292 2 0.152
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.152
positive regulation of cell cell adhesion GO:0022409 22 0.151
cytoplasmic transport GO:0016482 379 0.151
regulation of protein targeting GO:1903533 91 0.150
bone mineralization GO:0030282 34 0.148
regulation of transferase activity GO:0051338 355 0.147
negative regulation of immune system process GO:0002683 136 0.147
myeloid leukocyte differentiation GO:0002573 60 0.147
regulation of sensory perception GO:0051931 3 0.145
neutrophil mediated cytotoxicity GO:0070942 1 0.144
wound healing GO:0042060 115 0.144
positive regulation of superoxide anion generation GO:0032930 4 0.144
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.143
negative regulation of t cell apoptotic process GO:0070233 4 0.142
positive regulation of nucleotide catabolic process GO:0030813 185 0.141
single organism nuclear import GO:1902593 104 0.141
reactive oxygen species biosynthetic process GO:1903409 4 0.140
response to fatty acid GO:0070542 13 0.138
cell cycle arrest GO:0007050 71 0.138
tube development GO:0035295 125 0.138
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.137
regulation of intracellular transport GO:0032386 195 0.137
positive regulation of catabolic process GO:0009896 310 0.136
single organismal cell cell adhesion GO:0016337 148 0.136
positive regulation of defense response GO:0031349 87 0.136
regeneration GO:0031099 4 0.135
response to corticosteroid GO:0031960 15 0.134
platelet activation GO:0030168 44 0.133
lipid metabolic process GO:0006629 381 0.133
cellular response to organic cyclic compound GO:0071407 127 0.132
response to tumor necrosis factor GO:0034612 76 0.130
muscle cell migration GO:0014812 19 0.130
interferon gamma production GO:0032609 39 0.129
regulation of peptidyl serine phosphorylation of stat protein GO:0033139 3 0.128
rho protein signal transduction GO:0007266 26 0.127
negative regulation of developmental process GO:0051093 247 0.127
reactive oxygen species metabolic process GO:0072593 75 0.127
cellular chemical homeostasis GO:0055082 180 0.126
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.125
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.124
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.122
neurological system process GO:0050877 163 0.121
regulation of dna metabolic process GO:0051052 153 0.120
intracellular protein transport GO:0006886 270 0.120
regulation of defense response GO:0031347 154 0.119
nitrogen compound transport GO:0071705 191 0.118
Mouse
regulation of cytoplasmic transport GO:1903649 149 0.118
positive regulation of potassium ion transport GO:0043268 15 0.116
positive regulation of lymphocyte activation GO:0051251 73 0.116
system process GO:0003008 349 0.115
positive regulation of myosin light chain kinase activity GO:0035505 1 0.114
jnk cascade GO:0007254 80 0.114
regulation of t cell activation GO:0050863 77 0.112
negative regulation of cell cycle GO:0045786 193 0.111
ribonucleotide catabolic process GO:0009261 405 0.111
killing of cells in other organism involved in symbiotic interaction GO:0051883 3 0.111
mononuclear cell proliferation GO:0032943 71 0.111
positive regulation of phospholipase activity GO:0010518 22 0.110
positive regulation of jnk cascade GO:0046330 52 0.110
secretion by cell GO:0032940 226 0.110
leukocyte proliferation GO:0070661 74 0.110
positive regulation of cellular component organization GO:0051130 376 0.109
regulation of epithelial cell proliferation GO:0050678 113 0.109
Mouse
regulation of anatomical structure size GO:0090066 101 0.108
negative regulation of locomotion GO:0040013 118 0.108
regulation of nf kappab import into nucleus GO:0042345 22 0.108
positive regulation of hydrolase activity GO:0051345 331 0.106
regulation of cell adhesion mediated by integrin GO:0033628 22 0.105
positive regulation of nf kappab import into nucleus GO:0042346 13 0.104
leukocyte mediated immunity GO:0002443 59 0.104
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.104
regulation of transcription factor import into nucleus GO:0042990 39 0.104
positive regulation of granzyme a production GO:2000513 1 0.102
positive regulation of apoptotic process GO:0043065 246 0.101
positive regulation of lipid metabolic process GO:0045834 50 0.100
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.100
response to wounding GO:0009611 168 0.100
transmembrane transport GO:0055085 399 0.099
leukocyte activation GO:0045321 164 0.099
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.098
endocrine pancreas development GO:0031018 11 0.097
Mouse
negative regulation of biomineral tissue development GO:0070168 8 0.095
positive chemotaxis GO:0050918 33 0.094
regulation of lipase activity GO:0060191 37 0.094
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.093
regulation of hormone levels GO:0010817 125 0.092
Mouse
positive regulation of cell killing GO:0031343 19 0.091
regulation of interferon gamma production GO:0032649 36 0.091
response to endoplasmic reticulum stress GO:0034976 49 0.090
second messenger mediated signaling GO:0019932 78 0.089
negative regulation of alpha beta t cell activation GO:0046636 3 0.088
response to estrogen GO:0043627 47 0.087
response to oxidative stress GO:0006979 121 0.087
monocyte chemotaxis GO:0002548 20 0.086
inositol lipid mediated signaling GO:0048017 55 0.086
regulation of heterotypic cell cell adhesion GO:0034114 14 0.085
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.085
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 13 0.085
regulation of nucleocytoplasmic transport GO:0046822 98 0.085
protein targeting to nucleus GO:0044744 104 0.084
behavior GO:0007610 112 0.083
cytokine secretion GO:0050663 64 0.083
cell type specific apoptotic process GO:0097285 125 0.083
positive regulation of t cell chemotaxis GO:0010820 7 0.083
regulation of multicellular organismal metabolic process GO:0044246 17 0.083
regulation of astrocyte differentiation GO:0048710 3 0.082
regulation of bone mineralization GO:0030500 29 0.082
negative regulation of ion transport GO:0043271 39 0.082
glycosyl compound catabolic process GO:1901658 413 0.082
establishment of protein localization to organelle GO:0072594 172 0.082
response to ketone GO:1901654 19 0.081
response to oxygen levels GO:0070482 100 0.081
ras protein signal transduction GO:0007265 73 0.081
negative regulation of t cell proliferation GO:0042130 8 0.080
stress activated protein kinase signaling cascade GO:0031098 94 0.080
negative regulation of leukocyte chemotaxis GO:0002689 5 0.080

IL6 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease by infectious agent DOID:0050117 34 0.090