Homo sapiens

2 known processes

PARG

poly (ADP-ribose) glycohydrolase

(Aliases: PARG99,FLJ60456,FLJ60257,FLJ54459)

PARG biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal aging GO:0010259 3 0.116
negative regulation of cellular component organization GO:0051129 235 0.099
purine containing compound catabolic process GO:0072523 411 0.073
vesicle mediated transport GO:0016192 371 0.072
dephosphorylation GO:0016311 209 0.071
cell morphogenesis GO:0000902 296 0.068
positive regulation of developmental process GO:0051094 314 0.057
determination of adult lifespan GO:0008340 2 0.052
cellular macromolecule catabolic process GO:0044265 380 0.050
morphogenesis of embryonic epithelium GO:0016331 4 0.049
lipid metabolic process GO:0006629 381 0.049
nucleoside triphosphate metabolic process GO:0009141 422 0.046
cellular ketone metabolic process GO:0042180 80 0.045
organophosphate catabolic process GO:0046434 430 0.044
glycosyl compound catabolic process GO:1901658 413 0.043
locomotory behavior GO:0007626 1 0.043
negative regulation of cell death GO:0060548 345 0.040
ribonucleoside catabolic process GO:0042454 406 0.040
protein catabolic process GO:0030163 325 0.039
purine nucleoside catabolic process GO:0006152 398 0.039
ras protein signal transduction GO:0007265 73 0.038
protein ubiquitination GO:0016567 314 0.037
growth GO:0040007 202 0.037
female gamete generation GO:0007292 2 0.037
regulation of multi organism process GO:0043900 157 0.035
oogenesis GO:0048477 2 0.035
cytoplasmic transport GO:0016482 379 0.035
nucleoside catabolic process GO:0009164 408 0.035
system process GO:0003008 349 0.035
post embryonic development GO:0009791 2 0.035
nucleoside phosphate catabolic process GO:1901292 412 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.034
negative regulation of intracellular signal transduction GO:1902532 183 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
cellular homeostasis GO:0019725 196 0.034
ion transmembrane transport GO:0034220 338 0.034
apoptotic signaling pathway GO:0097190 268 0.033
cellular amino acid metabolic process GO:0006520 116 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
mapk cascade GO:0000165 288 0.032
regulation of cell cycle GO:0051726 393 0.031
cell projection organization GO:0030030 252 0.030
transmembrane transport GO:0055085 399 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.030
amine metabolic process GO:0009308 44 0.030
regulation of cell cycle process GO:0010564 266 0.029
negative regulation of programmed cell death GO:0043069 321 0.029
mitochondrion organization GO:0007005 156 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
microtubule based process GO:0007017 210 0.029
dna repair GO:0006281 198 0.029
negative regulation of organelle organization GO:0010639 126 0.029
nucleotide catabolic process GO:0009166 408 0.029
negative regulation of catalytic activity GO:0043086 335 0.028
sulfur compound metabolic process GO:0006790 101 0.028
defense response GO:0006952 315 0.027
response to oxygen containing compound GO:1901700 369 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
negative regulation of protein metabolic process GO:0051248 391 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
cellular component morphogenesis GO:0032989 314 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
inorganic ion transmembrane transport GO:0098660 231 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
mitotic cell cycle GO:0000278 326 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
neuromuscular junction development GO:0007528 3 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
purine nucleoside monophosphate catabolic process GO:0009128 158 0.025
cellular amine metabolic process GO:0044106 41 0.025
regulation of protein localization GO:0032880 296 0.025
regulation of cellular response to stress GO:0080135 244 0.024
regulation of mapk cascade GO:0043408 262 0.024
nuclear transport GO:0051169 179 0.024
negative regulation of protein modification process GO:0031400 200 0.024
regulation of cytoskeleton organization GO:0051493 177 0.024
regulation of transferase activity GO:0051338 355 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
small gtpase mediated signal transduction GO:0007264 78 0.024
protein localization to organelle GO:0033365 280 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
rna processing GO:0006396 255 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
regulation of kinase activity GO:0043549 314 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
regulation of growth GO:0040008 165 0.022
meiotic chromosome segregation GO:0045132 4 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
intracellular protein transport GO:0006886 270 0.021
cellular protein complex assembly GO:0043623 188 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
regulation of cellular component movement GO:0051270 334 0.021
nervous system development GO:0007399 293 0.021
positive regulation of transport GO:0051050 336 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
cell growth GO:0016049 160 0.020
chromosome segregation GO:0007059 114 0.020
response to abiotic stimulus GO:0009628 336 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
cellular lipid metabolic process GO:0044255 303 0.020
regulation of dna metabolic process GO:0051052 153 0.020
cell morphogenesis involved in differentiation GO:0000904 144 0.020
cellular protein catabolic process GO:0044257 261 0.020
oocyte development GO:0048599 1 0.020
cell division GO:0051301 168 0.020
nuclear division GO:0000280 128 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
endomembrane system organization GO:0010256 196 0.019
segmentation GO:0035282 4 0.018
immune response GO:0006955 307 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
single organism cellular localization GO:1902580 332 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
epithelium development GO:0060429 227 0.018
positive regulation of catabolic process GO:0009896 310 0.018
response to biotic stimulus GO:0009607 276 0.018
regulation of protein transport GO:0051223 213 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
response to oxidative stress GO:0006979 121 0.018
single organism membrane organization GO:0044802 268 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
protein dephosphorylation GO:0006470 81 0.017
cell part morphogenesis GO:0032990 137 0.017
regulation of cell differentiation GO:0045595 393 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
protein oligomerization GO:0051259 173 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
carbohydrate metabolic process GO:0005975 207 0.017
maintenance of location GO:0051235 112 0.017
mitochondrial membrane organization GO:0007006 40 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
cell development GO:0048468 328 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
chemical homeostasis GO:0048878 306 0.017
adult locomotory behavior GO:0008344 1 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
regulation of cell division GO:0051302 116 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
cation transmembrane transport GO:0098655 238 0.016
organelle fission GO:0048285 149 0.016
regulation of locomotion GO:0040012 329 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
membrane organization GO:0061024 292 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
cell projection morphogenesis GO:0048858 129 0.016
regulation of protein complex assembly GO:0043254 147 0.016
regulation of cell migration GO:0030334 289 0.016
regulation of response to external stimulus GO:0032101 222 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
peripheral nervous system development GO:0007422 2 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
regulation of protein kinase activity GO:0045859 289 0.015
negative regulation of apoptotic signaling pathway GO:2001234 97 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
lipid biosynthetic process GO:0008610 177 0.015
ureteric bud formation GO:0060676 1 0.015
regulation of proteolysis GO:0030162 293 0.015
cytokine production GO:0001816 247 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
wnt signaling pathway GO:0016055 156 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
nitrogen compound transport GO:0071705 191 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
atp metabolic process GO:0046034 176 0.015
memory GO:0007613 3 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
mitotic cell cycle process GO:1903047 286 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
positive regulation of immune system process GO:0002684 283 0.014
mrna metabolic process GO:0016071 175 0.014
regulation of cell growth GO:0001558 135 0.014
protein targeting GO:0006605 187 0.014
cofactor metabolic process GO:0051186 87 0.014
spermatid development GO:0007286 4 0.014
positive regulation of dendrite morphogenesis GO:0050775 3 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
neurological system process GO:0050877 163 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
organelle localization GO:0051640 84 0.014
regulation of cell projection organization GO:0031344 107 0.014
cellular component disassembly GO:0022411 92 0.014
taxis GO:0042330 157 0.014
aging GO:0007568 66 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
peptidyl serine modification GO:0018209 106 0.013
secretion GO:0046903 254 0.013
response to inorganic substance GO:0010035 127 0.013
plasma membrane organization GO:0007009 115 0.013
double strand break repair GO:0006302 101 0.013
covalent chromatin modification GO:0016569 254 0.013
regeneration GO:0031099 4 0.013
positive regulation of dna metabolic process GO:0051054 73 0.013
oocyte differentiation GO:0009994 2 0.013
endosomal transport GO:0016197 129 0.013
apoptotic mitochondrial changes GO:0008637 57 0.013
tripartite regional subdivision GO:0007351 2 0.013
spermatid differentiation GO:0048515 4 0.013
hindbrain development GO:0030902 3 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
receptor metabolic process GO:0043112 81 0.013
innate immune response GO:0045087 178 0.013
generation of neurons GO:0048699 152 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
protein polymerization GO:0051258 71 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
protein homooligomerization GO:0051260 100 0.012
behavior GO:0007610 112 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
regulation of cell development GO:0060284 161 0.012
anion transport GO:0006820 161 0.012
actin cytoskeleton organization GO:0030036 207 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of cell motility GO:2000145 299 0.012
protein maturation GO:0051604 233 0.012
positive regulation of protein transport GO:0051222 135 0.012
negative regulation of multi organism process GO:0043901 92 0.012
fatty acid metabolic process GO:0006631 115 0.012
positive regulation of axon extension GO:0045773 4 0.012
chromatin organization GO:0006325 351 0.012
gastrulation with mouth forming second GO:0001702 1 0.012
regulation of protein catabolic process GO:0042176 155 0.012
negative regulation of transferase activity GO:0051348 124 0.012
response to radiation GO:0009314 151 0.012
cell cycle checkpoint GO:0000075 117 0.012
regulation of cytokine production GO:0001817 232 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
cell adhesion GO:0007155 325 0.012
negative regulation of synaptic transmission GO:0050805 2 0.012
reproductive process GO:0022414 106 0.012
regulation of viral process GO:0050792 103 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
response to external biotic stimulus GO:0043207 261 0.012
negative regulation of kinase activity GO:0033673 106 0.012
response to other organism GO:0051707 261 0.012
atp catabolic process GO:0006200 157 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
cation transport GO:0006812 331 0.011
response to growth factor GO:0070848 205 0.011
neurogenesis GO:0022008 169 0.011
regulation of mitochondrion organization GO:0010821 54 0.011
positive regulation of growth GO:0045927 58 0.011
ion homeostasis GO:0050801 230 0.011
protein depolymerization GO:0051261 30 0.011
organelle assembly GO:0070925 176 0.011
organ formation GO:0048645 3 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
neuron development GO:0048666 113 0.011
compound eye development GO:0048749 1 0.011
multi organism cellular process GO:0044764 156 0.011
mitotic sister chromatid segregation GO:0000070 53 0.011
regulation of meiosis GO:0040020 3 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
interspecies interaction between organisms GO:0044419 156 0.011
protein localization to nucleus GO:0034504 136 0.011
protein processing GO:0016485 226 0.011
anterior posterior axis specification GO:0009948 2 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
phospholipid metabolic process GO:0006644 99 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
response to virus GO:0009615 126 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
protein import GO:0017038 130 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.010
developmental growth GO:0048589 48 0.010
regulation of erk1 and erk2 cascade GO:0070372 99 0.010
actin filament based movement GO:0030048 17 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
endodermal cell fate specification GO:0001714 4 0.010
membrane fusion GO:0061025 43 0.010
positive regulation of kinase activity GO:0033674 204 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
positive regulation of cell projection organization GO:0031346 64 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010

PARG disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.054
musculoskeletal system disease DOID:17 223 0.040
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
central nervous system disease DOID:331 186 0.021
nervous system disease DOID:863 431 0.021
organ system cancer DOID:0050686 164 0.016
inherited metabolic disorder DOID:655 242 0.015
muscular disease DOID:0080000 114 0.014
immune system disease DOID:2914 155 0.013
primary ciliary dyskinesia DOID:9562 27 0.013
hematopoietic system disease DOID:74 100 0.011
endocrine gland cancer DOID:170 26 0.011
bone disease DOID:0080001 88 0.010
connective tissue disease DOID:65 109 0.010