Homo sapiens

31 known processes

HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

(Aliases: HLA-DQB,CELIAC1,IDDM1)

HLA-DQB1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dendritic cell antigen processing and presentation GO:0002468 1 1.000
antigen processing and presentation of peptide antigen GO:0048002 18 0.994
Human Mouse
antigen processing and presentation GO:0019882 33 0.977
Human Mouse
negative regulation of antigen processing and presentation GO:0002578 5 0.922
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.882
Human Mouse
regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002586 3 0.850
regulation of leukocyte proliferation GO:0070663 67 0.767
Human Rat
polysaccharide assembly with mhc class ii protein complex GO:0002506 2 0.763
Human
cellular protein complex assembly GO:0043623 188 0.760
Human
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002581 3 0.758
mhc protein complex assembly GO:0002396 4 0.735
Human
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.729
peptide antigen assembly with mhc class ii protein complex GO:0002503 4 0.723
Human
cytokine production GO:0001816 247 0.716
Human
negative regulation of immune system process GO:0002683 136 0.649
Human Rat
cell activation GO:0001775 213 0.621
Human Mouse Rat
mhc class ii protein complex assembly GO:0002399 4 0.600
Human
regulation of cytokine production GO:0001817 232 0.596
Human
immune response GO:0006955 307 0.557
positive regulation of lymphocyte proliferation GO:0050671 46 0.552
positive regulation of immune system process GO:0002684 283 0.550
Mouse
antigen processing and presentation of polysaccharide antigen via mhc class ii GO:0002505 2 0.548
Human
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.537
Human Mouse
positive regulation of t cell proliferation GO:0042102 33 0.526
peptide antigen assembly with mhc protein complex GO:0002501 4 0.507
Human
lymphocyte mediated immunity GO:0002449 48 0.455
lymphocyte proliferation GO:0046651 70 0.443
Human Rat
defense response GO:0006952 315 0.421
Human Mouse
hemopoiesis GO:0030097 180 0.377
Mouse
lymphocyte activation GO:0046649 133 0.372
Human Mouse Rat
positive regulation of cytokine production GO:0001819 167 0.371
regulation of cellular ketone metabolic process GO:0010565 50 0.360
regulation of interleukin 10 secretion GO:2001179 4 0.352
Human
regulation of t cell proliferation GO:0042129 42 0.345
Human Rat
system process GO:0003008 349 0.342
cellular ketone metabolic process GO:0042180 80 0.317
immune effector process GO:0002252 159 0.307
regulation of lymphocyte proliferation GO:0050670 64 0.307
Human Rat
positive regulation of protein kinase activity GO:0045860 190 0.290
regulation of lymphocyte activation GO:0051249 103 0.272
Human Mouse Rat
positive regulation of cell proliferation GO:0008284 301 0.271
regulation of cell adhesion GO:0030155 166 0.271
cellular homeostasis GO:0019725 196 0.269
Human
t cell proliferation GO:0042098 45 0.268
Human Rat
t cell activation GO:0042110 99 0.263
Human Mouse Rat
humoral immune response GO:0006959 49 0.257
positive regulation of leukocyte activation GO:0002696 80 0.250
Mouse
nitrogen compound transport GO:0071705 191 0.243
Human
cellular macromolecular complex assembly GO:0034622 324 0.240
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.234
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.225
Mouse
negative regulation of antigen processing and presentation of peptide antigen GO:0002584 3 0.219
secretion by cell GO:0032940 226 0.206
Human
negative regulation of cell proliferation GO:0008285 228 0.203
Human Rat
regulation of cell migration GO:0030334 289 0.202
leukocyte activation GO:0045321 164 0.195
Human Mouse Rat
hematopoietic or lymphoid organ development GO:0048534 186 0.193
Mouse
positive regulation of transferase activity GO:0051347 227 0.189
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.188
regulation of mononuclear cell proliferation GO:0032944 65 0.187
Human Rat
cellular amino acid metabolic process GO:0006520 116 0.185
regulation of cellular amino acid metabolic process GO:0006521 6 0.181
positive regulation of lymphocyte activation GO:0051251 73 0.169
Mouse
negative regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002587 2 0.167
protein carbohydrate complex assembly GO:0065006 2 0.165
Human
granulocyte migration GO:0097530 40 0.158
response to cytokine GO:0034097 232 0.158
Mouse
innate immune response GO:0045087 178 0.157
Mouse
cell chemotaxis GO:0060326 112 0.153
biological adhesion GO:0022610 331 0.150
response to oxygen containing compound GO:1901700 369 0.148
Human Rat
regulation of immune response GO:0050776 201 0.141
Human Mouse
positive regulation of response to external stimulus GO:0032103 88 0.140
immune system development GO:0002520 195 0.139
Mouse
b cell homeostasis GO:0001782 1 0.139
inflammatory response to antigenic stimulus GO:0002437 4 0.138
Human
positive regulation of cell migration GO:0030335 172 0.138
positive regulation of protein phosphorylation GO:0001934 313 0.131
neurological system process GO:0050877 163 0.122
regulation of protein localization GO:0032880 296 0.120
Human
regulation of kinase activity GO:0043549 314 0.117
positive regulation of secretion GO:0051047 116 0.116
Human
small molecule biosynthetic process GO:0044283 157 0.116
regulation of antigen processing and presentation GO:0002577 6 0.116
Mouse
cognition GO:0050890 43 0.114
negative regulation of apoptotic signaling pathway GO:2001234 97 0.109
cellular response to cytokine stimulus GO:0071345 181 0.104
Mouse
secretion GO:0046903 254 0.104
Human
negative regulation of peptidase activity GO:0010466 91 0.102
positive regulation of cell motility GO:2000147 177 0.101
positive regulation of developmental process GO:0051094 314 0.100
regulation of leukocyte migration GO:0002685 63 0.097
cytokine mediated signaling pathway GO:0019221 109 0.096
cellular chemical homeostasis GO:0055082 180 0.093
Human
regulation of protein secretion GO:0050708 86 0.092
Human
regulation of chemotaxis GO:0050920 74 0.092
regulation of protein kinase activity GO:0045859 289 0.090
production of molecular mediator of immune response GO:0002440 37 0.089
positive regulation of leukocyte chemotaxis GO:0002690 38 0.089
positive regulation of cellular component movement GO:0051272 181 0.089
positive regulation of behavior GO:0048520 60 0.088
monocarboxylic acid metabolic process GO:0032787 185 0.087
protein secretion GO:0009306 98 0.086
Human
negative regulation of cell differentiation GO:0045596 171 0.082
negative regulation of response to external stimulus GO:0032102 83 0.081
Human
amine metabolic process GO:0009308 44 0.081
positive regulation of cell death GO:0010942 263 0.080
negative regulation of defense response GO:0031348 47 0.080
Human
regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002580 4 0.079
regulation of hormone levels GO:0010817 125 0.077
Human
regulation of locomotion GO:0040012 329 0.077
signal release GO:0023061 70 0.076
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.075
positive regulation of leukocyte migration GO:0002687 46 0.075
regulation of cell motility GO:2000145 299 0.074
positive regulation of cellular component organization GO:0051130 376 0.074
regulation of secretion by cell GO:1903530 177 0.074
Human
regulation of cell activation GO:0050865 125 0.073
Human Mouse Rat
signal transduction by phosphorylation GO:0023014 297 0.071
activation of protein kinase activity GO:0032147 90 0.069
negative regulation of cell adhesion GO:0007162 64 0.069
negative regulation of programmed cell death GO:0043069 321 0.068
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.068
positive regulation of mononuclear cell proliferation GO:0032946 47 0.068
regulation of establishment of protein localization GO:0070201 242 0.068
Human
regulation of secretion GO:0051046 194 0.067
Human
leukocyte mediated immunity GO:0002443 59 0.066
regulation of leukocyte activation GO:0002694 115 0.066
Human Mouse Rat
regulation of leukocyte chemotaxis GO:0002688 46 0.065
negative regulation of cellular component organization GO:0051129 235 0.065
regulation of apoptotic signaling pathway GO:2001233 175 0.065
negative regulation of hydrolase activity GO:0051346 182 0.065
regulation of leukocyte differentiation GO:1902105 61 0.064
negative regulation of apoptotic process GO:0043066 316 0.064
leukocyte differentiation GO:0002521 98 0.063
Mouse
protein maturation GO:0051604 233 0.063
peptidyl tyrosine phosphorylation GO:0018108 170 0.063
protein carbohydrate complex subunit organization GO:0071823 2 0.063
Human
regulation of protein transport GO:0051223 213 0.062
Human
response to molecule of bacterial origin GO:0002237 82 0.061
regulation of defense response GO:0031347 154 0.061
Human
response to biotic stimulus GO:0009607 276 0.060
Human Rat
regulation of cellular response to stress GO:0080135 244 0.060
activation of mapk activity GO:0000187 45 0.058
positive regulation of transport GO:0051050 336 0.057
Human
hormone secretion GO:0046879 65 0.056
Human
negative regulation of transport GO:0051051 176 0.056
cytokine secretion GO:0050663 64 0.054
Human
negative regulation of multicellular organismal process GO:0051241 317 0.054
Human
negative regulation of lymphocyte activation GO:0051250 24 0.054
Human Rat
regulation of cell differentiation GO:0045595 393 0.054
regulation of interferon gamma production GO:0032649 36 0.054
Human
post embryonic development GO:0009791 2 0.052
interleukin 10 production GO:0032613 17 0.051
Human
positive regulation of t cell activation GO:0050870 54 0.050
Mouse
adaptive immune response GO:0002250 49 0.049
positive regulation of chemotaxis GO:0050921 57 0.049
regulation of mapk cascade GO:0043408 262 0.048
response to wounding GO:0009611 168 0.048
Human
lymphocyte apoptotic process GO:0070227 20 0.048
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.047
positive regulation of cell activation GO:0050867 81 0.047
Mouse
neutrophil chemotaxis GO:0030593 24 0.047
peptide transport GO:0015833 74 0.046
Human
protein oligomerization GO:0051259 173 0.046
Human
hormone transport GO:0009914 68 0.046
Human
peptide secretion GO:0002790 51 0.045
Human
regulation of t cell activation GO:0050863 77 0.045
Human Mouse Rat
intrinsic apoptotic signaling pathway GO:0097193 127 0.045
negative regulation of intracellular signal transduction GO:1902532 183 0.045
negative regulation of homeostatic process GO:0032845 59 0.044
negative regulation of cell activation GO:0050866 33 0.044
Human Rat
carboxylic acid biosynthetic process GO:0046394 97 0.044
positive regulation of kinase activity GO:0033674 204 0.044
cellular amine metabolic process GO:0044106 41 0.043
regulation of immune effector process GO:0002697 91 0.043
positive regulation of immune response GO:0050778 159 0.043
Mouse
negative regulation of cytokine production GO:0001818 82 0.042
Human
regulation of protein processing GO:0070613 150 0.042
fatty acid derivative biosynthetic process GO:1901570 18 0.042
negative regulation of protein metabolic process GO:0051248 391 0.041
regulation of anatomical structure morphogenesis GO:0022603 286 0.041
regulation of system process GO:0044057 101 0.041
endocytosis GO:0006897 159 0.041
cell projection organization GO:0030030 252 0.041
peptide hormone secretion GO:0030072 50 0.040
Human
t helper 1 type immune response GO:0042088 8 0.040
Human Mouse
regulation of protein maturation GO:1903317 150 0.040
regulation of transferase activity GO:0051338 355 0.039
interleukin 4 production GO:0032633 7 0.039
Human
regulation of proteolysis GO:0030162 293 0.038
intracellular protein transport GO:0006886 270 0.038
negative regulation of b cell apoptotic process GO:0002903 4 0.038
rho protein signal transduction GO:0007266 26 0.038
fatty acid metabolic process GO:0006631 115 0.038
regulation of cytokine secretion GO:0050707 57 0.037
Human
protein folding GO:0006457 38 0.037
interferon gamma production GO:0032609 39 0.037
Human
chemokine production GO:0032602 32 0.037
unsaturated fatty acid biosynthetic process GO:0006636 21 0.036
negative regulation of immune response GO:0050777 40 0.035
Human
regulation of neutrophil migration GO:1902622 10 0.035
ras protein signal transduction GO:0007265 73 0.035
leukocyte proliferation GO:0070661 74 0.034
Human Rat
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
nucleotide catabolic process GO:0009166 408 0.034
de novo posttranslational protein folding GO:0051084 2 0.034
cell development GO:0048468 328 0.034
positive regulation of secretion by cell GO:1903532 108 0.034
Human
chemical homeostasis GO:0048878 306 0.033
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
ribonucleoside triphosphate metabolic process GO:0009199 412 0.033
metal ion homeostasis GO:0055065 169 0.033
divalent inorganic cation homeostasis GO:0072507 136 0.032
positive regulation of t cell differentiation GO:0045582 11 0.032
peptidyl tyrosine modification GO:0018212 170 0.032
regulation of vesicle mediated transport GO:0060627 130 0.032
prostanoid metabolic process GO:0006692 17 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
regulation of response to dna damage stimulus GO:2001020 94 0.032
cellular response to endogenous stimulus GO:0071495 336 0.032
Rat
lipid biosynthetic process GO:0008610 177 0.032
signal transduction in response to dna damage GO:0042770 57 0.032
cell adhesion GO:0007155 325 0.032
response to hexose GO:0009746 20 0.031
Human
purine ribonucleoside metabolic process GO:0046128 437 0.031
behavior GO:0007610 112 0.031
vesicle mediated transport GO:0016192 371 0.031
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.031
negative regulation of cell substrate adhesion GO:0010812 24 0.030
lipid metabolic process GO:0006629 381 0.030
cellular lipid metabolic process GO:0044255 303 0.030
regulation of response to wounding GO:1903034 101 0.030
Human
cellular response to oxygen containing compound GO:1901701 276 0.030
Human Rat
multicellular organismal aging GO:0010259 3 0.030
small gtpase mediated signal transduction GO:0007264 78 0.029
cellular response to molecule of bacterial origin GO:0071219 62 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
cellular calcium ion homeostasis GO:0006874 117 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
positive regulation of leukocyte differentiation GO:1902107 37 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
taxis GO:0042330 157 0.028
purine containing compound catabolic process GO:0072523 411 0.027
cation transport GO:0006812 331 0.027
negative regulation of cell migration GO:0030336 102 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.027
b cell mediated immunity GO:0019724 10 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
negative regulation of proteolysis GO:0045861 132 0.026
positive regulation of cellular component biogenesis GO:0044089 158 0.026
positive t cell selection GO:0043368 2 0.026
response to tumor necrosis factor GO:0034612 76 0.026
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001188 2 0.026
leukocyte apoptotic process GO:0071887 31 0.025
nucleoside triphosphate metabolic process GO:0009141 422 0.025
regulation of endopeptidase activity GO:0052548 170 0.025
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.025
protein processing GO:0016485 226 0.025
receptor metabolic process GO:0043112 81 0.025
purine nucleotide catabolic process GO:0006195 405 0.025
regulation of erk1 and erk2 cascade GO:0070372 99 0.024
regulation of b cell apoptotic process GO:0002902 5 0.024
cell substrate adhesion GO:0031589 132 0.024
azole transport GO:0045117 4 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.024
positive regulation of protein transport GO:0051222 135 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
regulation of protein binding GO:0043393 66 0.024
positive regulation of hormone secretion GO:0046887 25 0.024
Human
detection of stimulus GO:0051606 85 0.024
Human
erk1 and erk2 cascade GO:0070371 104 0.023
detection of external biotic stimulus GO:0098581 19 0.023
Human
negative regulation of mononuclear cell proliferation GO:0032945 15 0.023
Human Rat
negative regulation of protein maturation GO:1903318 142 0.023
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
chemotaxis GO:0006935 157 0.022
positive regulation of adaptive immune response GO:0002821 21 0.022
Mouse
ribonucleoside catabolic process GO:0042454 406 0.022
defense response to bacterium GO:0042742 63 0.022
oogenesis GO:0048477 2 0.022
determination of adult lifespan GO:0008340 2 0.022
inflammatory response GO:0006954 79 0.022
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
positive regulation of lymphocyte differentiation GO:0045621 13 0.021
regulation of binding GO:0051098 111 0.021
response to external biotic stimulus GO:0043207 261 0.021
Human Rat
wound healing GO:0042060 115 0.021
signal transduction by p53 class mediator GO:0072331 72 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
regulation of b cell proliferation GO:0030888 18 0.021
response to inorganic substance GO:0010035 127 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.020
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.020
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
negative regulation of response to wounding GO:1903035 47 0.020
Human
regulation of hormone secretion GO:0046883 57 0.020
Human
cellular divalent inorganic cation homeostasis GO:0072503 128 0.020
regulation of ras gtpase activity GO:0032318 128 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
mapk cascade GO:0000165 288 0.019
regulation of cell cycle GO:0051726 393 0.019
response to growth factor GO:0070848 205 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.019
neurogenesis GO:0022008 169 0.019
neuromuscular junction development GO:0007528 3 0.019
regulation of body fluid levels GO:0050878 99 0.019
interspecies interaction between organisms GO:0044419 156 0.019
actin filament based process GO:0030029 224 0.019
regulation of response to external stimulus GO:0032101 222 0.019
Human
regulation of dna metabolic process GO:0051052 153 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
cell type specific apoptotic process GO:0097285 125 0.018
negative regulation of protein processing GO:0010955 142 0.018
cellular response to glucose stimulus GO:0071333 10 0.018
Human
female gamete generation GO:0007292 2 0.018
myeloid cell differentiation GO:0030099 117 0.018
cytokine production involved in immune response GO:0002367 27 0.018
t cell selection GO:0045058 4 0.017
actin filament organization GO:0007015 128 0.017
negative regulation of binding GO:0051100 57 0.017
response to glucose GO:0009749 19 0.017
Human
t cell differentiation GO:0030217 29 0.017
cell morphogenesis GO:0000902 296 0.017
negative regulation of leukocyte activation GO:0002695 26 0.017
Human Rat
response to other organism GO:0051707 261 0.017
Human Rat
regulation of nucleotide catabolic process GO:0030811 205 0.017
response to bacterium GO:0009617 144 0.017
Human
mitotic cell cycle process GO:1903047 286 0.017
memory GO:0007613 3 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
apoptotic signaling pathway GO:0097190 268 0.016
protein catabolic process GO:0030163 325 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
gtp metabolic process GO:0046039 239 0.016
regulation of leukocyte apoptotic process GO:2000106 25 0.016
blood coagulation GO:0007596 76 0.016
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.016
single organism cell adhesion GO:0098602 179 0.016
cellular response to tumor necrosis factor GO:0071356 63 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
negative regulation of developmental process GO:0051093 247 0.016
regulation of actin filament based process GO:0032970 141 0.016
regulation of cell projection organization GO:0031344 107 0.016
regulation of protein complex assembly GO:0043254 147 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
cell cycle phase transition GO:0044770 173 0.016
mitotic cell cycle GO:0000278 326 0.016
regulation of tumor necrosis factor production GO:0032680 43 0.016
cell activation involved in immune response GO:0002263 30 0.015
mature b cell apoptotic process GO:0002901 1 0.015
cellular response to oxidative stress GO:0034599 85 0.015
response to radiation GO:0009314 151 0.015
organophosphate catabolic process GO:0046434 430 0.015
response to abiotic stimulus GO:0009628 336 0.015
neuron development GO:0048666 113 0.015
fibroblast proliferation GO:0048144 33 0.015
tumor necrosis factor production GO:0032640 43 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
negative regulation of locomotion GO:0040013 118 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
cellular response to ammonium ion GO:0071242 4 0.015
Rat
carbohydrate metabolic process GO:0005975 207 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
negative regulation of cell death GO:0060548 345 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
mononuclear cell proliferation GO:0032943 71 0.015
Human Rat
positive regulation of cell adhesion GO:0045785 84 0.015
cellular response to external stimulus GO:0071496 111 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
negative regulation of t cell activation GO:0050868 18 0.015
Human Rat
regulation of antigen processing and presentation of peptide antigen GO:0002583 4 0.015
cellular response to interferon gamma GO:0071346 24 0.015
Mouse
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.015
cellular response to lipid GO:0071396 127 0.014
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.014
salivary gland morphogenesis GO:0007435 4 0.014
negative regulation of leukocyte differentiation GO:1902106 24 0.014
negative regulation of cell cycle GO:0045786 193 0.014
cdc42 protein signal transduction GO:0032488 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
lymphocyte migration GO:0072676 28 0.014
positive regulation of peptide hormone secretion GO:0090277 15 0.014
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.014
positive regulation of neutrophil migration GO:1902624 7 0.014
positive regulation of protein complex assembly GO:0031334 86 0.014
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.014
nucleoside catabolic process GO:0009164 408 0.014
positive regulation of acute inflammatory response GO:0002675 2 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
activation of immune response GO:0002253 114 0.014
regulation of gtpase activity GO:0043087 180 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
maintenance of location GO:0051235 112 0.014
regulation of peptide hormone secretion GO:0090276 41 0.014
Human
sensory perception of pain GO:0019233 4 0.013
b cell proliferation GO:0042100 22 0.013
regulation of neutrophil chemotaxis GO:0090022 10 0.013
positive regulation of ras gtpase activity GO:0032320 117 0.013
regulation of behavior GO:0050795 82 0.013
positive regulation of stress activated mapk cascade GO:0032874 60 0.013
gtp catabolic process GO:0006184 237 0.013
chemokine c x c motif ligand 2 production GO:0072567 3 0.013
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.013
Mouse
actin cytoskeleton organization GO:0030036 207 0.013
regulation of cellular component movement GO:0051270 334 0.013
chaperone mediated protein folding GO:0061077 13 0.013
cellular protein catabolic process GO:0044257 261 0.013
response to nitrogen compound GO:1901698 184 0.013
Rat
cell matrix adhesion GO:0007160 85 0.013
response to extracellular stimulus GO:0009991 85 0.013
regulation of b cell activation GO:0050864 24 0.013
modification of morphology or physiology of other organism GO:0035821 43 0.013
cell projection assembly GO:0030031 126 0.013
positive regulation of locomotion GO:0040017 186 0.013
interleukin 1 production GO:0032612 26 0.013
positive thymic t cell selection GO:0045059 1 0.013
regulation of intracellular transport GO:0032386 195 0.013
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.012
positive regulation of granulocyte chemotaxis GO:0071624 9 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.012
negative regulation of t cell proliferation GO:0042130 8 0.012
Human Rat
t cell differentiation in thymus GO:0033077 4 0.012
multi organism cellular process GO:0044764 156 0.012
protein polymerization GO:0051258 71 0.012
inositol lipid mediated signaling GO:0048017 55 0.012
de novo protein folding GO:0006458 2 0.012
regulation of stress activated mapk cascade GO:0032872 84 0.012
dephosphorylation GO:0016311 209 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
negative regulation of neuron projection development GO:0010977 15 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of cytokine production involved in immune response GO:0002718 22 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
lymphocyte chemotaxis GO:0048247 17 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
glycerolipid metabolic process GO:0046486 107 0.011
response to organonitrogen compound GO:0010243 156 0.011
Rat
cellular response to growth factor stimulus GO:0071363 197 0.011
positive regulation of innate immune response GO:0045089 79 0.011
neuron differentiation GO:0030182 138 0.011
leukocyte activation involved in immune response GO:0002366 30 0.011
amide transport GO:0042886 76 0.011
Human
guanosine containing compound metabolic process GO:1901068 244 0.011
myeloid leukocyte differentiation GO:0002573 60 0.011
regulation of rho gtpase activity GO:0032319 66 0.011
unsaturated fatty acid metabolic process GO:0033559 37 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
negative regulation of sequestering of calcium ion GO:0051283 41 0.011
segmentation GO:0035282 4 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
positive regulation of catabolic process GO:0009896 310 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
neuron projection development GO:0031175 106 0.011
regulation of homeostatic process GO:0032844 121 0.011
Human
nervous system development GO:0007399 293 0.011
positive regulation of type 2 immune response GO:0002830 2 0.011
response to fungus GO:0009620 4 0.011
Rat
phospholipid metabolic process GO:0006644 99 0.011
positive regulation of phosphorylation GO:0042327 394 0.011

HLA-DQB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.981
hypersensitivity reaction disease DOID:0060056 25 0.941
hypersensitivity reaction type ii disease DOID:417 19 0.684
musculoskeletal system disease DOID:17 223 0.070
Human
bone disease DOID:0080001 88 0.032
Human
connective tissue disease DOID:65 109 0.032
Human
disease of metabolism DOID:0014667 295 0.018
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013