Homo sapiens

31 known processes

PARN

poly(A)-specific ribonuclease (deadenylation nuclease)

(Aliases: DAN)

PARN biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
primary mirna processing GO:0031053 3 0.143
posttranscriptional regulation of gene expression GO:0010608 213 0.118
vesicle mediated transport GO:0016192 371 0.113
post embryonic development GO:0009791 2 0.103
oogenesis GO:0048477 2 0.101
replication fork processing GO:0031297 13 0.099
cellular macromolecule catabolic process GO:0044265 380 0.076
cellular amino acid metabolic process GO:0006520 116 0.071
regulation of cellular ketone metabolic process GO:0010565 50 0.069
rna interference GO:0016246 4 0.067
cytoplasmic transport GO:0016482 379 0.067
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.066
internal protein amino acid acetylation GO:0006475 101 0.065
determination of adult lifespan GO:0008340 2 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
response to organic cyclic compound GO:0014070 204 0.058
amine metabolic process GO:0009308 44 0.058
regulation of cellular amine metabolic process GO:0033238 11 0.053
positive regulation of cell death GO:0010942 263 0.051
multi organism cellular process GO:0044764 156 0.051
protein acylation GO:0043543 138 0.048
viral process GO:0016032 146 0.048
ncrna processing GO:0034470 83 0.046
gene silencing by mirna GO:0035195 23 0.046
cellular amine metabolic process GO:0044106 41 0.046
nuclear transport GO:0051169 179 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
multicellular organismal aging GO:0010259 3 0.044
female gamete generation GO:0007292 2 0.041
intracellular protein transport GO:0006886 270 0.040
cellular ketone metabolic process GO:0042180 80 0.040
positive regulation of cellular component organization GO:0051130 376 0.040
negative regulation of transport GO:0051051 176 0.038
regulation of cell cycle GO:0051726 393 0.037
nucleocytoplasmic transport GO:0006913 176 0.036
nuclear export GO:0051168 69 0.035
negative regulation of programmed cell death GO:0043069 321 0.035
oocyte differentiation GO:0009994 2 0.035
viral life cycle GO:0019058 132 0.035
endocytosis GO:0006897 159 0.035
protein ubiquitination GO:0016567 314 0.034
lipid metabolic process GO:0006629 381 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
regulation of protein transport GO:0051223 213 0.033
cell development GO:0048468 328 0.033
carbohydrate derivative biosynthetic process GO:1901137 207 0.033
regulation of viral process GO:0050792 103 0.033
nervous system development GO:0007399 293 0.032
cellular response to dna damage stimulus GO:0006974 379 0.032
protein polyubiquitination GO:0000209 110 0.032
negative regulation of cell death GO:0060548 345 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
posttranscriptional gene silencing by rna GO:0035194 25 0.031
organ morphogenesis GO:0009887 147 0.031
regulation of meiosis GO:0040020 3 0.030
regulation of intracellular transport GO:0032386 195 0.030
positive regulation of apoptotic process GO:0043065 246 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
response to nitrogen compound GO:1901698 184 0.030
interspecies interaction between organisms GO:0044419 156 0.029
organophosphate catabolic process GO:0046434 430 0.028
regulation of cell motility GO:2000145 299 0.028
regulation of multi organism process GO:0043900 157 0.028
cellular lipid metabolic process GO:0044255 303 0.028
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.028
negative regulation of apoptotic process GO:0043066 316 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
ncrna metabolic process GO:0034660 108 0.027
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.027
double strand break repair GO:0006302 101 0.027
cell morphogenesis GO:0000902 296 0.026
lipid biosynthetic process GO:0008610 177 0.026
cellular response to dsrna GO:0071359 19 0.026
protein processing GO:0016485 226 0.026
covalent chromatin modification GO:0016569 254 0.026
negative regulation of protein transport GO:0051224 75 0.026
cytokine production GO:0001816 247 0.025
neuromuscular junction development GO:0007528 3 0.025
regulation of cytokine production GO:0001817 232 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
regulation of cellular component movement GO:0051270 334 0.024
neurogenesis GO:0022008 169 0.024
regulation of meiotic cell cycle GO:0051445 4 0.024
posttranscriptional gene silencing GO:0016441 25 0.024
regulation of cell migration GO:0030334 289 0.023
regulation of cytoplasmic transport GO:1903649 149 0.023
dna repair GO:0006281 198 0.023
dna replication GO:0006260 116 0.023
protein glycosylation GO:0006486 62 0.023
ras protein signal transduction GO:0007265 73 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
regulation of translational initiation GO:0006446 24 0.023
regulation of translation GO:0006417 89 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
membrane organization GO:0061024 292 0.022
glycoprotein metabolic process GO:0009100 110 0.022
carbohydrate metabolic process GO:0005975 207 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
peptidyl lysine modification GO:0018205 144 0.022
regulation of locomotion GO:0040012 329 0.022
trna processing GO:0008033 23 0.022
cardiac muscle cell contraction GO:0086003 4 0.022
production of small rna involved in gene silencing by rna GO:0070918 13 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
cell cycle phase transition GO:0044770 173 0.021
rna capping GO:0036260 10 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
actin filament based process GO:0030029 224 0.021
response to dsrna GO:0043331 25 0.020
negative regulation of viral process GO:0048525 66 0.020
dsrna fragmentation GO:0031050 13 0.020
regulation of viral genome replication GO:0045069 48 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
double strand break repair via homologous recombination GO:0000724 50 0.020
segmentation GO:0035282 4 0.020
dna recombination GO:0006310 77 0.020
single organism membrane organization GO:0044802 268 0.020
nitrogen compound transport GO:0071705 191 0.020
negative regulation of cytoplasmic transport GO:1903650 46 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
glycoprotein biosynthetic process GO:0009101 91 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
positive regulation of catabolic process GO:0009896 310 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
protein catabolic process GO:0030163 325 0.019
rna processing GO:0006396 255 0.019
regulation of cell cycle process GO:0010564 266 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
regulation of protein localization GO:0032880 296 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.018
regulation of protein kinase activity GO:0045859 289 0.018
7 methylguanosine mrna capping GO:0006370 7 0.018
cellular component morphogenesis GO:0032989 314 0.018
actin cytoskeleton organization GO:0030036 207 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
regulation of transferase activity GO:0051338 355 0.018
protein maturation GO:0051604 233 0.018
single organism cellular localization GO:1902580 332 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
somatic muscle development GO:0007525 1 0.018
negative regulation of viral genome replication GO:0045071 35 0.017
positive regulation of transport GO:0051050 336 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
associative learning GO:0008306 1 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
receptor mediated endocytosis GO:0006898 84 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
regulation of cell differentiation GO:0045595 393 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
viral genome replication GO:0019079 50 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
negative regulation of cell cycle GO:0045786 193 0.017
mitotic cell cycle process GO:1903047 286 0.017
translation GO:0006412 132 0.017
regulation of protein catabolic process GO:0042176 155 0.016
production of sirna involved in rna interference GO:0030422 3 0.016
growth GO:0040007 202 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of kinase activity GO:0043549 314 0.016
negative regulation of catabolic process GO:0009895 104 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
endomembrane system organization GO:0010256 196 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
positive regulation of organelle organization GO:0010638 195 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
response to oxygen containing compound GO:1901700 369 0.016
cellular protein catabolic process GO:0044257 261 0.016
regulation of mrna metabolic process GO:1903311 53 0.016
small molecule biosynthetic process GO:0044283 157 0.016
oocyte development GO:0048599 1 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
blastoderm segmentation GO:0007350 2 0.015
dna dependent dna replication GO:0006261 44 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
mitotic cell cycle GO:0000278 326 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
atp metabolic process GO:0046034 176 0.015
protein acetylation GO:0006473 116 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.015
endosomal transport GO:0016197 129 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
negative regulation of cell fate commitment GO:0010454 3 0.015
cell projection organization GO:0030030 252 0.015
response to biotic stimulus GO:0009607 276 0.015
neural crest cell development GO:0014032 3 0.015
negative regulation of intracellular transport GO:0032387 60 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
nucleoside catabolic process GO:0009164 408 0.015
recombinational repair GO:0000725 50 0.015
nucleotide catabolic process GO:0009166 408 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
nuclear transcribed mrna catabolic process GO:0000956 48 0.014
apoptotic signaling pathway GO:0097190 268 0.014
positive regulation of cell motility GO:2000147 177 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
cation transport GO:0006812 331 0.014
glycosylation GO:0070085 71 0.014
regulation of proteolysis GO:0030162 293 0.014
translational initiation GO:0006413 48 0.014
actin filament based movement GO:0030048 17 0.014
transmembrane transport GO:0055085 399 0.014
positive regulation of cell cycle GO:0045787 140 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
7 methylguanosine rna capping GO:0009452 9 0.014
organ formation GO:0048645 3 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
rho protein signal transduction GO:0007266 26 0.014
negative regulation of intracellular protein transport GO:0090317 42 0.014
negative regulation of protein modification process GO:0031400 200 0.014
adult locomotory behavior GO:0008344 1 0.014
negative regulation of phosphorylation GO:0042326 174 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
mrna catabolic process GO:0006402 56 0.013
cell projection morphogenesis GO:0048858 129 0.013
signal transduction in response to dna damage GO:0042770 57 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
mitochondrion organization GO:0007005 156 0.013
histone modification GO:0016570 251 0.013
protein methylation GO:0006479 74 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
gtp metabolic process GO:0046039 239 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
cell fate determination GO:0001709 3 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
response to growth factor GO:0070848 205 0.013
negative regulation of developmental process GO:0051093 247 0.013
cell division GO:0051301 168 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
ion transmembrane transport GO:0034220 338 0.013
actin mediated cell contraction GO:0070252 12 0.013
positive regulation of cell migration GO:0030335 172 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
chromatin modification GO:0016568 298 0.012
system process GO:0003008 349 0.012
reproductive process GO:0022414 106 0.012
macromolecule glycosylation GO:0043413 63 0.012
cell part morphogenesis GO:0032990 137 0.012
purine containing compound catabolic process GO:0072523 411 0.012
regulation of gtpase activity GO:0043087 180 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
innate immune response GO:0045087 178 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
membrane lipid metabolic process GO:0006643 53 0.012
negative regulation of protein maturation GO:1903318 142 0.012
regulation of protein processing GO:0070613 150 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
regulation of dna metabolic process GO:0051052 153 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
chemical homeostasis GO:0048878 306 0.012
regulation of response to external stimulus GO:0032101 222 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
response to ionizing radiation GO:0010212 65 0.012
immune response GO:0006955 307 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
defense response GO:0006952 315 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
histone h4 acetylation GO:0043967 47 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
peptidyl serine modification GO:0018209 106 0.012
compound eye development GO:0048749 1 0.012
protein targeting GO:0006605 187 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
regulation of growth GO:0040008 165 0.012
regulation of nuclear division GO:0051783 65 0.012
negative regulation of transferase activity GO:0051348 124 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
cell projection assembly GO:0030031 126 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
generation of neurons GO:0048699 152 0.012
protein modification by small protein conjugation GO:0032446 342 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
response to lipid GO:0033993 206 0.011
regulation of peptidase activity GO:0052547 180 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of immune response GO:0050776 201 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
anion transport GO:0006820 161 0.011
tripartite regional subdivision GO:0007351 2 0.011
protein localization to organelle GO:0033365 280 0.011
glycerolipid metabolic process GO:0046486 107 0.011
locomotory behavior GO:0007626 1 0.011
cell growth GO:0016049 160 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
single organism reproductive process GO:0044702 98 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
golgi vesicle transport GO:0048193 80 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
cytokinesis GO:0000910 96 0.011
metal ion transport GO:0030001 272 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
secretion by cell GO:0032940 226 0.011
positive regulation of immune system process GO:0002684 283 0.011
rna catabolic process GO:0006401 71 0.011
mrna metabolic process GO:0016071 175 0.011
regulation of protein maturation GO:1903317 150 0.011
neurological system process GO:0050877 163 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
response to external biotic stimulus GO:0043207 261 0.011
motor neuron axon guidance GO:0008045 2 0.011
response to other organism GO:0051707 261 0.011
cell adhesion GO:0007155 325 0.011
anterior posterior axis specification GO:0009948 2 0.011
immune system development GO:0002520 195 0.011
cellular response to endogenous stimulus GO:0071495 336 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
peripheral nervous system development GO:0007422 2 0.010
negative regulation of proteolysis GO:0045861 132 0.010
cardiac muscle contraction GO:0060048 34 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
striated muscle contraction GO:0006941 52 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
phospholipid metabolic process GO:0006644 99 0.010
hindbrain development GO:0030902 3 0.010
negative regulation of multi organism process GO:0043901 92 0.010
response to hormone GO:0009725 175 0.010
long term memory GO:0007616 2 0.010
post embryonic organ development GO:0048569 1 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
response to salt stress GO:0009651 3 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
guanosine containing compound metabolic process GO:1901068 244 0.010

PARN disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.054
inherited metabolic disorder DOID:655 242 0.038
cancer DOID:162 167 0.035
disease of cellular proliferation DOID:14566 174 0.035
organ system cancer DOID:0050686 164 0.035
immune system disease DOID:2914 155 0.035
central nervous system disease DOID:331 186 0.032
nervous system disease DOID:863 431 0.032
carbohydrate metabolic disorder DOID:2978 55 0.020
musculoskeletal system disease DOID:17 223 0.020
neuropathy DOID:870 52 0.019
neurodegenerative disease DOID:1289 102 0.018
breast cancer DOID:1612 21 0.015
thoracic cancer DOID:5093 21 0.015
sensory system disease DOID:0050155 203 0.012
myopathy DOID:423 104 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
congenital disorder of glycosylation type i DOID:0050570 16 0.011
congenital disorder of glycosylation DOID:5212 26 0.011
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011
connective tissue disease DOID:65 109 0.010