Homo sapiens

36 known processes

TLR1

toll-like receptor 1

(Aliases: CD281,DKFZp547I0610,KIAA0012,MGC104956,TIL,MGC126311,rsc786,TIL. LPRS5,DKFZp564I0682,MGC126312)

TLR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.990
Human
cellular response to triacyl bacterial lipopeptide GO:0071727 2 0.974
response to triacyl bacterial lipopeptide GO:0071725 2 0.974
response to diacyl bacterial lipopeptide GO:0071724 2 0.880
Human
interferon alpha biosynthetic process GO:0045349 4 0.758
Human
detection of diacyl bacterial lipopeptide GO:0042496 2 0.599
Human
positive regulation of immune system process GO:0002684 283 0.592
Human
detection of bacterial lipoprotein GO:0042494 3 0.590
cellular response to diacyl bacterial lipopeptide GO:0071726 2 0.568
Human
immune response GO:0006955 307 0.402
Human
defense response GO:0006952 315 0.400
Human Mouse
detection of biotic stimulus GO:0009595 21 0.383
detection of lipopolysaccharide GO:0032497 3 0.359
Human
positive regulation of response to external stimulus GO:0032103 88 0.352
Human
positive regulation of defense response GO:0031349 87 0.348
Human
regulation of response to external stimulus GO:0032101 222 0.341
Human
cellular response to molecule of bacterial origin GO:0071219 62 0.332
pattern recognition receptor signaling pathway GO:0002221 48 0.322
Human
regulation of interferon beta biosynthetic process GO:0045357 4 0.313
Human
response to external biotic stimulus GO:0043207 261 0.309
detection of chemical stimulus GO:0009593 55 0.295
positive regulation of transport GO:0051050 336 0.287
Human
response to biotic stimulus GO:0009607 276 0.280
innate immune response GO:0045087 178 0.266
Human
detection of bacterial lipopeptide GO:0070340 3 0.262
response to bacterium GO:0009617 144 0.261
activation of immune response GO:0002253 114 0.250
Human
response to other organism GO:0051707 261 0.243
detection of molecule of bacterial origin GO:0032490 10 0.231
positive regulation of immune response GO:0050778 159 0.224
Human
cytokine production GO:0001816 247 0.213
Human Mouse
positive regulation of toll like receptor signaling pathway GO:0034123 10 0.200
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.198
positive regulation of protein transport GO:0051222 135 0.194
Human
defense response to virus GO:0051607 71 0.178
Human
cellular response to bacterial lipoprotein GO:0071220 3 0.163
regulation of establishment of protein localization GO:0070201 242 0.159
Human
regulation of immune response GO:0050776 201 0.153
Human
positive regulation of cytokine production GO:0001819 167 0.153
Human Mouse
defense response to other organism GO:0098542 129 0.152
Human
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.142
Human Mouse
response to oxygen containing compound GO:1901700 369 0.142
Human
nitrogen compound transport GO:0071705 191 0.141
Human
positive regulation of phosphorylation GO:0042327 394 0.131
Human
detection of stimulus GO:0051606 85 0.117
cellular response to lipopolysaccharide GO:0071222 57 0.116
Human
response to abiotic stimulus GO:0009628 336 0.115
Human
immune response activating signal transduction GO:0002757 90 0.111
Human
response to lipid GO:0033993 206 0.109
Human
regulation of defense response GO:0031347 154 0.108
Human
regulation of interferon alpha biosynthetic process GO:0045354 4 0.105
Human
cellular amino acid metabolic process GO:0006520 116 0.104
regulation of innate immune response GO:0045088 97 0.100
Human
detection of external biotic stimulus GO:0098581 19 0.099
activation of innate immune response GO:0002218 55 0.098
Human
response to bacterial lipopeptide GO:0070339 3 0.098
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.095
Human
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.094
Human
regulation of protein transport GO:0051223 213 0.094
Human
positive regulation of map kinase activity GO:0043406 80 0.091
Human
cation transport GO:0006812 331 0.090
positive regulation of innate immune response GO:0045089 79 0.088
Human
mapk cascade GO:0000165 288 0.088
Human
leukocyte activation GO:0045321 164 0.086
Human
positive regulation of transferase activity GO:0051347 227 0.086
Human
protein localization to organelle GO:0033365 280 0.082
Human
defense response to bacterium GO:0042742 63 0.078
system process GO:0003008 349 0.078
cytoplasmic transport GO:0016482 379 0.077
Human
regulation of protein secretion GO:0050708 86 0.077
interferon beta biosynthetic process GO:0045350 4 0.076
Human
immune effector process GO:0002252 159 0.075
Human
cellular response to mechanical stimulus GO:0071260 39 0.074
Human
cell activation GO:0001775 213 0.073
Human
immune response regulating signaling pathway GO:0002764 97 0.071
Human
cellular ketone metabolic process GO:0042180 80 0.071
inflammatory response GO:0006954 79 0.070
positive regulation of hydrolase activity GO:0051345 331 0.069
response to wounding GO:0009611 168 0.067
signal transduction by phosphorylation GO:0023014 297 0.065
Human
adaptive immune response GO:0002250 49 0.065
i kappab phosphorylation GO:0007252 7 0.064
Human
regulation of response to biotic stimulus GO:0002831 55 0.061
Human
cellular response to lipid GO:0071396 127 0.060
Human
regulation of kinase activity GO:0043549 314 0.060
Human
response to virus GO:0009615 126 0.060
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.059
Human
response to molecule of bacterial origin GO:0002237 82 0.058
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.056
Human
coagulation GO:0050817 78 0.055
wound healing GO:0042060 115 0.054
cellular lipid metabolic process GO:0044255 303 0.054
innate immune response activating signal transduction GO:0002758 48 0.053
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.052
regulation of cellular ketone metabolic process GO:0010565 50 0.051
regulation of protein serine threonine kinase activity GO:0071900 179 0.051
Human
chemotaxis GO:0006935 157 0.051
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.050
Human
lymphocyte activation GO:0046649 133 0.050
cellular response to oxygen containing compound GO:1901701 276 0.050
Human
regulation of protein localization GO:0032880 296 0.050
Human
regulation of transferase activity GO:0051338 355 0.050
Human
lipid metabolic process GO:0006629 381 0.049
cellular amine metabolic process GO:0044106 41 0.049
positive regulation of protein kinase activity GO:0045860 190 0.049
Human
positive regulation of cellular component organization GO:0051130 376 0.048
regulation of cytokine production GO:0001817 232 0.048
Human Mouse
positive regulation of cell activation GO:0050867 81 0.048
monocarboxylic acid metabolic process GO:0032787 185 0.047
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.047
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.047
secretion GO:0046903 254 0.047
regulation of intracellular transport GO:0032386 195 0.047
Human
multicellular organismal aging GO:0010259 3 0.046
response to lipopolysaccharide GO:0032496 70 0.046
Human
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.045
positive regulation of intracellular protein transport GO:0090316 76 0.044
Human
immune system development GO:0002520 195 0.044
positive regulation of kinase activity GO:0033674 204 0.043
Human
nucleotide catabolic process GO:0009166 408 0.043
chemokine production GO:0032602 32 0.043
Human
determination of adult lifespan GO:0008340 2 0.042
regulation of nucleotide metabolic process GO:0006140 269 0.042
protein targeting GO:0006605 187 0.041
Human
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.041
Human Mouse
regulation of cell cycle GO:0051726 393 0.040
positive regulation of mapk cascade GO:0043410 190 0.040
Human
regulation of mapk cascade GO:0043408 262 0.040
Human
amine metabolic process GO:0009308 44 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
response to bacterial lipoprotein GO:0032493 3 0.039
positive regulation of intracellular transport GO:0032388 104 0.039
Human
regulation of cellular amine metabolic process GO:0033238 11 0.039
positive regulation of developmental process GO:0051094 314 0.039
regulation of response to wounding GO:1903034 101 0.038
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.038
Human Mouse
positive regulation of interferon beta biosynthetic process GO:0045359 4 0.038
Human
female gamete generation GO:0007292 2 0.038
ribonucleoside catabolic process GO:0042454 406 0.037
positive regulation of programmed cell death GO:0043068 249 0.036
intracellular protein transport GO:0006886 270 0.036
Human
secretion by cell GO:0032940 226 0.036
post embryonic development GO:0009791 2 0.036
compound eye development GO:0048749 1 0.036
amide transport GO:0042886 76 0.036
Human
protein catabolic process GO:0030163 325 0.035
detection of bacterium GO:0016045 13 0.035
positive regulation of cell death GO:0010942 263 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
i kappab kinase nf kappab signaling GO:0007249 166 0.035
Human
regulation of erk1 and erk2 cascade GO:0070372 99 0.034
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.034
Human
positive regulation of multi organism process GO:0043902 56 0.034
Human
blood coagulation GO:0007596 76 0.034
single organism cellular localization GO:1902580 332 0.034
Human
small gtpase mediated signal transduction GO:0007264 78 0.034
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
positive regulation of interferon gamma production GO:0032729 26 0.034
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.033
protein import GO:0017038 130 0.033
Human
glycosyl compound catabolic process GO:1901658 413 0.033
regulation of cellular response to stress GO:0080135 244 0.033
Human
hemostasis GO:0007599 76 0.033
negative regulation of programmed cell death GO:0043069 321 0.033
regulation of proteolysis GO:0030162 293 0.032
memory GO:0007613 3 0.032
neurological system process GO:0050877 163 0.032
nuclear transport GO:0051169 179 0.032
Human
nucleocytoplasmic transport GO:0006913 176 0.032
Human
response to decreased oxygen levels GO:0036293 96 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
positive regulation of interleukin 8 production GO:0032757 36 0.031
Human
regulation of protein targeting GO:1903533 91 0.031
Human
regulation of cell activation GO:0050865 125 0.031
vesicle mediated transport GO:0016192 371 0.031
organonitrogen compound biosynthetic process GO:1901566 200 0.031
purine containing compound catabolic process GO:0072523 411 0.031
positive regulation of cell differentiation GO:0045597 211 0.031
regulation of cytoplasmic transport GO:1903649 149 0.031
Human
regulation of inflammatory response GO:0050727 46 0.031
regulation of immune effector process GO:0002697 91 0.030
cellular macromolecule catabolic process GO:0044265 380 0.030
positive regulation of acute inflammatory response GO:0002675 2 0.030
reactive nitrogen species metabolic process GO:2001057 3 0.030
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.030
Human
regulation of body fluid levels GO:0050878 99 0.030
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.030
leukocyte proliferation GO:0070661 74 0.029
regulation of tumor necrosis factor production GO:0032680 43 0.029
Human Mouse
protein targeting to nucleus GO:0044744 104 0.029
Human
cell projection organization GO:0030030 252 0.029
protein maturation GO:0051604 233 0.028
positive regulation of immune effector process GO:0002699 40 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
protein autoprocessing GO:0016540 4 0.028
regulation of multi organism process GO:0043900 157 0.028
Human
single organism nuclear import GO:1902593 104 0.028
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
regulation of secretion GO:0051046 194 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
alcohol metabolic process GO:0006066 114 0.028
reactive oxygen species biosynthetic process GO:1903409 4 0.028
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
ras protein signal transduction GO:0007265 73 0.027
regulation of cell cycle process GO:0010564 266 0.027
cell type specific apoptotic process GO:0097285 125 0.027
positive regulation of cell proliferation GO:0008284 301 0.027
positive regulation of lymphocyte activation GO:0051251 73 0.027
interleukin 6 production GO:0032635 37 0.027
Human Mouse
cellular response to biotic stimulus GO:0071216 71 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
Human
sensory perception of pain GO:0019233 4 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.026
detection of triacyl bacterial lipopeptide GO:0042495 2 0.026
response to hypoxia GO:0001666 96 0.026
regulation of lymphocyte proliferation GO:0050670 64 0.026
cellular response to abiotic stimulus GO:0071214 117 0.026
Human
regulation of leukocyte proliferation GO:0070663 67 0.026
interferon beta production GO:0032608 23 0.026
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
positive regulation of locomotion GO:0040017 186 0.026
lymphocyte mediated immunity GO:0002449 48 0.025
positive regulation of cytoplasmic transport GO:1903651 82 0.025
Human
cellular modified amino acid metabolic process GO:0006575 64 0.025
complement receptor mediated signaling pathway GO:0002430 3 0.025
regulation of nucleocytoplasmic transport GO:0046822 98 0.025
Human
protein processing GO:0016485 226 0.025
exocytosis GO:0006887 71 0.025
response to fungus GO:0009620 4 0.025
cellular protein catabolic process GO:0044257 261 0.025
type i interferon biosynthetic process GO:0045351 4 0.025
Human
protein secretion GO:0009306 98 0.025
positive regulation of interferon alpha biosynthetic process GO:0045356 4 0.025
Human
positive regulation of protein localization to nucleus GO:1900182 48 0.025
Human
negative regulation of cell proliferation GO:0008285 228 0.025
taxis GO:0042330 157 0.025
actin filament based process GO:0030029 224 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
negative regulation of apoptotic process GO:0043066 316 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
peripheral nervous system development GO:0007422 2 0.025
establishment of protein localization to organelle GO:0072594 172 0.024
Human
interferon gamma biosynthetic process GO:0042095 8 0.024
Human
small molecule biosynthetic process GO:0044283 157 0.024
regulation of peptide transport GO:0090087 62 0.024
Human
regulation of antimicrobial humoral response GO:0002759 1 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
Human
cellular response to external stimulus GO:0071496 111 0.024
Human
tumor necrosis factor production GO:0032640 43 0.024
Human Mouse
platelet activation GO:0030168 44 0.024
regulation of chemokine production GO:0032642 31 0.024
Human
regulation of cell motility GO:2000145 299 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
regulation of cell differentiation GO:0045595 393 0.024
negative regulation of immune system process GO:0002683 136 0.024
regulation of interleukin 1 production GO:0032652 21 0.024
oogenesis GO:0048477 2 0.023
cell chemotaxis GO:0060326 112 0.023
positive regulation of proteolysis GO:0045862 142 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
positive regulation of type i interferon production GO:0032481 20 0.023
Human
blood vessel development GO:0001568 172 0.023
protein import into nucleus GO:0006606 104 0.023
Human
regulation of cell adhesion GO:0030155 166 0.023
response to cytokine GO:0034097 232 0.023
macrophage activation GO:0042116 12 0.023
Human
organophosphate catabolic process GO:0046434 430 0.023
protein localization to nucleus GO:0034504 136 0.023
Human
regulation of secretion by cell GO:1903530 177 0.023
myeloid leukocyte activation GO:0002274 34 0.023
Human
regulation of protein import into nucleus GO:0042306 78 0.022
Human
mitotic cell cycle GO:0000278 326 0.022
toll like receptor signaling pathway GO:0002224 25 0.022
Human
chromatin organization GO:0006325 351 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
biological adhesion GO:0022610 331 0.022
regulation of transcription factor import into nucleus GO:0042990 39 0.022
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
negative regulation of cell death GO:0060548 345 0.022
regulation of cytokine biosynthetic process GO:0042035 35 0.021
Human Mouse
metal ion transport GO:0030001 272 0.021
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 5 0.021
Human Mouse
regulation of cellular component movement GO:0051270 334 0.021
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.021
apoptotic signaling pathway GO:0097190 268 0.021
lipid biosynthetic process GO:0008610 177 0.021
response to oxygen levels GO:0070482 100 0.021
negative regulation of protein maturation GO:1903318 142 0.021
regulation of peptidase activity GO:0052547 180 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
spermatid development GO:0007286 4 0.021
positive regulation of interferon gamma biosynthetic process GO:0045078 7 0.021
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
nucleoside catabolic process GO:0009164 408 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
positive regulation of catabolic process GO:0009896 310 0.021
positive regulation of interleukin 6 production GO:0032755 21 0.021
Human Mouse
cellular response to endogenous stimulus GO:0071495 336 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
positive regulation of stress activated mapk cascade GO:0032874 60 0.020
Human
positive regulation of response to wounding GO:1903036 28 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.020
Human
leukocyte mediated immunity GO:0002443 59 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.020
response to radiation GO:0009314 151 0.020
spermatid differentiation GO:0048515 4 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.020
positive regulation of secretion GO:0051047 116 0.020
melanin metabolic process GO:0006582 1 0.020
divalent metal ion transport GO:0070838 152 0.020
regulation of map kinase activity GO:0043405 108 0.020
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
regulation of protein kinase activity GO:0045859 289 0.020
Human
cellular homeostasis GO:0019725 196 0.020
histone modification GO:0016570 251 0.020
single organism membrane organization GO:0044802 268 0.019
positive regulation of response to biotic stimulus GO:0002833 18 0.019
Human
cell morphogenesis GO:0000902 296 0.019
peptide transport GO:0015833 74 0.019
Human
membrane organization GO:0061024 292 0.019
endocytosis GO:0006897 159 0.019
regulation of type i interferon production GO:0032479 26 0.019
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
regulation of ion transport GO:0043269 189 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
rhythmic behavior GO:0007622 2 0.019
regulation of lymphocyte activation GO:0051249 103 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
interleukin 10 production GO:0032613 17 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
regulation of vasculature development GO:1901342 97 0.019
cell adhesion GO:0007155 325 0.019
regulation of protein localization to nucleus GO:1900180 85 0.019
Human
striated muscle contraction GO:0006941 52 0.018
blood vessel morphogenesis GO:0048514 162 0.018
regulation of protein processing GO:0070613 150 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
protein oligomerization GO:0051259 173 0.018
carbohydrate metabolic process GO:0005975 207 0.018
regulation of hemostasis GO:1900046 42 0.018
response to hormone GO:0009725 175 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
endomembrane system organization GO:0010256 196 0.018
activation of protein kinase activity GO:0032147 90 0.018
hemopoiesis GO:0030097 180 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
serotonin transport GO:0006837 3 0.018
chemical homeostasis GO:0048878 306 0.018
cation homeostasis GO:0055080 189 0.018
positive regulation of interleukin 8 biosynthetic process GO:0045416 8 0.018
Human
regulation of membrane potential GO:0042391 95 0.018
dephosphorylation GO:0016311 209 0.018
sulfur compound metabolic process GO:0006790 101 0.018
circadian behavior GO:0048512 2 0.017
positive regulation of protein secretion GO:0050714 60 0.017
response to organic cyclic compound GO:0014070 204 0.017
cell cycle phase transition GO:0044770 173 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
zymogen activation GO:0031638 70 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
negative regulation of cell cycle GO:0045786 193 0.017
anatomical structure homeostasis GO:0060249 100 0.017
serotonin secretion GO:0001820 1 0.017
regulation of adaptive immune response GO:0002819 33 0.017
positive regulation of b cell mediated immunity GO:0002714 4 0.017
cellular amide metabolic process GO:0043603 69 0.017
protein ubiquitination GO:0016567 314 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
syncytium formation by plasma membrane fusion GO:0000768 2 0.017
positive regulation of secretion by cell GO:1903532 108 0.016
positive regulation of lymphocyte proliferation GO:0050671 46 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.016
Human
cofactor metabolic process GO:0051186 87 0.016
positive regulation of leukocyte proliferation GO:0070665 48 0.016
positive regulation of astrocyte chemotaxis GO:2000464 1 0.016
regulation of wound healing GO:0061041 56 0.016
interleukin 1 production GO:0032612 26 0.016
cellular chemical homeostasis GO:0055082 180 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
circulatory system development GO:0072359 262 0.016
epithelial cell migration GO:0010631 119 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
regulation of cell migration GO:0030334 289 0.016
response to metal ion GO:0010038 84 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
response to lipoteichoic acid GO:0070391 3 0.016
regulation of interleukin 6 production GO:0032675 37 0.016
Human Mouse
stress activated mapk cascade GO:0051403 93 0.015
Human
positive regulation of vasoconstriction GO:0045907 3 0.015
heparin metabolic process GO:0030202 1 0.015
intracellular receptor signaling pathway GO:0030522 104 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
sequestering of metal ion GO:0051238 24 0.015
response to toxic substance GO:0009636 37 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
cell development GO:0048468 328 0.015
oxidation reduction process GO:0055114 396 0.015
cellular component morphogenesis GO:0032989 314 0.015
b cell activation GO:0042113 33 0.015
regulation of protein complex assembly GO:0043254 147 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
cellular protein complex assembly GO:0043623 188 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
regulation of cytokine secretion GO:0050707 57 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
regulation of behavior GO:0050795 82 0.015
cellular ion homeostasis GO:0006873 168 0.015
locomotory behavior GO:0007626 1 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.015
mononuclear cell proliferation GO:0032943 71 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
calcium ion transport GO:0006816 147 0.015
rho protein signal transduction GO:0007266 26 0.015
positive regulation of inflammatory response GO:0050729 10 0.015
toxin transport GO:1901998 4 0.015
negative regulation of transport GO:0051051 176 0.014
regulation of leukocyte activation GO:0002694 115 0.014
cellular cation homeostasis GO:0030003 163 0.014
nuclear import GO:0051170 106 0.014
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
neuromuscular junction development GO:0007528 3 0.014
regulation of interferon gamma biosynthetic process GO:0045072 8 0.014
Human
maintenance of location GO:0051235 112 0.014
coenzyme metabolic process GO:0006732 65 0.014
regulation of stress activated mapk cascade GO:0032872 84 0.014
Human
interleukin 17 production GO:0032620 12 0.014
developmental programmed cell death GO:0010623 3 0.014
plasma membrane organization GO:0007009 115 0.014
interferon gamma production GO:0032609 39 0.014
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.014
negative regulation of protein processing GO:0010955 142 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
humoral immune response GO:0006959 49 0.014
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.014
circadian sleep wake cycle GO:0042745 2 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
regulation of system process GO:0044057 101 0.014
regulation of actin filament based process GO:0032970 141 0.014
interleukin 12 biosynthetic process GO:0042090 1 0.014
Human
response to organonitrogen compound GO:0010243 156 0.014
endosomal transport GO:0016197 129 0.014
organic acid biosynthetic process GO:0016053 97 0.014
vasculature development GO:0001944 181 0.014
positive regulation of apoptotic signaling pathway GO:2001235 70 0.014
regulation of interleukin 8 production GO:0032677 49 0.014
Human
regulation of dna metabolic process GO:0051052 153 0.014
regulation of gtp catabolic process GO:0033124 180 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
myoblast fusion GO:0007520 1 0.013
cellular response to bacterial lipopeptide GO:0071221 3 0.013
fatty acid metabolic process GO:0006631 115 0.013
interleukin 8 production GO:0032637 51 0.013
Human
response to nitrogen compound GO:1901698 184 0.013
positive regulation of humoral immune response GO:0002922 3 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
regulation of coagulation GO:0050818 44 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
gtp catabolic process GO:0006184 237 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
multicellular organismal metabolic process GO:0044236 34 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
sleep GO:0030431 2 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
positive regulation of organelle organization GO:0010638 195 0.013
segmentation GO:0035282 4 0.013

TLR1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.063
Human
nervous system disease DOID:863 431 0.063
Human
eye and adnexa disease DOID:1492 150 0.045
Human
cancer DOID:162 167 0.042
Human
disease of cellular proliferation DOID:14566 174 0.042
Human
eye disease DOID:5614 149 0.039
Human
organ system cancer DOID:0050686 164 0.034
Human
retinal disease DOID:5679 118 0.029
Human
disease of metabolism DOID:0014667 295 0.025
gastrointestinal system cancer DOID:3119 52 0.016
Human
inherited metabolic disorder DOID:655 242 0.014