Homo sapiens

35 known processes

CLNS1A

chloride channel, nucleotide-sensitive, 1A

(Aliases: CLCI,ICln,CLNS1B)

CLNS1A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
spliceosomal snrnp assembly GO:0000387 28 1.000
mrna splicing via spliceosome GO:0000398 89 0.997
mrna processing GO:0006397 133 0.996
ribonucleoprotein complex assembly GO:0022618 78 0.988
oocyte differentiation GO:0009994 2 0.982
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.970
ribonucleoprotein complex biogenesis GO:0022613 116 0.966
rna splicing via transesterification reactions GO:0000375 90 0.957
histone arginine methylation GO:0034969 6 0.953
ribonucleoprotein complex subunit organization GO:0071826 81 0.938
oocyte development GO:0048599 1 0.917
regulation of meiosis GO:0040020 3 0.913
oogenesis GO:0048477 2 0.900
regulation of meiotic cell cycle GO:0051445 4 0.886
cytoplasmic mrna processing body assembly GO:0033962 10 0.883
rna splicing GO:0008380 131 0.873
female gamete generation GO:0007292 2 0.863
secretion GO:0046903 254 0.848
mrna metabolic process GO:0016071 175 0.828
anterior posterior axis specification embryo GO:0008595 2 0.813
cellular macromolecular complex assembly GO:0034622 324 0.812
rna processing GO:0006396 255 0.784
secretion by cell GO:0032940 226 0.717
tripartite regional subdivision GO:0007351 2 0.703
vesicle mediated transport GO:0016192 371 0.555
Worm
anterior posterior axis specification GO:0009948 2 0.536
maturation of ssu rrna GO:0030490 3 0.521
blastoderm segmentation GO:0007350 2 0.484
segmentation GO:0035282 4 0.384
endocytosis GO:0006897 159 0.374
Worm
hair cycle GO:0042633 28 0.302
post embryonic development GO:0009791 2 0.300
Worm
cell development GO:0048468 328 0.293
enzyme linked receptor protein signaling pathway GO:0007167 303 0.283
stem cell differentiation GO:0048863 93 0.259
ribosomal small subunit biogenesis GO:0042274 13 0.239
generation of neurons GO:0048699 152 0.221
peripheral nervous system development GO:0007422 2 0.219
mitotic spindle organization GO:0007052 27 0.215
intracellular mrna localization GO:0008298 1 0.192
regulation of erk1 and erk2 cascade GO:0070372 99 0.192
molting cycle GO:0042303 28 0.150
negative regulation of cell proliferation GO:0008285 228 0.143
neurogenesis GO:0022008 169 0.141
nucleus organization GO:0006997 28 0.138
ras protein signal transduction GO:0007265 73 0.131
determination of adult lifespan GO:0008340 2 0.128
regulation of cell cycle process GO:0010564 266 0.127
negative regulation of developmental process GO:0051093 247 0.126
rrna metabolic process GO:0016072 40 0.125
negative regulation of locomotion GO:0040013 118 0.117
organelle fission GO:0048285 149 0.113
positive regulation of phosphorylation GO:0042327 394 0.111
regulation of cellular ketone metabolic process GO:0010565 50 0.110
digestion GO:0007586 22 0.109
reproductive structure development GO:0048608 55 0.109
mitotic cell cycle GO:0000278 326 0.108
positive regulation of mapk cascade GO:0043410 190 0.108
positive regulation of synaptic transmission GO:0050806 4 0.104
small molecule biosynthetic process GO:0044283 157 0.103
lipid metabolic process GO:0006629 381 0.100
developmental process involved in reproduction GO:0003006 66 0.093
cellular ketone metabolic process GO:0042180 80 0.091
meiotic nuclear division GO:0007126 10 0.089
response to transforming growth factor beta GO:0071559 94 0.089
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.086
peptidyl arginine omega n methylation GO:0035247 4 0.085
synaptic transmission cholinergic GO:0007271 2 0.079
actin filament based process GO:0030029 224 0.078
regulation of lipid metabolic process GO:0019216 96 0.076
rrna processing GO:0006364 35 0.076
organic acid biosynthetic process GO:0016053 97 0.074
organelle assembly GO:0070925 176 0.072
nervous system development GO:0007399 293 0.071
small gtpase mediated signal transduction GO:0007264 78 0.069
regulation of mitotic cell cycle GO:0007346 189 0.068
cellular lipid metabolic process GO:0044255 303 0.068
alternative mrna splicing via spliceosome GO:0000380 27 0.067
regulation of cell cycle GO:0051726 393 0.066
multicellular organism reproduction GO:0032504 42 0.064
central nervous system development GO:0007417 123 0.064
cellular component morphogenesis GO:0032989 314 0.061
regulation of cell motility GO:2000145 299 0.060
ubiquitin dependent protein catabolic process GO:0006511 206 0.060
endothelial cell activation GO:0042118 3 0.057
single organism reproductive process GO:0044702 98 0.056
meiotic cell cycle GO:0051321 13 0.056
postsynaptic membrane organization GO:0001941 2 0.055
receptor mediated endocytosis GO:0006898 84 0.054
Worm
negative regulation of epithelial cell proliferation GO:0050680 48 0.052
protein localization to membrane GO:0072657 160 0.051
lipid biosynthetic process GO:0008610 177 0.051
locomotory behavior GO:0007626 1 0.051
amine metabolic process GO:0009308 44 0.050
multi organism reproductive process GO:0044703 54 0.049
multicellular organismal reproductive process GO:0048609 40 0.047
regulation of cellular response to growth factor stimulus GO:0090287 76 0.047
ncrna metabolic process GO:0034660 108 0.047
cellular response to growth factor stimulus GO:0071363 197 0.047
sexual reproduction GO:0019953 37 0.047
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.044
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.043
macromolecule methylation GO:0043414 97 0.043
cellular macromolecule catabolic process GO:0044265 380 0.043
monocarboxylic acid metabolic process GO:0032787 185 0.042
spindle organization GO:0007051 53 0.042
stem cell development GO:0048864 69 0.042
cell projection organization GO:0030030 252 0.041
regeneration GO:0031099 4 0.040
neuron differentiation GO:0030182 138 0.040
microtubule cytoskeleton organization GO:0000226 176 0.039
erk1 and erk2 cascade GO:0070371 104 0.039
modification dependent protein catabolic process GO:0019941 209 0.039
mapk cascade GO:0000165 288 0.038
protein oligomerization GO:0051259 173 0.038
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.038
multicellular organismal aging GO:0010259 3 0.038
regulation of locomotion GO:0040012 329 0.038
regulation of mapk cascade GO:0043408 262 0.037
gene silencing by rna GO:0031047 26 0.036
nuclear division GO:0000280 128 0.036
microtubule based process GO:0007017 210 0.036
signal transduction by phosphorylation GO:0023014 297 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
response to growth factor GO:0070848 205 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.034
negative regulation of cell migration GO:0030336 102 0.034
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.034
cell cycle phase transition GO:0044770 173 0.034
cell morphogenesis involved in differentiation GO:0000904 144 0.034
negative regulation of cell motility GO:2000146 104 0.033
developmental maturation GO:0021700 28 0.033
spermatid development GO:0007286 4 0.033
regulation of cell migration GO:0030334 289 0.033
immune response activating signal transduction GO:0002757 90 0.033
protein catabolic process GO:0030163 325 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
anterior posterior pattern specification GO:0009952 9 0.032
spliceosomal complex assembly GO:0000245 17 0.032
cell morphogenesis GO:0000902 296 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.031
embryo development GO:0009790 123 0.031
Worm
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
organophosphate biosynthetic process GO:0090407 163 0.030
fatty acid biosynthetic process GO:0006633 46 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
regulation of multi organism process GO:0043900 157 0.029
gonad development GO:0008406 34 0.029
regulation of response to dna damage stimulus GO:2001020 94 0.029
regulation of cellular response to stress GO:0080135 244 0.028
endomembrane system organization GO:0010256 196 0.028
mitotic cell cycle phase transition GO:0044772 162 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.028
regionalization GO:0003002 29 0.028
neuron development GO:0048666 113 0.027
growth GO:0040007 202 0.027
negative regulation of protein modification process GO:0031400 200 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
ribosome biogenesis GO:0042254 48 0.026
regulation of small gtpase mediated signal transduction GO:0051056 156 0.026
cellular amine metabolic process GO:0044106 41 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
regulation of cell division GO:0051302 116 0.024
positive regulation of cell cycle GO:0045787 140 0.024
embryo development ending in birth or egg hatching GO:0009792 34 0.024
Worm
embryonic axis specification GO:0000578 5 0.024
regulation of cell cycle phase transition GO:1901987 126 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.023
negative regulation of epithelial cell migration GO:0010633 38 0.023
intracellular receptor signaling pathway GO:0030522 104 0.023
regulation of epithelial cell proliferation GO:0050678 113 0.023
cellular component assembly involved in morphogenesis GO:0010927 73 0.023
positive regulation of transport GO:0051050 336 0.023
negative regulation of signal transduction by p53 class mediator GO:1901797 15 0.023
cellular response to nitrogen compound GO:1901699 144 0.023
cellular response to endogenous stimulus GO:0071495 336 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.022
regulation of ras protein signal transduction GO:0046578 155 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.021
cell division GO:0051301 168 0.021
viral life cycle GO:0019058 132 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
protein deubiquitination GO:0016579 79 0.020
protein processing GO:0016485 226 0.020
adult locomotory behavior GO:0008344 1 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
regulation of oocyte development GO:0060281 1 0.020
mitotic cell cycle process GO:1903047 286 0.019
mitotic nuclear division GO:0007067 119 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.019
negative regulation of response to dna damage stimulus GO:2001021 33 0.019
regulation of cell cycle g1 s phase transition GO:1902806 42 0.019
gmp metabolic process GO:0046037 4 0.019
spermatid differentiation GO:0048515 4 0.018
cellular response to sterol GO:0036315 7 0.018
carbohydrate metabolic process GO:0005975 207 0.018
regulation of cellular component movement GO:0051270 334 0.018
single organism membrane organization GO:0044802 268 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
ribose phosphate biosynthetic process GO:0046390 82 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
chromatin assembly or disassembly GO:0006333 78 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
protein alkylation GO:0008213 74 0.017
gamete generation GO:0007276 25 0.017
ameboidal type cell migration GO:0001667 135 0.017
response to ketone GO:1901654 19 0.016
glycerolipid metabolic process GO:0046486 107 0.016
rna catabolic process GO:0006401 71 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
cellular protein catabolic process GO:0044257 261 0.016
protein import into mitochondrial inner membrane GO:0045039 3 0.016
regulation of protein ubiquitination GO:0031396 95 0.016
negative regulation of cell cycle GO:0045786 193 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.015
reproduction GO:0000003 63 0.015
Worm
nitrogen compound transport GO:0071705 191 0.015
myosin filament organization GO:0031033 2 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
membrane organization GO:0061024 292 0.015
response to wounding GO:0009611 168 0.015
sensory perception of pain GO:0019233 4 0.015
fatty acid metabolic process GO:0006631 115 0.015
axis specification GO:0009798 12 0.014
response to decreased oxygen levels GO:0036293 96 0.014
leukocyte migration GO:0050900 107 0.014
negative regulation of protein processing GO:0010955 142 0.014
negative regulation of cellular component movement GO:0051271 106 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.014
nucleobase containing compound transport GO:0015931 51 0.014
response to organic cyclic compound GO:0014070 204 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.014
myosin filament assembly GO:0031034 2 0.014
pattern specification process GO:0007389 43 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
unsaturated fatty acid metabolic process GO:0033559 37 0.013
pathway restricted smad protein phosphorylation GO:0060389 38 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
chromatin modification GO:0016568 298 0.013
cell part morphogenesis GO:0032990 137 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
regulation of cell development GO:0060284 161 0.013
chromatin organization GO:0006325 351 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
negative regulation of protein metabolic process GO:0051248 391 0.012
ncrna processing GO:0034470 83 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
positive regulation of immune response GO:0050778 159 0.012
reproductive system development GO:0061458 56 0.012
response to axon injury GO:0048678 1 0.012
circulatory system development GO:0072359 262 0.012
regulation of protein binding GO:0043393 66 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
embryonic pattern specification GO:0009880 5 0.012
single fertilization GO:0007338 11 0.012
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.012
sex differentiation GO:0007548 45 0.012
regulation of cytokine production GO:0001817 232 0.012
maturation of lsu rrna GO:0000470 3 0.012
reproductive process GO:0022414 106 0.011
heart development GO:0007507 95 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
monocarboxylic acid biosynthetic process GO:0072330 67 0.011
methylation GO:0032259 106 0.011
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.011
oxidation reduction process GO:0055114 396 0.011
response to oxygen containing compound GO:1901700 369 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
neuromuscular junction development GO:0007528 3 0.011
taxis GO:0042330 157 0.011
nuclear transcribed mrna catabolic process GO:0000956 48 0.011
positive regulation of erbb signaling pathway GO:1901186 11 0.011
lung alveolus development GO:0048286 4 0.011
protein maturation GO:0051604 233 0.011
purine containing compound biosynthetic process GO:0072522 88 0.010
posttranscriptional gene silencing GO:0016441 25 0.010
establishment of nucleus localization GO:0040023 1 0.010
muscle cell differentiation GO:0042692 63 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
translational initiation GO:0006413 48 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010
epithelium migration GO:0090132 119 0.010
protein methylation GO:0006479 74 0.010
neuron projection development GO:0031175 106 0.010
positive regulation of cytoplasmic transport GO:1903651 82 0.010
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.010
axon development GO:0061564 34 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
immune response GO:0006955 307 0.010
translation GO:0006412 132 0.010
hematopoietic stem cell differentiation GO:0060218 4 0.010

CLNS1A disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.267
neurodegenerative disease DOID:1289 102 0.267
nervous system disease DOID:863 431 0.267
cancer DOID:162 167 0.037
disease of cellular proliferation DOID:14566 174 0.037
organ system cancer DOID:0050686 164 0.037
disease of metabolism DOID:0014667 295 0.029
immune system disease DOID:2914 155 0.013
bone marrow disease DOID:4961 31 0.013
hematopoietic system disease DOID:74 100 0.013