Homo sapiens

0 known processes

SMCHD1

structural maintenance of chromosomes flexible hinge domain containing 1

(Aliases: KIAA0650,DKFZp686O0631)

SMCHD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 50 0.207
cellular macromolecular complex assembly GO:0034622 324 0.170
oogenesis GO:0048477 2 0.169
female gamete generation GO:0007292 2 0.155
purine ribonucleoside metabolic process GO:0046128 437 0.133
cellular amine metabolic process GO:0044106 41 0.107
cellular amino acid metabolic process GO:0006520 116 0.103
positive regulation of cellular amine metabolic process GO:0033240 7 0.102
cellular ketone metabolic process GO:0042180 80 0.099
post embryonic development GO:0009791 2 0.088
purine containing compound catabolic process GO:0072523 411 0.087
amine metabolic process GO:0009308 44 0.083
dna conformation change GO:0071103 113 0.080
nervous system development GO:0007399 293 0.078
histone modification GO:0016570 251 0.072
purine ribonucleoside catabolic process GO:0046130 398 0.071
cell development GO:0048468 328 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
regulation of cell cycle GO:0051726 393 0.066
nucleoside monophosphate metabolic process GO:0009123 191 0.066
ribonucleoside triphosphate catabolic process GO:0009203 391 0.064
chromatin organization GO:0006325 351 0.064
regulation of cellular amino acid metabolic process GO:0006521 6 0.063
nucleoside catabolic process GO:0009164 408 0.062
actin filament based process GO:0030029 224 0.060
ribonucleoside catabolic process GO:0042454 406 0.058
chromatin modification GO:0016568 298 0.057
purine nucleoside monophosphate catabolic process GO:0009128 158 0.056
atp catabolic process GO:0006200 157 0.056
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.055
negative regulation of developmental process GO:0051093 247 0.054
negative regulation of protein metabolic process GO:0051248 391 0.053
microtubule cytoskeleton organization GO:0000226 176 0.052
cell projection organization GO:0030030 252 0.051
generation of neurons GO:0048699 152 0.050
cellular response to endogenous stimulus GO:0071495 336 0.050
positive regulation of cellular component organization GO:0051130 376 0.049
neuron projection development GO:0031175 106 0.048
cellular protein complex assembly GO:0043623 188 0.048
glycosyl compound catabolic process GO:1901658 413 0.047
forelimb morphogenesis GO:0035136 4 0.047
covalent chromatin modification GO:0016569 254 0.047
purine nucleoside catabolic process GO:0006152 398 0.047
regulation of cellular component biogenesis GO:0044087 281 0.046
cytoplasmic transport GO:0016482 379 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.045
ribonucleoside monophosphate metabolic process GO:0009161 187 0.045
mitotic cell cycle GO:0000278 326 0.045
ribonucleoside monophosphate catabolic process GO:0009158 158 0.044
regulation of cellular amine metabolic process GO:0033238 11 0.044
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
cell morphogenesis GO:0000902 296 0.043
organophosphate catabolic process GO:0046434 430 0.043
centrosome organization GO:0051297 58 0.043
atp metabolic process GO:0046034 176 0.043
ribonucleoside triphosphate metabolic process GO:0009199 412 0.042
cellular response to dna damage stimulus GO:0006974 379 0.042
purine nucleotide catabolic process GO:0006195 405 0.041
mitotic nuclear division GO:0007067 119 0.041
microtubule organizing center organization GO:0031023 62 0.041
microtubule based process GO:0007017 210 0.041
neurogenesis GO:0022008 169 0.040
positive regulation of organelle organization GO:0010638 195 0.040
multicellular organismal aging GO:0010259 3 0.040
protein localization to organelle GO:0033365 280 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.038
purine ribonucleotide catabolic process GO:0009154 404 0.037
somatic stem cell division GO:0048103 1 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.035
nucleocytoplasmic transport GO:0006913 176 0.035
regulation of protein complex assembly GO:0043254 147 0.035
cellular component morphogenesis GO:0032989 314 0.035
single organism cellular localization GO:1902580 332 0.035
positive regulation of protein phosphorylation GO:0001934 313 0.034
nucleotide catabolic process GO:0009166 408 0.034
regulation of chromosome organization GO:0033044 103 0.034
neuron development GO:0048666 113 0.033
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.033
dephosphorylation GO:0016311 209 0.032
determination of adult lifespan GO:0008340 2 0.032
stem cell development GO:0048864 69 0.031
ribonucleoprotein complex subunit organization GO:0071826 81 0.031
stem cell division GO:0017145 2 0.031
regulation of viral process GO:0050792 103 0.031
chromatin assembly GO:0031497 61 0.031
neuroblast proliferation GO:0007405 4 0.031
dna templated transcription initiation GO:0006352 35 0.031
nuclear division GO:0000280 128 0.030
chromatin assembly or disassembly GO:0006333 78 0.030
oocyte development GO:0048599 1 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
neuron differentiation GO:0030182 138 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
positive regulation of phosphorylation GO:0042327 394 0.029
endomembrane system organization GO:0010256 196 0.029
ribonucleotide catabolic process GO:0009261 405 0.028
peptidyl serine phosphorylation GO:0018105 101 0.028
nitrogen compound transport GO:0071705 191 0.028
oocyte differentiation GO:0009994 2 0.028
vesicle mediated transport GO:0016192 371 0.028
regulation of cell differentiation GO:0045595 393 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
nuclear transport GO:0051169 179 0.027
epithelium development GO:0060429 227 0.027
actin cytoskeleton organization GO:0030036 207 0.027
response to growth factor GO:0070848 205 0.026
protein deubiquitination GO:0016579 79 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
negative regulation of multicellular organismal process GO:0051241 317 0.026
organelle fission GO:0048285 149 0.026
meiotic chromosome segregation GO:0045132 4 0.026
positive regulation of apoptotic process GO:0043065 246 0.025
regulation of cell division GO:0051302 116 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
mitotic cell cycle process GO:1903047 286 0.025
cell division GO:0051301 168 0.025
viral process GO:0016032 146 0.025
response to abiotic stimulus GO:0009628 336 0.025
regulation of nucleocytoplasmic transport GO:0046822 98 0.025
skeletal system development GO:0001501 79 0.024
nuclear export GO:0051168 69 0.024
regulation of chromatin modification GO:1903308 51 0.024
translation GO:0006412 132 0.024
embryo development GO:0009790 123 0.024
cellular response to oxygen containing compound GO:1901701 276 0.023
macromolecule methylation GO:0043414 97 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
regulation of cell cycle process GO:0010564 266 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
central nervous system development GO:0007417 123 0.022
negative regulation of cell differentiation GO:0045596 171 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
regulation of neural precursor cell proliferation GO:2000177 4 0.021
regulation of intracellular transport GO:0032386 195 0.021
regulation of cell motility GO:2000145 299 0.021
regulation of locomotion GO:0040012 329 0.021
regulation of transferase activity GO:0051338 355 0.021
chemotaxis GO:0006935 157 0.021
cellular protein catabolic process GO:0044257 261 0.021
protein dna complex subunit organization GO:0071824 80 0.021
protein localization to nucleus GO:0034504 136 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
maintenance of location GO:0051235 112 0.020
regulation of response to external stimulus GO:0032101 222 0.020
system process GO:0003008 349 0.020
stem cell differentiation GO:0048863 93 0.020
regulation of multi organism process GO:0043900 157 0.020
response to other organism GO:0051707 261 0.020
sister chromatid segregation GO:0000819 54 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
negative regulation of protein modification process GO:0031400 200 0.020
regulation of proteolysis GO:0030162 293 0.020
organelle assembly GO:0070925 176 0.019
negative regulation of transport GO:0051051 176 0.019
response to organonitrogen compound GO:0010243 156 0.019
dna packaging GO:0006323 77 0.019
chromatin remodeling GO:0006338 55 0.019
interspecies interaction between organisms GO:0044419 156 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
protein modification by small protein removal GO:0070646 92 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
positive regulation of developmental process GO:0051094 314 0.019
immune response GO:0006955 307 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of immune response GO:0050776 201 0.018
memory GO:0007613 3 0.018
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.018
cell adhesion GO:0007155 325 0.018
protein autophosphorylation GO:0046777 123 0.018
mrna processing GO:0006397 133 0.018
response to nitrogen compound GO:1901698 184 0.018
response to oxygen containing compound GO:1901700 369 0.018
biological adhesion GO:0022610 331 0.018
negative regulation of cellular component organization GO:0051129 235 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
neurological system process GO:0050877 163 0.017
rna processing GO:0006396 255 0.017
sensory perception GO:0007600 103 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
mitotic sister chromatid segregation GO:0000070 53 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
endocytosis GO:0006897 159 0.017
histone exchange GO:0043486 3 0.017
protein targeting GO:0006605 187 0.017
regulation of transcription by chromatin organization GO:0034401 1 0.017
cell part morphogenesis GO:0032990 137 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.016
regulation of chromatin organization GO:1902275 56 0.016
regulation of phosphatase activity GO:0010921 81 0.016
epithelial cell differentiation GO:0030855 141 0.016
response to tumor necrosis factor GO:0034612 76 0.016
tube development GO:0035295 125 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
digestive system development GO:0055123 75 0.016
positive regulation of cell death GO:0010942 263 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
negative regulation of chromosome organization GO:2001251 48 0.016
cellular macromolecule catabolic process GO:0044265 380 0.015
protein catabolic process GO:0030163 325 0.015
secretion by cell GO:0032940 226 0.015
peripheral nervous system development GO:0007422 2 0.015
rna splicing GO:0008380 131 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
positive regulation of viral process GO:0048524 37 0.015
reproductive process GO:0022414 106 0.015
modulation by host of viral process GO:0044788 3 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
positive regulation of transferase activity GO:0051347 227 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
cell growth GO:0016049 160 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
defense response to fungus GO:0050832 4 0.015
wnt signaling pathway GO:0016055 156 0.015
regulation of cellular component movement GO:0051270 334 0.015
spermatid development GO:0007286 4 0.014
ameboidal type cell migration GO:0001667 135 0.014
protein maturation GO:0051604 233 0.014
leukocyte activation GO:0045321 164 0.014
double strand break repair GO:0006302 101 0.014
response to transforming growth factor beta GO:0071559 94 0.014
multi organism cellular process GO:0044764 156 0.014
single organism reproductive process GO:0044702 98 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
positive regulation of multi organism process GO:0043902 56 0.014
regulation of dephosphorylation GO:0035303 96 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
cell projection morphogenesis GO:0048858 129 0.014
intracellular protein transport GO:0006886 270 0.014
positive regulation of immune system process GO:0002684 283 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
response to external biotic stimulus GO:0043207 261 0.014
dna repair GO:0006281 198 0.014
regeneration GO:0031099 4 0.013
segmentation GO:0035282 4 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
head development GO:0060322 108 0.013
somitogenesis GO:0001756 2 0.013
negative regulation of cell death GO:0060548 345 0.013
regulation of meiosis GO:0040020 3 0.013
positive regulation of cell development GO:0010720 92 0.013
lymphocyte activation GO:0046649 133 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.013
positive regulation of intracellular protein transport GO:0090316 76 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
apoptotic signaling pathway GO:0097190 268 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
response to fungus GO:0009620 4 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
response to hormone GO:0009725 175 0.013
viral life cycle GO:0019058 132 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
peptidyl serine modification GO:0018209 106 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
embryonic viscerocranium morphogenesis GO:0048703 1 0.012
regulation of peptidyl serine phosphorylation GO:0033135 50 0.012
histone ubiquitination GO:0016574 31 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
digestive tract development GO:0048565 75 0.012
response to bacterium GO:0009617 144 0.012
protein dna complex assembly GO:0065004 64 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
defense response GO:0006952 315 0.012
regulation of protein kinase activity GO:0045859 289 0.012
spindle elongation GO:0051231 4 0.012
positive regulation of transport GO:0051050 336 0.012
response to biotic stimulus GO:0009607 276 0.012
methylation GO:0032259 106 0.012
embryonic placenta development GO:0001892 1 0.012
cytokinesis GO:0000910 96 0.012
nucleic acid transport GO:0050657 39 0.012
single organism membrane organization GO:0044802 268 0.012
taxis GO:0042330 157 0.012
regulation of dna metabolic process GO:0051052 153 0.012
positive regulation of kinase activity GO:0033674 204 0.012
behavioral response to ethanol GO:0048149 2 0.012
embryonic camera type eye development GO:0031076 2 0.012
negative regulation of protein maturation GO:1903318 142 0.012
protein ubiquitination GO:0016567 314 0.012
response to wounding GO:0009611 168 0.012
establishment of rna localization GO:0051236 39 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
regulation of growth GO:0040008 165 0.011
negative regulation of organelle organization GO:0010639 126 0.011
regulation of protein localization GO:0032880 296 0.011
growth GO:0040007 202 0.011
negative regulation of transferase activity GO:0051348 124 0.011
rhythmic behavior GO:0007622 2 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
epithelial cell migration GO:0010631 119 0.011
long term memory GO:0007616 2 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
regulation of cytokine production GO:0001817 232 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
positive regulation of proteolysis GO:0045862 142 0.011
protein processing GO:0016485 226 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
regulation of protein processing GO:0070613 150 0.011
chemical homeostasis GO:0048878 306 0.011
embryonic forelimb morphogenesis GO:0035115 4 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
membrane organization GO:0061024 292 0.011
nucleosome organization GO:0034728 66 0.011
positive regulation of cell division GO:0051781 59 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
mapk cascade GO:0000165 288 0.011
negative regulation of immune system process GO:0002683 136 0.011
regulation of rna splicing GO:0043484 62 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
regulation of defense response GO:0031347 154 0.010
neuromuscular junction development GO:0007528 3 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
single organism cell adhesion GO:0098602 179 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
centrosome cycle GO:0007098 32 0.010
regulation of cellular response to stress GO:0080135 244 0.010
carbohydrate metabolic process GO:0005975 207 0.010
positive regulation of immune response GO:0050778 159 0.010
axis elongation GO:0003401 4 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
muscle structure development GO:0061061 98 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
regulation of protein transport GO:0051223 213 0.010

SMCHD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.033
eye and adnexa disease DOID:1492 150 0.033
nervous system disease DOID:863 431 0.033
central nervous system disease DOID:331 186 0.030
eye disease DOID:5614 149 0.029
neurodegenerative disease DOID:1289 102 0.017