Homo sapiens

29 known processes

PLOD1

procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1

(Aliases: PLOD,LLH,LH1,LH,FLJ42041)

PLOD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.612
Rat
carbohydrate metabolic process GO:0005975 207 0.564
protein o linked glycosylation via serine GO:0018242 3 0.464
single organism carbohydrate metabolic process GO:0044723 193 0.351
cellular amino acid metabolic process GO:0006520 116 0.175
skeletal system development GO:0001501 79 0.173
post embryonic development GO:0009791 2 0.158
response to abiotic stimulus GO:0009628 336 0.126
protein glycosylation GO:0006486 62 0.122
monocarboxylic acid metabolic process GO:0032787 185 0.120
determination of adult lifespan GO:0008340 2 0.118
protein folding GO:0006457 38 0.112
motor neuron axon guidance GO:0008045 2 0.109
multicellular organismal aging GO:0010259 3 0.103
cellular amine metabolic process GO:0044106 41 0.098
carbohydrate catabolic process GO:0016052 36 0.094
carbohydrate derivative biosynthetic process GO:1901137 207 0.093
biological adhesion GO:0022610 331 0.088
Human
protein hydroxylation GO:0018126 9 0.085
Rat
system process GO:0003008 349 0.074
peptidyl proline modification GO:0018208 15 0.071
positive regulation of cell proliferation GO:0008284 301 0.071
cardiovascular system development GO:0072358 262 0.071
multicellular organismal metabolic process GO:0044236 34 0.068
cellular carbohydrate metabolic process GO:0044262 84 0.068
regulation of cellular amine metabolic process GO:0033238 11 0.066
positive regulation of developmental process GO:0051094 314 0.064
response to hypoxia GO:0001666 96 0.061
extracellular structure organization GO:0043062 41 0.061
vesicle mediated transport GO:0016192 371 0.060
locomotory behavior GO:0007626 1 0.058
collagen metabolic process GO:0032963 28 0.057
cell morphogenesis GO:0000902 296 0.057
response to oxygen containing compound GO:1901700 369 0.055
epithelium development GO:0060429 227 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
organonitrogen compound biosynthetic process GO:1901566 200 0.053
cellular ketone metabolic process GO:0042180 80 0.053
azole transport GO:0045117 4 0.052
peptidyl tyrosine modification GO:0018212 170 0.052
regulation of cellular ketone metabolic process GO:0010565 50 0.048
cellular modified amino acid metabolic process GO:0006575 64 0.047
actin cytoskeleton organization GO:0030036 207 0.046
circulatory system development GO:0072359 262 0.046
cell adhesion GO:0007155 325 0.045
Human
protein stabilization GO:0050821 64 0.045
response to decreased oxygen levels GO:0036293 96 0.044
multicellular organismal macromolecule metabolic process GO:0044259 29 0.043
extracellular matrix organization GO:0030198 41 0.041
cellular component morphogenesis GO:0032989 314 0.041
posttranscriptional regulation of gene expression GO:0010608 213 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
generation of precursor metabolites and energy GO:0006091 68 0.040
positive regulation of cell motility GO:2000147 177 0.040
protein catabolic process GO:0030163 325 0.040
actin filament based process GO:0030029 224 0.039
growth GO:0040007 202 0.038
Fly
basement membrane organization GO:0071711 3 0.036
4 hydroxyproline metabolic process GO:0019471 5 0.035
regulation of response to external stimulus GO:0032101 222 0.035
ameboidal type cell migration GO:0001667 135 0.035
cell morphogenesis involved in differentiation GO:0000904 144 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
collagen fibril organization GO:0030199 10 0.034
secretion GO:0046903 254 0.034
glycoprotein biosynthetic process GO:0009101 91 0.034
amine metabolic process GO:0009308 44 0.034
regulation of locomotion GO:0040012 329 0.033
vasodilation GO:0042311 4 0.032
single organism carbohydrate catabolic process GO:0044724 33 0.032
alpha amino acid metabolic process GO:1901605 72 0.032
negative regulation of protein metabolic process GO:0051248 391 0.031
epidermis development GO:0008544 59 0.031
response to wounding GO:0009611 168 0.030
regulation of growth GO:0040008 165 0.030
regulation of cell migration GO:0030334 289 0.030
cell development GO:0048468 328 0.030
Fly
organophosphate biosynthetic process GO:0090407 163 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.029
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
epidermis morphogenesis GO:0048730 3 0.028
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
regulation of protein localization GO:0032880 296 0.027
cellular polysaccharide metabolic process GO:0044264 27 0.027
regulation of cell cycle GO:0051726 393 0.027
glycoprotein metabolic process GO:0009100 110 0.027
regulation of cellular response to stress GO:0080135 244 0.027
transmembrane transport GO:0055085 399 0.027
regulation of mapk cascade GO:0043408 262 0.026
chemotaxis GO:0006935 157 0.026
neural crest cell development GO:0014032 3 0.026
stem cell development GO:0048864 69 0.026
secretion by cell GO:0032940 226 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
mapk cascade GO:0000165 288 0.025
taxis GO:0042330 157 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
regulation of cellular component movement GO:0051270 334 0.025
bone development GO:0060348 26 0.025
cell projection organization GO:0030030 252 0.025
regulation of response to wounding GO:1903034 101 0.025
negative regulation of locomotion GO:0040013 118 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
neurological system process GO:0050877 163 0.024
positive regulation of locomotion GO:0040017 186 0.024
positive regulation of transport GO:0051050 336 0.024
hindbrain development GO:0030902 3 0.024
response to oxygen levels GO:0070482 100 0.024
apoptotic signaling pathway GO:0097190 268 0.024
regulation of protein stability GO:0031647 87 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
response to hormone GO:0009725 175 0.023
Rat
cell projection assembly GO:0030031 126 0.023
peptidyl glutamic acid modification GO:0018200 4 0.023
positive regulation of hydrolase activity GO:0051345 331 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
angiogenesis GO:0001525 147 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
vitamin transmembrane transport GO:0035461 4 0.022
ossification GO:0001503 121 0.022
regulation of meiotic cell cycle GO:0051445 4 0.021
cellular protein complex assembly GO:0043623 188 0.021
thiamine transmembrane transport GO:0071934 2 0.021
gtp metabolic process GO:0046039 239 0.021
mesenchyme development GO:0060485 59 0.021
regulation of secretion by cell GO:1903530 177 0.021
blood vessel morphogenesis GO:0048514 162 0.021
macromolecule glycosylation GO:0043413 63 0.020
chemical homeostasis GO:0048878 306 0.020
vitamin metabolic process GO:0006766 26 0.020
protein maturation GO:0051604 233 0.020
thiamine transport GO:0015888 3 0.020
negative regulation of cell migration GO:0030336 102 0.020
mesenchymal cell differentiation GO:0048762 52 0.020
segmentation GO:0035282 4 0.020
neurogenesis GO:0022008 169 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
nuclear transport GO:0051169 179 0.020
regulation of cell cycle process GO:0010564 266 0.019
cytoplasmic transport GO:0016482 379 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
aging GO:0007568 66 0.019
positive regulation of cell migration GO:0030335 172 0.019
cell part morphogenesis GO:0032990 137 0.019
wound healing GO:0042060 115 0.019
regulation of cell motility GO:2000145 299 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
epithelial cell differentiation GO:0030855 141 0.019
fat soluble vitamin metabolic process GO:0006775 19 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
memory GO:0007613 3 0.019
protein localization to organelle GO:0033365 280 0.018
monosaccharide metabolic process GO:0005996 74 0.018
cellular glucan metabolic process GO:0006073 22 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
nervous system development GO:0007399 293 0.018
neural crest cell migration GO:0001755 2 0.018
cell growth GO:0016049 160 0.018
endothelial cell migration GO:0043542 86 0.018
cellular protein catabolic process GO:0044257 261 0.018
ribonucleotide biosynthetic process GO:0009260 81 0.018
head development GO:0060322 108 0.018
regulation of cell growth GO:0001558 135 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
protein oligomerization GO:0051259 173 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
regulation of cell morphogenesis GO:0022604 153 0.017
purine containing compound biosynthetic process GO:0072522 88 0.017
neuron projection development GO:0031175 106 0.017
glycogen catabolic process GO:0005980 4 0.017
negative regulation of cell motility GO:2000146 104 0.017
organophosphate catabolic process GO:0046434 430 0.017
regulation of protein secretion GO:0050708 86 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
carbohydrate biosynthetic process GO:0016051 42 0.017
cellular response to external stimulus GO:0071496 111 0.017
negative regulation of cellular component movement GO:0051271 106 0.017
neuromuscular junction development GO:0007528 3 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
regulation of meiosis GO:0040020 3 0.016
embryo development GO:0009790 123 0.016
glycogen metabolic process GO:0005977 22 0.016
regulation of collagen catabolic process GO:0010710 3 0.016
cell death in response to oxidative stress GO:0036473 29 0.016
cell chemotaxis GO:0060326 112 0.016
response to lithium ion GO:0010226 2 0.016
response to growth factor GO:0070848 205 0.016
regulation of kinase activity GO:0043549 314 0.016
negative regulation of rho gtpase activity GO:0034259 4 0.016
response to radiation GO:0009314 151 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
hexose metabolic process GO:0019318 55 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
innate immune response GO:0045087 178 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
anterior posterior axis specification GO:0009948 2 0.015
regeneration GO:0031099 4 0.015
cerebellum development GO:0021549 2 0.015
glycerophospholipid metabolic process GO:0006650 84 0.015
cellular lipid metabolic process GO:0044255 303 0.015
negative regulation of developmental process GO:0051093 247 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
regulation of protein transport GO:0051223 213 0.015
osteoblast differentiation GO:0001649 92 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of hormone levels GO:0010817 125 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
positive regulation of epithelial cell proliferation GO:0050679 65 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
ion transmembrane transport GO:0034220 338 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
endocytosis GO:0006897 159 0.015
cellular response to oxygen levels GO:0071453 55 0.015
muscle cell cellular homeostasis GO:0046716 3 0.014
startle response GO:0001964 3 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
maintenance of location GO:0051235 112 0.014
response to unfolded protein GO:0006986 24 0.014
vasculature development GO:0001944 181 0.014
regulation of cell differentiation GO:0045595 393 0.014
muscle contraction GO:0006936 73 0.014
regulation of leukocyte migration GO:0002685 63 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
lipid catabolic process GO:0016042 84 0.014
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
positive regulation of kinase activity GO:0033674 204 0.014
neuron development GO:0048666 113 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.013
organ morphogenesis GO:0009887 147 0.013
pyruvate metabolic process GO:0006090 26 0.013
regulation of cell adhesion GO:0030155 166 0.013
negative regulation of catabolic process GO:0009895 104 0.013
cellular response to hypoxia GO:0071456 51 0.013
regulation of protein kinase activity GO:0045859 289 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.013
regulation of proteolysis GO:0030162 293 0.013
endochondral bone morphogenesis GO:0060350 3 0.013
salivary gland morphogenesis GO:0007435 4 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
polysaccharide metabolic process GO:0005976 33 0.013
response to axon injury GO:0048678 1 0.013
negative regulation of proteolysis GO:0045861 132 0.013
protein processing GO:0016485 226 0.013
striated muscle contraction GO:0006941 52 0.013
tissue regeneration GO:0042246 3 0.013
endodermal cell differentiation GO:0035987 31 0.013
sleep GO:0030431 2 0.013
somitogenesis GO:0001756 2 0.013
nitrogen compound transport GO:0071705 191 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
dna replication GO:0006260 116 0.013
purine containing compound catabolic process GO:0072523 411 0.012
positive regulation of transferase activity GO:0051347 227 0.012
response to biotic stimulus GO:0009607 276 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.012
response to uv GO:0009411 73 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
cell cycle arrest GO:0007050 71 0.012
positive regulation of behavior GO:0048520 60 0.012
defense response GO:0006952 315 0.012
regulation of cell development GO:0060284 161 0.012
rho protein signal transduction GO:0007266 26 0.012
myosin filament organization GO:0031033 2 0.012
positive regulation of catabolic process GO:0009896 310 0.012
associative learning GO:0008306 1 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
blastoderm segmentation GO:0007350 2 0.012
tube development GO:0035295 125 0.012
positive regulation of cell death GO:0010942 263 0.012
nuclear division GO:0000280 128 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
formation of primary germ layer GO:0001704 42 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
cell cycle phase transition GO:0044770 173 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
midgut development GO:0007494 1 0.012
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.012
aminoglycan metabolic process GO:0006022 39 0.012
cell projection morphogenesis GO:0048858 129 0.012
cellular amide metabolic process GO:0043603 69 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
energy reserve metabolic process GO:0006112 22 0.012
positive regulation of leukocyte chemotaxis GO:0002690 38 0.012
positive regulation of leukocyte migration GO:0002687 46 0.012
regulation of peptidase activity GO:0052547 180 0.012
protein n linked glycosylation GO:0006487 23 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
regulation of endocytosis GO:0030100 72 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
circulatory system process GO:0003013 113 0.012
regulation of transferase activity GO:0051338 355 0.012
membrane protein proteolysis GO:0033619 38 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
regulation of erk1 and erk2 cascade GO:0070372 99 0.012
renal system development GO:0072001 63 0.011
regulation of secretion GO:0051046 194 0.011
response to cytokine GO:0034097 232 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
response to topologically incorrect protein GO:0035966 29 0.011
central nervous system development GO:0007417 123 0.011
adult locomotory behavior GO:0008344 1 0.011
regulation of body fluid levels GO:0050878 99 0.011
lipid metabolic process GO:0006629 381 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
positive regulation of cell development GO:0010720 92 0.011
regulation of camp metabolic process GO:0030814 52 0.011
organelle fission GO:0048285 149 0.011
regulation of axon guidance GO:1902667 3 0.011
female gamete generation GO:0007292 2 0.011
Fly
regulation of nuclear division GO:0051783 65 0.011
myosin filament assembly GO:0031034 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 0.011
negative regulation of cell death GO:0060548 345 0.011
heart development GO:0007507 95 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.011
epithelial cell proliferation GO:0050673 128 0.011
single organism membrane organization GO:0044802 268 0.011
post embryonic organ development GO:0048569 1 0.011
regulation of camp biosynthetic process GO:0030817 45 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
ion homeostasis GO:0050801 230 0.011
cell substrate adhesion GO:0031589 132 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
camp metabolic process GO:0046058 61 0.011
protein homooligomerization GO:0051260 100 0.011
regulation of nervous system development GO:0051960 88 0.011
response to endoplasmic reticulum stress GO:0034976 49 0.011
neuron projection regeneration GO:0031102 1 0.011
glycerolipid biosynthetic process GO:0045017 51 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
negative regulation of transport GO:0051051 176 0.010
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
cell substrate junction assembly GO:0007044 35 0.010
protein secretion GO:0009306 98 0.010
extrinsic apoptotic signaling pathway GO:0097191 119 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
pericardium development GO:0060039 2 0.010
regulation of chemotaxis GO:0050920 74 0.010
response to lipid GO:0033993 206 0.010
positive regulation of angiogenesis GO:0045766 51 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
regulation of intracellular transport GO:0032386 195 0.010
regulation of cell division GO:0051302 116 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010

PLOD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 35 0.452
osteogenesis imperfecta DOID:12347 13 0.452
bone development disease DOID:0080006 55 0.452
bone disease DOID:0080001 88 0.452
musculoskeletal system disease DOID:17 223 0.452
connective tissue disease DOID:65 109 0.452
disease of metabolism DOID:0014667 295 0.084
inherited metabolic disorder DOID:655 242 0.084
central nervous system disease DOID:331 186 0.064
nervous system disease DOID:863 431 0.064
disease of mental health DOID:150 70 0.029
neurodegenerative disease DOID:1289 102 0.027
disease of cellular proliferation DOID:14566 174 0.025
immune system disease DOID:2914 155 0.020
sensory system disease DOID:0050155 203 0.019
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
retinal disease DOID:5679 118 0.017
cancer DOID:162 167 0.016
organ system cancer DOID:0050686 164 0.016
carbohydrate metabolic disorder DOID:2978 55 0.015
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
myopathy DOID:423 104 0.010
collagen disease DOID:854 9 0.002
ehlers danlos syndrome DOID:13359 9 0.001