Homo sapiens

0 known processes

DNASE2

deoxyribonuclease II, lysosomal

(Aliases: DNL2,DNL,DNASE2A)

DNASE2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.067
amine metabolic process GO:0009308 44 0.064
lipid metabolic process GO:0006629 381 0.061
multicellular organismal aging GO:0010259 3 0.059
cellular lipid metabolic process GO:0044255 303 0.058
determination of adult lifespan GO:0008340 2 0.057
chemical homeostasis GO:0048878 306 0.055
cellular amino acid metabolic process GO:0006520 116 0.054
regulation of cellular ketone metabolic process GO:0010565 50 0.046
cellular ketone metabolic process GO:0042180 80 0.045
oxidation reduction process GO:0055114 396 0.043
post embryonic development GO:0009791 2 0.041
defense response GO:0006952 315 0.039
regulation of cellular amine metabolic process GO:0033238 11 0.037
cation transport GO:0006812 331 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.035
cellular macromolecule catabolic process GO:0044265 380 0.035
membrane organization GO:0061024 292 0.033
response to oxygen containing compound GO:1901700 369 0.032
epithelium development GO:0060429 227 0.032
immune response GO:0006955 307 0.032
positive regulation of cellular amine metabolic process GO:0033240 7 0.032
system process GO:0003008 349 0.032
transmembrane transport GO:0055085 399 0.031
metal ion transport GO:0030001 272 0.031
regulation of cytokine production GO:0001817 232 0.031
lipid biosynthetic process GO:0008610 177 0.030
anatomical structure homeostasis GO:0060249 100 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
protein maturation GO:0051604 233 0.029
neurological system process GO:0050877 163 0.029
response to abiotic stimulus GO:0009628 336 0.029
cytoplasmic transport GO:0016482 379 0.029
cell adhesion GO:0007155 325 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
biological adhesion GO:0022610 331 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
positive regulation of transport GO:0051050 336 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
positive regulation of cytokine production GO:0001819 167 0.027
cellular protein catabolic process GO:0044257 261 0.027
protein processing GO:0016485 226 0.026
protein catabolic process GO:0030163 325 0.026
multicellular organismal homeostasis GO:0048871 67 0.026
response to other organism GO:0051707 261 0.025
anion transport GO:0006820 161 0.025
positive regulation of immune system process GO:0002684 283 0.025
single organism carbohydrate metabolic process GO:0044723 193 0.025
segmentation GO:0035282 4 0.024
female gamete generation GO:0007292 2 0.024
single organism membrane organization GO:0044802 268 0.024
intracellular protein transport GO:0006886 270 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
regulation of transferase activity GO:0051338 355 0.024
carbohydrate metabolic process GO:0005975 207 0.024
secretion by cell GO:0032940 226 0.024
oogenesis GO:0048477 2 0.023
locomotory behavior GO:0007626 1 0.023
regeneration GO:0031099 4 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
response to biotic stimulus GO:0009607 276 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.023
innate immune response GO:0045087 178 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
regulation of protein localization GO:0032880 296 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
vesicle mediated transport GO:0016192 371 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
detection of chemical stimulus GO:0009593 55 0.022
cytokine production GO:0001816 247 0.022
organic acid biosynthetic process GO:0016053 97 0.022
regulation of kinase activity GO:0043549 314 0.022
response to external biotic stimulus GO:0043207 261 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
mapk cascade GO:0000165 288 0.021
ras protein signal transduction GO:0007265 73 0.021
response to lipid GO:0033993 206 0.021
blastoderm segmentation GO:0007350 2 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
regulation of cell differentiation GO:0045595 393 0.021
negative regulation of cell death GO:0060548 345 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
carboxylic acid biosynthetic process GO:0046394 97 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
neuromuscular junction development GO:0007528 3 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
monocarboxylic acid metabolic process GO:0032787 185 0.020
regulation of protein transport GO:0051223 213 0.020
regulation of hormone levels GO:0010817 125 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
cellular amide metabolic process GO:0043603 69 0.019
fatty acid metabolic process GO:0006631 115 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
memory GO:0007613 3 0.019
regulation of cellular response to stress GO:0080135 244 0.019
purine containing compound catabolic process GO:0072523 411 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
small molecule biosynthetic process GO:0044283 157 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
sulfur compound metabolic process GO:0006790 101 0.019
regulation of secretion GO:0051046 194 0.019
organophosphate catabolic process GO:0046434 430 0.019
sensory perception of bitter taste GO:0050913 28 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
nucleotide catabolic process GO:0009166 408 0.019
regulation of establishment of protein localization GO:0070201 242 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
lipid catabolic process GO:0016042 84 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
ion homeostasis GO:0050801 230 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
alcohol metabolic process GO:0006066 114 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
protein localization to organelle GO:0033365 280 0.018
regulation of cell cycle GO:0051726 393 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
response to bacterium GO:0009617 144 0.018
cation homeostasis GO:0055080 189 0.017
single organism cellular localization GO:1902580 332 0.017
secretion GO:0046903 254 0.017
regulation of protein kinase activity GO:0045859 289 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
dephosphorylation GO:0016311 209 0.017
protein ubiquitination GO:0016567 314 0.017
regulation of immune response GO:0050776 201 0.017
ion transmembrane transport GO:0034220 338 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
positive regulation of immune response GO:0050778 159 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
positive regulation of developmental process GO:0051094 314 0.017
regulation of defense response GO:0031347 154 0.017
organic anion transport GO:0015711 103 0.017
nitrogen compound transport GO:0071705 191 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
tissue regeneration GO:0042246 3 0.017
cellular homeostasis GO:0019725 196 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
hemopoiesis GO:0030097 180 0.016
positive regulation of kinase activity GO:0033674 204 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
anterior posterior axis specification GO:0009948 2 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
apoptotic signaling pathway GO:0097190 268 0.016
immune system development GO:0002520 195 0.016
cell morphogenesis GO:0000902 296 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
positive regulation of transferase activity GO:0051347 227 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
cation transmembrane transport GO:0098655 238 0.016
regulation of intracellular transport GO:0032386 195 0.016
adult locomotory behavior GO:0008344 1 0.016
cellular component morphogenesis GO:0032989 314 0.016
negative regulation of developmental process GO:0051093 247 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
vacuole organization GO:0007033 44 0.016
cell projection organization GO:0030030 252 0.016
phospholipid metabolic process GO:0006644 99 0.015
carboxylic acid catabolic process GO:0046395 71 0.015
spermatid differentiation GO:0048515 4 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
glycoprotein metabolic process GO:0009100 110 0.015
nucleoside catabolic process GO:0009164 408 0.015
hindbrain development GO:0030902 3 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
metencephalon development GO:0022037 2 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
nervous system development GO:0007399 293 0.015
response to hormone GO:0009725 175 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
response to organic cyclic compound GO:0014070 204 0.015
organelle assembly GO:0070925 176 0.015
microtubule based process GO:0007017 210 0.014
regulation of mapk cascade GO:0043408 262 0.014
regulation of secretion by cell GO:1903530 177 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
rhythmic behavior GO:0007622 2 0.014
cofactor metabolic process GO:0051186 87 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
cellular ion homeostasis GO:0006873 168 0.014
regulation of cell cycle process GO:0010564 266 0.014
cellular cation homeostasis GO:0030003 163 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
cell growth GO:0016049 160 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
response to nitrogen compound GO:1901698 184 0.014
growth GO:0040007 202 0.014
regulation of proteolysis GO:0030162 293 0.014
negative regulation of protein modification process GO:0031400 200 0.014
sensory perception GO:0007600 103 0.014
rho protein signal transduction GO:0007266 26 0.014
actin filament based process GO:0030029 224 0.014
cellular chemical homeostasis GO:0055082 180 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
oocyte development GO:0048599 1 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
antigen processing and presentation via mhc class ib GO:0002475 3 0.014
cellular response to external stimulus GO:0071496 111 0.014
peripheral nervous system development GO:0007422 2 0.014
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.014
response to cytokine GO:0034097 232 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
sensory perception of pain GO:0019233 4 0.014
regulation of immune effector process GO:0002697 91 0.014
protein targeting GO:0006605 187 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
mitotic cell cycle GO:0000278 326 0.013
cellular modified amino acid metabolic process GO:0006575 64 0.013
spermatid development GO:0007286 4 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
divalent inorganic cation transport GO:0072511 158 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
tissue homeostasis GO:0001894 63 0.013
calcium ion transport GO:0006816 147 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
protein oligomerization GO:0051259 173 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
positive regulation of catabolic process GO:0009896 310 0.013
cellular response to nutrient levels GO:0031669 69 0.013
positive regulation of defense response GO:0031349 87 0.013
mitotic cell cycle process GO:1903047 286 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
response to extracellular stimulus GO:0009991 85 0.013
oocyte differentiation GO:0009994 2 0.013
negative regulation of immune system process GO:0002683 136 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
regulation of ion transport GO:0043269 189 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
lipid localization GO:0010876 106 0.013
regulation of innate immune response GO:0045088 97 0.013
protein localization to membrane GO:0072657 160 0.013
maintenance of location GO:0051235 112 0.012
carboxylic acid transport GO:0046942 63 0.012
circulatory system development GO:0072359 262 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
prostate gland development GO:0030850 3 0.012
tripartite regional subdivision GO:0007351 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
tube closure GO:0060606 3 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
response to organonitrogen compound GO:0010243 156 0.012
nuclear transport GO:0051169 179 0.012
regulation of cellular component movement GO:0051270 334 0.012
membrane lipid metabolic process GO:0006643 53 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
regulation of protein maturation GO:1903317 150 0.012
sensory perception of taste GO:0050909 36 0.012
response to oxygen levels GO:0070482 100 0.012
cellular lipid catabolic process GO:0044242 65 0.012
negative regulation of transferase activity GO:0051348 124 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
long chain fatty acid metabolic process GO:0001676 30 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
compound eye development GO:0048749 1 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
cellular protein complex assembly GO:0043623 188 0.012
defense response to other organism GO:0098542 129 0.012
hormone metabolic process GO:0042445 61 0.012
cell cycle phase transition GO:0044770 173 0.012
atp metabolic process GO:0046034 176 0.012
divalent metal ion transport GO:0070838 152 0.012
cell development GO:0048468 328 0.012
response to inorganic substance GO:0010035 127 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
response to hypoxia GO:0001666 96 0.012
lymphocyte activation GO:0046649 133 0.012
positive regulation of synaptic transmission GO:0050806 4 0.011
epithelial cell proliferation GO:0050673 128 0.011
lipid transport GO:0006869 90 0.011
organic acid transport GO:0015849 65 0.011
regulation of cell activation GO:0050865 125 0.011
cerebellum development GO:0021549 2 0.011
positive regulation of protein transport GO:0051222 135 0.011
positive regulation of cell death GO:0010942 263 0.011
detection of stimulus GO:0051606 85 0.011
negative regulation of cell cycle GO:0045786 193 0.011
activation of immune response GO:0002253 114 0.011
vasodilation GO:0042311 4 0.011
positive regulation of innate immune response GO:0045089 79 0.011
monosaccharide metabolic process GO:0005996 74 0.011
regulation of homeostatic process GO:0032844 121 0.011
glycerolipid metabolic process GO:0046486 107 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
limbic system development GO:0021761 3 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
organic hydroxy compound transport GO:0015850 63 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
gtp metabolic process GO:0046039 239 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
cell projection assembly GO:0030031 126 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
rna interference GO:0016246 4 0.011
regulation of response to external stimulus GO:0032101 222 0.011
retina homeostasis GO:0001895 42 0.011
response to axon injury GO:0048678 1 0.011
associative learning GO:0008306 1 0.011
mitochondrion organization GO:0007005 156 0.011
sequestering of metal ion GO:0051238 24 0.011
endosomal transport GO:0016197 129 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
response to nutrient levels GO:0031667 81 0.011
mating GO:0007618 1 0.011
organic acid catabolic process GO:0016054 71 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of peptidase activity GO:0052547 180 0.011
regulation of dephosphorylation GO:0035303 96 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
endocytosis GO:0006897 159 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
inner ear morphogenesis GO:0042472 4 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
leukocyte mediated immunity GO:0002443 59 0.011
response to fungus GO:0009620 4 0.010
neural tube closure GO:0001843 3 0.010
regulation of cell growth GO:0001558 135 0.010
epithelial cell differentiation GO:0030855 141 0.010
immune effector process GO:0002252 159 0.010
cellular response to starvation GO:0009267 58 0.010
positive regulation of organelle organization GO:0010638 195 0.010
histone modification GO:0016570 251 0.010
cellular divalent inorganic cation homeostasis GO:0072503 128 0.010
response to growth factor GO:0070848 205 0.010
peptide metabolic process GO:0006518 51 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
positive regulation of regulatory t cell differentiation GO:0045591 3 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010
interspecies interaction between organisms GO:0044419 156 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
morphogenesis of a polarized epithelium GO:0001738 3 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
cell activation GO:0001775 213 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
response to decreased oxygen levels GO:0036293 96 0.010
negative regulation of proteolysis GO:0045861 132 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
autophagy GO:0006914 88 0.010
circadian behavior GO:0048512 2 0.010
regulation of cell migration GO:0030334 289 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
sphingolipid metabolic process GO:0006665 38 0.010
coenzyme metabolic process GO:0006732 65 0.010
regulation of dna metabolic process GO:0051052 153 0.010

DNASE2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.312
inherited metabolic disorder DOID:655 242 0.269
lysosomal storage disease DOID:3211 47 0.138
central nervous system disease DOID:331 186 0.075
nervous system disease DOID:863 431 0.075
lipid storage disease DOID:9455 28 0.038
musculoskeletal system disease DOID:17 223 0.031
neuronal ceroid lipofuscinosis DOID:14503 11 0.022
neurodegenerative disease DOID:1289 102 0.021
disease of cellular proliferation DOID:14566 174 0.019
disease of mental health DOID:150 70 0.019
connective tissue disease DOID:65 109 0.018
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.017
bone disease DOID:0080001 88 0.016
immune system disease DOID:2914 155 0.015
sensory system disease DOID:0050155 203 0.015
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.013
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
retinal disease DOID:5679 118 0.011
cardiovascular system disease DOID:1287 106 0.011
brain disease DOID:936 73 0.011
carbohydrate metabolic disorder DOID:2978 55 0.010
cognitive disorder DOID:1561 29 0.010