Homo sapiens

70 known processes

USP13

ubiquitin specific peptidase 13 (isopeptidase T-3)

(Aliases: ISOT3,IsoT-3)

USP13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuromuscular junction development GO:0007528 3 0.179
actin filament based process GO:0030029 224 0.096
protein localization to organelle GO:0033365 280 0.088
amine metabolic process GO:0009308 44 0.079
single organism membrane organization GO:0044802 268 0.078
single organism cellular localization GO:1902580 332 0.075
cell development GO:0048468 328 0.072
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.068
response to hypoxia GO:0001666 96 0.067
determination of adult lifespan GO:0008340 2 0.065
multicellular organismal aging GO:0010259 3 0.064
ribonucleoside monophosphate metabolic process GO:0009161 187 0.063
post embryonic development GO:0009791 2 0.059
organelle localization GO:0051640 84 0.057
cellular amino acid metabolic process GO:0006520 116 0.056
ribonucleoside triphosphate metabolic process GO:0009199 412 0.055
segmentation GO:0035282 4 0.054
response to abiotic stimulus GO:0009628 336 0.054
ribonucleoside triphosphate catabolic process GO:0009203 391 0.053
nervous system development GO:0007399 293 0.053
Fly
locomotory behavior GO:0007626 1 0.051
cellular ketone metabolic process GO:0042180 80 0.050
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.049
intracellular protein transport GO:0006886 270 0.049
cellular amine metabolic process GO:0044106 41 0.048
regulation of cellular amino acid metabolic process GO:0006521 6 0.047
cellular macromolecular complex assembly GO:0034622 324 0.046
regulation of protein localization GO:0032880 296 0.046
chromosome segregation GO:0007059 114 0.046
purine ribonucleotide catabolic process GO:0009154 404 0.046
oogenesis GO:0048477 2 0.045
organophosphate catabolic process GO:0046434 430 0.044
microtubule based process GO:0007017 210 0.044
autophagy GO:0006914 88 0.043
membrane organization GO:0061024 292 0.041
female gamete generation GO:0007292 2 0.040
anterior posterior axis specification GO:0009948 2 0.040
organelle assembly GO:0070925 176 0.039
circulatory system development GO:0072359 262 0.039
regulation of cytoskeleton organization GO:0051493 177 0.038
regulation of cellular component biogenesis GO:0044087 281 0.038
positive regulation of cellular component organization GO:0051130 376 0.038
glycosyl compound catabolic process GO:1901658 413 0.038
actin filament based movement GO:0030048 17 0.038
ubiquitin dependent protein catabolic process GO:0006511 206 0.037
Human Yeast Fly
negative regulation of developmental process GO:0051093 247 0.037
anatomical structure formation involved in morphogenesis GO:0048646 284 0.037
blastoderm segmentation GO:0007350 2 0.036
growth GO:0040007 202 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
Yeast
meiotic chromosome segregation GO:0045132 4 0.036
purine nucleoside triphosphate metabolic process GO:0009144 412 0.035
cellular protein catabolic process GO:0044257 261 0.035
Human Yeast Fly
regulation of protein complex assembly GO:0043254 147 0.035
regulation of cell cycle GO:0051726 393 0.034
mitotic cell cycle GO:0000278 326 0.034
protein catabolic process GO:0030163 325 0.033
Human Yeast Fly
protein localization to nucleus GO:0034504 136 0.033
cardiovascular system development GO:0072358 262 0.032
response to oxygen levels GO:0070482 100 0.032
intracellular mrna localization GO:0008298 1 0.032
cellular component morphogenesis GO:0032989 314 0.032
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.032
negative regulation of protein metabolic process GO:0051248 391 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
neurotransmitter secretion GO:0007269 4 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.030
Human Yeast Fly
regulation of establishment of protein localization GO:0070201 242 0.030
nuclear division GO:0000280 128 0.030
modification dependent macromolecule catabolic process GO:0043632 212 0.030
Human Yeast Fly
regulation of cellular amine metabolic process GO:0033238 11 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
cell morphogenesis GO:0000902 296 0.029
Fly
cellular macromolecule catabolic process GO:0044265 380 0.029
Human Yeast Fly
positive regulation of protein complex assembly GO:0031334 86 0.029
actin filament organization GO:0007015 128 0.029
negative regulation of cell differentiation GO:0045596 171 0.028
proteasomal protein catabolic process GO:0010498 176 0.028
Human Yeast Fly
positive regulation of transport GO:0051050 336 0.028
regulation of cell differentiation GO:0045595 393 0.028
cell projection organization GO:0030030 252 0.027
Fly
establishment of organelle localization GO:0051656 59 0.027
nucleoside monophosphate catabolic process GO:0009125 159 0.027
carbohydrate derivative biosynthetic process GO:1901137 207 0.027
regeneration GO:0031099 4 0.027
actin cytoskeleton organization GO:0030036 207 0.027
regulation of actin filament based process GO:0032970 141 0.027
cellular protein complex assembly GO:0043623 188 0.027
mitotic cell cycle process GO:1903047 286 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.026
morphogenesis of embryonic epithelium GO:0016331 4 0.026
tripartite regional subdivision GO:0007351 2 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
cellular component assembly involved in morphogenesis GO:0010927 73 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
protein localization to membrane GO:0072657 160 0.025
cytoplasmic transport GO:0016482 379 0.025
positive regulation of catabolic process GO:0009896 310 0.025
Human
anterior posterior axis specification embryo GO:0008595 2 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
nucleocytoplasmic transport GO:0006913 176 0.024
regulation of actin cytoskeleton organization GO:0032956 116 0.024
nucleotide catabolic process GO:0009166 408 0.024
cilium assembly GO:0042384 63 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
apoptotic signaling pathway GO:0097190 268 0.024
nucleoside catabolic process GO:0009164 408 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
neuron projection development GO:0031175 106 0.023
Fly
maintenance of location GO:0051235 112 0.023
adult locomotory behavior GO:0008344 1 0.023
regulation of cell cycle process GO:0010564 266 0.023
oocyte differentiation GO:0009994 2 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
immune response GO:0006955 307 0.023
negative regulation of organelle organization GO:0010639 126 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
oocyte development GO:0048599 1 0.022
system process GO:0003008 349 0.022
protein import into nucleus GO:0006606 104 0.022
dna repair GO:0006281 198 0.022
oxidation reduction process GO:0055114 396 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
Human
ribonucleotide catabolic process GO:0009261 405 0.022
carbohydrate metabolic process GO:0005975 207 0.021
Yeast
meiosis i GO:0007127 4 0.021
cell projection morphogenesis GO:0048858 129 0.021
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.021
nuclear migration GO:0007097 1 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.020
regulation of cellular response to stress GO:0080135 244 0.020
vesicle mediated transport GO:0016192 371 0.020
neurogenesis GO:0022008 169 0.020
Fly
regulation of growth GO:0040008 165 0.020
primary neural tube formation GO:0014020 3 0.020
neural tube formation GO:0001841 3 0.020
cilium organization GO:0044782 68 0.020
response to oxygen containing compound GO:1901700 369 0.020
heart formation GO:0060914 2 0.020
lipid metabolic process GO:0006629 381 0.020
regulation of protein polymerization GO:0032271 63 0.020
specification of organ identity GO:0010092 3 0.020
mapk cascade GO:0000165 288 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
methylation GO:0032259 106 0.019
protein complex disassembly GO:0043241 52 0.019
Fly
regulation of response to external stimulus GO:0032101 222 0.019
regulation of protein catabolic process GO:0042176 155 0.019
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.019
potassium ion transport GO:0006813 62 0.019
protein ubiquitination GO:0016567 314 0.019
regulation of cellular component movement GO:0051270 334 0.019
endomembrane system organization GO:0010256 196 0.019
cilium morphogenesis GO:0060271 75 0.019
regulation of protein kinase activity GO:0045859 289 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
response to nitrogen compound GO:1901698 184 0.019
establishment of nucleus localization GO:0040023 1 0.018
epithelium development GO:0060429 227 0.018
cell part morphogenesis GO:0032990 137 0.018
Fly
atp metabolic process GO:0046034 176 0.018
protein targeting GO:0006605 187 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
cellular response to nutrient levels GO:0031669 69 0.018
cellular component disassembly GO:0022411 92 0.018
Fly
negative regulation of cytoskeleton organization GO:0051494 45 0.018
neural tube closure GO:0001843 3 0.018
mitochondrion organization GO:0007005 156 0.018
endodermal cell fate specification GO:0001714 4 0.018
regulation of kinase activity GO:0043549 314 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
single organism nuclear import GO:1902593 104 0.018
histone modification GO:0016570 251 0.018
cell activation GO:0001775 213 0.018
regulation of cell motility GO:2000145 299 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
negative regulation of transport GO:0051051 176 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
Yeast
tissue regeneration GO:0042246 3 0.017
endodermal cell fate commitment GO:0001711 4 0.017
covalent chromatin modification GO:0016569 254 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
positive regulation of organelle organization GO:0010638 195 0.017
rna interference GO:0016246 4 0.017
tube closure GO:0060606 3 0.017
compound eye development GO:0048749 1 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
cellular lipid metabolic process GO:0044255 303 0.017
protein polymerization GO:0051258 71 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
nuclear transport GO:0051169 179 0.016
pattern specification process GO:0007389 43 0.016
protein import GO:0017038 130 0.016
defense response GO:0006952 315 0.016
postsynaptic membrane organization GO:0001941 2 0.016
protein maturation GO:0051604 233 0.016
neuron development GO:0048666 113 0.016
Fly
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 3 0.016
nucleus localization GO:0051647 1 0.016
motor neuron axon guidance GO:0008045 2 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
protein oligomerization GO:0051259 173 0.016
organ formation GO:0048645 3 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
epidermis morphogenesis GO:0048730 3 0.016
endocytosis GO:0006897 159 0.016
cell projection assembly GO:0030031 126 0.016
nuclear import GO:0051170 106 0.016
regulation of proteolysis GO:0030162 293 0.016
Human
secretion GO:0046903 254 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
regulation of canonical wnt signaling pathway GO:0060828 88 0.015
rho protein signal transduction GO:0007266 26 0.015
cofactor metabolic process GO:0051186 87 0.015
protein targeting to nucleus GO:0044744 104 0.015
regulation of intracellular transport GO:0032386 195 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
Human Yeast Fly
regulation of secretion GO:0051046 194 0.015
inner ear morphogenesis GO:0042472 4 0.015
regulation of neurotransmitter secretion GO:0046928 3 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
ras protein signal transduction GO:0007265 73 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
chromatin organization GO:0006325 351 0.015
regulation of protein transport GO:0051223 213 0.015
regulation of protein localization to nucleus GO:1900180 85 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
mitotic nuclear division GO:0007067 119 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
purine containing compound catabolic process GO:0072523 411 0.015
heart development GO:0007507 95 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
regulation of cell development GO:0060284 161 0.014
startle response GO:0001964 3 0.014
organelle fission GO:0048285 149 0.014
regulation of short term neuronal synaptic plasticity GO:0048172 1 0.014
hindbrain development GO:0030902 3 0.014
nitrogen compound transport GO:0071705 191 0.014
peptidyl lysine modification GO:0018205 144 0.014
positive regulation of protein polymerization GO:0032273 45 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
negative regulation of cell cycle GO:0045786 193 0.014
phospholipid metabolic process GO:0006644 99 0.014
atp catabolic process GO:0006200 157 0.014
leukocyte activation GO:0045321 164 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
Human Yeast Fly
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.014
actomyosin structure organization GO:0031032 59 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
wnt signaling pathway GO:0016055 156 0.014
regulation of protein processing GO:0070613 150 0.014
establishment of planar polarity GO:0001736 3 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
regulation of cell migration GO:0030334 289 0.014
lipid biosynthetic process GO:0008610 177 0.014
alpha amino acid metabolic process GO:1901605 72 0.014
cell cell signaling GO:0007267 155 0.014
convergent extension GO:0060026 1 0.014
trabecula morphogenesis GO:0061383 2 0.013
response to organonitrogen compound GO:0010243 156 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
regionalization GO:0003002 29 0.013
positive regulation of dna metabolic process GO:0051054 73 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
salivary gland morphogenesis GO:0007435 4 0.013
innate immune response GO:0045087 178 0.013
macromolecular complex disassembly GO:0032984 60 0.013
Fly
regulation of dna metabolic process GO:0051052 153 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
actin mediated cell contraction GO:0070252 12 0.013
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.013
dna replication GO:0006260 116 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
protein homooligomerization GO:0051260 100 0.013
generation of neurons GO:0048699 152 0.013
Fly
neuron remodeling GO:0016322 2 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
histone methylation GO:0016571 60 0.013
lymphocyte activation GO:0046649 133 0.013
response to fungus GO:0009620 4 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
neuroblast proliferation GO:0007405 4 0.013
cellular response to external stimulus GO:0071496 111 0.013
macromolecule methylation GO:0043414 97 0.013
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
peripheral nervous system development GO:0007422 2 0.013
transmembrane transport GO:0055085 399 0.013
regulation of locomotion GO:0040012 329 0.012
memory GO:0007613 3 0.012
regulation of cell projection organization GO:0031344 107 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
Human
regulation of synaptic plasticity GO:0048167 3 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of protein transport GO:0051222 135 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
heart field specification GO:0003128 2 0.012
double strand break repair GO:0006302 101 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
protein deubiquitination GO:0016579 79 0.012
chromatin modification GO:0016568 298 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
protein localization to plasma membrane GO:0072659 93 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
protein methylation GO:0006479 74 0.012
vesicle organization GO:0016050 62 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
secretion by cell GO:0032940 226 0.012
retinal ganglion cell axon guidance GO:0031290 2 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.012
establishment of tissue polarity GO:0007164 3 0.012
protein processing GO:0016485 226 0.012
cell adhesion GO:0007155 325 0.012
response to external biotic stimulus GO:0043207 261 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
neuron differentiation GO:0030182 138 0.012
Fly
cell growth GO:0016049 160 0.011
tissue morphogenesis GO:0048729 96 0.011
plasma membrane organization GO:0007009 115 0.011
protein modification by small protein removal GO:0070646 92 0.011
associative learning GO:0008306 1 0.011
glial cell migration GO:0008347 4 0.011
spermatid differentiation GO:0048515 4 0.011
regulation of chromosome organization GO:0033044 103 0.011
protein acylation GO:0043543 138 0.011
negative regulation of catabolic process GO:0009895 104 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
positive regulation of transferase activity GO:0051347 227 0.011
endosomal transport GO:0016197 129 0.011
lipid localization GO:0010876 106 0.011
regulation of binding GO:0051098 111 0.011
spindle elongation GO:0051231 4 0.011
negative regulation of cell fate commitment GO:0010454 3 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
head development GO:0060322 108 0.011
regulation of immune response GO:0050776 201 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
actin filament bundle organization GO:0061572 54 0.011
limbic system development GO:0021761 3 0.011
nerve development GO:0021675 4 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
positive regulation of immune system process GO:0002684 283 0.011
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
regulation of cytokine production GO:0001817 232 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of chromosome segregation GO:0051983 44 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
coenzyme metabolic process GO:0006732 65 0.011
regulation of microtubule based process GO:0032886 74 0.011
positive regulation of developmental process GO:0051094 314 0.011
response to other organism GO:0051707 261 0.011
regulation of heart induction GO:0090381 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.010
Human
ion homeostasis GO:0050801 230 0.010
response to hormone GO:0009725 175 0.010
cellular homeostasis GO:0019725 196 0.010
positive regulation of cell projection organization GO:0031346 64 0.010
regulation of multi organism process GO:0043900 157 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
negative regulation of cell death GO:0060548 345 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
negative regulation of protein processing GO:0010955 142 0.010
cellular response to starvation GO:0009267 58 0.010
protein alkylation GO:0008213 74 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
regulation of mapk cascade GO:0043408 262 0.010
signal release GO:0023061 70 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
negative regulation of actin nucleation GO:0051126 3 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
immune effector process GO:0002252 159 0.010
regulation of protein import into nucleus GO:0042306 78 0.010
regulation of homeostatic process GO:0032844 121 0.010
Fly
skeletal muscle tissue growth GO:0048630 2 0.010
glycoprotein metabolic process GO:0009100 110 0.010
negative regulation of proteolysis GO:0045861 132 0.010
organ induction GO:0001759 4 0.010
regulation of cardioblast differentiation GO:0051890 4 0.010
negative regulation of protein modification process GO:0031400 200 0.010

USP13 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.033
nervous system disease DOID:863 431 0.033
musculoskeletal system disease DOID:17 223 0.029
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.024
neurodegenerative disease DOID:1289 102 0.021
disease of metabolism DOID:0014667 295 0.021
sensory system disease DOID:0050155 203 0.020
myopathy DOID:423 104 0.019
muscular disease DOID:0080000 114 0.019
muscle tissue disease DOID:66 113 0.019
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
inherited metabolic disorder DOID:655 242 0.013
muscular dystrophy DOID:9884 51 0.013
retinal disease DOID:5679 118 0.012
disease of mental health DOID:150 70 0.012
retinal degeneration DOID:8466 89 0.011