Homo sapiens

45 known processes

BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

(Aliases: HUCEP-13,KIAA0272,FLJ35406,FLJ37180,DKFZp686N04275,UCHL2)

BAP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 298 0.847
histone deubiquitination GO:0016578 16 0.836
chromatin organization GO:0006325 351 0.707
covalent chromatin modification GO:0016569 254 0.603
histone modification GO:0016570 251 0.496
protein deubiquitination GO:0016579 79 0.431
protein ubiquitination GO:0016567 314 0.337
protein modification by small protein conjugation GO:0032446 342 0.290
protein modification by small protein removal GO:0070646 92 0.289
small gtpase mediated signal transduction GO:0007264 78 0.277
protein polyubiquitination GO:0000209 110 0.203
protein targeting GO:0006605 187 0.193
nucleocytoplasmic transport GO:0006913 176 0.187
single organism cellular localization GO:1902580 332 0.180
positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 4 0.162
dephosphorylation GO:0016311 209 0.149
midgut development GO:0007494 1 0.145
intracellular protein transport GO:0006886 270 0.137
positive regulation of fat cell differentiation GO:0045600 12 0.126
cytoplasmic transport GO:0016482 379 0.126
ras protein signal transduction GO:0007265 73 0.120
amine metabolic process GO:0009308 44 0.116
vesicle mediated transport GO:0016192 371 0.105
cellular ketone metabolic process GO:0042180 80 0.100
cellular amino acid metabolic process GO:0006520 116 0.100
regulation of cell cycle GO:0051726 393 0.100
establishment of protein localization to organelle GO:0072594 172 0.094
regulation of peroxisome proliferator activated receptor signaling pathway GO:0035358 4 0.087
oocyte differentiation GO:0009994 2 0.086
regulation of cell differentiation GO:0045595 393 0.085
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.084
chemical homeostasis GO:0048878 306 0.081
negative regulation of transport GO:0051051 176 0.080
viral latency GO:0019042 1 0.078
alcohol metabolic process GO:0006066 114 0.076
cellular homeostasis GO:0019725 196 0.076
retrograde transport endosome to golgi GO:0042147 45 0.076
bmp signaling pathway GO:0030509 49 0.075
segmentation GO:0035282 4 0.073
response to oxygen containing compound GO:1901700 369 0.071
ribonucleotide catabolic process GO:0009261 405 0.070
protein monoubiquitination GO:0006513 39 0.069
purine nucleoside triphosphate catabolic process GO:0009146 392 0.067
regulation of protein stability GO:0031647 87 0.066
purine ribonucleoside catabolic process GO:0046130 398 0.064
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.064
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.063
positive regulation of cell differentiation GO:0045597 211 0.063
endosomal transport GO:0016197 129 0.063
single organism nuclear import GO:1902593 104 0.061
cellular lipid metabolic process GO:0044255 303 0.060
cell cell signaling GO:0007267 155 0.059
nuclear transport GO:0051169 179 0.058
methylation GO:0032259 106 0.057
interspecies interaction between organisms GO:0044419 156 0.057
enzyme linked receptor protein signaling pathway GO:0007167 303 0.056
small molecule biosynthetic process GO:0044283 157 0.055
release from viral latency GO:0019046 1 0.055
innate immune response GO:0045087 178 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.052
regulation of dna metabolic process GO:0051052 153 0.050
regulation of cellular ketone metabolic process GO:0010565 50 0.050
protein localization to organelle GO:0033365 280 0.050
cellular amine metabolic process GO:0044106 41 0.050
histone h4 k16 acetylation GO:0043984 14 0.049
determination of adult lifespan GO:0008340 2 0.049
retinoic acid receptor signaling pathway GO:0048384 13 0.048
viral process GO:0016032 146 0.048
signal transduction by phosphorylation GO:0023014 297 0.048
nucleoside triphosphate catabolic process GO:0009143 394 0.047
peptidyl lysine modification GO:0018205 144 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.046
Human
regulation of protein localization GO:0032880 296 0.045
protein stabilization GO:0050821 64 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
macromolecule methylation GO:0043414 97 0.044
system process GO:0003008 349 0.043
regulation of intracellular transport GO:0032386 195 0.043
positive regulation of proteolysis GO:0045862 142 0.042
mapk cascade GO:0000165 288 0.042
purine containing compound catabolic process GO:0072523 411 0.042
oocyte development GO:0048599 1 0.041
response to hormone GO:0009725 175 0.041
regulation of establishment of protein localization GO:0070201 242 0.040
guanosine containing compound metabolic process GO:1901068 244 0.040
regulation of transferase activity GO:0051338 355 0.039
negative regulation of cell death GO:0060548 345 0.038
monoubiquitinated protein deubiquitination GO:0035520 6 0.038
negative regulation of cell differentiation GO:0045596 171 0.037
positive regulation of catabolic process GO:0009896 310 0.037
circadian behavior GO:0048512 2 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.037
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
internal protein amino acid acetylation GO:0006475 101 0.035
ribonucleoside catabolic process GO:0042454 406 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
organic hydroxy compound metabolic process GO:1901615 147 0.035
maintenance of location GO:0051235 112 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
lipid metabolic process GO:0006629 381 0.034
multi organism cellular process GO:0044764 156 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.033
protein targeting to nucleus GO:0044744 104 0.033
response to abiotic stimulus GO:0009628 336 0.032
negative regulation of cell cycle GO:0045786 193 0.032
axon regeneration GO:0031103 1 0.032
posttranscriptional regulation of gene expression GO:0010608 213 0.032
guanosine containing compound catabolic process GO:1901069 239 0.031
positive regulation of phosphorylation GO:0042327 394 0.031
peptidyl lysine acetylation GO:0018394 101 0.030
negative regulation of protein modification process GO:0031400 200 0.030
bmp signaling pathway involved in heart development GO:0061312 3 0.030
response to inorganic substance GO:0010035 127 0.030
monocarboxylic acid metabolic process GO:0032787 185 0.029
negative regulation of phosphorylation GO:0042326 174 0.029
rab protein signal transduction GO:0032482 4 0.029
regulation of nucleocytoplasmic transport GO:0046822 98 0.029
regulation of cell motility GO:2000145 299 0.029
defense response GO:0006952 315 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
regulation of cellular response to stress GO:0080135 244 0.028
cytokinesis GO:0000910 96 0.028
regulation of defense response GO:0031347 154 0.028
positive regulation of transport GO:0051050 336 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
modification dependent protein catabolic process GO:0019941 209 0.027
positive regulation of rab gtpase activity GO:0032851 39 0.027
protein localization to nucleus GO:0034504 136 0.026
regulation of fat cell differentiation GO:0045598 23 0.026
digestive system development GO:0055123 75 0.026
oogenesis GO:0048477 2 0.026
positive regulation of gtpase activity GO:0043547 166 0.026
peptidyl threonine dephosphorylation GO:0035970 7 0.026
regulation of cytoplasmic transport GO:1903649 149 0.025
intracellular receptor signaling pathway GO:0030522 104 0.025
lipid biosynthetic process GO:0008610 177 0.025
post embryonic development GO:0009791 2 0.025
regulation of ras gtpase activity GO:0032318 128 0.025
regulation of bmp signaling pathway GO:0030510 27 0.025
metencephalon development GO:0022037 2 0.025
tube development GO:0035295 125 0.025
female gamete generation GO:0007292 2 0.025
anterior posterior axis specification GO:0009948 2 0.025
regulation of multi organism process GO:0043900 157 0.024
histone acetylation GO:0016573 93 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.024
mitotic cell cycle process GO:1903047 286 0.024
regulation of cellular component movement GO:0051270 334 0.024
cell cycle checkpoint GO:0000075 117 0.024
rhythmic behavior GO:0007622 2 0.023
growth hormone secretion GO:0030252 4 0.023
gtp metabolic process GO:0046039 239 0.023
protein k63 linked ubiquitination GO:0070534 31 0.023
regulation of locomotion GO:0040012 329 0.023
cell projection organization GO:0030030 252 0.023
cell cycle arrest GO:0007050 71 0.023
organophosphate catabolic process GO:0046434 430 0.023
regulation of protein kinase activity GO:0045859 289 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
response to biotic stimulus GO:0009607 276 0.022
cellular chemical homeostasis GO:0055082 180 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
fat cell differentiation GO:0045444 32 0.021
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.021
response to organonitrogen compound GO:0010243 156 0.021
cardiovascular system development GO:0072358 262 0.021
cellular protein catabolic process GO:0044257 261 0.021
Human
internal peptidyl lysine acetylation GO:0018393 97 0.021
multicellular organismal aging GO:0010259 3 0.021
demethylation GO:0070988 37 0.020
response to metal ion GO:0010038 84 0.020
monocarboxylic acid biosynthetic process GO:0072330 67 0.020
regulation of kinase activity GO:0043549 314 0.020
protein acylation GO:0043543 138 0.020
regeneration GO:0031099 4 0.020
positive regulation of gtp catabolic process GO:0033126 166 0.020
mitotic cell cycle GO:0000278 326 0.020
dna repair GO:0006281 198 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
bone development GO:0060348 26 0.020
regulation of secretion by cell GO:1903530 177 0.020
glycerolipid metabolic process GO:0046486 107 0.019
nuclear import GO:0051170 106 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
positive regulation of developmental process GO:0051094 314 0.019
protein dephosphorylation GO:0006470 81 0.019
regulation of gtpase activity GO:0043087 180 0.019
response to fungus GO:0009620 4 0.018
immune response GO:0006955 307 0.018
response to lipid GO:0033993 206 0.018
positive regulation of endopeptidase activity GO:0010950 84 0.018
blastoderm segmentation GO:0007350 2 0.018
single organism membrane organization GO:0044802 268 0.018
regulation of protein catabolic process GO:0042176 155 0.018
Human
regulation of protein transport GO:0051223 213 0.018
monoubiquitinated histone h2a deubiquitination GO:0035522 3 0.018
negative regulation of retinoic acid receptor signaling pathway GO:0048387 4 0.018
ectoderm development GO:0007398 3 0.018
histone h4 acetylation GO:0043967 47 0.018
proteasomal protein catabolic process GO:0010498 176 0.018
Human
membrane organization GO:0061024 292 0.018
dna replication GO:0006260 116 0.018
ossification GO:0001503 121 0.018
response to retinoic acid GO:0032526 33 0.018
regulation of cell cycle phase transition GO:1901987 126 0.017
viral life cycle GO:0019058 132 0.017
digestive tract development GO:0048565 75 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
neuromuscular junction development GO:0007528 3 0.017
hindbrain development GO:0030902 3 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
steroid metabolic process GO:0008202 94 0.017
lipid localization GO:0010876 106 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
Human
response to decreased oxygen levels GO:0036293 96 0.016
protein dna complex subunit organization GO:0071824 80 0.016
regulation of immune response GO:0050776 201 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
organic acid biosynthetic process GO:0016053 97 0.016
protein processing GO:0016485 226 0.016
Human
response to oxidative stress GO:0006979 121 0.016
positive regulation of transferase activity GO:0051347 227 0.016
histone h4 k8 acetylation GO:0043982 15 0.016
nervous system development GO:0007399 293 0.016
cellular response to organic cyclic compound GO:0071407 127 0.015
gtp catabolic process GO:0006184 237 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
regulation of cellular protein catabolic process GO:1903362 96 0.015
Human
ion homeostasis GO:0050801 230 0.015
blood vessel development GO:0001568 172 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
locomotory behavior GO:0007626 1 0.015
regulation of proteasomal protein catabolic process GO:0061136 87 0.015
Human
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.015
vesicle organization GO:0016050 62 0.015
regulation of ion transmembrane transport GO:0034765 132 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
activation of immune response GO:0002253 114 0.015
protein catabolic process GO:0030163 325 0.015
Human
autophagy GO:0006914 88 0.015
dna replication independent nucleosome assembly GO:0006336 27 0.014
regulation of proteolysis GO:0030162 293 0.014
Human
actin filament based process GO:0030029 224 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
endocytosis GO:0006897 159 0.014
regulation of viral process GO:0050792 103 0.014
cell growth GO:0016049 160 0.014
apoptotic signaling pathway GO:0097190 268 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
positive regulation of protein localization to nucleus GO:1900182 48 0.014
chromatin assembly or disassembly GO:0006333 78 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
nucleoside catabolic process GO:0009164 408 0.014
neurological system process GO:0050877 163 0.014
positive regulation of cell motility GO:2000147 177 0.014
cell fate determination GO:0001709 3 0.013
dna packaging GO:0006323 77 0.013
protein import into nucleus GO:0006606 104 0.013
regulation of cell migration GO:0030334 289 0.013
g2 m transition of mitotic cell cycle GO:0000086 41 0.013
organelle localization GO:0051640 84 0.013
negative regulation of intracellular transport GO:0032387 60 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
Human
nucleoside phosphate catabolic process GO:1901292 412 0.013
positive regulation of immune system process GO:0002684 283 0.013
memory GO:0007613 3 0.013
mitochondrion organization GO:0007005 156 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
response to acid chemical GO:0001101 66 0.013
regulation of gene expression epigenetic GO:0040029 73 0.013
tripartite regional subdivision GO:0007351 2 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
regulation of growth GO:0040008 165 0.013
carbohydrate homeostasis GO:0033500 31 0.013
nucleotide catabolic process GO:0009166 408 0.013
cell cycle phase transition GO:0044770 173 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
response to cytokine GO:0034097 232 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
immune system development GO:0002520 195 0.012
fatty acid biosynthetic process GO:0006633 46 0.012
negative regulation of developmental process GO:0051093 247 0.012
negative regulation of protein transport GO:0051224 75 0.012
positive regulation of chromosome organization GO:2001252 41 0.012
negative regulation of multi organism process GO:0043901 92 0.012
regulation of homeostatic process GO:0032844 121 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of lipase activity GO:0060191 37 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
regulation of innate immune response GO:0045088 97 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
cellular protein complex assembly GO:0043623 188 0.012
secretion GO:0046903 254 0.012
negative regulation of dna metabolic process GO:0051053 57 0.012
regulation of rab protein signal transduction GO:0032483 39 0.012
cell morphogenesis GO:0000902 296 0.012
histone lysine methylation GO:0034968 50 0.012
response to other organism GO:0051707 261 0.012
compound eye development GO:0048749 1 0.012
protein k63 linked deubiquitination GO:0070536 21 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
positive regulation of protein transport GO:0051222 135 0.012
sleep GO:0030431 2 0.012
growth GO:0040007 202 0.012
cellular response to nutrient levels GO:0031669 69 0.011
positive regulation of defense response GO:0031349 87 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
response to external biotic stimulus GO:0043207 261 0.011
negative regulation of gene silencing by mirna GO:0060965 3 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
response to oxygen levels GO:0070482 100 0.011
mrna metabolic process GO:0016071 175 0.011
protein import GO:0017038 130 0.011
protein complex disassembly GO:0043241 52 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
cellular response to external stimulus GO:0071496 111 0.011
histone h4 k5 acetylation GO:0043981 15 0.011
regulation of metal ion transport GO:0010959 120 0.011
dna replication independent nucleosome organization GO:0034724 27 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
positive regulation of vasoconstriction GO:0045907 3 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
regulation of oocyte development GO:0060281 1 0.011
rna processing GO:0006396 255 0.011
metal ion transport GO:0030001 272 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
regulation of response to external stimulus GO:0032101 222 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
cation homeostasis GO:0055080 189 0.010
secretion by cell GO:0032940 226 0.010
reproductive process GO:0022414 106 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
negative regulation of immune system process GO:0002683 136 0.010
cellular response to lipid GO:0071396 127 0.010
trophectodermal cell differentiation GO:0001829 3 0.010
defense response to other organism GO:0098542 129 0.010
dna modification GO:0006304 27 0.010

BAP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.043
disease of cellular proliferation DOID:14566 174 0.043
organ system cancer DOID:0050686 164 0.043
immune system disease DOID:2914 155 0.022
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
nervous system disease DOID:863 431 0.013
eye disease DOID:5614 149 0.013