Homo sapiens

0 known processes

TYK2

tyrosine kinase 2

(Aliases: JTK1)

TYK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.474
Fly
cellular amine metabolic process GO:0044106 41 0.449
anatomical structure formation involved in morphogenesis GO:0048646 284 0.322
Fly
single organism membrane organization GO:0044802 268 0.291
glycosyl compound catabolic process GO:1901658 413 0.276
amine metabolic process GO:0009308 44 0.263
gtp metabolic process GO:0046039 239 0.197
actin cytoskeleton organization GO:0030036 207 0.189
system process GO:0003008 349 0.172
Fly
guanosine containing compound metabolic process GO:1901068 244 0.166
circulatory system development GO:0072359 262 0.164
membrane organization GO:0061024 292 0.159
nucleotide catabolic process GO:0009166 408 0.151
neurological system process GO:0050877 163 0.149
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.144
gtp catabolic process GO:0006184 237 0.135
ribonucleoside triphosphate metabolic process GO:0009199 412 0.133
purine ribonucleotide catabolic process GO:0009154 404 0.130
nucleoside triphosphate catabolic process GO:0009143 394 0.129
response to abiotic stimulus GO:0009628 336 0.127
cellular amino acid metabolic process GO:0006520 116 0.123
cellular ketone metabolic process GO:0042180 80 0.123
blood vessel development GO:0001568 172 0.116
enzyme linked receptor protein signaling pathway GO:0007167 303 0.115
Human
purine ribonucleoside metabolic process GO:0046128 437 0.113
cell type specific apoptotic process GO:0097285 125 0.113
ribonucleoside triphosphate catabolic process GO:0009203 391 0.113
cell development GO:0048468 328 0.109
Fly
rho protein signal transduction GO:0007266 26 0.103
regulation of response to external stimulus GO:0032101 222 0.103
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.102
sensory perception GO:0007600 103 0.102
oxidation reduction process GO:0055114 396 0.097
protein targeting GO:0006605 187 0.096
memory GO:0007613 3 0.095
Fly
ribonucleoside catabolic process GO:0042454 406 0.092
response to salt stress GO:0009651 3 0.089
hematopoietic or lymphoid organ development GO:0048534 186 0.088
Fly
regulation of locomotion GO:0040012 329 0.087
organophosphate catabolic process GO:0046434 430 0.087
hemopoiesis GO:0030097 180 0.086
Fly
plasma membrane organization GO:0007009 115 0.086
positive regulation of cellular catabolic process GO:0031331 284 0.080
actin filament organization GO:0007015 128 0.077
cardiovascular system development GO:0072358 262 0.077
positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 3 0.074
cellular homeostasis GO:0019725 196 0.074
regulation of cellular component biogenesis GO:0044087 281 0.071
negative regulation of cell death GO:0060548 345 0.071
nucleoside triphosphate metabolic process GO:0009141 422 0.070
purine nucleotide catabolic process GO:0006195 405 0.070
cellular response to oxygen containing compound GO:1901701 276 0.069
Human
cellular response to nitrogen compound GO:1901699 144 0.069
Human
nucleoside phosphate catabolic process GO:1901292 412 0.068
positive regulation of immune system process GO:0002684 283 0.068
synaptic vesicle endocytosis GO:0048488 2 0.067
associative learning GO:0008306 1 0.066
sensory perception of smell GO:0007608 2 0.066
purine containing compound catabolic process GO:0072523 411 0.065
vesicle organization GO:0016050 62 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.062
Human
compound eye development GO:0048749 1 0.062
Fly
negative regulation of cellular component organization GO:0051129 235 0.059
cellular response to endogenous stimulus GO:0071495 336 0.059
Human
regulation of mapk cascade GO:0043408 262 0.059
alcohol metabolic process GO:0006066 114 0.058
lipid metabolic process GO:0006629 381 0.057
endomembrane system organization GO:0010256 196 0.057
negative regulation of catalytic activity GO:0043086 335 0.057
biological adhesion GO:0022610 331 0.056
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.056
single organism cellular localization GO:1902580 332 0.056
protein autophosphorylation GO:0046777 123 0.055
regulation of cell differentiation GO:0045595 393 0.054
Fly
nucleoside catabolic process GO:0009164 408 0.053
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
response to biotic stimulus GO:0009607 276 0.051
Fly
urogenital system development GO:0001655 65 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
positive regulation of locomotion GO:0040017 186 0.049
ras protein signal transduction GO:0007265 73 0.049
purine ribonucleoside catabolic process GO:0046130 398 0.049
regulation of purine nucleotide catabolic process GO:0033121 205 0.048
ribonucleotide catabolic process GO:0009261 405 0.048
purine nucleoside triphosphate metabolic process GO:0009144 412 0.048
behavior GO:0007610 112 0.047
Fly
epithelium development GO:0060429 227 0.047
Fly
protein localization to organelle GO:0033365 280 0.046
cell division GO:0051301 168 0.046
segmentation GO:0035282 4 0.045
Fly
fatty acid metabolic process GO:0006631 115 0.045
immune system development GO:0002520 195 0.045
Fly
chromatin organization GO:0006325 351 0.045
Human
chemical homeostasis GO:0048878 306 0.045
cellular response to peptide GO:1901653 59 0.045
Human
actin filament based process GO:0030029 224 0.044
Fly
cellular macromolecular complex assembly GO:0034622 324 0.044
leukocyte migration GO:0050900 107 0.044
ion homeostasis GO:0050801 230 0.044
negative regulation of developmental process GO:0051093 247 0.044
Fly
protein localization to nucleus GO:0034504 136 0.043
positive regulation of cell motility GO:2000147 177 0.043
cellular component morphogenesis GO:0032989 314 0.043
Fly
regulation of multi organism process GO:0043900 157 0.043
monovalent inorganic cation homeostasis GO:0055067 37 0.042
cellular ion homeostasis GO:0006873 168 0.042
negative regulation of intracellular signal transduction GO:1902532 183 0.042
innate immune response GO:0045087 178 0.042
cellular lipid metabolic process GO:0044255 303 0.042
histone modification GO:0016570 251 0.041
Human
cellular cation homeostasis GO:0030003 163 0.041
peptidyl serine phosphorylation GO:0018105 101 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.040
dephosphorylation GO:0016311 209 0.040
negative regulation of cellular protein metabolic process GO:0032269 353 0.040
cation homeostasis GO:0055080 189 0.040
positive regulation of catabolic process GO:0009896 310 0.040
peptidyl serine modification GO:0018209 106 0.040
multicellular organismal aging GO:0010259 3 0.039
signal transduction by phosphorylation GO:0023014 297 0.039
morphogenesis of a polarized epithelium GO:0001738 3 0.038
Fly
response to organonitrogen compound GO:0010243 156 0.038
Human
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
cell morphogenesis GO:0000902 296 0.038
Fly
response to virus GO:0009615 126 0.037
Fly
regulation of small gtpase mediated signal transduction GO:0051056 156 0.037
synaptic vesicle recycling GO:0036465 3 0.036
regulation of growth GO:0040008 165 0.036
positive regulation of protein phosphorylation GO:0001934 313 0.036
purine nucleoside catabolic process GO:0006152 398 0.035
cell junction maintenance GO:0034331 4 0.035
cell projection organization GO:0030030 252 0.035
negative regulation of apoptotic process GO:0043066 316 0.034
regulation of protein kinase activity GO:0045859 289 0.034
protein targeting to nucleus GO:0044744 104 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
positive regulation of gtp catabolic process GO:0033126 166 0.033
guanosine containing compound catabolic process GO:1901069 239 0.033
post embryonic organ development GO:0048569 1 0.033
Fly
regulation of synaptic plasticity GO:0048167 3 0.033
negative regulation of phosphorylation GO:0042326 174 0.033
positive regulation of rho gtpase activity GO:0032321 56 0.033
positive regulation of cell differentiation GO:0045597 211 0.033
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.032
negative regulation of protein phosphorylation GO:0001933 140 0.032
regulation of ras protein signal transduction GO:0046578 155 0.032
somatic muscle development GO:0007525 1 0.032
sensory perception of mechanical stimulus GO:0050954 37 0.032
regulation of cytoskeleton organization GO:0051493 177 0.032
spermatid development GO:0007286 4 0.031
response to lipid GO:0033993 206 0.031
glycerolipid metabolic process GO:0046486 107 0.031
regulation of gtp catabolic process GO:0033124 180 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
regulation of peptidyl serine phosphorylation GO:0033135 50 0.031
vasculature development GO:0001944 181 0.031
negative regulation of protein modification process GO:0031400 200 0.031
lytic vacuole organization GO:0080171 24 0.031
positive regulation of cell development GO:0010720 92 0.031
endocytosis GO:0006897 159 0.031
autophagy GO:0006914 88 0.030
negative regulation of hydrolase activity GO:0051346 182 0.030
cellular chemical homeostasis GO:0055082 180 0.030
sex determination GO:0007530 3 0.030
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
chemotaxis GO:0006935 157 0.030
single organism nuclear import GO:1902593 104 0.029
negative regulation of programmed cell death GO:0043069 321 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
establishment of protein localization to organelle GO:0072594 172 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
maintenance of location GO:0051235 112 0.029
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
short term memory GO:0007614 1 0.028
positive regulation of map kinase activity GO:0043406 80 0.028
regulation of innate immune response GO:0045088 97 0.028
vesicle mediated transport GO:0016192 371 0.028
blastoderm segmentation GO:0007350 2 0.028
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
regulation of nucleotide catabolic process GO:0030811 205 0.028
monovalent inorganic cation transport GO:0015672 128 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.027
necrotic cell death GO:0070265 21 0.027
regulation of protein complex assembly GO:0043254 147 0.027
establishment of organelle localization GO:0051656 59 0.027
long term memory GO:0007616 2 0.027
Fly
organ morphogenesis GO:0009887 147 0.027
Fly
cellular macromolecule catabolic process GO:0044265 380 0.027
rhythmic behavior GO:0007622 2 0.027
Fly
defense response to other organism GO:0098542 129 0.027
Fly
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
regulation of dna metabolic process GO:0051052 153 0.026
taxis GO:0042330 157 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
Human
regulation of map kinase activity GO:0043405 108 0.025
positive regulation of cytoskeleton organization GO:0051495 83 0.025
covalent chromatin modification GO:0016569 254 0.025
Human
regulation of cell cycle GO:0051726 393 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
positive regulation of cell migration GO:0030335 172 0.024
nuclear import GO:0051170 106 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
regulation of cell motility GO:2000145 299 0.024
regulation of protein serine threonine kinase activity GO:0071900 179 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
Human
response to cytokine GO:0034097 232 0.024
Human
organelle assembly GO:0070925 176 0.024
locomotory behavior GO:0007626 1 0.024
Fly
blood vessel morphogenesis GO:0048514 162 0.023
receptor internalization GO:0031623 43 0.023
regulation of protein transport GO:0051223 213 0.023
positive regulation of rab gtpase activity GO:0032851 39 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
photoreceptor cell differentiation GO:0046530 2 0.023
Fly
defense response GO:0006952 315 0.023
Human Fly
growth GO:0040007 202 0.023
regulation of cellular response to stress GO:0080135 244 0.022
regulation of cellular component movement GO:0051270 334 0.022
regulation of cell cycle process GO:0010564 266 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
protein catabolic process GO:0030163 325 0.022
rna processing GO:0006396 255 0.022
mapk cascade GO:0000165 288 0.022
mitochondrion organization GO:0007005 156 0.022
lipid biosynthetic process GO:0008610 177 0.022
protein import into nucleus GO:0006606 104 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
regulation of cell adhesion GO:0030155 166 0.022
Human
response to oxygen containing compound GO:1901700 369 0.022
Human
positive regulation of mapk cascade GO:0043410 190 0.022
cell projection assembly GO:0030031 126 0.022
positive regulation of cell cycle process GO:0090068 106 0.022
positive regulation of protein transport GO:0051222 135 0.022
cellular biogenic amine metabolic process GO:0006576 34 0.022
negative regulation of protein metabolic process GO:0051248 391 0.021
spermatid differentiation GO:0048515 4 0.021
negative regulation of phosphatase activity GO:0010923 61 0.021
regulation of kinase activity GO:0043549 314 0.021
nuclear transport GO:0051169 179 0.021
regulation of transferase activity GO:0051338 355 0.021
cellular response to biotic stimulus GO:0071216 71 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
regulation of response to biotic stimulus GO:0002831 55 0.021
cell adhesion GO:0007155 325 0.021
Human
regulation of phosphatase activity GO:0010921 81 0.021
regulation of gtpase activity GO:0043087 180 0.020
response to radiation GO:0009314 151 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
steroid metabolic process GO:0008202 94 0.020
organelle localization GO:0051640 84 0.020
epithelial cell differentiation GO:0030855 141 0.020
Fly
stem cell division GO:0017145 2 0.020
phagosome maturation GO:0090382 9 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
monocarboxylic acid metabolic process GO:0032787 185 0.020
cellular protein complex assembly GO:0043623 188 0.020
protein polymerization GO:0051258 71 0.020
regulation of defense response GO:0031347 154 0.020
Human
positive regulation of defense response GO:0031349 87 0.020
negative regulation of dephosphorylation GO:0035305 63 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
phosphatidylethanolamine biosynthetic process GO:0006646 4 0.020
regulation of rho protein signal transduction GO:0035023 79 0.020
regulation of epithelial cell proliferation GO:0050678 113 0.020
monosaccharide metabolic process GO:0005996 74 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
negative regulation of cell proliferation GO:0008285 228 0.019
cell cell junction organization GO:0045216 69 0.019
regulation of secretion by cell GO:1903530 177 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
Fly
nucleoside monophosphate catabolic process GO:0009125 159 0.019
regeneration GO:0031099 4 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.019
atp catabolic process GO:0006200 157 0.019
caveolin mediated endocytosis GO:0072584 4 0.019
regulation of immune response GO:0050776 201 0.018
regulation of dephosphorylation GO:0035303 96 0.018
carbohydrate transport GO:0008643 37 0.018
glycerophospholipid metabolic process GO:0006650 84 0.018
cell junction organization GO:0034330 79 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
regulation of secretion GO:0051046 194 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
determination of adult lifespan GO:0008340 2 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
regulation of autophagy GO:0010506 52 0.018
response to other organism GO:0051707 261 0.018
Fly
cellular response to cytokine stimulus GO:0071345 181 0.018
Human
positive regulation of gtpase activity GO:0043547 166 0.018
vacuole organization GO:0007033 44 0.017
generation of precursor metabolites and energy GO:0006091 68 0.017
positive regulation of immune response GO:0050778 159 0.017
protein ubiquitination GO:0016567 314 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
phagosome lysosome fusion GO:0090385 4 0.017
regulation of defense response to virus GO:0050688 33 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
membrane lipid metabolic process GO:0006643 53 0.017
endothelial cell proliferation GO:0001935 65 0.017
negative regulation of endocytosis GO:0045806 19 0.017
regulation of vasculature development GO:1901342 97 0.017
regulation of cell migration GO:0030334 289 0.017
positive regulation of cell division GO:0051781 59 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
oogenesis GO:0048477 2 0.017
Fly
regulation of cell projection organization GO:0031344 107 0.017
receptor mediated endocytosis GO:0006898 84 0.017
interspecies interaction between organisms GO:0044419 156 0.017
angiogenesis GO:0001525 147 0.017
protein localization to membrane GO:0072657 160 0.017
cell chemotaxis GO:0060326 112 0.016
renal system development GO:0072001 63 0.016
regulation of endocytosis GO:0030100 72 0.016
positive regulation of cytokine production GO:0001819 167 0.016
hydrogen transport GO:0006818 23 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
viral process GO:0016032 146 0.016
positive regulation of innate immune response GO:0045089 79 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
dna repair GO:0006281 198 0.016
positive regulation of transport GO:0051050 336 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
neuroblast proliferation GO:0007405 4 0.016
golgi vesicle transport GO:0048193 80 0.016
positive regulation of transferase activity GO:0051347 227 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
positive regulation of developmental process GO:0051094 314 0.016
sensory perception of chemical stimulus GO:0007606 38 0.016
endosomal transport GO:0016197 129 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
negative regulation of kinase activity GO:0033673 106 0.016
immune effector process GO:0002252 159 0.016
Fly
regulation of antimicrobial humoral response GO:0002759 1 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
positive regulation of necrotic cell death GO:0010940 4 0.015
regulation of protein targeting GO:1903533 91 0.015
cellular response to lipopolysaccharide GO:0071222 57 0.015
cellular response to peptide hormone stimulus GO:0071375 56 0.015
Human
regulation of anatomical structure size GO:0090066 101 0.015
somatic stem cell maintenance GO:0035019 4 0.015
positive regulation of epithelial cell proliferation GO:0050679 65 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
negative regulation of growth GO:0045926 97 0.015
mrna metabolic process GO:0016071 175 0.015
cation transport GO:0006812 331 0.015
regulation of rho gtpase activity GO:0032319 66 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
Human
regulation of nucleoside metabolic process GO:0009118 209 0.015
regulation of protein localization GO:0032880 296 0.015
small molecule biosynthetic process GO:0044283 157 0.015
negative regulation of immune system process GO:0002683 136 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
regulation of cellular ph GO:0030641 17 0.014
female gamete generation GO:0007292 2 0.014
Fly
protein processing GO:0016485 226 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
regulation of leukocyte differentiation GO:1902105 61 0.014
extracellular structure organization GO:0043062 41 0.014
regulation of defense response to virus by host GO:0050691 22 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
apoptotic signaling pathway GO:0097190 268 0.014
cell part morphogenesis GO:0032990 137 0.014
g protein coupled receptor signaling pathway GO:0007186 207 0.014
cilium organization GO:0044782 68 0.014
regulation of short term neuronal synaptic plasticity GO:0048172 1 0.014
cell junction assembly GO:0034329 67 0.014
actin polymerization or depolymerization GO:0008154 56 0.013
regulation of endothelial cell proliferation GO:0001936 56 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
cell projection morphogenesis GO:0048858 129 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
rna splicing GO:0008380 131 0.013
regulation of protein import into nucleus GO:0042306 78 0.013
cell growth GO:0016049 160 0.013
multi organism cellular process GO:0044764 156 0.013
leukocyte apoptotic process GO:0071887 31 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
actin filament bundle organization GO:0061572 54 0.013
response to extracellular stimulus GO:0009991 85 0.013
positive regulation of neural precursor cell proliferation GO:2000179 2 0.013
response to oxidative stress GO:0006979 121 0.013
secretion by cell GO:0032940 226 0.013
protein import GO:0017038 130 0.013
dna conformation change GO:0071103 113 0.013
chromatin modification GO:0016568 298 0.013
Human
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
brain development GO:0007420 97 0.013
nerve development GO:0021675 4 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
embryo development GO:0009790 123 0.013
Fly
atp metabolic process GO:0046034 176 0.013
macromolecule deacylation GO:0098732 41 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.012
stress fiber assembly GO:0043149 40 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
regulation of immune effector process GO:0002697 91 0.012
positive regulation of response to external stimulus GO:0032103 88 0.012
regulation of protein polymerization GO:0032271 63 0.012
protein kinase b signaling GO:0043491 69 0.012
negative regulation of mapk cascade GO:0043409 56 0.012
alpha amino acid metabolic process GO:1901605 72 0.012
positive regulation of lymphocyte activation GO:0051251 73 0.012
defense response to virus GO:0051607 71 0.012
Fly
negative regulation of protein kinase activity GO:0006469 98 0.012
hexose metabolic process GO:0019318 55 0.012
positive regulation of organelle organization GO:0010638 195 0.012
cytoplasmic transport GO:0016482 379 0.012
cellular lipid catabolic process GO:0044242 65 0.012
negative regulation of phagocytosis GO:0050765 4 0.012
ethanolamine containing compound metabolic process GO:0042439 26 0.012
developmental growth GO:0048589 48 0.012
neurotrophin trk receptor signaling pathway GO:0048011 4 0.012
regulation of protein catabolic process GO:0042176 155 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of adaptive immune response GO:0002819 33 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
response to peptide hormone GO:0043434 61 0.012
Human
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
response to peptide GO:1901652 65 0.012
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 26 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
regulation of cellular component size GO:0032535 82 0.012
neuron death GO:0070997 65 0.012
regulation of cell division GO:0051302 116 0.012
regulation of tor signaling GO:0032006 30 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
myeloid leukocyte differentiation GO:0002573 60 0.011
positive regulation of proteolysis GO:0045862 142 0.011
response to hypoxia GO:0001666 96 0.011
negative regulation of membrane tubulation GO:1903526 2 0.011
intracellular protein transport GO:0006886 270 0.011
response to hormone GO:0009725 175 0.011
Human
regulation of actin filament polymerization GO:0030833 50 0.011
regulation of body fluid levels GO:0050878 99 0.011
central nervous system development GO:0007417 123 0.011
cellular protein catabolic process GO:0044257 261 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
neuromuscular junction development GO:0007528 3 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
regulation of leukocyte mediated immunity GO:0002703 38 0.011
mammary gland morphogenesis GO:0060443 2 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
negative regulation of regulated secretory pathway GO:1903306 1 0.011
microtubule based process GO:0007017 210 0.011
response to nitrogen compound GO:1901698 184 0.011
Human
gamma delta t cell activation GO:0046629 3 0.011
macroautophagy GO:0016236 39 0.011
positive regulation of cell death GO:0010942 263 0.011
interleukin 4 mediated signaling pathway GO:0035771 3 0.011
Human
epithelial cell proliferation GO:0050673 128 0.011
positive regulation of cell activation GO:0050867 81 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
receptor metabolic process GO:0043112 81 0.011
regulation of dna repair GO:0006282 47 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
cellular amide metabolic process GO:0043603 69 0.010
somitogenesis GO:0001756 2 0.010

TYK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.139
nervous system disease DOID:863 431 0.110
neuropathy DOID:870 52 0.110
central nervous system disease DOID:331 186 0.088
immune system disease DOID:2914 155 0.051
Human
bone remodeling disease DOID:0080005 26 0.047
bone disease DOID:0080001 88 0.047
osteopetrosis DOID:13533 9 0.047
connective tissue disease DOID:65 109 0.047
osteosclerosis DOID:4254 16 0.047
neuromuscular disease DOID:440 38 0.033
myopathy DOID:423 104 0.026
muscular disease DOID:0080000 114 0.026
muscle tissue disease DOID:66 113 0.026
disease of metabolism DOID:0014667 295 0.026
kidney disease DOID:557 36 0.023
urinary system disease DOID:18 40 0.023
centronuclear myopathy DOID:14717 7 0.022
disease of mental health DOID:150 70 0.015
charcot marie tooth disease DOID:10595 33 0.013
cancer DOID:162 167 0.013
Human
disease of cellular proliferation DOID:14566 174 0.013
Human
organ system cancer DOID:0050686 164 0.013
Human
hypersensitivity reaction disease DOID:0060056 25 0.011
hypersensitivity reaction type ii disease DOID:417 19 0.011