Homo sapiens

7 known processes

PAPPA

pregnancy-associated plasma protein A, pappalysin 1

(Aliases: DIPLA1,PAPPA1,IGFBP-4ase,PAPA,PAPP-A,ASBABP2)

PAPPA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of developmental process GO:0051094 314 0.547
anatomical structure formation involved in morphogenesis GO:0048646 284 0.471
cellular ketone metabolic process GO:0042180 80 0.393
positive regulation of cell differentiation GO:0045597 211 0.356
regulation of locomotion GO:0040012 329 0.354
cellular response to endogenous stimulus GO:0071495 336 0.348
mesenchymal cell differentiation GO:0048762 52 0.348
regulation of cellular ketone metabolic process GO:0010565 50 0.344
neuron fate commitment GO:0048663 2 0.335
mesenchymal cell development GO:0014031 50 0.295
embryonic morphogenesis GO:0048598 85 0.274
circulatory system development GO:0072359 262 0.269
mesenchyme development GO:0060485 59 0.265
regulation of cellular amine metabolic process GO:0033238 11 0.261
nervous system development GO:0007399 293 0.255
negative regulation of multicellular organismal process GO:0051241 317 0.255
cellular amine metabolic process GO:0044106 41 0.254
regulation of hormone levels GO:0010817 125 0.253
positive regulation of cellular amine metabolic process GO:0033240 7 0.243
cardiovascular system development GO:0072358 262 0.240
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.232
regulation of cell differentiation GO:0045595 393 0.227
regulation of cellular component movement GO:0051270 334 0.222
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.215
blood vessel morphogenesis GO:0048514 162 0.213
response to growth factor GO:0070848 205 0.211
lipid metabolic process GO:0006629 381 0.206
positive regulation of cell motility GO:2000147 177 0.198
amine metabolic process GO:0009308 44 0.197
organ morphogenesis GO:0009887 147 0.195
regulation of cell motility GO:2000145 299 0.192
tube morphogenesis GO:0035239 95 0.180
epithelium migration GO:0090132 119 0.179
cellular component morphogenesis GO:0032989 314 0.176
cytokine production GO:0001816 247 0.175
ameboidal type cell migration GO:0001667 135 0.174
cellular response to growth factor stimulus GO:0071363 197 0.173
regulation of cell migration GO:0030334 289 0.162
enzyme linked receptor protein signaling pathway GO:0007167 303 0.161
tissue morphogenesis GO:0048729 96 0.160
stem cell differentiation GO:0048863 93 0.159
positive regulation of mapk cascade GO:0043410 190 0.158
negative regulation of androgen receptor activity GO:2000824 2 0.156
tube development GO:0035295 125 0.155
epithelium development GO:0060429 227 0.155
regulation of cellular amino acid metabolic process GO:0006521 6 0.154
negative regulation of developmental process GO:0051093 247 0.154
epithelial to mesenchymal transition GO:0001837 48 0.153
response to organic cyclic compound GO:0014070 204 0.150
cellular amino acid metabolic process GO:0006520 116 0.148
positive regulation of phosphorylation GO:0042327 394 0.146
regulation of ossification GO:0030278 58 0.143
motor neuron axon guidance GO:0008045 2 0.143
stem cell development GO:0048864 69 0.138
regulation of anatomical structure morphogenesis GO:0022603 286 0.138
skeletal system development GO:0001501 79 0.135
cell development GO:0048468 328 0.132
response to hormone GO:0009725 175 0.131
cell morphogenesis GO:0000902 296 0.130
cell adhesion GO:0007155 325 0.127
positive regulation of cell proliferation GO:0008284 301 0.126
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.124
segmentation GO:0035282 4 0.123
osteoblast differentiation GO:0001649 92 0.121
regulation of cytokine production GO:0001817 232 0.119
regulation of cellular component biogenesis GO:0044087 281 0.117
ossification GO:0001503 121 0.114
negative regulation of cellular component organization GO:0051129 235 0.114
kidney development GO:0001822 53 0.112
positive regulation of cellular component movement GO:0051272 181 0.110
cellular response to oxygen containing compound GO:1901701 276 0.110
atrioventricular valve development GO:0003171 3 0.109
bmp signaling pathway GO:0030509 49 0.107
regulation of cell development GO:0060284 161 0.107
positive regulation of locomotion GO:0040017 186 0.106
neurogenesis GO:0022008 169 0.106
response to biotic stimulus GO:0009607 276 0.105
response to lipid GO:0033993 206 0.102
negative regulation of cell growth GO:0030308 83 0.101
cell morphogenesis involved in differentiation GO:0000904 144 0.101
negative regulation of cell differentiation GO:0045596 171 0.101
neural crest cell development GO:0014032 3 0.101
cytoplasmic transport GO:0016482 379 0.100
tissue migration GO:0090130 119 0.099
endocardial cushion development GO:0003197 3 0.099
positive regulation of protein phosphorylation GO:0001934 313 0.098
response to other organism GO:0051707 261 0.098
digestive system development GO:0055123 75 0.097
response to abiotic stimulus GO:0009628 336 0.096
digestive tract development GO:0048565 75 0.094
lipid biosynthetic process GO:0008610 177 0.094
response to oxygen containing compound GO:1901700 369 0.093
gastrulation GO:0007369 51 0.092
neuron differentiation GO:0030182 138 0.092
pattern specification process GO:0007389 43 0.092
regulation of cell growth GO:0001558 135 0.092
head development GO:0060322 108 0.092
positive regulation of cell migration GO:0030335 172 0.090
cardiac epithelial to mesenchymal transition GO:0060317 3 0.089
regulation of wnt signaling pathway GO:0030111 123 0.088
post embryonic development GO:0009791 2 0.087
secretion GO:0046903 254 0.086
peptidyl tyrosine modification GO:0018212 170 0.084
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.081
response to external biotic stimulus GO:0043207 261 0.081
positive regulation of programmed cell death GO:0043068 249 0.080
positive regulation of transport GO:0051050 336 0.080
single organism cellular localization GO:1902580 332 0.079
cell fate determination GO:0001709 3 0.078
negative regulation of wnt signaling pathway GO:0030178 69 0.077
vasculature development GO:0001944 181 0.077
epithelial cell migration GO:0010631 119 0.076
angiogenesis GO:0001525 147 0.075
atrioventricular valve morphogenesis GO:0003181 2 0.074
regulation of bmp signaling pathway GO:0030510 27 0.074
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.074
regulation of secretion GO:0051046 194 0.073
positive regulation of cell development GO:0010720 92 0.072
urogenital system development GO:0001655 65 0.071
regulation of epithelial cell migration GO:0010632 93 0.070
apoptotic signaling pathway GO:0097190 268 0.070
regulation of osteoblast differentiation GO:0045667 38 0.070
brain development GO:0007420 97 0.068
muscle structure development GO:0061061 98 0.068
positive regulation of apoptotic process GO:0043065 246 0.067
regulation of cell cell adhesion GO:0022407 57 0.067
regulation of binding GO:0051098 111 0.067
growth GO:0040007 202 0.067
small molecule biosynthetic process GO:0044283 157 0.066
regulation of cellular response to stress GO:0080135 244 0.066
neuron projection development GO:0031175 106 0.065
epithelial cell differentiation GO:0030855 141 0.065
positive regulation of cell death GO:0010942 263 0.065
heart development GO:0007507 95 0.064
heart valve formation GO:0003188 2 0.064
hindbrain development GO:0030902 3 0.064
anterior posterior axis specification GO:0009948 2 0.064
cranial nerve development GO:0021545 4 0.063
cell cell signaling GO:0007267 155 0.063
blood vessel development GO:0001568 172 0.062
renal system development GO:0072001 63 0.062
response to transforming growth factor beta GO:0071559 94 0.061
neural crest cell migration GO:0001755 2 0.061
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.060
regulation of secretion by cell GO:1903530 177 0.060
mitotic cell cycle GO:0000278 326 0.060
metal ion transport GO:0030001 272 0.059
female gamete generation GO:0007292 2 0.059
mesonephros development GO:0001823 17 0.059
steroid biosynthetic process GO:0006694 46 0.059
positive regulation of proteolysis GO:0045862 142 0.059
defense response GO:0006952 315 0.059
regulation of canonical wnt signaling pathway GO:0060828 88 0.059
single organism cell adhesion GO:0098602 179 0.058
generation of neurons GO:0048699 152 0.057
negative regulation of cell cycle GO:0045786 193 0.057
multicellular organismal aging GO:0010259 3 0.057
central nervous system development GO:0007417 123 0.056
regulation of cell adhesion GO:0030155 166 0.056
negative regulation of cell proliferation GO:0008285 228 0.056
intracellular receptor signaling pathway GO:0030522 104 0.055
negative regulation of cell migration GO:0030336 102 0.055
secretion by cell GO:0032940 226 0.054
embryonic epithelial tube formation GO:0001838 4 0.054
wnt signaling pathway GO:0016055 156 0.054
somitogenesis GO:0001756 2 0.054
negative regulation of cell death GO:0060548 345 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.053
peptidyl tyrosine phosphorylation GO:0018108 170 0.052
intracellular protein transport GO:0006886 270 0.052
forebrain generation of neurons GO:0021872 3 0.052
negative regulation of growth GO:0045926 97 0.052
negative regulation of locomotion GO:0040013 118 0.052
regulation of stem cell differentiation GO:2000736 56 0.052
regulation of cellular response to growth factor stimulus GO:0090287 76 0.052
negative regulation of protein metabolic process GO:0051248 391 0.052
system process GO:0003008 349 0.051
positive regulation of intracellular transport GO:0032388 104 0.051
kidney epithelium development GO:0072073 25 0.051
positive regulation of hydrolase activity GO:0051345 331 0.050
regulation of vasculature development GO:1901342 97 0.050
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.050
hematopoietic or lymphoid organ development GO:0048534 186 0.049
cell substrate adhesion GO:0031589 132 0.049
morphogenesis of an epithelium GO:0002009 60 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
s shaped body morphogenesis GO:0072050 4 0.048
nitrogen compound transport GO:0071705 191 0.048
cellular response to dna damage stimulus GO:0006974 379 0.048
regulation of protein transport GO:0051223 213 0.048
nerve development GO:0021675 4 0.048
positive regulation of keratinocyte migration GO:0051549 4 0.048
hormone secretion GO:0046879 65 0.048
renal vesicle development GO:0072087 4 0.048
embryo development GO:0009790 123 0.048
immune response GO:0006955 307 0.048
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.047
regulation of proteolysis GO:0030162 293 0.047
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.047
primary neural tube formation GO:0014020 3 0.047
regulation of peptidase activity GO:0052547 180 0.046
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.046
regulation of mapk cascade GO:0043408 262 0.045
chemotaxis GO:0006935 157 0.045
stem cell division GO:0017145 2 0.044
chordate embryonic development GO:0043009 34 0.044
regionalization GO:0003002 29 0.044
activin receptor signaling pathway GO:0032924 24 0.044
digestive tract morphogenesis GO:0048546 56 0.043
canonical wnt signaling pathway GO:0060070 116 0.043
organonitrogen compound biosynthetic process GO:1901566 200 0.043
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.043
biological adhesion GO:0022610 331 0.042
positive regulation of peptidase activity GO:0010952 88 0.042
chemical homeostasis GO:0048878 306 0.042
taxis GO:0042330 157 0.042
metal ion homeostasis GO:0055065 169 0.042
reproductive process GO:0022414 106 0.042
nuclear transport GO:0051169 179 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.041
regulation of angiogenesis GO:0045765 92 0.041
cellular metal ion homeostasis GO:0006875 146 0.041
calcium ion homeostasis GO:0055074 122 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
cellular response to organic cyclic compound GO:0071407 127 0.040
negative regulation of bmp signaling pathway GO:0030514 17 0.040
mapk cascade GO:0000165 288 0.040
muscle cell differentiation GO:0042692 63 0.039
regulation of growth GO:0040008 165 0.039
positive regulation of cytoplasmic transport GO:1903651 82 0.039
regulation of cell cycle GO:0051726 393 0.039
positive regulation of hormone biosynthetic process GO:0046886 4 0.039
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.038
cell proliferation involved in heart valve development GO:2000793 1 0.038
regulation of purine nucleotide metabolic process GO:1900542 264 0.038
regulation of cell morphogenesis GO:0022604 153 0.038
cell growth GO:0016049 160 0.038
embryonic organ development GO:0048568 36 0.038
cation transport GO:0006812 331 0.038
cellular cation homeostasis GO:0030003 163 0.038
connective tissue development GO:0061448 39 0.038
potassium ion transmembrane transport GO:0071805 60 0.038
regulation of establishment of protein localization GO:0070201 242 0.038
muscle organ development GO:0007517 56 0.037
neural tube formation GO:0001841 3 0.037
morphogenesis of embryonic epithelium GO:0016331 4 0.037
tube closure GO:0060606 3 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
regulation of keratinocyte migration GO:0051547 4 0.037
response to wounding GO:0009611 168 0.037
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.037
cation homeostasis GO:0055080 189 0.037
regulation of protein localization GO:0032880 296 0.037
cellular response to lipid GO:0071396 127 0.037
positive regulation of protein transport GO:0051222 135 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.036
skin development GO:0043588 76 0.036
steroid metabolic process GO:0008202 94 0.036
embryonic placenta development GO:0001892 1 0.036
establishment of protein localization to membrane GO:0090150 121 0.036
organic hydroxy compound metabolic process GO:1901615 147 0.036
receptor metabolic process GO:0043112 81 0.035
nephron morphogenesis GO:0072028 15 0.035
negative regulation of transport GO:0051051 176 0.035
regulation of neurogenesis GO:0050767 82 0.035
ion homeostasis GO:0050801 230 0.035
positive regulation of cytokine production GO:0001819 167 0.035
organ formation GO:0048645 3 0.035
single organism reproductive process GO:0044702 98 0.035
oogenesis GO:0048477 2 0.035
microtubule based process GO:0007017 210 0.035
cellular response to cytokine stimulus GO:0071345 181 0.035
positive regulation of nucleotide metabolic process GO:0045981 230 0.035
regulation of kinase activity GO:0043549 314 0.034
protein catabolic process GO:0030163 325 0.034
positive regulation of secretion GO:0051047 116 0.034
positive regulation of bmp signaling pathway GO:0030513 9 0.034
establishment of protein localization to organelle GO:0072594 172 0.034
determination of adult lifespan GO:0008340 2 0.034
lens development in camera type eye GO:0002088 2 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
neuron development GO:0048666 113 0.033
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
endoderm development GO:0007492 33 0.033
regulation of epithelial cell proliferation GO:0050678 113 0.033
response to cytokine GO:0034097 232 0.033
cellular homeostasis GO:0019725 196 0.032
positive regulation of osteoblast differentiation GO:0045669 23 0.032
regulation of response to external stimulus GO:0032101 222 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
cellular chemical homeostasis GO:0055082 180 0.032
positive regulation of catabolic process GO:0009896 310 0.032
negative regulation of programmed cell death GO:0043069 321 0.032
positive regulation of cellular component biogenesis GO:0044089 158 0.032
reactive oxygen species metabolic process GO:0072593 75 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
sequestering of calcium ion GO:0051208 17 0.031
regulation of intracellular transport GO:0032386 195 0.031
maintenance of location GO:0051235 112 0.031
regulation of neuron differentiation GO:0045664 70 0.031
positive regulation of epithelial cell migration GO:0010634 55 0.031
vesicle mediated transport GO:0016192 371 0.031
alcohol metabolic process GO:0006066 114 0.031
positive regulation of wnt signaling pathway GO:0030177 54 0.031
positive regulation of response to external stimulus GO:0032103 88 0.031
forelimb morphogenesis GO:0035136 4 0.031
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.031
regulation of protein complex assembly GO:0043254 147 0.031
cell projection organization GO:0030030 252 0.030
limbic system development GO:0021761 3 0.030
neural tube closure GO:0001843 3 0.030
endosomal transport GO:0016197 129 0.030
regulation of ion transport GO:0043269 189 0.029
protein localization to organelle GO:0033365 280 0.029
muscle cell fate commitment GO:0042693 4 0.029
regulation of endopeptidase activity GO:0052548 170 0.029
signal transduction by phosphorylation GO:0023014 297 0.028
cellular calcium ion homeostasis GO:0006874 117 0.028
inorganic ion transmembrane transport GO:0098660 231 0.028
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.028
regulation of activin receptor signaling pathway GO:0032925 14 0.028
positive regulation of aldosterone metabolic process GO:0032346 2 0.028
protein modification by small protein conjugation GO:0032446 342 0.028
ventricular septum morphogenesis GO:0060412 3 0.028
negative regulation of cellular component movement GO:0051271 106 0.028
sequestering of metal ion GO:0051238 24 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
protein targeting GO:0006605 187 0.028
regulation of cysteine type endopeptidase activity GO:2000116 127 0.028
mesonephric tubule development GO:0072164 14 0.028
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.028
metencephalon development GO:0022037 2 0.028
regulation of nucleocytoplasmic transport GO:0046822 98 0.027
forebrain neuron differentiation GO:0021879 3 0.027
cellular lipid metabolic process GO:0044255 303 0.027
organophosphate biosynthetic process GO:0090407 163 0.027
divalent inorganic cation homeostasis GO:0072507 136 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
oocyte differentiation GO:0009994 2 0.027
muscle tissue development GO:0060537 62 0.027
negative regulation of gliogenesis GO:0014014 3 0.026
inner ear morphogenesis GO:0042472 4 0.026
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.026
regulation of protein kinase activity GO:0045859 289 0.026
calcium ion transport into cytosol GO:0060402 48 0.026
multi organism cellular process GO:0044764 156 0.026
cellular response to hormone stimulus GO:0032870 125 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
actin filament based process GO:0030029 224 0.025
epithelial tube morphogenesis GO:0060562 38 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.025
regulation of nervous system development GO:0051960 88 0.025
epithelial cell proliferation GO:0050673 128 0.025
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.025
transmembrane transport GO:0055085 399 0.025
regulation of protein catabolic process GO:0042176 155 0.025
ion transmembrane transport GO:0034220 338 0.025
inositol lipid mediated signaling GO:0048017 55 0.025
regulation of epithelial to mesenchymal transition GO:0010717 37 0.025
nephron development GO:0072006 30 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
positive regulation of kinase activity GO:0033674 204 0.024
cell matrix adhesion GO:0007160 85 0.024
blastoderm segmentation GO:0007350 2 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.024
gland development GO:0048732 48 0.024
ureteric bud development GO:0001657 13 0.024
negative regulation of organelle organization GO:0010639 126 0.024
regulation of defense response GO:0031347 154 0.024
positive regulation of organelle organization GO:0010638 195 0.024
endothelial cell migration GO:0043542 86 0.024
renal tubule development GO:0061326 19 0.024
blastocyst formation GO:0001825 3 0.024
negative regulation of protein phosphorylation GO:0001933 140 0.024
protein oligomerization GO:0051259 173 0.024
cranial nerve morphogenesis GO:0021602 1 0.024
pituitary gland development GO:0021983 2 0.024
forebrain development GO:0030900 26 0.024
positive regulation of transferase activity GO:0051347 227 0.024
heart morphogenesis GO:0003007 48 0.023
cell part morphogenesis GO:0032990 137 0.023
positive regulation of map kinase activity GO:0043406 80 0.023
endocrine system development GO:0035270 26 0.023
oocyte development GO:0048599 1 0.023
organic hydroxy compound biosynthetic process GO:1901617 71 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
regulation of cell substrate adhesion GO:0010810 68 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
cardiac muscle tissue development GO:0048738 39 0.023
protein localization to plasma membrane GO:0072659 93 0.023
nucleocytoplasmic transport GO:0006913 176 0.023
cell projection morphogenesis GO:0048858 129 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
positive regulation of cell adhesion GO:0045785 84 0.023
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
response to bacterium GO:0009617 144 0.022
protein localization to membrane GO:0072657 160 0.022
endoderm formation GO:0001706 33 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
cellular protein complex assembly GO:0043623 188 0.022
regulation of metal ion transport GO:0010959 120 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
inorganic cation transmembrane transport GO:0098662 194 0.022
ureteric bud morphogenesis GO:0060675 10 0.022
embryonic forelimb morphogenesis GO:0035115 4 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
regulation of lipid metabolic process GO:0019216 96 0.022
spinal cord development GO:0021510 4 0.022
locomotory behavior GO:0007626 1 0.022
cell division GO:0051301 168 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.022
lipid transport GO:0006869 90 0.022
cellular hormone metabolic process GO:0034754 41 0.022
retinal ganglion cell axon guidance GO:0031290 2 0.022
response to oxygen levels GO:0070482 100 0.021
regulation of purine nucleotide catabolic process GO:0033121 205 0.021
activation of protein kinase activity GO:0032147 90 0.021
bone development GO:0060348 26 0.021
skeletal system morphogenesis GO:0048705 24 0.021
dna repair GO:0006281 198 0.021
hair cycle GO:0042633 28 0.021
interspecies interaction between organisms GO:0044419 156 0.021
mesonephric epithelium development GO:0072163 14 0.021
keratinocyte differentiation GO:0030216 36 0.021
cytosolic calcium ion homeostasis GO:0051480 89 0.021
embryonic camera type eye development GO:0031076 2 0.021
wound healing GO:0042060 115 0.021
cellular ion homeostasis GO:0006873 168 0.021
cell type specific apoptotic process GO:0097285 125 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
developmental programmed cell death GO:0010623 3 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
dephosphorylation GO:0016311 209 0.021
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 18 0.021
positive regulation of secretion by cell GO:1903532 108 0.021
positive regulation of gtp catabolic process GO:0033126 166 0.021
reproductive system development GO:0061458 56 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
negative regulation of kidney development GO:0090185 2 0.020
membrane organization GO:0061024 292 0.020
phosphatidylinositol mediated signaling GO:0048015 55 0.020
cytokine mediated signaling pathway GO:0019221 109 0.020
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.020
androgen receptor signaling pathway GO:0030521 34 0.020
cell migration involved in gastrulation GO:0042074 1 0.020
limb development GO:0060173 23 0.020
regeneration GO:0031099 4 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
actin cytoskeleton organization GO:0030036 207 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
cell proliferation in forebrain GO:0021846 1 0.020
cell chemotaxis GO:0060326 112 0.020
positive regulation of jnk cascade GO:0046330 52 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
purine ribonucleotide biosynthetic process GO:0009152 79 0.020
regulation of dna binding GO:0051101 37 0.019
signal release GO:0023061 70 0.019
positive regulation of immune system process GO:0002684 283 0.019
mesonephric tubule morphogenesis GO:0072171 10 0.019
amide transport GO:0042886 76 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
axis elongation GO:0003401 4 0.019
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
negative regulation of cell motility GO:2000146 104 0.019
carbohydrate metabolic process GO:0005975 207 0.019
hair follicle morphogenesis GO:0031069 2 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
ketone biosynthetic process GO:0042181 17 0.019
divalent inorganic cation transport GO:0072511 158 0.019
protein localization to nucleus GO:0034504 136 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
thymus development GO:0048538 3 0.019
behavior GO:0007610 112 0.019
negative regulation of binding GO:0051100 57 0.019
single organism membrane organization GO:0044802 268 0.019
protein maturation GO:0051604 233 0.019
intrinsic apoptotic signaling pathway GO:0097193 127 0.019
stress activated mapk cascade GO:0051403 93 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
regulation of ion homeostasis GO:2000021 73 0.018
plasma membrane organization GO:0007009 115 0.018
regulation of response to wounding GO:1903034 101 0.018
cellular component disassembly GO:0022411 92 0.018
organophosphate catabolic process GO:0046434 430 0.018
lung alveolus development GO:0048286 4 0.018

PAPPA disease predictions

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 88 0.047
musculoskeletal system disease DOID:17 223 0.047
connective tissue disease DOID:65 109 0.047