Homo sapiens

15 known processes

SMG5

Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)

(Aliases: SMG-5,LPTSRP1,FLJ12287,FLJ34864,EST1B,LPTS-RP1,KIAA1089)

SMG5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 175 0.459
Human
rna catabolic process GO:0006401 71 0.243
Human
purine ribonucleoside catabolic process GO:0046130 398 0.211
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.161
ribonucleoside triphosphate catabolic process GO:0009203 391 0.154
intracellular mrna localization GO:0008298 1 0.150
mrna catabolic process GO:0006402 56 0.116
Human
nucleotide catabolic process GO:0009166 408 0.095
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.092
purine nucleoside triphosphate metabolic process GO:0009144 412 0.090
purine containing compound catabolic process GO:0072523 411 0.089
nucleoside catabolic process GO:0009164 408 0.087
ribonucleotide catabolic process GO:0009261 405 0.086
purine nucleoside catabolic process GO:0006152 398 0.083
organophosphate catabolic process GO:0046434 430 0.083
rna processing GO:0006396 255 0.081
purine nucleoside triphosphate catabolic process GO:0009146 392 0.081
nucleoside triphosphate catabolic process GO:0009143 394 0.079
glycosyl compound catabolic process GO:1901658 413 0.079
nucleoside phosphate catabolic process GO:1901292 412 0.078
post embryonic development GO:0009791 2 0.078
purine ribonucleotide catabolic process GO:0009154 404 0.075
purine nucleotide catabolic process GO:0006195 405 0.066
dna recombination GO:0006310 77 0.062
ribonucleoside catabolic process GO:0042454 406 0.059
single organism cellular localization GO:1902580 332 0.059
ribonucleoside triphosphate metabolic process GO:0009199 412 0.057
protein ubiquitination GO:0016567 314 0.055
posttranscriptional regulation of gene expression GO:0010608 213 0.054
protein modification by small protein conjugation GO:0032446 342 0.050
ras protein signal transduction GO:0007265 73 0.049
mrna processing GO:0006397 133 0.049
purine ribonucleoside metabolic process GO:0046128 437 0.046
small gtpase mediated signal transduction GO:0007264 78 0.045
regulation of cell cycle GO:0051726 393 0.044
multicellular organismal aging GO:0010259 3 0.044
secretion by cell GO:0032940 226 0.043
cytoplasmic transport GO:0016482 379 0.043
covalent chromatin modification GO:0016569 254 0.041
rna interference GO:0016246 4 0.041
positive regulation of catabolic process GO:0009896 310 0.039
gtp metabolic process GO:0046039 239 0.038
determination of adult lifespan GO:0008340 2 0.038
dna repair GO:0006281 198 0.036
locomotory behavior GO:0007626 1 0.033
chromatin modification GO:0016568 298 0.032
single organism membrane organization GO:0044802 268 0.032
blastoderm segmentation GO:0007350 2 0.031
cellular response to dna damage stimulus GO:0006974 379 0.031
oogenesis GO:0048477 2 0.031
nucleoside monophosphate catabolic process GO:0009125 159 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
segmentation GO:0035282 4 0.030
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
protein acylation GO:0043543 138 0.029
purine nucleoside monophosphate catabolic process GO:0009128 158 0.028
negative regulation of programmed cell death GO:0043069 321 0.028
response to fungus GO:0009620 4 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.027
cellular ketone metabolic process GO:0042180 80 0.027
protein localization to organelle GO:0033365 280 0.026
actin filament based process GO:0030029 224 0.026
guanosine containing compound metabolic process GO:1901068 244 0.026
oocyte development GO:0048599 1 0.025
atp metabolic process GO:0046034 176 0.025
intracellular protein transport GO:0006886 270 0.025
histone modification GO:0016570 251 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
myosin filament assembly GO:0031034 2 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
positive regulation of nucleotide catabolic process GO:0030813 185 0.024
female gamete generation GO:0007292 2 0.024
nucleoside monophosphate metabolic process GO:0009123 191 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
spermatid development GO:0007286 4 0.023
regulation of translation GO:0006417 89 0.023
immune system development GO:0002520 195 0.022
defense response GO:0006952 315 0.022
anterior posterior axis specification GO:0009948 2 0.022
immune response GO:0006955 307 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
negative regulation of cell death GO:0060548 345 0.021
dna replication GO:0006260 116 0.021
response to oxygen containing compound GO:1901700 369 0.021
protein targeting GO:0006605 187 0.021
cellular protein complex assembly GO:0043623 188 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
mitotic cell cycle process GO:1903047 286 0.021
glycerolipid metabolic process GO:0046486 107 0.020
protein acetylation GO:0006473 116 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
regulation of gtpase activity GO:0043087 180 0.019
peptidyl lysine modification GO:0018205 144 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
histone acetylation GO:0016573 93 0.019
demethylation GO:0070988 37 0.019
response to decreased oxygen levels GO:0036293 96 0.019
regulation of secretion by cell GO:1903530 177 0.019
nitrogen compound transport GO:0071705 191 0.019
peptidyl lysine acetylation GO:0018394 101 0.018
positive regulation of gtpase activity GO:0043547 166 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
system process GO:0003008 349 0.018
regulation of dna metabolic process GO:0051052 153 0.018
gene silencing GO:0016458 49 0.018
positive regulation of cell death GO:0010942 263 0.018
oocyte differentiation GO:0009994 2 0.018
anterior posterior axis specification embryo GO:0008595 2 0.018
cellular amino acid metabolic process GO:0006520 116 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
Human
internal peptidyl lysine acetylation GO:0018393 97 0.017
actin cytoskeleton organization GO:0030036 207 0.017
cellular amine metabolic process GO:0044106 41 0.017
gtp catabolic process GO:0006184 237 0.017
response to nitrogen compound GO:1901698 184 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
innate immune response GO:0045087 178 0.016
protein localization to membrane GO:0072657 160 0.016
dna conformation change GO:0071103 113 0.016
embryo development GO:0009790 123 0.016
mitotic cell cycle GO:0000278 326 0.016
secretion GO:0046903 254 0.016
spermatid differentiation GO:0048515 4 0.016
chemical homeostasis GO:0048878 306 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
adult locomotory behavior GO:0008344 1 0.015
chromatin organization GO:0006325 351 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
cellular component disassembly GO:0022411 92 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
amine metabolic process GO:0009308 44 0.015
regulation of cell differentiation GO:0045595 393 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
rna splicing via transesterification reactions GO:0000375 90 0.015
growth GO:0040007 202 0.015
regulation of hormone levels GO:0010817 125 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
circadian behavior GO:0048512 2 0.014
rna splicing GO:0008380 131 0.014
membrane organization GO:0061024 292 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
small molecule biosynthetic process GO:0044283 157 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
apoptotic signaling pathway GO:0097190 268 0.014
regulation of growth GO:0040008 165 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
regulation of peptidase activity GO:0052547 180 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
tripartite regional subdivision GO:0007351 2 0.014
cell cell signaling GO:0007267 155 0.013
regulation of cholesterol metabolic process GO:0090181 4 0.013
maintenance of location GO:0051235 112 0.013
cell growth GO:0016049 160 0.013
positive regulation of transferase activity GO:0051347 227 0.013
cellular lipid metabolic process GO:0044255 303 0.013
anatomical structure homeostasis GO:0060249 100 0.013
Human
dephosphorylation GO:0016311 209 0.013
neuromuscular junction development GO:0007528 3 0.013
ncrna metabolic process GO:0034660 108 0.013
lipid metabolic process GO:0006629 381 0.012
dna packaging GO:0006323 77 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.012
response to abiotic stimulus GO:0009628 336 0.012
single organism reproductive process GO:0044702 98 0.012
protein catabolic process GO:0030163 325 0.012
hemopoiesis GO:0030097 180 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
sleep GO:0030431 2 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
epithelium development GO:0060429 227 0.012
cellular homeostasis GO:0019725 196 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
g2 m transition of mitotic cell cycle GO:0000086 41 0.011
histone mrna catabolic process GO:0071044 10 0.011
myosin filament organization GO:0031033 2 0.011
neurological system process GO:0050877 163 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of mrna processing GO:0050684 48 0.011
otic vesicle development GO:0071599 1 0.011
convergent extension GO:0060026 1 0.011
nervous system development GO:0007399 293 0.011
protein oligomerization GO:0051259 173 0.011
cell cycle g2 m phase transition GO:0044839 43 0.011
negative regulation of protein modification process GO:0031400 200 0.011
response to nitric oxide GO:0071731 4 0.011
cell development GO:0048468 328 0.011
macroautophagy GO:0016236 39 0.011
neurogenesis GO:0022008 169 0.011
rhythmic behavior GO:0007622 2 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
embryonic organ development GO:0048568 36 0.011
regulation of protein localization GO:0032880 296 0.011
protein homooligomerization GO:0051260 100 0.011
cellular response to external stimulus GO:0071496 111 0.011
regulation of establishment of protein localization GO:0070201 242 0.010
muscle cell differentiation GO:0042692 63 0.010
regulation of mrna metabolic process GO:1903311 53 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
regulation of intracellular transport GO:0032386 195 0.010
negative regulation of developmental process GO:0051093 247 0.010

SMG5 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.056
disease of cellular proliferation DOID:14566 174 0.056
organ system cancer DOID:0050686 164 0.038
musculoskeletal system disease DOID:17 223 0.019