|
|
negative regulation of calcidiol 1 monooxygenase activity
|
GO:0010956 |
3 |
1.000
|
Human |
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
1.000
|
Fly |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
1.000
|
Human |
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
1.000
|
Fly |
|
|
positive regulation of hyaluronan biosynthetic process
|
GO:1900127 |
3 |
0.999
|
Human |
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
0.998
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.998
|
Human |
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
8 |
0.993
|
Human |
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.993
|
Human |
|
|
negative regulation of vitamin metabolic process
|
GO:0046137 |
6 |
0.992
|
Human |
|
|
positive regulation of cholesterol efflux
|
GO:0010875 |
8 |
0.989
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.985
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.983
|
Fly |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.983
|
Fly |
|
|
sterol transport
|
GO:0015918 |
39 |
0.979
|
|
|
|
regulation of sterol transport
|
GO:0032371 |
21 |
0.979
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
5 |
0.973
|
Human |
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
11 |
0.966
|
Human |
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.962
|
Human |
|
|
cholesterol efflux
|
GO:0033344 |
28 |
0.959
|
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.955
|
Human |
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.947
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
6 |
0.947
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.938
|
|
|
|
cellular response to nicotine
|
GO:0071316 |
4 |
0.930
|
Human |
|
|
spleen development
|
GO:0048536 |
1 |
0.929
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.915
|
Human |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.909
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.903
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.900
|
Human |
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.900
|
Human |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.900
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.900
|
Human Fly |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.897
|
Fly |
|
|
regulation of lipid storage
|
GO:0010883 |
21 |
0.888
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.885
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.880
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.879
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.878
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.877
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.862
|
Human |
|
|
antifungal humoral response
|
GO:0019732 |
2 |
0.861
|
Fly |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.853
|
Human |
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.852
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
24 |
0.831
|
Fly |
|
|
negative regulation of vitamin d biosynthetic process
|
GO:0010957 |
5 |
0.826
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.822
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.807
|
Human |
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.802
|
Human |
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.797
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.790
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.782
|
Human |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.776
|
Human |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.766
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.766
|
Human |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.760
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.755
|
Human |
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.749
|
|
|
|
regulation of cholesterol transport
|
GO:0032374 |
21 |
0.749
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.745
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.740
|
Human Fly |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.738
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.729
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.728
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.721
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.712
|
|
|
|
response to uv b
|
GO:0010224 |
10 |
0.695
|
Human |
|
|
regulation of interleukin 8 biosynthetic process
|
GO:0045414 |
11 |
0.692
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.691
|
Human Fly |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.686
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.683
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.682
|
Human Fly |
|
|
response to fungus
|
GO:0009620 |
4 |
0.679
|
Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.677
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.676
|
Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.676
|
Human Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.675
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.673
|
Human |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.663
|
Human |
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.658
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.656
|
Human |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.651
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.650
|
Fly |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.640
|
Mouse |
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.635
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.634
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.624
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.608
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.606
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.605
|
Human Fly |
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
13 |
0.604
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.604
|
Fly |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.598
|
Human |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.597
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.597
|
Human |
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.596
|
Human |
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.590
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.589
|
Human |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.556
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.553
|
Human |
|
|
regulation of macrophage derived foam cell differentiation
|
GO:0010743 |
14 |
0.544
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.543
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.539
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.533
|
Human |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.529
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.523
|
Human |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.520
|
Human |
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.515
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.512
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.506
|
Human |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.502
|
Human Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.497
|
Human |
|
|
response to uv
|
GO:0009411 |
73 |
0.486
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.480
|
Human |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.475
|
|
|
|
vitamin biosynthetic process
|
GO:0009110 |
11 |
0.473
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.466
|
Human |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.464
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.452
|
Human Fly |
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.449
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.437
|
Fly |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.436
|
Human Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.434
|
Human Fly |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.433
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.428
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.419
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.418
|
Human |
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.416
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.413
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.412
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.412
|
|
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
18 |
0.409
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.398
|
Human |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.390
|
Human |
|
|
neutral amino acid transport
|
GO:0015804 |
9 |
0.380
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.378
|
Fly |
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.378
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.375
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.372
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.372
|
Human |
|
|
muscle system process
|
GO:0003012 |
81 |
0.371
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.368
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.364
|
Fly |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.364
|
Human |
|
|
peptide biosynthetic process
|
GO:0043043 |
8 |
0.356
|
Fly |
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.353
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.350
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.342
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.337
|
Fly |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.331
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.328
|
Human Fly |
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.326
|
Human |
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.325
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.324
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
9 |
0.321
|
Human |
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.315
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.285
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.282
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.279
|
Human |
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.275
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
12 |
0.273
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.268
|
|
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.267
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.266
|
Fly |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.263
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.259
|
Human |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.256
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.256
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.255
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.251
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.249
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.247
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.246
|
Human |
|
|
regulation of mirna metabolic process
|
GO:2000628 |
5 |
0.244
|
Human |
|
|
mature b cell differentiation
|
GO:0002335 |
1 |
0.242
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.242
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
12 |
0.240
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.238
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.237
|
Human |
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.237
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.237
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.234
|
|
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
4 |
0.231
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.223
|
Human |
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.222
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.221
|
Human |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.221
|
Human |
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.219
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.217
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
39 |
0.216
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.216
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.214
|
Fly |
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.214
|
Human |
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
1 |
0.213
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.213
|
Human |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.213
|
Human |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.209
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.208
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
27 |
0.207
|
Human |
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.205
|
Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.204
|
|
|
|
negative regulation of macrophage derived foam cell differentiation
|
GO:0010745 |
7 |
0.198
|
|
|
|
hyaluronan metabolic process
|
GO:0030212 |
15 |
0.196
|
Human |
|
|
aortic valve development
|
GO:0003176 |
3 |
0.192
|
|
|
|
regulation of hyaluronan biosynthetic process
|
GO:1900125 |
6 |
0.192
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.191
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.186
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.184
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.184
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.184
|
Human |
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.184
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
22 |
0.182
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.181
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.181
|
|
|
|
response to exogenous dsrna
|
GO:0043330 |
10 |
0.180
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.179
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.179
|
Fly |
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.178
|
Human |
|
|
response to dsrna
|
GO:0043331 |
25 |
0.176
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.175
|
Mouse |
|
|
regulation of translation
|
GO:0006417 |
89 |
0.175
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.174
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.174
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.173
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.170
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
1 |
0.162
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
35 |
0.162
|
Human |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.161
|
Human |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.159
|
Human |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.156
|
Human |
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.156
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.154
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.151
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.149
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.149
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.147
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.145
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.143
|
Human |
|
|
lipid localization
|
GO:0010876 |
106 |
0.141
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.141
|
Human |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.139
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.139
|
Fly |
|
|
negative regulation of oxidoreductase activity
|
GO:0051354 |
17 |
0.138
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.137
|
Fly |
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.137
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
9 |
0.135
|
Human |
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.133
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.132
|
Human |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.131
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.131
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.128
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.127
|
Human |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.125
|
Human |
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.124
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.124
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.123
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.117
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.116
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.116
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.115
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.114
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.114
|
|
|
|
regulation of calcidiol 1 monooxygenase activity
|
GO:0060558 |
6 |
0.114
|
Human |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.112
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.111
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
10 |
0.110
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.110
|
Human |
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.109
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.107
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.105
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.101
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.100
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.100
|
Human |
|
|
serine transport
|
GO:0032329 |
1 |
0.100
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.097
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.096
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.092
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.092
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.090
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.090
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.089
|
|
|
|
interleukin 8 biosynthetic process
|
GO:0042228 |
12 |
0.089
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
8 |
0.088
|
|
|
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.087
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.087
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.087
|
Human Fly |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.087
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.087
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.084
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.084
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.084
|
Human |
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
21 |
0.083
|
Human |
|
|
positive regulation of sterol transport
|
GO:0032373 |
10 |
0.083
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
7 |
0.081
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.081
|
Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.080
|
Human |
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.078
|
|
|
|
response to nicotine
|
GO:0035094 |
12 |
0.078
|
Human |
|
|
response to virus
|
GO:0009615 |
126 |
0.077
|
|
|
|
disruption of cells of other organism involved in symbiotic interaction
|
GO:0051818 |
3 |
0.077
|
|
|
|
negative regulation of monooxygenase activity
|
GO:0032769 |
7 |
0.076
|
Human |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.074
|
|
|
|
regulation of cholesterol efflux
|
GO:0010874 |
11 |
0.074
|
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
15 |
0.074
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.074
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.073
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.073
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.072
|
Human |
|
|
associative learning
|
GO:0008306 |
1 |
0.069
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.069
|
Human |
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.068
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.067
|
|
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
21 |
0.066
|
Human |
|
|
organic acid transport
|
GO:0015849 |
65 |
0.066
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.065
|
Human |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.065
|
Human |
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.065
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.064
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.063
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.063
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.063
|
Human |
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.061
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.059
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.058
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.058
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.057
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.056
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.055
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.055
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.055
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.055
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.054
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.054
|
Human |
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.053
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
9 |
0.052
|
Fly |
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.052
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.052
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.052
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.051
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.051
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.051
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.051
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.051
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.050
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.050
|
Human |
|
|
acute phase response
|
GO:0006953 |
5 |
0.049
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.049
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.049
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
10 |
0.048
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.048
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.045
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.044
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.044
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.044
|
Human |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.044
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.044
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.044
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.043
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.043
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.043
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.043
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.043
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.043
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.043
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.043
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.043
|
Fly |
|
|
hair cycle
|
GO:0042633 |
28 |
0.042
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.042
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.041
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.041
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.040
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.040
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.040
|
|
|
|
amino acid transport
|
GO:0006865 |
28 |
0.040
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.040
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.039
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.038
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.038
|
Fly |
|
|
translation
|
GO:0006412 |
132 |
0.037
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.037
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.037
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.037
|
Human |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.037
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.036
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.036
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.036
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.036
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.035
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.035
|
Fly |
|
|
cardiac conduction system development
|
GO:0003161 |
2 |
0.035
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.035
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.035
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.035
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.034
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.034
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.034
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.034
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.034
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
1 |
0.033
|
Mouse |
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.033
|
Human |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.033
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.033
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.033
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
5 |
0.033
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.033
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
10 |
0.032
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.032
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.032
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.032
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.031
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.031
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
11 |
0.031
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.031
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.031
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.030
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.030
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.029
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.029
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.029
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.028
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.028
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.027
|
Human |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.027
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.027
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.027
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.027
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.026
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.026
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.026
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.025
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.025
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.025
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.025
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.025
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.025
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.025
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.025
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.024
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.024
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.024
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
2 |
0.024
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.024
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.024
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.024
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.024
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.023
|
|
|
|
d amino acid transport
|
GO:0042940 |
3 |
0.023
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.023
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.023
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.023
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.022
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.022
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.022
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.022
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.022
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.022
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.022
|
|
|
|
toll like receptor 3 signaling pathway
|
GO:0034138 |
4 |
0.022
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.022
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.021
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.021
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.021
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.021
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.021
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.021
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.021
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.021
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.020
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.020
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.020
|
|
|
|
hyaluronan biosynthetic process
|
GO:0030213 |
10 |
0.020
|
Human |
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.020
|
|
|
|
positive regulation of cell fate specification
|
GO:0042660 |
2 |
0.020
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.020
|
|
|
|
venous blood vessel development
|
GO:0060841 |
2 |
0.020
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.020
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.020
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.019
|
|
|
|
negative regulation of chromatin silencing at rdna
|
GO:0061188 |
2 |
0.019
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.019
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.019
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.019
|
Fly |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.019
|
|
