|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.982
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.981
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.981
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.980
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.974
|
|
|
positive regulation of nik nf kappab signaling
|
GO:1901224 |
10 |
0.965
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.962
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.955
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.944
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.898
|
|
|
positive regulation of interleukin 8 biosynthetic process
|
GO:0045416 |
8 |
0.895
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.865
|
Mouse |
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.848
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.846
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.844
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.835
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.812
|
Mouse |
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.811
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.806
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.789
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.787
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.767
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.748
|
Mouse |
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.746
|
|
|
positive regulation of t cell cytokine production
|
GO:0002726 |
4 |
0.691
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.687
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.683
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.681
|
Mouse |
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.644
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.640
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.633
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.632
|
|
|
cellular defense response
|
GO:0006968 |
2 |
0.630
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.610
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.603
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.570
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.563
|
Mouse |
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.521
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.507
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.494
|
Mouse |
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.489
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.486
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.481
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.480
|
Mouse |
|
regulation of protein localization
|
GO:0032880 |
296 |
0.470
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.468
|
Mouse |
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.452
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.448
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.447
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.426
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.423
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.411
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.399
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.394
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.389
|
|
|
immunoglobulin secretion
|
GO:0048305 |
1 |
0.385
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.380
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.368
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.368
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.360
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.358
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.358
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.353
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.352
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.349
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.343
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.338
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.332
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.327
|
Mouse |
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.319
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.315
|
Mouse |
|
t cell activation
|
GO:0042110 |
99 |
0.313
|
Mouse |
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.311
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.310
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.309
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.306
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.301
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.298
|
Mouse |
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.295
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.292
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.291
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.289
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ii
|
GO:0019886 |
4 |
0.288
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.286
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.283
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.281
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.275
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.275
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.267
|
|
|
defense response
|
GO:0006952 |
315 |
0.265
|
Mouse |
|
response to bacterium
|
GO:0009617 |
144 |
0.259
|
Mouse |
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.259
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.256
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.255
|
Mouse |
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.255
|
|
|
cell activation
|
GO:0001775 |
213 |
0.254
|
Mouse |
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.253
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.246
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.244
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.244
|
Mouse |
|
adaptive immune response
|
GO:0002250 |
49 |
0.243
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.243
|
|
|
tube development
|
GO:0035295 |
125 |
0.238
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.234
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.232
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.227
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.227
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.224
|
|
|
autophagy
|
GO:0006914 |
88 |
0.220
|
|
|
dna repair
|
GO:0006281 |
198 |
0.209
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.208
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.205
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.203
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.201
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.200
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.194
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.192
|
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.192
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.186
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.185
|
Mouse |
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.184
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.183
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.182
|
Mouse |
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.182
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.179
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.173
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.172
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.170
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.170
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.169
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.168
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.168
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.166
|
Mouse |
|
regulation of cell motility
|
GO:2000145 |
299 |
0.166
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.164
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.163
|
|
|
immune response
|
GO:0006955 |
307 |
0.163
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.162
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.160
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.156
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.154
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.153
|
|
|
rna processing
|
GO:0006396 |
255 |
0.146
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.145
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.145
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.144
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.143
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.142
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.141
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.140
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.138
|
Mouse |
|
regulation of necrotic cell death
|
GO:0010939 |
9 |
0.136
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.134
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.132
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.131
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.130
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.129
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.126
|
|
|
response to virus
|
GO:0009615 |
126 |
0.126
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.125
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.125
|
|
|
immune system development
|
GO:0002520 |
195 |
0.124
|
Mouse |
|
lipid metabolic process
|
GO:0006629 |
381 |
0.123
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.123
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.123
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.122
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.122
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.122
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.120
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.119
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.118
|
Mouse |
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.116
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.114
|
|
|
protein import
|
GO:0017038 |
130 |
0.114
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.113
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.112
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.112
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.111
|
|
|
tube closure
|
GO:0060606 |
3 |
0.111
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.109
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.109
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.109
|
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.108
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.108
|
|
|
secretion
|
GO:0046903 |
254 |
0.108
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.106
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.106
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.105
|
|
|
cell development
|
GO:0048468 |
328 |
0.104
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.104
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.104
|
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.104
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.103
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.101
|
|
|
system process
|
GO:0003008 |
349 |
0.100
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.100
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.099
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.098
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.095
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.095
|
|
|
protein processing
|
GO:0016485 |
226 |
0.094
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.094
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.093
|
|
|
embryo development
|
GO:0009790 |
123 |
0.093
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.092
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
11 |
0.092
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.090
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.090
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.090
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.089
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.086
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.086
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.085
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.085
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.084
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.084
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.084
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.084
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.083
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.083
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.081
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.081
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.081
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.081
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.080
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.080
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.080
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.080
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.080
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.079
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.078
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.078
|
|
|
cell division
|
GO:0051301 |
168 |
0.077
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
1 |
0.077
|
|
|
regulation of cd40 signaling pathway
|
GO:2000348 |
3 |
0.076
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.075
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.074
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.074
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.074
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.074
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.073
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.072
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.072
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.072
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.071
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.071
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.071
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.070
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.070
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.069
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.069
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.068
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.067
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.065
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.065
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.063
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
5 |
0.063
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.061
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.061
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.060
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.060
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.059
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.059
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.059
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.058
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.058
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.058
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.058
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.058
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.058
|
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
11 |
0.058
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.056
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.056
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.056
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.056
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.056
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.056
|
|
|
histone modification
|
GO:0016570 |
251 |
0.056
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.056
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.056
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.056
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.056
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.055
|
Mouse |
|
thymic t cell selection
|
GO:0045061 |
2 |
0.055
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.055
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.054
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.054
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.054
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.054
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.053
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.053
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.053
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.053
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.053
|
|
|
organic acid catabolic process
|
GO:0016054 |
71 |
0.052
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.052
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.052
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.051
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.051
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.051
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.050
|
Mouse |
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.050
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.050
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.049
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.049
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.049
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.049
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.048
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.048
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.048
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.047
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.047
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.047
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.046
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.046
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.046
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.046
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.046
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.046
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.045
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.045
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.045
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.045
|
|
|
segmentation
|
GO:0035282 |
4 |
0.045
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
8 |
0.045
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.045
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.045
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.045
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.044
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.044
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.044
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.044
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.044
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.043
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.043
|
|
|
heart development
|
GO:0007507 |
95 |
0.043
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.043
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.043
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.042
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.041
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.041
|
|
|
epithelial tube formation
|
GO:0072175 |
5 |
0.041
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.041
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.041
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.041
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.041
|
|
|
growth
|
GO:0040007 |
202 |
0.040
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.040
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.040
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.040
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.040
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.039
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.039
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.039
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.038
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.038
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.038
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
5 |
0.038
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.038
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.038
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.037
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.037
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.037
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.037
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.037
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.036
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.036
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.036
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.036
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.036
|
|
|
tube formation
|
GO:0035148 |
10 |
0.035
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.035
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.035
|
|
|
regulation of t cell cytokine production
|
GO:0002724 |
10 |
0.035
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.035
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.035
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.035
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.035
|
|
|
regeneration
|
GO:0031099 |
4 |
0.035
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.035
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.034
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.034
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.034
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.034
|
|
|
negative regulation of b cell apoptotic process
|
GO:0002903 |
4 |
0.034
|
|
|
head development
|
GO:0060322 |
108 |
0.034
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
32 |
0.033
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.033
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.033
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.033
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.033
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.033
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.032
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.032
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.032
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.032
|
|
|
lipid oxidation
|
GO:0034440 |
33 |
0.032
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.032
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.032
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.032
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.032
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.031
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.031
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.031
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.031
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.031
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.031
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.031
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.031
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.031
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.031
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.031
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.030
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.030
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.030
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.030
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.030
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.030
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.030
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.029
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.029
|
|
|
cell aging
|
GO:0007569 |
52 |
0.029
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.029
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.029
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.029
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.029
|
|
|
anion transport
|
GO:0006820 |
161 |
0.029
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.029
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
9 |
0.029
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.029
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.028
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.028
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.028
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.028
|
|
|
necroptotic process
|
GO:0070266 |
16 |
0.028
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.028
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
5 |
0.028
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.028
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.028
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.028
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.028
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.028
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.028
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.027
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.027
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.027
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.027
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.027
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.027
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.027
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.027
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.027
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.027
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.027
|
|
|
regulation of sphingomyelin catabolic process
|
GO:2000754 |
1 |
0.027
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
38 |
0.027
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.027
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.027
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.027
|
|
|
positive regulation of superoxide anion generation
|
GO:0032930 |
4 |
0.027
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.026
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.026
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.026
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.026
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.026
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.025
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.025
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.025
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.025
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.025
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.025
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.025
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.025
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.024
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
Mouse |
|
taxis
|
GO:0042330 |
157 |
0.024
|
|
|
ossification
|
GO:0001503 |
121 |
0.024
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.024
|
|
|
lymphocyte costimulation
|
GO:0031294 |
7 |
0.024
|
|
|
t helper 1 type immune response
|
GO:0042088 |
8 |
0.024
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.024
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.024
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.024
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.024
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.024
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.024
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.024
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.024
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
11 |
0.024
|
|