Homo sapiens

16 known processes

TMEM123

transmembrane protein 123

(Aliases: KCT3,PORMIN,PORIMIN)

TMEM123 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mesonephric tubule formation GO:0072172 1 0.232
protein o linked glycosylation via serine GO:0018242 3 0.164
amine metabolic process GO:0009308 44 0.142
cellular lipid metabolic process GO:0044255 303 0.128
cellular amino acid metabolic process GO:0006520 116 0.125
cell adhesion GO:0007155 325 0.113
organophosphate biosynthetic process GO:0090407 163 0.104
small molecule biosynthetic process GO:0044283 157 0.102
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.101
carbohydrate derivative biosynthetic process GO:1901137 207 0.098
cellular ketone metabolic process GO:0042180 80 0.092
ribose phosphate biosynthetic process GO:0046390 82 0.084
glycosyl compound catabolic process GO:1901658 413 0.084
regulation of nucleotide metabolic process GO:0006140 269 0.083
organic anion transport GO:0015711 103 0.083
neuromuscular junction development GO:0007528 3 0.079
positive regulation of cellular amine metabolic process GO:0033240 7 0.077
regulation of cellular component movement GO:0051270 334 0.077
organophosphate catabolic process GO:0046434 430 0.075
embryonic epithelial tube formation GO:0001838 4 0.074
biological adhesion GO:0022610 331 0.073
ribonucleoside triphosphate metabolic process GO:0009199 412 0.072
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.072
nucleoside triphosphate metabolic process GO:0009141 422 0.069
nucleoside phosphate biosynthetic process GO:1901293 109 0.068
regulation of cellular amine metabolic process GO:0033238 11 0.066
ribonucleotide catabolic process GO:0009261 405 0.066
cellular amine metabolic process GO:0044106 41 0.066
ribonucleoside triphosphate catabolic process GO:0009203 391 0.063
cell projection organization GO:0030030 252 0.062
purine nucleoside triphosphate metabolic process GO:0009144 412 0.061
ribonucleotide biosynthetic process GO:0009260 81 0.058
positive regulation of developmental process GO:0051094 314 0.058
growth GO:0040007 202 0.058
regulation of cellular ketone metabolic process GO:0010565 50 0.057
carbohydrate metabolic process GO:0005975 207 0.057
single organism cell adhesion GO:0098602 179 0.057
morphogenesis of embryonic epithelium GO:0016331 4 0.056
ribonucleoside monophosphate metabolic process GO:0009161 187 0.055
regulation of cellular response to stress GO:0080135 244 0.055
regulation of nucleoside metabolic process GO:0009118 209 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.054
ion transmembrane transport GO:0034220 338 0.053
nucleoside triphosphate catabolic process GO:0009143 394 0.053
purine nucleotide catabolic process GO:0006195 405 0.053
nervous system development GO:0007399 293 0.052
single organism carbohydrate metabolic process GO:0044723 193 0.051
negative regulation of phosphorus metabolic process GO:0010563 267 0.050
atp metabolic process GO:0046034 176 0.048
cell activation GO:0001775 213 0.048
regulation of cellular amino acid metabolic process GO:0006521 6 0.047
actin filament based process GO:0030029 224 0.047
ribonucleoside catabolic process GO:0042454 406 0.047
single organism membrane organization GO:0044802 268 0.047
cytokine production GO:0001816 247 0.046
positive regulation of immune system process GO:0002684 283 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
skin development GO:0043588 76 0.045
regulation of transferase activity GO:0051338 355 0.045
regulation of purine nucleotide metabolic process GO:1900542 264 0.045
alcohol metabolic process GO:0006066 114 0.045
negative regulation of phosphate metabolic process GO:0045936 267 0.044
regulation of locomotion GO:0040012 329 0.044
regulation of mapk cascade GO:0043408 262 0.044
nucleoside phosphate catabolic process GO:1901292 412 0.044
purine ribonucleoside metabolic process GO:0046128 437 0.044
regulation of purine nucleotide catabolic process GO:0033121 205 0.044
lipid metabolic process GO:0006629 381 0.042
nephron tubule formation GO:0072079 1 0.041
actin cytoskeleton organization GO:0030036 207 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
response to cytokine GO:0034097 232 0.040
signal transduction by phosphorylation GO:0023014 297 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.037
nucleotide biosynthetic process GO:0009165 109 0.037
purine nucleoside catabolic process GO:0006152 398 0.036
oxidation reduction process GO:0055114 396 0.036
positive regulation of nucleotide catabolic process GO:0030813 185 0.036
regulation of nucleotide catabolic process GO:0030811 205 0.035
mapk cascade GO:0000165 288 0.034
purine nucleoside monophosphate metabolic process GO:0009126 186 0.034
peptidyl tyrosine modification GO:0018212 170 0.034
negative regulation of cell proliferation GO:0008285 228 0.034
ureteric bud formation GO:0060676 1 0.034
organic hydroxy compound metabolic process GO:1901615 147 0.033
leukocyte activation GO:0045321 164 0.033
anion transport GO:0006820 161 0.033
cell morphogenesis GO:0000902 296 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
purine nucleotide biosynthetic process GO:0006164 84 0.033
nucleoside catabolic process GO:0009164 408 0.033
glycerolipid metabolic process GO:0046486 107 0.032
positive regulation of nucleotide metabolic process GO:0045981 230 0.032
vesicle mediated transport GO:0016192 371 0.032
innate immune response GO:0045087 178 0.032
chemotaxis GO:0006935 157 0.031
positive regulation of cell death GO:0010942 263 0.031
taxis GO:0042330 157 0.031
purine ribonucleotide biosynthetic process GO:0009152 79 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.030
positive regulation of apoptotic process GO:0043065 246 0.030
purine containing compound biosynthetic process GO:0072522 88 0.029
nitrogen compound transport GO:0071705 191 0.029
post embryonic development GO:0009791 2 0.029
immune response GO:0006955 307 0.028
response to endoplasmic reticulum stress GO:0034976 49 0.028
regulation of actin filament based process GO:0032970 141 0.028
regulation of axon guidance GO:1902667 3 0.028
viral life cycle GO:0019058 132 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
lipid biosynthetic process GO:0008610 177 0.028
epithelial cell differentiation GO:0030855 141 0.028
establishment of planar polarity GO:0001736 3 0.028
regulation of growth GO:0040008 165 0.028
membrane organization GO:0061024 292 0.028
nucleotide catabolic process GO:0009166 408 0.027
rho protein signal transduction GO:0007266 26 0.027
actin mediated cell contraction GO:0070252 12 0.027
protein catabolic process GO:0030163 325 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.026
guanosine containing compound metabolic process GO:1901068 244 0.026
positive regulation of catabolic process GO:0009896 310 0.026
nucleoside monophosphate metabolic process GO:0009123 191 0.026
morphogenesis of an epithelium GO:0002009 60 0.026
cellular component morphogenesis GO:0032989 314 0.025
transmembrane transport GO:0055085 399 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
spermatid development GO:0007286 4 0.025
gtp catabolic process GO:0006184 237 0.025
organophosphate ester transport GO:0015748 32 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.024
rna processing GO:0006396 255 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
response to oxidative stress GO:0006979 121 0.024
regulation of actin cytoskeleton organization GO:0032956 116 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
atp catabolic process GO:0006200 157 0.024
peptidyl tyrosine phosphorylation GO:0018108 170 0.024
determination of adult lifespan GO:0008340 2 0.024
plasma membrane organization GO:0007009 115 0.024
immune response activating signal transduction GO:0002757 90 0.024
regulation of cell development GO:0060284 161 0.024
neuron development GO:0048666 113 0.024
small gtpase mediated signal transduction GO:0007264 78 0.023
translation GO:0006412 132 0.023
neurotransmitter secretion GO:0007269 4 0.023
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
lipid transport GO:0006869 90 0.023
morphogenesis of a polarized epithelium GO:0001738 3 0.023
regulation of cell adhesion GO:0030155 166 0.023
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.023
regulation of stress activated mapk cascade GO:0032872 84 0.023
cell morphogenesis involved in differentiation GO:0000904 144 0.023
multicellular organismal aging GO:0010259 3 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
phospholipid metabolic process GO:0006644 99 0.022
interspecies interaction between organisms GO:0044419 156 0.022
regulation of cell morphogenesis GO:0022604 153 0.022
regulation of kinase activity GO:0043549 314 0.022
inorganic cation transmembrane transport GO:0098662 194 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
regulation of cell motility GO:2000145 299 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
purine containing compound catabolic process GO:0072523 411 0.021
single organismal cell cell adhesion GO:0016337 148 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
epithelium development GO:0060429 227 0.021
primary neural tube formation GO:0014020 3 0.021
regulation of cell migration GO:0030334 289 0.021
regulation of cell projection organization GO:0031344 107 0.021
regulation of cell differentiation GO:0045595 393 0.021
oocyte development GO:0048599 1 0.021
locomotory behavior GO:0007626 1 0.020
peptidyl serine phosphorylation GO:0018105 101 0.020
regulation of chemotaxis GO:0050920 74 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.020
actin filament capping GO:0051693 4 0.020
regulation of defense response GO:0031347 154 0.020
neurogenesis GO:0022008 169 0.020
regulation of cytokine production GO:0001817 232 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
nucleoside diphosphate metabolic process GO:0009132 16 0.020
neuron differentiation GO:0030182 138 0.020
purine ribonucleoside biosynthetic process GO:0046129 23 0.020
regulation of response to external stimulus GO:0032101 222 0.020
apoptotic signaling pathway GO:0097190 268 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
epidermis development GO:0008544 59 0.020
positive regulation of gtp catabolic process GO:0033126 166 0.019
positive regulation of immune response GO:0050778 159 0.019
regulation of phagocytosis engulfment GO:0060099 2 0.019
lymphocyte activation GO:0046649 133 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.019
lipoprotein metabolic process GO:0042157 42 0.019
negative regulation of cell death GO:0060548 345 0.019
establishment of tissue polarity GO:0007164 3 0.019
alcohol biosynthetic process GO:0046165 52 0.019
glycolipid metabolic process GO:0006664 27 0.019
organic hydroxy compound biosynthetic process GO:1901617 71 0.019
cellular response to biotic stimulus GO:0071216 71 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
negative regulation of phosphorylation GO:0042326 174 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
regulation of proteolysis GO:0030162 293 0.018
regulation of jnk cascade GO:0046328 73 0.018
regulation of hormone levels GO:0010817 125 0.018
segmentation GO:0035282 4 0.018
chemical homeostasis GO:0048878 306 0.018
cell growth GO:0016049 160 0.018
protein o linked glycosylation GO:0006493 21 0.018
syncytium formation by plasma membrane fusion GO:0000768 2 0.018
regulation of protein complex assembly GO:0043254 147 0.018
barbed end actin filament capping GO:0051016 3 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
salivary gland morphogenesis GO:0007435 4 0.018
cell projection morphogenesis GO:0048858 129 0.018
glycoprotein biosynthetic process GO:0009101 91 0.018
regulation of cell activation GO:0050865 125 0.018
spermatid differentiation GO:0048515 4 0.017
response to molecule of bacterial origin GO:0002237 82 0.017
activation of immune response GO:0002253 114 0.017
response to tumor necrosis factor GO:0034612 76 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
negative regulation of transferase activity GO:0051348 124 0.017
regulation of mononuclear cell proliferation GO:0032944 65 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
neural tube closure GO:0001843 3 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
cellular response to molecule of bacterial origin GO:0071219 62 0.017
regulation of immune response GO:0050776 201 0.016
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.016
protein maturation GO:0051604 233 0.016
cellular response to lipid GO:0071396 127 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
cation transmembrane transport GO:0098655 238 0.016
heparin metabolic process GO:0030202 1 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
regulation of innate immune response GO:0045088 97 0.016
cell cycle phase transition GO:0044770 173 0.016
regulation of leukocyte activation GO:0002694 115 0.016
viral process GO:0016032 146 0.016
positive regulation of transport GO:0051050 336 0.016
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
ribonucleoside biosynthetic process GO:0042455 25 0.016
golgi ribbon formation GO:0090161 3 0.016
oocyte differentiation GO:0009994 2 0.016
positive regulation of phagocytosis engulfment GO:0060100 1 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
central nervous system development GO:0007417 123 0.015
nucleobase containing compound transport GO:0015931 51 0.015
negative regulation of nucleotide catabolic process GO:0030812 16 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
regulation of leukocyte migration GO:0002685 63 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
positive regulation of behavior GO:0048520 60 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
negative regulation of cytokine production GO:0001818 82 0.015
stress activated mapk cascade GO:0051403 93 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
cell part morphogenesis GO:0032990 137 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
regulation of intracellular transport GO:0032386 195 0.015
regulation of wnt signaling pathway GO:0030111 123 0.014
mrna metabolic process GO:0016071 175 0.014
actin filament organization GO:0007015 128 0.014
membrane lipid metabolic process GO:0006643 53 0.014
cell projection assembly GO:0030031 126 0.014
regulation of viral process GO:0050792 103 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
blood coagulation GO:0007596 76 0.014
wnt signaling pathway GO:0016055 156 0.014
positive regulation of leukocyte activation GO:0002696 80 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
glycerolipid biosynthetic process GO:0045017 51 0.014
endomembrane system organization GO:0010256 196 0.014
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.014
tube closure GO:0060606 3 0.014
glycoprotein metabolic process GO:0009100 110 0.014
rhythmic behavior GO:0007622 2 0.014
polysaccharide metabolic process GO:0005976 33 0.014
cytoplasmic transport GO:0016482 379 0.014
regulation of protein kinase activity GO:0045859 289 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
phosphatidylinositol metabolic process GO:0046488 53 0.014
single organism cellular localization GO:1902580 332 0.014
metal ion transport GO:0030001 272 0.013
tissue morphogenesis GO:0048729 96 0.013
multi organism cellular process GO:0044764 156 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
positive regulation of cytokine production GO:0001819 167 0.013
epidermal cell differentiation GO:0009913 45 0.013
membrane lipid biosynthetic process GO:0046467 27 0.013
regulation of cell cell adhesion GO:0022407 57 0.013
regulation of secretion GO:0051046 194 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
inner ear morphogenesis GO:0042472 4 0.013
neuron projection development GO:0031175 106 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.013
negative regulation of developmental process GO:0051093 247 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
associative learning GO:0008306 1 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
coagulation GO:0050817 78 0.013
chromatin modification GO:0016568 298 0.013
negative regulation of immune system process GO:0002683 136 0.012
system process GO:0003008 349 0.012
defense response GO:0006952 315 0.012
brain development GO:0007420 97 0.012
immune system development GO:0002520 195 0.012
regulation of nervous system development GO:0051960 88 0.012
response to oxygen containing compound GO:1901700 369 0.012
negative regulation of growth GO:0045926 97 0.012
nucleoside triphosphate biosynthetic process GO:0009142 20 0.012
head development GO:0060322 108 0.012
negative regulation of catabolic process GO:0009895 104 0.012
positive regulation of transferase activity GO:0051347 227 0.012
protein autophosphorylation GO:0046777 123 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.012
cellular carbohydrate biosynthetic process GO:0034637 21 0.012
positive regulation of cell adhesion GO:0045785 84 0.012
cell chemotaxis GO:0060326 112 0.012
mitochondrion organization GO:0007005 156 0.012
transforming growth factor beta production GO:0071604 14 0.012
protein glycosylation GO:0006486 62 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
negative regulation of protein modification process GO:0031400 200 0.012
monocyte activation GO:0042117 3 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
regulation of cell growth GO:0001558 135 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
positive regulation of innate immune response GO:0045089 79 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
regulation of actin filament length GO:0030832 56 0.012
glycerophospholipid biosynthetic process GO:0046474 40 0.012
response to fungus GO:0009620 4 0.012
regulation of cellular component size GO:0032535 82 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
neural tube formation GO:0001841 3 0.012
dicarboxylic acid metabolic process GO:0043648 29 0.012
cellular protein catabolic process GO:0044257 261 0.012
guanosine containing compound catabolic process GO:1901069 239 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
anterior posterior axis specification GO:0009948 2 0.011
mrna processing GO:0006397 133 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
protein localization to membrane GO:0072657 160 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
regulation of anatomical structure size GO:0090066 101 0.011
cellular response to lipopolysaccharide GO:0071222 57 0.011
dna repair GO:0006281 198 0.011
regulation of multi organism process GO:0043900 157 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
organic acid biosynthetic process GO:0016053 97 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
response to lipid GO:0033993 206 0.011
chromatin organization GO:0006325 351 0.011
nuclear transport GO:0051169 179 0.011
hemostasis GO:0007599 76 0.011
regulation of lymphocyte migration GO:2000401 22 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
tissue migration GO:0090130 119 0.011
immune effector process GO:0002252 159 0.011
negative regulation of filopodium assembly GO:0051490 0 0.011
regulation of peptidase activity GO:0052547 180 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
steroid metabolic process GO:0008202 94 0.010
positive regulation of keratinocyte migration GO:0051549 4 0.010
retina vasculature development in camera type eye GO:0061298 3 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
ossification GO:0001503 121 0.010
response to salt stress GO:0009651 3 0.010
positive regulation of growth GO:0045927 58 0.010
response to organic cyclic compound GO:0014070 204 0.010
neurological system process GO:0050877 163 0.010
circadian behavior GO:0048512 2 0.010
negative regulation of cell cycle GO:0045786 193 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.010
leukocyte migration GO:0050900 107 0.010
camp metabolic process GO:0046058 61 0.010
positive regulation of cell activation GO:0050867 81 0.010
protein localization to organelle GO:0033365 280 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
receptor transactivation GO:0035624 4 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
regulation of protein depolymerization GO:1901879 22 0.010
glycosylation GO:0070085 71 0.010
regulation of lipid transport GO:0032368 44 0.010

TMEM123 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.038
nervous system disease DOID:863 431 0.038
eye and adnexa disease DOID:1492 150 0.036
eye disease DOID:5614 149 0.036
disease of metabolism DOID:0014667 295 0.030
inherited metabolic disorder DOID:655 242 0.030
central nervous system disease DOID:331 186 0.029
disease of mental health DOID:150 70 0.026
neurodegenerative disease DOID:1289 102 0.024
retinal disease DOID:5679 118 0.022
retinal degeneration DOID:8466 89 0.022
musculoskeletal system disease DOID:17 223 0.017
muscular disease DOID:0080000 114 0.012
carbohydrate metabolic disorder DOID:2978 55 0.010