Homo sapiens

83 known processes

PDE1B

phosphodiesterase 1B, calmodulin-dependent

(Aliases: PDE1B1,PDES1B)

PDE1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 399 0.706
ion transmembrane transport GO:0034220 338 0.449
metal ion transport GO:0030001 272 0.323
cation transport GO:0006812 331 0.291
system process GO:0003008 349 0.271
ion homeostasis GO:0050801 230 0.263
cyclic nucleotide metabolic process GO:0009187 82 0.234
chemical homeostasis GO:0048878 306 0.219
cation transmembrane transport GO:0098655 238 0.204
cellular ion homeostasis GO:0006873 168 0.201
inorganic ion transmembrane transport GO:0098660 231 0.198
regulation of ion transport GO:0043269 189 0.198
metal ion homeostasis GO:0055065 169 0.157
regulation of ion transmembrane transport GO:0034765 132 0.149
regulation of transmembrane transport GO:0034762 139 0.147
neurological system process GO:0050877 163 0.143
cation homeostasis GO:0055080 189 0.141
cellular divalent inorganic cation homeostasis GO:0072503 128 0.137
divalent metal ion transport GO:0070838 152 0.134
regulation of cellular amine metabolic process GO:0033238 11 0.133
calcium ion transport GO:0006816 147 0.132
positive regulation of cellular amine metabolic process GO:0033240 7 0.128
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.128
cellular response to endogenous stimulus GO:0071495 336 0.128
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.126
cellular amine metabolic process GO:0044106 41 0.126
cellular chemical homeostasis GO:0055082 180 0.124
regulation of membrane potential GO:0042391 95 0.122
regulation of secretion by cell GO:1903530 177 0.121
divalent inorganic cation transport GO:0072511 158 0.118
cellular metal ion homeostasis GO:0006875 146 0.116
calcium ion homeostasis GO:0055074 122 0.115
regulation of cellular amino acid metabolic process GO:0006521 6 0.114
regulation of cellular ketone metabolic process GO:0010565 50 0.114
secretion by cell GO:0032940 226 0.105
cellular amino acid metabolic process GO:0006520 116 0.105
amine metabolic process GO:0009308 44 0.104
regulation of secretion GO:0051046 194 0.103
regulation of purine nucleotide metabolic process GO:1900542 264 0.103
cellular homeostasis GO:0019725 196 0.103
divalent inorganic cation homeostasis GO:0072507 136 0.103
positive regulation of phosphorylation GO:0042327 394 0.101
regulation of cellular component biogenesis GO:0044087 281 0.098
regulation of transmembrane transporter activity GO:0022898 74 0.095
muscle system process GO:0003012 81 0.095
cytosolic calcium ion homeostasis GO:0051480 89 0.094
secretion GO:0046903 254 0.091
potassium ion transport GO:0006813 62 0.091
regulation of calcium ion transport GO:0051924 79 0.089
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.089
positive regulation of transport GO:0051050 336 0.087
locomotory behavior GO:0007626 1 0.087
cellular calcium ion homeostasis GO:0006874 117 0.085
cellular ketone metabolic process GO:0042180 80 0.084
lipid metabolic process GO:0006629 381 0.081
ribonucleotide catabolic process GO:0009261 405 0.081
regulation of nucleotide biosynthetic process GO:0030808 50 0.080
positive regulation of nucleotide metabolic process GO:0045981 230 0.080
regulation of mapk cascade GO:0043408 262 0.080
regulation of nucleotide metabolic process GO:0006140 269 0.080
nucleoside phosphate biosynthetic process GO:1901293 109 0.078
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.078
inorganic cation transmembrane transport GO:0098662 194 0.077
regulation of cell differentiation GO:0045595 393 0.076
guanosine containing compound metabolic process GO:1901068 244 0.076
positive regulation of developmental process GO:0051094 314 0.074
positive regulation of hydrolase activity GO:0051345 331 0.074
negative regulation of multicellular organismal process GO:0051241 317 0.074
synaptic transmission GO:0007268 61 0.074
neuromuscular junction development GO:0007528 3 0.073
negative regulation of transport GO:0051051 176 0.072
cell cell signaling GO:0007267 155 0.072
cyclic purine nucleotide metabolic process GO:0052652 60 0.072
response to oxygen containing compound GO:1901700 369 0.072
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.070
cellular response to oxygen containing compound GO:1901701 276 0.070
Human
associative learning GO:0008306 1 0.069
regulation of metal ion transport GO:0010959 120 0.069
ribonucleoside triphosphate metabolic process GO:0009199 412 0.067
camp metabolic process GO:0046058 61 0.067
ribonucleotide biosynthetic process GO:0009260 81 0.066
positive regulation of cell proliferation GO:0008284 301 0.066
positive regulation of cellular component organization GO:0051130 376 0.066
nucleoside phosphate catabolic process GO:1901292 412 0.066
response to organonitrogen compound GO:0010243 156 0.065
Human
cellular cation homeostasis GO:0030003 163 0.065
memory GO:0007613 3 0.064
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.064
ras protein signal transduction GO:0007265 73 0.063
defense response GO:0006952 315 0.063
nervous system development GO:0007399 293 0.063
carbohydrate derivative biosynthetic process GO:1901137 207 0.062
response to nitrogen compound GO:1901698 184 0.061
Human
cyclic nucleotide biosynthetic process GO:0009190 61 0.061
purine nucleotide biosynthetic process GO:0006164 84 0.061
sensory perception GO:0007600 103 0.060
nucleotide biosynthetic process GO:0009165 109 0.059
vesicle mediated transport GO:0016192 371 0.059
regulation of synaptic plasticity GO:0048167 3 0.058
cellular lipid metabolic process GO:0044255 303 0.057
action potential GO:0001508 34 0.057
purine ribonucleotide biosynthetic process GO:0009152 79 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.054
enzyme linked receptor protein signaling pathway GO:0007167 303 0.054
post embryonic development GO:0009791 2 0.053
cytokine production GO:0001816 247 0.053
Human
cell development GO:0048468 328 0.053
muscle contraction GO:0006936 73 0.053
regulation of ion transmembrane transporter activity GO:0032412 72 0.052
organophosphate biosynthetic process GO:0090407 163 0.051
growth GO:0040007 202 0.051
immune response GO:0006955 307 0.051
Human
positive regulation of mapk cascade GO:0043410 190 0.051
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.051
positive regulation of cellular catabolic process GO:0031331 284 0.051
regulation of cytokine production GO:0001817 232 0.050
Human
purine ribonucleoside metabolic process GO:0046128 437 0.050
regulation of transporter activity GO:0032409 82 0.050
multicellular organismal signaling GO:0035637 34 0.050
cellular component morphogenesis GO:0032989 314 0.050
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.050
behavior GO:0007610 112 0.049
ribonucleoside catabolic process GO:0042454 406 0.048
positive regulation of catabolic process GO:0009896 310 0.048
blood circulation GO:0008015 113 0.048
positive regulation of protein phosphorylation GO:0001934 313 0.047
mapk cascade GO:0000165 288 0.047
gtp catabolic process GO:0006184 237 0.047
purine nucleoside catabolic process GO:0006152 398 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.046
biological adhesion GO:0022610 331 0.046
cellular response to organonitrogen compound GO:0071417 124 0.046
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.046
organophosphate catabolic process GO:0046434 430 0.046
signal transduction by phosphorylation GO:0023014 297 0.045
nucleoside triphosphate metabolic process GO:0009141 422 0.045
membrane organization GO:0061024 292 0.044
cellular response to nitrogen compound GO:1901699 144 0.044
Human
cgmp catabolic process GO:0046069 3 0.044
purine nucleoside triphosphate catabolic process GO:0009146 392 0.044
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
positive regulation of gtp catabolic process GO:0033126 166 0.043
positive regulation of transferase activity GO:0051347 227 0.043
regulation of transferase activity GO:0051338 355 0.042
actin filament based process GO:0030029 224 0.042
positive regulation of ion transport GO:0043270 87 0.042
response to abiotic stimulus GO:0009628 336 0.042
nucleoside catabolic process GO:0009164 408 0.042
organic anion transport GO:0015711 103 0.041
positive regulation of apoptotic process GO:0043065 246 0.041
regulation of cell cycle GO:0051726 393 0.040
single organism cellular localization GO:1902580 332 0.040
ribose phosphate biosynthetic process GO:0046390 82 0.040
guanosine containing compound catabolic process GO:1901069 239 0.040
positive regulation of protein kinase activity GO:0045860 190 0.040
cytoplasmic transport GO:0016482 379 0.039
purine nucleotide catabolic process GO:0006195 405 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.039
regulation of gtp catabolic process GO:0033124 180 0.039
purine ribonucleotide catabolic process GO:0009154 404 0.039
female gamete generation GO:0007292 2 0.039
regulation of protein kinase activity GO:0045859 289 0.039
purine containing compound catabolic process GO:0072523 411 0.039
purine containing compound biosynthetic process GO:0072522 88 0.038
positive regulation of gtpase activity GO:0043547 166 0.038
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
nucleotide catabolic process GO:0009166 408 0.038
circadian behavior GO:0048512 2 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
cell morphogenesis GO:0000902 296 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
response to organic cyclic compound GO:0014070 204 0.037
Human
regulation of system process GO:0044057 101 0.037
negative regulation of cellular component organization GO:0051129 235 0.037
oogenesis GO:0048477 2 0.036
single organism membrane organization GO:0044802 268 0.036
regulation of small gtpase mediated signal transduction GO:0051056 156 0.036
regulation of protein localization GO:0032880 296 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
multicellular organismal aging GO:0010259 3 0.035
glycosyl compound catabolic process GO:1901658 413 0.035
potassium ion transmembrane transport GO:0071805 60 0.035
small gtpase mediated signal transduction GO:0007264 78 0.035
cell adhesion GO:0007155 325 0.035
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.035
sleep GO:0030431 2 0.035
response to cytokine GO:0034097 232 0.035
cell projection organization GO:0030030 252 0.035
negative regulation of secretion by cell GO:1903531 52 0.035
cardiac muscle cell contraction GO:0086003 4 0.035
response to biotic stimulus GO:0009607 276 0.035
regulation of locomotion GO:0040012 329 0.035
regulation of kinase activity GO:0043549 314 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
second messenger mediated signaling GO:0019932 78 0.034
gtp metabolic process GO:0046039 239 0.034
postsynaptic membrane organization GO:0001941 2 0.034
rhythmic behavior GO:0007622 2 0.034
regulation of cellular component movement GO:0051270 334 0.034
regulation of cell cycle process GO:0010564 266 0.034
cellular macromolecule catabolic process GO:0044265 380 0.034
circulatory system process GO:0003013 113 0.034
mitotic cell cycle process GO:1903047 286 0.033
cellular response to cytokine stimulus GO:0071345 181 0.033
regulation of protein transport GO:0051223 213 0.033
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.033
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.033
negative regulation of cell death GO:0060548 345 0.033
activation of protein kinase activity GO:0032147 90 0.033
protein oligomerization GO:0051259 173 0.033
cellular response to organic cyclic compound GO:0071407 127 0.032
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.032
regulation of response to external stimulus GO:0032101 222 0.032
regulation of gtpase activity GO:0043087 180 0.032
cell activation GO:0001775 213 0.032
monovalent inorganic cation transport GO:0015672 128 0.032
neurotransmitter secretion GO:0007269 4 0.032
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.032
neurogenesis GO:0022008 169 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
hematopoietic or lymphoid organ development GO:0048534 186 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
camp biosynthetic process GO:0006171 47 0.031
mitotic cell cycle GO:0000278 326 0.031
positive regulation of programmed cell death GO:0043068 249 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.030
generation of neurons GO:0048699 152 0.030
regulation of nucleoside metabolic process GO:0009118 209 0.030
cellular potassium ion transport GO:0071804 60 0.030
determination of adult lifespan GO:0008340 2 0.030
positive regulation of cell death GO:0010942 263 0.030
response to hormone GO:0009725 175 0.030
anion transport GO:0006820 161 0.030
sequestering of metal ion GO:0051238 24 0.029
positive regulation of cytokine production GO:0001819 167 0.029
Human
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.029
cellular macromolecular complex assembly GO:0034622 324 0.029
regulation of proteolysis GO:0030162 293 0.029
positive regulation of kinase activity GO:0033674 204 0.028
lipid biosynthetic process GO:0008610 177 0.028
peptidyl tyrosine modification GO:0018212 170 0.028
regulation of cell motility GO:2000145 299 0.028
actin cytoskeleton organization GO:0030036 207 0.028
positive regulation of synaptic transmission GO:0050806 4 0.027
response to external biotic stimulus GO:0043207 261 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
positive regulation of cell differentiation GO:0045597 211 0.027
protein catabolic process GO:0030163 325 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.027
reactive nitrogen species metabolic process GO:2001057 3 0.027
positive regulation of organelle organization GO:0010638 195 0.027
chromatin organization GO:0006325 351 0.026
dephosphorylation GO:0016311 209 0.026
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.026
positive regulation of immune response GO:0050778 159 0.026
Human
innate immune response GO:0045087 178 0.026
negative regulation of secretion GO:0051048 58 0.026
response to growth factor GO:0070848 205 0.026
protein processing GO:0016485 226 0.026
carbohydrate metabolic process GO:0005975 207 0.026
reactive oxygen species biosynthetic process GO:1903409 4 0.026
regulation of protein complex assembly GO:0043254 147 0.026
immune system development GO:0002520 195 0.026
regulation of camp metabolic process GO:0030814 52 0.025
cardiovascular system development GO:0072358 262 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
covalent chromatin modification GO:0016569 254 0.025
regulation of response to wounding GO:1903034 101 0.025
striated muscle contraction GO:0006941 52 0.025
immune effector process GO:0002252 159 0.025
adult locomotory behavior GO:0008344 1 0.025
regulation of cell development GO:0060284 161 0.025
response to virus GO:0009615 126 0.025
chromatin modification GO:0016568 298 0.025
regulation of hormone levels GO:0010817 125 0.024
regulation of cell activation GO:0050865 125 0.024
lipid localization GO:0010876 106 0.024
regulation of cell migration GO:0030334 289 0.024
rho protein signal transduction GO:0007266 26 0.024
regulation of protein secretion GO:0050708 86 0.024
positive regulation of immune system process GO:0002684 283 0.024
Human
leukocyte activation GO:0045321 164 0.024
protein maturation GO:0051604 233 0.024
epithelial cell proliferation GO:0050673 128 0.024
response to lipid GO:0033993 206 0.024
regulation of neurotransmitter secretion GO:0046928 3 0.024
positive regulation of camp biosynthetic process GO:0030819 35 0.024
regulation of camp biosynthetic process GO:0030817 45 0.023
sensory perception of pain GO:0019233 4 0.023
regulation of acrosome reaction GO:0060046 4 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.023
reactive oxygen species metabolic process GO:0072593 75 0.023
negative regulation of developmental process GO:0051093 247 0.023
protein ubiquitination GO:0016567 314 0.023
response to other organism GO:0051707 261 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
regeneration GO:0031099 4 0.023
central nervous system development GO:0007417 123 0.022
multicellular organismal response to stress GO:0033555 1 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
blastoderm segmentation GO:0007350 2 0.022
regulation of immune response GO:0050776 201 0.022
Human
calcium ion transmembrane transport GO:0070588 76 0.022
glycerolipid metabolic process GO:0046486 107 0.022
nitrogen compound transport GO:0071705 191 0.022
cell growth GO:0016049 160 0.022
maintenance of location GO:0051235 112 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
protein localization to organelle GO:0033365 280 0.022
sodium ion transmembrane transport GO:0035725 59 0.022
wound healing GO:0042060 115 0.022
lipid transport GO:0006869 90 0.021
segmentation GO:0035282 4 0.021
glycoprotein metabolic process GO:0009100 110 0.021
regulation of actin filament based process GO:0032970 141 0.021
oocyte differentiation GO:0009994 2 0.021
histone modification GO:0016570 251 0.021
regulation of intracellular transport GO:0032386 195 0.021
regulation of growth GO:0040008 165 0.021
signal release GO:0023061 70 0.021
negative regulation of lipid metabolic process GO:0045833 38 0.021
negative regulation of ion transport GO:0043271 39 0.021
exocytosis GO:0006887 71 0.020
sequestering of calcium ion GO:0051208 17 0.020
cardiac muscle contraction GO:0060048 34 0.020
small molecule biosynthetic process GO:0044283 157 0.020
positive regulation of cellular component biogenesis GO:0044089 158 0.020
regulation of ras gtpase activity GO:0032318 128 0.020
regulation of actin cytoskeleton organization GO:0032956 116 0.020
neuron differentiation GO:0030182 138 0.020
regulation of cytoplasmic transport GO:1903649 149 0.020
immune response activating signal transduction GO:0002757 90 0.020
Human
response to radiation GO:0009314 151 0.020
response to wounding GO:0009611 168 0.020
visual learning GO:0008542 1 0.020
angiogenesis GO:0001525 147 0.020
protein secretion GO:0009306 98 0.019
intracellular protein transport GO:0006886 270 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.019
apoptotic signaling pathway GO:0097190 268 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.019
cellular protein catabolic process GO:0044257 261 0.019
response to metal ion GO:0010038 84 0.019
negative regulation of cell migration GO:0030336 102 0.019
interspecies interaction between organisms GO:0044419 156 0.019
neuron development GO:0048666 113 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
lipid catabolic process GO:0016042 84 0.019
regulation of map kinase activity GO:0043405 108 0.019
positive regulation of camp metabolic process GO:0030816 41 0.019
cellular response to hormone stimulus GO:0032870 125 0.019
oocyte development GO:0048599 1 0.019
oxidation reduction process GO:0055114 396 0.019
protein localization to membrane GO:0072657 160 0.019
regulation of protein catabolic process GO:0042176 155 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
regulation of neuronal synaptic plasticity GO:0048168 1 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
negative regulation of protein modification process GO:0031400 200 0.018
organic hydroxy compound transport GO:0015850 63 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
long term memory GO:0007616 2 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
cell projection morphogenesis GO:0048858 129 0.018
circulatory system development GO:0072359 262 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
ameboidal type cell migration GO:0001667 135 0.018
multi organism cellular process GO:0044764 156 0.018
negative regulation of immune system process GO:0002683 136 0.018
synaptic transmission involved in micturition GO:0060084 2 0.018
visual behavior GO:0007632 2 0.018
cellular protein complex assembly GO:0043623 188 0.018
protein targeting GO:0006605 187 0.018
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.018
limbic system development GO:0021761 3 0.018
regulation of peptidase activity GO:0052547 180 0.018
cell part morphogenesis GO:0032990 137 0.018
endomembrane system organization GO:0010256 196 0.018
negative regulation of cell cycle GO:0045786 193 0.018
endocytosis GO:0006897 159 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
regulation of defense response GO:0031347 154 0.017
negative regulation of cellular component movement GO:0051271 106 0.017
cell type specific apoptotic process GO:0097285 125 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
regulation of blood circulation GO:1903522 59 0.017
regulation of endothelial cell proliferation GO:0001936 56 0.017
positive regulation of proteolysis GO:0045862 142 0.017
immune response regulating signaling pathway GO:0002764 97 0.017
Human
heart process GO:0003015 62 0.017
cyclic nucleotide mediated signaling GO:0019935 26 0.017
regulation of protein serine threonine kinase activity GO:0071900 179 0.017
blood vessel morphogenesis GO:0048514 162 0.017
cell division GO:0051301 168 0.017
transmission of nerve impulse GO:0019226 11 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
erk1 and erk2 cascade GO:0070371 104 0.016
regulation of postsynaptic membrane potential GO:0060078 1 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.016
phospholipid metabolic process GO:0006644 99 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.016
actin filament organization GO:0007015 128 0.016
cell cycle phase transition GO:0044770 173 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
negative regulation of catabolic process GO:0009895 104 0.016
negative regulation of kinase activity GO:0033673 106 0.016
negative regulation of synaptic transmission GO:0050805 2 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
organ formation GO:0048645 3 0.016
single organism cell adhesion GO:0098602 179 0.016
receptor metabolic process GO:0043112 81 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
response to sucrose GO:0009744 1 0.016
response to oxidative stress GO:0006979 121 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 0.016
sensory perception of chemical stimulus GO:0007606 38 0.016
regulation of cellular response to stress GO:0080135 244 0.016
motor neuron axon guidance GO:0008045 2 0.015
actin filament based movement GO:0030048 17 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
response to axon injury GO:0048678 1 0.015
peripheral nervous system development GO:0007422 2 0.015
amide transport GO:0042886 76 0.015
regulation of axon extension involved in axon guidance GO:0048841 2 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
actin mediated cell contraction GO:0070252 12 0.015
developmental growth GO:0048589 48 0.015
phospholipase c activating adrenergic receptor signaling pathway GO:0071882 1 0.015
regulation of multi organism process GO:0043900 157 0.015
mitochondrion organization GO:0007005 156 0.015
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.015
calcium ion transport into cytosol GO:0060402 48 0.015
mating GO:0007618 1 0.015
organelle assembly GO:0070925 176 0.015
regulation of ion homeostasis GO:2000021 73 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of leukocyte activation GO:0002694 115 0.015
regulation of cell adhesion GO:0030155 166 0.015
response to disaccharide GO:0034285 1 0.015
epithelium migration GO:0090132 119 0.015
regulation of cell morphogenesis GO:0022604 153 0.014
positive regulation of locomotion GO:0040017 186 0.014
negative regulation of locomotion GO:0040013 118 0.014
negative regulation of cytokine production GO:0001818 82 0.014
lymphocyte activation GO:0046649 133 0.014
viral process GO:0016032 146 0.014
heart contraction GO:0060047 62 0.014
stem cell division GO:0017145 2 0.014
positive regulation of axon extension GO:0045773 4 0.014
regulation of immune effector process GO:0002697 91 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
circadian sleep wake cycle process GO:0022410 2 0.014
endothelial cell proliferation GO:0001935 65 0.014
negative regulation of transferase activity GO:0051348 124 0.014
spermatid development GO:0007286 4 0.014
sodium ion transport GO:0006814 61 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
calcium mediated signaling GO:0019722 44 0.014
cytosolic calcium ion transport GO:0060401 48 0.014
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.014
Human
regulation of body fluid levels GO:0050878 99 0.014
protein import GO:0017038 130 0.014
regulation of angiogenesis GO:0045765 92 0.014
positive regulation of calcium ion transport GO:0051928 51 0.014
anion transmembrane transport GO:0098656 76 0.014

PDE1B disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.042
central nervous system disease DOID:331 186 0.033
Human
nervous system disease DOID:863 431 0.033
Human
immune system disease DOID:2914 155 0.025
disease of cellular proliferation DOID:14566 174 0.019
sensory system disease DOID:0050155 203 0.019
eye and adnexa disease DOID:1492 150 0.018
cancer DOID:162 167 0.018
neurodegenerative disease DOID:1289 102 0.017
Human
organ system cancer DOID:0050686 164 0.016
inherited metabolic disorder DOID:655 242 0.016
musculoskeletal system disease DOID:17 223 0.015
Human