Homo sapiens

15 known processes

ARSA

arylsulfatase A

(Aliases: MLD)

ARSA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 381 0.101
cellular amino acid metabolic process GO:0006520 116 0.091
cellular lipid metabolic process GO:0044255 303 0.074
amine metabolic process GO:0009308 44 0.073
cellular amine metabolic process GO:0044106 41 0.068
cellular ketone metabolic process GO:0042180 80 0.065
system process GO:0003008 349 0.062
determination of adult lifespan GO:0008340 2 0.054
cellular homeostasis GO:0019725 196 0.051
regulation of cellular amino acid metabolic process GO:0006521 6 0.051
multicellular organismal aging GO:0010259 3 0.050
single organism carbohydrate metabolic process GO:0044723 193 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.045
neurological system process GO:0050877 163 0.042
protein processing GO:0016485 226 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
sulfur compound metabolic process GO:0006790 101 0.040
Human
positive regulation of hydrolase activity GO:0051345 331 0.039
organic anion transport GO:0015711 103 0.037
purine nucleotide catabolic process GO:0006195 405 0.037
carbohydrate metabolic process GO:0005975 207 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.036
defense response GO:0006952 315 0.036
cellular chemical homeostasis GO:0055082 180 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
post embryonic development GO:0009791 2 0.034
positive regulation of transport GO:0051050 336 0.034
locomotory behavior GO:0007626 1 0.034
oxidation reduction process GO:0055114 396 0.034
ion homeostasis GO:0050801 230 0.033
organonitrogen compound biosynthetic process GO:1901566 200 0.033
membrane organization GO:0061024 292 0.033
cation transport GO:0006812 331 0.032
lipid biosynthetic process GO:0008610 177 0.032
carboxylic acid transport GO:0046942 63 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.031
glycosyl compound catabolic process GO:1901658 413 0.031
anion transport GO:0006820 161 0.031
transmembrane transport GO:0055085 399 0.030
cellular cation homeostasis GO:0030003 163 0.029
ribonucleoside catabolic process GO:0042454 406 0.029
protein catabolic process GO:0030163 325 0.029
chemical homeostasis GO:0048878 306 0.028
cytoplasmic transport GO:0016482 379 0.028
lipid catabolic process GO:0016042 84 0.028
protein maturation GO:0051604 233 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
purine containing compound catabolic process GO:0072523 411 0.027
response to biotic stimulus GO:0009607 276 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
response to external biotic stimulus GO:0043207 261 0.026
immune response GO:0006955 307 0.026
small gtpase mediated signal transduction GO:0007264 78 0.025
cytokine production GO:0001816 247 0.025
alcohol metabolic process GO:0006066 114 0.025
organophosphate catabolic process GO:0046434 430 0.025
carboxylic acid catabolic process GO:0046395 71 0.025
female gamete generation GO:0007292 2 0.025
monocarboxylic acid metabolic process GO:0032787 185 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.024
neuromuscular junction development GO:0007528 3 0.024
organic acid transport GO:0015849 65 0.023
cell projection organization GO:0030030 252 0.023
cellular ion homeostasis GO:0006873 168 0.023
single organism membrane organization GO:0044802 268 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
protein localization to organelle GO:0033365 280 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
cellular protein catabolic process GO:0044257 261 0.022
nucleoside catabolic process GO:0009164 408 0.022
cellular amide metabolic process GO:0043603 69 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
nucleotide catabolic process GO:0009166 408 0.022
regulation of cellular response to stress GO:0080135 244 0.022
vacuole organization GO:0007033 44 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
regulation of gtp catabolic process GO:0033124 180 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
response to other organism GO:0051707 261 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
regulation of cytokine production GO:0001817 232 0.021
cellular macromolecule catabolic process GO:0044265 380 0.020
oogenesis GO:0048477 2 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
cell development GO:0048468 328 0.020
nervous system development GO:0007399 293 0.020
Rat
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
small molecule catabolic process GO:0044282 92 0.020
metal ion transport GO:0030001 272 0.020
phospholipid metabolic process GO:0006644 99 0.020
glycerolipid metabolic process GO:0046486 107 0.019
cellular component morphogenesis GO:0032989 314 0.019
regulation of kinase activity GO:0043549 314 0.019
vesicle mediated transport GO:0016192 371 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
cation homeostasis GO:0055080 189 0.019
cellular lipid catabolic process GO:0044242 65 0.019
nucleoside triphosphate catabolic process GO:0009143 394 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
regulation of transferase activity GO:0051338 355 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.018
regeneration GO:0031099 4 0.018
small molecule biosynthetic process GO:0044283 157 0.018
positive regulation of kinase activity GO:0033674 204 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
gtp metabolic process GO:0046039 239 0.018
secretion by cell GO:0032940 226 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
cellular modified amino acid metabolic process GO:0006575 64 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of protein localization GO:0032880 296 0.018
rhythmic behavior GO:0007622 2 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
regulation of response to external stimulus GO:0032101 222 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
response to oxygen containing compound GO:1901700 369 0.017
Rat
negative regulation of intracellular signal transduction GO:1902532 183 0.017
response to abiotic stimulus GO:0009628 336 0.017
Rat
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
regulation of protein kinase activity GO:0045859 289 0.017
cell morphogenesis GO:0000902 296 0.017
nitrogen compound transport GO:0071705 191 0.017
lipid transport GO:0006869 90 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
positive regulation of transferase activity GO:0051347 227 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
mitotic cell cycle process GO:1903047 286 0.017
negative regulation of cell death GO:0060548 345 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
amino acid transport GO:0006865 28 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
ras protein signal transduction GO:0007265 73 0.016
segmentation GO:0035282 4 0.016
carboxylic acid biosynthetic process GO:0046394 97 0.016
memory GO:0007613 3 0.016
organelle assembly GO:0070925 176 0.016
cell growth GO:0016049 160 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
regulation of protein transport GO:0051223 213 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
cell adhesion GO:0007155 325 0.016
maintenance of location GO:0051235 112 0.015
regulation of secretion GO:0051046 194 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
negative regulation of organelle organization GO:0010639 126 0.015
ion transmembrane transport GO:0034220 338 0.015
rho protein signal transduction GO:0007266 26 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
anatomical structure homeostasis GO:0060249 100 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
cellular carbohydrate metabolic process GO:0044262 84 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
positive regulation of locomotion GO:0040017 186 0.015
oocyte differentiation GO:0009994 2 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
intracellular protein transport GO:0006886 270 0.015
regulation of proteolysis GO:0030162 293 0.015
chromatin organization GO:0006325 351 0.015
blastoderm segmentation GO:0007350 2 0.015
glycoprotein metabolic process GO:0009100 110 0.015
peptide metabolic process GO:0006518 51 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
circadian behavior GO:0048512 2 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.014
positive regulation of cytokine production GO:0001819 167 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
biological adhesion GO:0022610 331 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
gtp catabolic process GO:0006184 237 0.014
response to wounding GO:0009611 168 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
mitochondrion organization GO:0007005 156 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
cellular protein complex assembly GO:0043623 188 0.014
regulation of protein catabolic process GO:0042176 155 0.014
actin filament based process GO:0030029 224 0.014
regulation of protein maturation GO:1903317 150 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
negative regulation of protein maturation GO:1903318 142 0.014
dephosphorylation GO:0016311 209 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
organic acid catabolic process GO:0016054 71 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
regulation of cell cycle GO:0051726 393 0.013
metal ion homeostasis GO:0055065 169 0.013
atp metabolic process GO:0046034 176 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
positive regulation of secretion GO:0051047 116 0.013
cell substrate adhesion GO:0031589 132 0.013
positive regulation of catabolic process GO:0009896 310 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
spermatid differentiation GO:0048515 4 0.013
organic acid biosynthetic process GO:0016053 97 0.013
regulation of cell cycle process GO:0010564 266 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
divalent inorganic cation homeostasis GO:0072507 136 0.013
single organism cellular localization GO:1902580 332 0.013
regulation of immune effector process GO:0002697 91 0.013
apoptotic signaling pathway GO:0097190 268 0.013
rab protein signal transduction GO:0032482 4 0.013
divalent inorganic cation transport GO:0072511 158 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
protein ubiquitination GO:0016567 314 0.013
cytokine mediated signaling pathway GO:0019221 109 0.013
generation of precursor metabolites and energy GO:0006091 68 0.013
oocyte development GO:0048599 1 0.013
positive regulation of rab gtpase activity GO:0032851 39 0.013
microtubule based process GO:0007017 210 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
divalent metal ion transport GO:0070838 152 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
peripheral nervous system development GO:0007422 2 0.012
membrane lipid metabolic process GO:0006643 53 0.012
regulation of secretion by cell GO:1903530 177 0.012
positive regulation of cell death GO:0010942 263 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
lipid localization GO:0010876 106 0.012
epithelium development GO:0060429 227 0.012
mitotic cell cycle GO:0000278 326 0.012
response to cytokine GO:0034097 232 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
negative regulation of immune system process GO:0002683 136 0.012
regulation of dna metabolic process GO:0051052 153 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
endomembrane system organization GO:0010256 196 0.012
cdc42 protein signal transduction GO:0032488 4 0.012
neurogenesis GO:0022008 169 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
regulation of immune response GO:0050776 201 0.012
response to bacterium GO:0009617 144 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of protein processing GO:0070613 150 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
response to axon injury GO:0048678 1 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
positive regulation of organelle organization GO:0010638 195 0.012
glycerolipid biosynthetic process GO:0045017 51 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
innate immune response GO:0045087 178 0.012
histone modification GO:0016570 251 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.011
response to fungus GO:0009620 4 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
negative regulation of response to external stimulus GO:0032102 83 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
chromatin modification GO:0016568 298 0.011
regulation of intracellular transport GO:0032386 195 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
protein localization to membrane GO:0072657 160 0.011
response to organic cyclic compound GO:0014070 204 0.011
Rat
modification dependent protein catabolic process GO:0019941 209 0.011
long term memory GO:0007616 2 0.011
mapk cascade GO:0000165 288 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
macromolecule glycosylation GO:0043413 63 0.011
anterior posterior axis specification GO:0009948 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
spermatid development GO:0007286 4 0.011
growth GO:0040007 202 0.011
endocytosis GO:0006897 159 0.011
compound eye development GO:0048749 1 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
nuclear transport GO:0051169 179 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
secretion GO:0046903 254 0.011
detection of stimulus involved in sensory perception GO:0050906 43 0.011
response to organonitrogen compound GO:0010243 156 0.011
peptidyl lysine modification GO:0018205 144 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
detection of chemical stimulus GO:0009593 55 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
blood circulation GO:0008015 113 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
cation transmembrane transport GO:0098655 238 0.011
protein autophosphorylation GO:0046777 123 0.011
regulation of defense response GO:0031347 154 0.011
muscle contraction GO:0006936 73 0.011
regulation of cell activation GO:0050865 125 0.011
regulation of dephosphorylation GO:0035303 96 0.010
cellular response to external stimulus GO:0071496 111 0.010
sensory perception GO:0007600 103 0.010
maintenance of location in cell GO:0051651 62 0.010
receptor metabolic process GO:0043112 81 0.010
regulation of mapk cascade GO:0043408 262 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
protein targeting GO:0006605 187 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
negative regulation of cell cycle GO:0045786 193 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
cell projection morphogenesis GO:0048858 129 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
metencephalon development GO:0022037 2 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
cell part morphogenesis GO:0032990 137 0.010
fatty acid metabolic process GO:0006631 115 0.010
sensory perception of smell GO:0007608 2 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
regulation of response to wounding GO:1903034 101 0.010
glutathione metabolic process GO:0006749 20 0.010
response to hormone GO:0009725 175 0.010
Rat
atp catabolic process GO:0006200 157 0.010
circulatory system process GO:0003013 113 0.010
calcium ion homeostasis GO:0055074 122 0.010

ARSA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.256
inherited metabolic disorder DOID:655 242 0.195
central nervous system disease DOID:331 186 0.056
nervous system disease DOID:863 431 0.056
neurodegenerative disease DOID:1289 102 0.030
carbohydrate metabolic disorder DOID:2978 55 0.021
glycogen storage disease DOID:2747 10 0.019
glycogen metabolism disorder DOID:0050728 10 0.019
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
musculoskeletal system disease DOID:17 223 0.015
connective tissue disease DOID:65 109 0.015
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
retinal disease DOID:5679 118 0.013
lysosomal storage disease DOID:3211 47 0.013
lipid storage disease DOID:9455 28 0.012
immune system disease DOID:2914 155 0.012
bone disease DOID:0080001 88 0.011
retinal degeneration DOID:8466 89 0.010
disease of mental health DOID:150 70 0.010
brain disease DOID:936 73 0.005
sphingolipidosis DOID:1927 14 0.004
cerebral degeneration DOID:1443 16 0.002
leukodystrophy DOID:10579 8 0.002