Homo sapiens

0 known processes

PLXND1

plexin D1

(Aliases: PLEXD1,KIAA0620,MGC75353)

PLXND1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
drinking behavior GO:0042756 1 0.997
negative regulation of alkaline phosphatase activity GO:0010693 2 0.941
regulation of locomotion GO:0040012 329 0.875
Human Mouse
positive regulation of collateral sprouting GO:0048672 2 0.777
regulation of axon guidance GO:1902667 3 0.773
collateral sprouting GO:0048668 2 0.763
regulation of cell motility GO:2000145 299 0.726
Human Mouse
ras protein signal transduction GO:0007265 73 0.672
glycosyl compound catabolic process GO:1901658 413 0.645
Human
semaphorin plexin signaling pathway GO:0071526 4 0.625
Human Mouse
regulation of cellular component movement GO:0051270 334 0.618
Human Mouse
nucleoside catabolic process GO:0009164 408 0.590
Human
regulation of axon extension involved in axon guidance GO:0048841 2 0.584
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.578
Human
guanosine containing compound metabolic process GO:1901068 244 0.537
Human
biological adhesion GO:0022610 331 0.522
Human
nucleoside phosphate catabolic process GO:1901292 412 0.521
Human
locomotory behavior GO:0007626 1 0.510
purine nucleoside catabolic process GO:0006152 398 0.504
Human
rho protein signal transduction GO:0007266 26 0.496
regulation of nucleotide catabolic process GO:0030811 205 0.484
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.470
small gtpase mediated signal transduction GO:0007264 78 0.463
regulation of gtp catabolic process GO:0033124 180 0.453
Human
gtp metabolic process GO:0046039 239 0.450
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.434
Human
ribonucleoside catabolic process GO:0042454 406 0.425
Human
positive regulation of nucleotide catabolic process GO:0030813 185 0.424
regulation of cell migration GO:0030334 289 0.403
Human Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.389
negative chemotaxis GO:0050919 11 0.389
cardiovascular system development GO:0072358 262 0.388
Mouse
positive regulation of cellular component movement GO:0051272 181 0.379
circulatory system development GO:0072359 262 0.374
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.372
Human
regulation of nucleotide metabolic process GO:0006140 269 0.359
Human
ribonucleotide catabolic process GO:0009261 405 0.359
Human
cellular amine metabolic process GO:0044106 41 0.343
ribonucleoside triphosphate catabolic process GO:0009203 391 0.341
Human
organophosphate catabolic process GO:0046434 430 0.336
Human
purine containing compound catabolic process GO:0072523 411 0.314
Human
blood vessel morphogenesis GO:0048514 162 0.308
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.305
Human
blood vessel development GO:0001568 172 0.303
Mouse
cellular component morphogenesis GO:0032989 314 0.303
Human
purine ribonucleotide catabolic process GO:0009154 404 0.300
Human
regulation of cell differentiation GO:0045595 393 0.299
ossification GO:0001503 121 0.299
purine ribonucleoside metabolic process GO:0046128 437 0.299
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.294
nucleotide catabolic process GO:0009166 408 0.294
Human
adult locomotory behavior GO:0008344 1 0.293
signal transduction by phosphorylation GO:0023014 297 0.291
positive regulation of cell motility GO:2000147 177 0.281
positive regulation of gtpase activity GO:0043547 166 0.275
positive regulation of cell migration GO:0030335 172 0.273
visual behavior GO:0007632 2 0.272
regulation of nucleoside metabolic process GO:0009118 209 0.265
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.261
Mouse
positive regulation of gtp catabolic process GO:0033126 166 0.260
taxis GO:0042330 157 0.260
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.258
Human
positive regulation of protein phosphorylation GO:0001934 313 0.255
regulation of rho gtpase activity GO:0032319 66 0.244
bone development GO:0060348 26 0.241
epithelial cell migration GO:0010631 119 0.236
Mouse
positive regulation of cell development GO:0010720 92 0.231
cell morphogenesis GO:0000902 296 0.225
Human
positive regulation of developmental process GO:0051094 314 0.224
gtp catabolic process GO:0006184 237 0.222
Human
positive regulation of hydrolase activity GO:0051345 331 0.220
positive regulation of nucleotide metabolic process GO:0045981 230 0.218
purine ribonucleoside catabolic process GO:0046130 398 0.212
Human
positive regulation of ras gtpase activity GO:0032320 117 0.211
cell development GO:0048468 328 0.210
regulation of purine nucleotide catabolic process GO:0033121 205 0.205
Human
positive regulation of rho gtpase activity GO:0032321 56 0.204
negative regulation of cell adhesion GO:0007162 64 0.200
Human
negative regulation of multicellular organismal process GO:0051241 317 0.190
homotypic cell cell adhesion GO:0034109 47 0.185
negative regulation of phosphate metabolic process GO:0045936 267 0.184
Human
regulation of cell adhesion GO:0030155 166 0.182
Human
olfactory bulb development GO:0021772 5 0.182
positive regulation of cellular component organization GO:0051130 376 0.180
regulation of gtpase activity GO:0043087 180 0.178
Human
angiogenesis GO:0001525 147 0.178
Mouse
positive regulation of cell differentiation GO:0045597 211 0.177
mapk cascade GO:0000165 288 0.176
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.173
cell morphogenesis involved in differentiation GO:0000904 144 0.172
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.171
regulation of rho protein signal transduction GO:0035023 79 0.169
negative regulation of hydrolase activity GO:0051346 182 0.168
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.166
Human
regulation of ras protein signal transduction GO:0046578 155 0.166
positive regulation of locomotion GO:0040017 186 0.165
leukocyte cell cell adhesion GO:0007159 37 0.163
regulation of small gtpase mediated signal transduction GO:0051056 156 0.161
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.161
negative regulation of phosphorus metabolic process GO:0010563 267 0.159
Human
vasculature development GO:0001944 181 0.156
Mouse
negative regulation of catalytic activity GO:0043086 335 0.155
Human
positive regulation of cell growth GO:0030307 48 0.152
ribonucleoside triphosphate metabolic process GO:0009199 412 0.151
Human
positive regulation of mapk cascade GO:0043410 190 0.148
positive regulation of catabolic process GO:0009896 310 0.146
single organismal cell cell adhesion GO:0016337 148 0.142
positive regulation of cellular catabolic process GO:0031331 284 0.140
regulation of anatomical structure morphogenesis GO:0022603 286 0.139
Human Mouse
regulation of epithelial cell migration GO:0010632 93 0.139
positive regulation of phosphorylation GO:0042327 394 0.139
purine nucleotide catabolic process GO:0006195 405 0.132
Human
response to abiotic stimulus GO:0009628 336 0.129
regulation of growth GO:0040008 165 0.128
nucleoside triphosphate metabolic process GO:0009141 422 0.126
Human
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.125
dephosphorylation GO:0016311 209 0.124
nervous system development GO:0007399 293 0.122
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.117
cell projection organization GO:0030030 252 0.117
negative regulation of phosphatase activity GO:0010923 61 0.113
response to radiation GO:0009314 151 0.111
central nervous system development GO:0007417 123 0.110
endothelial cell migration GO:0043542 86 0.108
Mouse
ossification involved in bone maturation GO:0043931 4 0.104
cell adhesion GO:0007155 325 0.104
Human
positive regulation of cell proliferation GO:0008284 301 0.103
Human
head development GO:0060322 108 0.102
regulation of chemotaxis GO:0050920 74 0.101
neuron differentiation GO:0030182 138 0.101
regulation of cellular amine metabolic process GO:0033238 11 0.101
regulation of cell growth GO:0001558 135 0.101
immune response GO:0006955 307 0.100
cellular response to dna damage stimulus GO:0006974 379 0.099
cellular ketone metabolic process GO:0042180 80 0.099
regulation of cell development GO:0060284 161 0.098
regulation of neuron differentiation GO:0045664 70 0.096
phosphatidylinositol mediated signaling GO:0048015 55 0.094
regulation of vasculature development GO:1901342 97 0.094
Mouse
regulation of cellular component size GO:0032535 82 0.093
regulation of angiogenesis GO:0045765 92 0.092
Mouse
regulation of cell projection organization GO:0031344 107 0.091
regulation of response to external stimulus GO:0032101 222 0.090
negative regulation of vasculature development GO:1901343 43 0.089
cell growth GO:0016049 160 0.088
positive regulation of cell projection organization GO:0031346 64 0.087
regulation of ras gtpase activity GO:0032318 128 0.086
neurogenesis GO:0022008 169 0.084
formation of primary germ layer GO:0001704 42 0.083
regulation of extent of cell growth GO:0061387 9 0.083
neuron projection extension GO:1990138 14 0.082
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.081
negative regulation of developmental process GO:0051093 247 0.079
positive regulation of neurogenesis GO:0050769 49 0.079
hematopoietic or lymphoid organ development GO:0048534 186 0.078
regulation of cellular ketone metabolic process GO:0010565 50 0.078
post embryonic development GO:0009791 2 0.077
cellular amino acid metabolic process GO:0006520 116 0.077
amine metabolic process GO:0009308 44 0.076
regulation of stress activated mapk cascade GO:0032872 84 0.076
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.074
regulation of behavior GO:0050795 82 0.074
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.073
regulation of cellular response to stress GO:0080135 244 0.072
olfactory lobe development GO:0021988 5 0.070
negative regulation of cellular component movement GO:0051271 106 0.070
Human
response to light stimulus GO:0009416 87 0.069
regulation of endothelial cell migration GO:0010594 67 0.069
skeletal system development GO:0001501 79 0.069
epithelium migration GO:0090132 119 0.068
Mouse
organ maturation GO:0048799 5 0.068
behavior GO:0007610 112 0.067
positive regulation of growth GO:0045927 58 0.067
regulation of anatomical structure size GO:0090066 101 0.067
tube morphogenesis GO:0035239 95 0.066
Mouse
negative regulation of dephosphorylation GO:0035305 63 0.066
regulation of response to dna damage stimulus GO:2001020 94 0.065
regulation of phosphatase activity GO:0010921 81 0.065
regulation of neurogenesis GO:0050767 82 0.064
guanosine containing compound catabolic process GO:1901069 239 0.064
Human
regulation of dephosphorylation GO:0035303 96 0.062
regulation of mapk cascade GO:0043408 262 0.062
vesicle mediated transport GO:0016192 371 0.060
positive regulation of axonogenesis GO:0050772 9 0.060
negative regulation of angiogenesis GO:0016525 39 0.059
axon extension GO:0048675 13 0.058
negative regulation of protein metabolic process GO:0051248 391 0.057
regulation of neuron projection development GO:0010975 57 0.057
regulation of cellular amino acid metabolic process GO:0006521 6 0.057
positive regulation of cellular amine metabolic process GO:0033240 7 0.057
determination of adult lifespan GO:0008340 2 0.056
regulation of establishment of protein localization GO:0070201 242 0.055
tissue migration GO:0090130 119 0.055
Mouse
immune effector process GO:0002252 159 0.055
immune system development GO:0002520 195 0.054
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.053
positive regulation of neuron differentiation GO:0045666 40 0.053
chemotaxis GO:0006935 157 0.052
Human
hemopoiesis GO:0030097 180 0.052
ameboidal type cell migration GO:0001667 135 0.052
Mouse
gland development GO:0048732 48 0.052
Mouse
stress activated protein kinase signaling cascade GO:0031098 94 0.051
cell activation GO:0001775 213 0.051
regulation of nervous system development GO:0051960 88 0.051
generation of neurons GO:0048699 152 0.051
axon extension involved in axon guidance GO:0048846 5 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
cell part morphogenesis GO:0032990 137 0.049
leukocyte aggregation GO:0070486 8 0.049
multicellular organismal aging GO:0010259 3 0.048
positive regulation of nervous system development GO:0051962 54 0.048
tube development GO:0035295 125 0.046
Mouse
positive chemotaxis GO:0050918 33 0.046
Human
response to oxygen containing compound GO:1901700 369 0.044
cell projection morphogenesis GO:0048858 129 0.044
t helper cell differentiation GO:0042093 4 0.044
regulation of axonogenesis GO:0050770 16 0.043
cell substrate adhesion GO:0031589 132 0.043
regulation of cytoskeleton organization GO:0051493 177 0.043
Human
neuron development GO:0048666 113 0.042
inositol lipid mediated signaling GO:0048017 55 0.042
telencephalon development GO:0021537 17 0.041
developmental cell growth GO:0048588 18 0.039
regulation of axon extension GO:0030516 7 0.039
leukocyte differentiation GO:0002521 98 0.039
nucleoside monophosphate metabolic process GO:0009123 191 0.038
intracellular protein transport GO:0006886 270 0.038
single organism membrane organization GO:0044802 268 0.037
defense response GO:0006952 315 0.037
organonitrogen compound biosynthetic process GO:1901566 200 0.037
regulation of secretion by cell GO:1903530 177 0.036
anatomical structure maturation GO:0071695 9 0.036
cell fate determination GO:0001709 3 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.036
regulation of protein transport GO:0051223 213 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.035
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.035
single organism cellular localization GO:1902580 332 0.034
growth GO:0040007 202 0.034
negative regulation of cellular component organization GO:0051129 235 0.034
purine nucleoside monophosphate metabolic process GO:0009126 186 0.034
regulation of cell morphogenesis GO:0022604 153 0.034
Human
basement membrane organization GO:0071711 3 0.034
response to wounding GO:0009611 168 0.034
negative regulation of cell proliferation GO:0008285 228 0.033
secretion GO:0046903 254 0.033
endoderm development GO:0007492 33 0.033
regulation of protein localization GO:0032880 296 0.032
regulation of proteolysis GO:0030162 293 0.032
positive regulation of transport GO:0051050 336 0.032
neurological system process GO:0050877 163 0.032
cytoplasmic transport GO:0016482 379 0.032
positive regulation of programmed cell death GO:0043068 249 0.031
negative regulation of protein modification process GO:0031400 200 0.031
regulation of peptidase activity GO:0052547 180 0.031
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.031
protein oligomerization GO:0051259 173 0.030
patterning of blood vessels GO:0001569 2 0.030
Mouse
regulation of developmental growth GO:0048638 30 0.030
cell junction assembly GO:0034329 67 0.029
system process GO:0003008 349 0.029
multicellular organismal macromolecule metabolic process GO:0044259 29 0.029
sprouting angiogenesis GO:0002040 29 0.029
t cell activation GO:0042110 99 0.029
extracellular structure organization GO:0043062 41 0.028
carbohydrate derivative biosynthetic process GO:1901137 207 0.028
mesenchymal cell differentiation GO:0048762 52 0.028
oxidation reduction process GO:0055114 396 0.028
microtubule cytoskeleton organization GO:0000226 176 0.028
leukocyte activation GO:0045321 164 0.027
secretion by cell GO:0032940 226 0.027
gastrulation GO:0007369 51 0.027
positive regulation of cellular component biogenesis GO:0044089 158 0.027
membrane organization GO:0061024 292 0.027
collagen metabolic process GO:0032963 28 0.027
cellular lipid metabolic process GO:0044255 303 0.027
regeneration GO:0031099 4 0.027
t helper 1 type immune response GO:0042088 8 0.027
cell recognition GO:0008037 9 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
rhythmic behavior GO:0007622 2 0.026
multicellular organismal metabolic process GO:0044236 34 0.026
extracellular matrix organization GO:0030198 41 0.026
stem cell differentiation GO:0048863 93 0.026
tissue morphogenesis GO:0048729 96 0.025
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.025
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
neuron projection development GO:0031175 106 0.025
mesenchyme development GO:0060485 59 0.025
neural crest cell migration GO:0001755 2 0.025
developmental growth GO:0048589 48 0.025
cell activation involved in immune response GO:0002263 30 0.025
negative regulation of organelle organization GO:0010639 126 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
oogenesis GO:0048477 2 0.024
female gamete generation GO:0007292 2 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
lymphocyte activation GO:0046649 133 0.024
endomembrane system organization GO:0010256 196 0.024
lipid metabolic process GO:0006629 381 0.024
memory GO:0007613 3 0.024
transmembrane transport GO:0055085 399 0.023
protein localization to organelle GO:0033365 280 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
adaptive immune response GO:0002250 49 0.023
neuron projection extension involved in neuron projection guidance GO:1902284 5 0.023
microtubule based process GO:0007017 210 0.023
positive regulation of protein transport GO:0051222 135 0.023
sensory perception of smell GO:0007608 2 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.023
innate immune response GO:0045087 178 0.023
digestive tract development GO:0048565 75 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
circadian behavior GO:0048512 2 0.023
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
axonogenesis GO:0007409 31 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
wnt signaling pathway GO:0016055 156 0.022
protein targeting GO:0006605 187 0.022
protein localization to membrane GO:0072657 160 0.022
glycerolipid metabolic process GO:0046486 107 0.022
neuroblast proliferation GO:0007405 4 0.022
plasma membrane organization GO:0007009 115 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.021
brain development GO:0007420 97 0.021
atp catabolic process GO:0006200 157 0.021
adult behavior GO:0030534 18 0.021
positive regulation of cell death GO:0010942 263 0.021
positive regulation of organelle organization GO:0010638 195 0.021
covalent chromatin modification GO:0016569 254 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
epithelial cell differentiation GO:0030855 141 0.021
establishment of protein localization to membrane GO:0090150 121 0.021
neural crest cell development GO:0014032 3 0.021
peptidyl tyrosine modification GO:0018212 170 0.021
digestive system development GO:0055123 75 0.020
protein maturation GO:0051604 233 0.020
response to cytokine GO:0034097 232 0.020
protein catabolic process GO:0030163 325 0.020
single organism cell adhesion GO:0098602 179 0.020
muscle cell differentiation GO:0042692 63 0.020
actin filament based process GO:0030029 224 0.020
leukocyte activation involved in immune response GO:0002366 30 0.020
cell matrix adhesion GO:0007160 85 0.020
response to nitrogen compound GO:1901698 184 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
neuron projection morphogenesis GO:0048812 50 0.020
regulation of cell cycle GO:0051726 393 0.020
blastoderm segmentation GO:0007350 2 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
response to organonitrogen compound GO:0010243 156 0.019
digestive tract morphogenesis GO:0048546 56 0.019
endothelial cell proliferation GO:0001935 65 0.019
Human
forebrain development GO:0030900 26 0.019
neuromuscular junction development GO:0007528 3 0.019
segmentation GO:0035282 4 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.019
regulation of cell shape GO:0008360 48 0.019
Human
nitrogen compound transport GO:0071705 191 0.019
positive regulation of wnt signaling pathway GO:0030177 54 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.018
hindbrain development GO:0030902 3 0.018
apoptotic signaling pathway GO:0097190 268 0.018
focal adhesion assembly GO:0048041 30 0.018
regulation of immune response GO:0050776 201 0.018
stem cell development GO:0048864 69 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
protein processing GO:0016485 226 0.018
atp metabolic process GO:0046034 176 0.018
cell junction organization GO:0034330 79 0.018
wound healing GO:0042060 115 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
azole transport GO:0045117 4 0.018
positive regulation of secretion GO:0051047 116 0.018
small molecule biosynthetic process GO:0044283 157 0.017
t cell differentiation GO:0030217 29 0.017
endoderm formation GO:0001706 33 0.017
cell projection assembly GO:0030031 126 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
chromatin organization GO:0006325 351 0.017
positive regulation of neuron projection development GO:0010976 34 0.017
positive regulation of axon extension GO:0045773 4 0.017
dendrite development GO:0016358 24 0.017
lymphocyte differentiation GO:0030098 35 0.017
regulation of secretion GO:0051046 194 0.017
long chain fatty acid metabolic process GO:0001676 30 0.017
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
regulation of protein stability GO:0031647 87 0.016
response to water GO:0009415 2 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
negative regulation of cell motility GO:2000146 104 0.016
Human
alpha beta t cell differentiation GO:0046632 7 0.016
developmental maturation GO:0021700 28 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
regulation of protein secretion GO:0050708 86 0.016
developmental growth involved in morphogenesis GO:0060560 23 0.016
actin filament organization GO:0007015 128 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
glycerophospholipid metabolic process GO:0006650 84 0.015
protein localization to plasma membrane GO:0072659 93 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
anion transport GO:0006820 161 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
histone modification GO:0016570 251 0.015
nuclear transport GO:0051169 179 0.015
regulation of microtubule cytoskeleton organization GO:0070507 61 0.015
epithelial to mesenchymal transition GO:0001837 48 0.015
sensory perception GO:0007600 103 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
maintenance of cell polarity GO:0030011 2 0.015
positive regulation of cytokine production GO:0001819 167 0.015
response to transforming growth factor beta GO:0071559 94 0.015
oocyte development GO:0048599 1 0.015
cellular protein catabolic process GO:0044257 261 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
anterior posterior axis specification GO:0009948 2 0.015
retina vasculature development in camera type eye GO:0061298 3 0.015
negative regulation of cell death GO:0060548 345 0.015
chemical homeostasis GO:0048878 306 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.015
endochondral bone morphogenesis GO:0060350 3 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
protein localization to nucleus GO:0034504 136 0.014
cerebellum development GO:0021549 2 0.014
cellular protein complex assembly GO:0043623 188 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
regulation of microtubule based process GO:0032886 74 0.014
chromatin modification GO:0016568 298 0.014
epithelium development GO:0060429 227 0.014
Mouse
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of protein kinase activity GO:0045859 289 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
response to growth factor GO:0070848 205 0.014
cellular chemical homeostasis GO:0055082 180 0.014
endothelium development GO:0003158 33 0.014
regulation of protein catabolic process GO:0042176 155 0.014
lipid biosynthetic process GO:0008610 177 0.014
regulation of body fluid levels GO:0050878 99 0.014
regulation of intracellular transport GO:0032386 195 0.014
actin cytoskeleton organization GO:0030036 207 0.014
peripheral nervous system development GO:0007422 2 0.014
negative regulation of locomotion GO:0040013 118 0.014
Human
establishment of protein localization to plasma membrane GO:0090002 68 0.014
leukocyte migration GO:0050900 107 0.013
negative regulation of proteolysis GO:0045861 132 0.013
anatomical structure homeostasis GO:0060249 100 0.013
regulation of kinase activity GO:0043549 314 0.013
positive regulation of immune response GO:0050778 159 0.013
lymphocyte activation involved in immune response GO:0002285 20 0.013
cation homeostasis GO:0055080 189 0.013
response to hormone GO:0009725 175 0.013
protein stabilization GO:0050821 64 0.013
oocyte differentiation GO:0009994 2 0.013
protein secretion GO:0009306 98 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
negative regulation of cell migration GO:0030336 102 0.013
Human
regulation of meiotic cell cycle GO:0051445 4 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.013
motor neuron axon guidance GO:0008045 2 0.013
negative regulation of catabolic process GO:0009895 104 0.013
Human
negative regulation of phosphorylation GO:0042326 174 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
positive regulation of peptidase activity GO:0010952 88 0.013
muscle organ development GO:0007517 56 0.013
regulation of cell projection assembly GO:0060491 47 0.013

PLXND1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.300
eye and adnexa disease DOID:1492 150 0.300
nervous system disease DOID:863 431 0.300
eye disease DOID:5614 149 0.300
retinal disease DOID:5679 118 0.258
retinal degeneration DOID:8466 89 0.258
musculoskeletal system disease DOID:17 223 0.174
myopathy DOID:423 104 0.126
congenital muscular dystrophy DOID:0050557 22 0.126
muscular disease DOID:0080000 114 0.126
muscular dystrophy DOID:9884 51 0.126
muscle tissue disease DOID:66 113 0.126
osteochondrodysplasia DOID:2256 35 0.117
bone development disease DOID:0080006 55 0.117
bone disease DOID:0080001 88 0.117
connective tissue disease DOID:65 109 0.117
retinitis pigmentosa DOID:10584 51 0.066
osteogenesis imperfecta DOID:12347 13 0.042
disease of metabolism DOID:0014667 295 0.035
cone rod dystrophy DOID:0050572 18 0.033
inherited metabolic disorder DOID:655 242 0.020
central nervous system disease DOID:331 186 0.015
neurodegenerative disease DOID:1289 102 0.014