Homo sapiens

20 known processes

METAP2

methionyl aminopeptidase 2

(Aliases: MAP2,MNPEP,p67eIF2,p67)

METAP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.506
cellular macromolecular complex assembly GO:0034622 324 0.215
vesicle mediated transport GO:0016192 371 0.181
Worm
rna processing GO:0006396 255 0.146
female gamete generation GO:0007292 2 0.103
chromatin modification GO:0016568 298 0.103
ribonucleoprotein complex assembly GO:0022618 78 0.094
ribonucleoprotein complex biogenesis GO:0022613 116 0.089
endocytosis GO:0006897 159 0.088
Worm
ncrna metabolic process GO:0034660 108 0.076
regulation of meiotic cell cycle GO:0051445 4 0.068
oogenesis GO:0048477 2 0.067
mitotic cell cycle process GO:1903047 286 0.066
single organism cellular localization GO:1902580 332 0.064
ncrna processing GO:0034470 83 0.059
negative regulation of catalytic activity GO:0043086 335 0.051
histone modification GO:0016570 251 0.050
chromatin organization GO:0006325 351 0.047
mitotic cell cycle GO:0000278 326 0.046
immune response GO:0006955 307 0.044
cell morphogenesis GO:0000902 296 0.039
developmental process involved in reproduction GO:0003006 66 0.039
Worm
protein oligomerization GO:0051259 173 0.038
posttranscriptional regulation of gene expression GO:0010608 213 0.037
response to abiotic stimulus GO:0009628 336 0.037
multicellular organismal aging GO:0010259 3 0.037
negative regulation of cell cycle GO:0045786 193 0.036
amine metabolic process GO:0009308 44 0.036
regulation of cell cycle process GO:0010564 266 0.035
response to other organism GO:0051707 261 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
receptor mediated endocytosis GO:0006898 84 0.035
Worm
nucleoside catabolic process GO:0009164 408 0.035
regulation of cell differentiation GO:0045595 393 0.034
ribosome biogenesis GO:0042254 48 0.033
reproductive process GO:0022414 106 0.033
Worm
cellular amine metabolic process GO:0044106 41 0.033
protein localization to organelle GO:0033365 280 0.032
nervous system development GO:0007399 293 0.032
cytoplasmic transport GO:0016482 379 0.032
sex differentiation GO:0007548 45 0.031
Worm
cell cycle phase transition GO:0044770 173 0.031
negative regulation of mitotic cell cycle GO:0045930 102 0.031
protein maturation GO:0051604 233 0.031
covalent chromatin modification GO:0016569 254 0.030
ribonucleoprotein complex subunit organization GO:0071826 81 0.030
regulation of meiosis GO:0040020 3 0.029
positive regulation of cellular component organization GO:0051130 376 0.029
regulation of transferase activity GO:0051338 355 0.029
protein processing GO:0016485 226 0.029
cell development GO:0048468 328 0.028
reproduction GO:0000003 63 0.028
Worm
cellular amino acid metabolic process GO:0006520 116 0.027
determination of adult lifespan GO:0008340 2 0.027
nuclear transport GO:0051169 179 0.027
cell division GO:0051301 168 0.025
innate immune response GO:0045087 178 0.025
translation GO:0006412 132 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
mrna metabolic process GO:0016071 175 0.025
peptidyl lysine modification GO:0018205 144 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
response to external biotic stimulus GO:0043207 261 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
regulation of cell cycle GO:0051726 393 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
regulation of proteolysis GO:0030162 293 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
positive regulation of cell death GO:0010942 263 0.022
cellular component morphogenesis GO:0032989 314 0.022
protein modification by small protein removal GO:0070646 92 0.021
embryo development GO:0009790 123 0.021
Worm
peptidyl lysine acetylation GO:0018394 101 0.021
regulation of translation GO:0006417 89 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
response to cytokine GO:0034097 232 0.020
cell projection organization GO:0030030 252 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
regulation of chromosome organization GO:0033044 103 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
system process GO:0003008 349 0.019
reproductive structure development GO:0048608 55 0.019
Worm
regulation of cellular component movement GO:0051270 334 0.019
response to biotic stimulus GO:0009607 276 0.019
negative regulation of cell cycle process GO:0010948 121 0.019
cellular macromolecule catabolic process GO:0044265 380 0.018
positive regulation of chromosome organization GO:2001252 41 0.018
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.018
negative regulation of programmed cell death GO:0043069 321 0.017
regeneration GO:0031099 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
regulation of response to dna damage stimulus GO:2001020 94 0.017
cell cycle checkpoint GO:0000075 117 0.017
cell growth GO:0016049 160 0.017
internal protein amino acid acetylation GO:0006475 101 0.017
organelle fission GO:0048285 149 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
development of primary sexual characteristics GO:0045137 35 0.017
Worm
regulation of locomotion GO:0040012 329 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
nuclear division GO:0000280 128 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
spermatid development GO:0007286 4 0.016
behavior GO:0007610 112 0.016
intracellular protein transport GO:0006886 270 0.016
reproductive system development GO:0061458 56 0.016
Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.016
negative regulation of cell cycle phase transition GO:1901988 89 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
negative regulation of cell death GO:0060548 345 0.015
regulation of kinase activity GO:0043549 314 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
defense response GO:0006952 315 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
positive regulation of transferase activity GO:0051347 227 0.015
growth GO:0040007 202 0.015
internal peptidyl lysine acetylation GO:0018393 97 0.014
rna interference GO:0016246 4 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
apoptotic signaling pathway GO:0097190 268 0.014
microtubule based process GO:0007017 210 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
regulation of protein kinase activity GO:0045859 289 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
protein catabolic process GO:0030163 325 0.013
nuclear import GO:0051170 106 0.013
embryo development ending in birth or egg hatching GO:0009792 34 0.013
Worm
negative regulation of protein processing GO:0010955 142 0.013
regulation of cellular response to stress GO:0080135 244 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
locomotory behavior GO:0007626 1 0.013
multicellular organismal reproductive process GO:0048609 40 0.013
Worm
signal transduction by phosphorylation GO:0023014 297 0.013
neuromuscular junction development GO:0007528 3 0.013
regulation of mitotic spindle checkpoint GO:1903504 8 0.013
regulation of peptidase activity GO:0052547 180 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
neurogenesis GO:0022008 169 0.013
dephosphorylation GO:0016311 209 0.013
chromatin assembly or disassembly GO:0006333 78 0.013
negative regulation of developmental process GO:0051093 247 0.013
organelle assembly GO:0070925 176 0.013
positive regulation of organelle organization GO:0010638 195 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
segmentation GO:0035282 4 0.012
tissue regeneration GO:0042246 3 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
cell activation GO:0001775 213 0.012
protein import GO:0017038 130 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
mitotic dna integrity checkpoint GO:0044774 30 0.012
regulation of protein maturation GO:1903317 150 0.012
rna localization GO:0006403 41 0.012
positive regulation of meiotic cell cycle GO:0051446 2 0.012
regulation of cell migration GO:0030334 289 0.012
oocyte development GO:0048599 1 0.012
somitogenesis GO:0001756 2 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of cell growth GO:0001558 135 0.011
positive regulation of immune response GO:0050778 159 0.011
positive regulation of dna metabolic process GO:0051054 73 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
cell part morphogenesis GO:0032990 137 0.011
oocyte differentiation GO:0009994 2 0.011
response to organic cyclic compound GO:0014070 204 0.011
regulation of protein processing GO:0070613 150 0.011
epithelial cell proliferation GO:0050673 128 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
maturation of lsu rrna GO:0000470 3 0.010
immune system development GO:0002520 195 0.010
purine containing compound catabolic process GO:0072523 411 0.010
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 3 0.010
response to bacterium GO:0009617 144 0.010
regulation of dna metabolic process GO:0051052 153 0.010
single organism reproductive process GO:0044702 98 0.010
Worm

METAP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.010
cancer DOID:162 167 0.010