Homo sapiens

179 known processes

MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

(Aliases: HNGS1,MRE11,ATLD,MRE11B)

MRE11A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein autophosphorylation GO:0031952 15 1.000
telomere capping GO:0016233 5 1.000
Fly
double strand break repair GO:0006302 101 0.999
Yeast Mouse
dna repair GO:0006281 198 0.999
Yeast Mouse
cellular response to dna damage stimulus GO:0006974 379 0.999
replication fork processing GO:0031297 13 0.996
telomere maintenance via telomere lengthening GO:0010833 9 0.989
nucleotide excision repair GO:0006289 31 0.988
dna geometric change GO:0032392 32 0.976
dna double strand break processing GO:0000729 10 0.971
Yeast
double strand break repair via single strand annealing GO:0045002 4 0.963
v d j recombination GO:0033151 3 0.959
g2 dna damage checkpoint GO:0031572 26 0.951
Mouse Fly
cell cycle checkpoint GO:0000075 117 0.948
Mouse Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.944
regulation of cellular response to stress GO:0080135 244 0.922
isotype switching GO:0045190 3 0.921
double strand break repair via homologous recombination GO:0000724 50 0.917
Yeast
negative regulation of cell cycle GO:0045786 193 0.898
g2 m transition of mitotic cell cycle GO:0000086 41 0.884
blastocyst development GO:0001824 3 0.881
signal transduction in response to dna damage GO:0042770 57 0.878
dna damage induced protein phosphorylation GO:0006975 5 0.846
dna conformation change GO:0071103 113 0.779
purine nucleotide catabolic process GO:0006195 405 0.761
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.751
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.727
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.723
positive regulation of kinase activity GO:0033674 204 0.715
organelle fission GO:0048285 149 0.712
Yeast Mouse Worm
dna catabolic process exonucleolytic GO:0000738 17 0.708
Yeast
intrinsic apoptotic signaling pathway GO:0097193 127 0.695
covalent chromatin modification GO:0016569 254 0.687
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.680
meiotic chromosome segregation GO:0045132 4 0.677
Worm
response to ionizing radiation GO:0010212 65 0.650
nucleoside catabolic process GO:0009164 408 0.639
regulation of mitotic cell cycle GO:0007346 189 0.638
Mouse Worm Fly
regulation of response to dna damage stimulus GO:2001020 94 0.593
regulation of double strand break repair GO:2000779 22 0.576
regulation of cell cycle GO:0051726 393 0.570
telomere maintenance via telomerase GO:0007004 8 0.565
dna damage checkpoint GO:0000077 68 0.546
Mouse Fly
ribonucleoside catabolic process GO:0042454 406 0.539
ribonucleotide catabolic process GO:0009261 405 0.527
negative regulation of mitotic cell cycle GO:0045930 102 0.525
Mouse Worm Fly
neuromuscular process controlling balance GO:0050885 7 0.518
response to radiation GO:0009314 151 0.516
telomere maintenance GO:0000723 32 0.503
Fly
dna catabolic process endonucleolytic GO:0000737 37 0.474
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 412 0.466
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.458
cell cycle arrest GO:0007050 71 0.444
response to nitrogen compound GO:1901698 184 0.440
chromosome segregation GO:0007059 114 0.427
positive regulation of telomere maintenance GO:0032206 4 0.422
purine nucleoside triphosphate catabolic process GO:0009146 392 0.412
dna integrity checkpoint GO:0031570 71 0.389
Mouse Fly
dna duplex unwinding GO:0032508 30 0.386
regulation of kinase activity GO:0043549 314 0.384
response to abiotic stimulus GO:0009628 336 0.381
mitotic cell cycle process GO:1903047 286 0.377
Mouse Fly
cardiovascular system development GO:0072358 262 0.367
response to gamma radiation GO:0010332 14 0.357
signal transduction by phosphorylation GO:0023014 297 0.357
dna catabolic process GO:0006308 49 0.354
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.344
atp metabolic process GO:0046034 176 0.342
negative regulation of cell cycle process GO:0010948 121 0.339
purine ribonucleoside catabolic process GO:0046130 398 0.338
somatic diversification of immunoglobulins GO:0016445 6 0.331
telomere maintenance via recombination GO:0000722 4 0.329
telomere organization GO:0032200 33 0.303
Fly
mitotic g2 m transition checkpoint GO:0044818 9 0.294
Mouse Fly
mitotic dna integrity checkpoint GO:0044774 30 0.294
Mouse Fly
dna recombination GO:0006310 77 0.290
Yeast
mitotic recombination GO:0006312 8 0.288
purine nucleoside monophosphate catabolic process GO:0009128 158 0.281
positive regulation of dna damage response signal transduction by p53 class mediator GO:0043517 8 0.277
purine ribonucleotide catabolic process GO:0009154 404 0.272
positive regulation of protein autophosphorylation GO:0031954 9 0.272
cellular response to abiotic stimulus GO:0071214 117 0.268
anatomical structure homeostasis GO:0060249 100 0.267
Fly
rna dependent dna replication GO:0006278 16 0.264
purine nucleoside monophosphate metabolic process GO:0009126 186 0.260
protein maturation GO:0051604 233 0.255
mitotic dna damage checkpoint GO:0044773 28 0.248
Mouse Fly
positive regulation of protein phosphorylation GO:0001934 313 0.245
positive regulation of phosphorylation GO:0042327 394 0.243
mapk cascade GO:0000165 288 0.239
negative regulation of cell death GO:0060548 345 0.237
nuclear division GO:0000280 128 0.234
Yeast Mouse Worm
nucleoside triphosphate catabolic process GO:0009143 394 0.228
negative regulation of glial cell apoptotic process GO:0034351 6 0.227
mitotic cell cycle phase transition GO:0044772 162 0.224
Mouse Fly
nucleosome assembly GO:0006334 50 0.218
positive regulation of transferase activity GO:0051347 227 0.207
cellular macromolecule catabolic process GO:0044265 380 0.204
Yeast
leukocyte activation involved in immune response GO:0002366 30 0.197
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.191
organophosphate catabolic process GO:0046434 430 0.189
negative regulation of apoptotic process GO:0043066 316 0.186
regulation of cell cycle phase transition GO:1901987 126 0.182
Mouse Fly
lymphocyte activation GO:0046649 133 0.182
mitotic dna replication checkpoint GO:0033314 2 0.179
oocyte differentiation GO:0009994 2 0.178
growth GO:0040007 202 0.177
purine nucleoside catabolic process GO:0006152 398 0.177
signal transduction involved in dna damage checkpoint GO:0072422 15 0.175
chordate embryonic development GO:0043009 34 0.172
regulation of dna recombination GO:0000018 23 0.167
negative regulation of developmental process GO:0051093 247 0.165
immune response GO:0006955 307 0.165
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.163
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.160
neuromuscular process GO:0050905 15 0.156
regulation of proteolysis GO:0030162 293 0.156
leukocyte mediated immunity GO:0002443 59 0.155
histone h3 k4 methylation GO:0051568 27 0.154
histone h2a phosphorylation GO:1990164 3 0.153
regulation of leukocyte activation GO:0002694 115 0.147
nucleoside monophosphate metabolic process GO:0009123 191 0.146
mitotic g2 dna damage checkpoint GO:0007095 7 0.145
Mouse Fly
positive regulation of cell cycle GO:0045787 140 0.143
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.141
negative regulation of protein processing GO:0010955 142 0.141
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.137
response to uv GO:0009411 73 0.133
lipoprotein catabolic process GO:0042159 1 0.132
viral life cycle GO:0019058 132 0.132
positive regulation of programmed cell death GO:0043068 249 0.130
apoptotic signaling pathway GO:0097190 268 0.123
regulation of dna repair GO:0006282 47 0.122
protein homooligomerization GO:0051260 100 0.120
negative regulation of cellular protein catabolic process GO:1903363 38 0.119
positive regulation of cellular component biogenesis GO:0044089 158 0.118
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.112
lymphocyte mediated immunity GO:0002449 48 0.108
regulation of lymphocyte activation GO:0051249 103 0.107
regulation of transferase activity GO:0051338 355 0.106
segmentation GO:0035282 4 0.102
regulation of mitotic cell cycle phase transition GO:1901990 118 0.102
Mouse Fly
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.101
Yeast
regulation of cell cycle process GO:0010564 266 0.101
system process GO:0003008 349 0.098
morphogenesis of an epithelium GO:0002009 60 0.098
chromosome separation GO:0051304 23 0.097
negative regulation of cellular amine metabolic process GO:0033239 3 0.095
stress activated mapk cascade GO:0051403 93 0.095
dna replication independent nucleosome organization GO:0034724 27 0.094
spindle assembly checkpoint GO:0071173 17 0.092
cellular response to ionizing radiation GO:0071479 32 0.085
adaptive immune response GO:0002250 49 0.084
somatic cell dna recombination GO:0016444 6 0.084
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.083
mismatch repair GO:0006298 15 0.081
neuron death GO:0070997 65 0.081
glycerolipid metabolic process GO:0046486 107 0.081
dna replication GO:0006260 116 0.080
cell activation involved in immune response GO:0002263 30 0.079
regulation of protein maturation GO:1903317 150 0.079
cell cycle phase transition GO:0044770 173 0.079
Mouse Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.077
Mouse Fly
nucleotide catabolic process GO:0009166 408 0.076
intra s dna damage checkpoint GO:0031573 4 0.075
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.073
interstrand cross link repair GO:0036297 3 0.073
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 3 0.073
purine containing compound catabolic process GO:0072523 411 0.072
leukocyte differentiation GO:0002521 98 0.070
leukocyte activation GO:0045321 164 0.069
nucleoside phosphate catabolic process GO:1901292 412 0.069
double strand break repair via nonhomologous end joining GO:0006303 10 0.068
Yeast
response to oxygen containing compound GO:1901700 369 0.068
replicative senescence GO:0090399 8 0.067
positive regulation of helicase activity GO:0051096 6 0.066
regulation of double strand break repair via homologous recombination GO:0010569 11 0.066
glycosyl compound catabolic process GO:1901658 413 0.066
negative regulation of proteolysis GO:0045861 132 0.066
response to oxidative stress GO:0006979 121 0.065
cell activation GO:0001775 213 0.065
somatic diversification of immune receptors GO:0002200 8 0.065
purine ribonucleoside metabolic process GO:0046128 437 0.065
regulation of neuron apoptotic process GO:0043523 35 0.064
negative regulation of organelle organization GO:0010639 126 0.064
ribonucleoside monophosphate catabolic process GO:0009158 158 0.064
regulation of chromosome segregation GO:0051983 44 0.063
chromatin modification GO:0016568 298 0.063
regulation of transcription by chromatin organization GO:0034401 1 0.063
response to biotic stimulus GO:0009607 276 0.062
mitochondrion organization GO:0007005 156 0.060
negative regulation of cellular protein metabolic process GO:0032269 353 0.060
response to organonitrogen compound GO:0010243 156 0.060
dna templated transcription initiation GO:0006352 35 0.060
chromatin organization GO:0006325 351 0.060
brain development GO:0007420 97 0.060
dna replication independent nucleosome assembly GO:0006336 27 0.059
determination of adult lifespan GO:0008340 2 0.059
mitotic cell cycle GO:0000278 326 0.059
Mouse Worm Fly
immune system development GO:0002520 195 0.058
positive regulation of chromosome organization GO:2001252 41 0.057
negative regulation of histone h3 k9 methylation GO:0051573 3 0.057
positive regulation of cellular component organization GO:0051130 376 0.056
negative regulation of cellular catabolic process GO:0031330 83 0.056
ubiquitin dependent protein catabolic process GO:0006511 206 0.056
regulation of protein catabolic process GO:0042176 155 0.055
cellular lipid metabolic process GO:0044255 303 0.055
negative regulation of catabolic process GO:0009895 104 0.055
negative regulation of hematopoietic progenitor cell differentiation GO:1901533 18 0.054
regulation of cellular ketone metabolic process GO:0010565 50 0.054
negative regulation of protein maturation GO:1903318 142 0.054
organelle localization GO:0051640 84 0.053
female gamete generation GO:0007292 2 0.052
histone h4 acetylation GO:0043967 47 0.052
central nervous system development GO:0007417 123 0.052
negative regulation of immune system process GO:0002683 136 0.050
regulation of mapk cascade GO:0043408 262 0.050
negative regulation of protein metabolic process GO:0051248 391 0.050
regulation of dna metabolic process GO:0051052 153 0.050
male gonad development GO:0008584 23 0.050
dna packaging GO:0006323 77 0.049
production of molecular mediator of immune response GO:0002440 37 0.049
immune effector process GO:0002252 159 0.048
embryo development GO:0009790 123 0.048
Worm
neuron apoptotic process GO:0051402 39 0.048
meiosis i GO:0007127 4 0.047
Yeast Mouse
regulation of protein processing GO:0070613 150 0.047
histone methylation GO:0016571 60 0.047
mitotic spindle assembly checkpoint GO:0007094 14 0.047
histone modification GO:0016570 251 0.045
oocyte development GO:0048599 1 0.045
positive regulation of proteolysis GO:0045862 142 0.045
negative regulation of sister chromatid segregation GO:0033046 17 0.045
ras protein signal transduction GO:0007265 73 0.045
enzyme linked receptor protein signaling pathway GO:0007167 303 0.044
mitotic spindle checkpoint GO:0071174 18 0.044
spindle checkpoint GO:0031577 26 0.044
positive regulation of signal transduction by p53 class mediator GO:1901798 10 0.044
circulatory system development GO:0072359 262 0.044
negative regulation of cell proliferation GO:0008285 228 0.043
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.041
cellular response to oxygen containing compound GO:1901701 276 0.041
microtubule based process GO:0007017 210 0.040
somitogenesis GO:0001756 2 0.039
regulation of mononuclear cell proliferation GO:0032944 65 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
compound eye development GO:0048749 1 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.037
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.037
cell part morphogenesis GO:0032990 137 0.037
negative regulation of multicellular organismal process GO:0051241 317 0.037
response to purine containing compound GO:0014074 40 0.037
small gtpase mediated signal transduction GO:0007264 78 0.036
cell aging GO:0007569 52 0.036
rho protein signal transduction GO:0007266 26 0.036
regulation of protein ubiquitination GO:0031396 95 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
head development GO:0060322 108 0.035
negative regulation of dna metabolic process GO:0051053 57 0.035
negative regulation of chromosome organization GO:2001251 48 0.035
positive regulation of histone methylation GO:0031062 12 0.035
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.035
positive regulation of histone h3 k4 methylation GO:0051571 8 0.035
regulation of growth GO:0040008 165 0.035
cellular response to nitrogen compound GO:1901699 144 0.034
regulation of protein localization GO:0032880 296 0.034
cell morphogenesis GO:0000902 296 0.033
protein polyubiquitination GO:0000209 110 0.033
cell projection organization GO:0030030 252 0.033
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.033
negative regulation of dna replication GO:0008156 29 0.033
cellular amino acid metabolic process GO:0006520 116 0.032
negative regulation of meiotic cell cycle GO:0051447 2 0.032
epithelium development GO:0060429 227 0.032
positive regulation of gtpase activity GO:0043547 166 0.032
regulation of protein kinase activity GO:0045859 289 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.031
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
cilium assembly GO:0042384 63 0.031
regulation of developmental growth GO:0048638 30 0.031
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.030
protein autophosphorylation GO:0046777 123 0.030
macromolecule methylation GO:0043414 97 0.030
stem cell development GO:0048864 69 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.029
gliogenesis GO:0042063 21 0.029
methylation GO:0032259 106 0.029
regulation of viral process GO:0050792 103 0.029
lipid biosynthetic process GO:0008610 177 0.029
b cell activation GO:0042113 33 0.029
regulation of cellular component biogenesis GO:0044087 281 0.028
regulation of protein complex assembly GO:0043254 147 0.028
peptidyl serine modification GO:0018209 106 0.028
lymphocyte activation involved in immune response GO:0002285 20 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.027
protein alkylation GO:0008213 74 0.027
regulation of telomere maintenance GO:0032204 13 0.027
multi organism reproductive process GO:0044703 54 0.026
Yeast
glycerolipid biosynthetic process GO:0045017 51 0.026
peptidyl serine phosphorylation GO:0018105 101 0.026
single organism cellular localization GO:1902580 332 0.026
dna dependent dna replication GO:0006261 44 0.026
vasculature development GO:0001944 181 0.026
rna splicing GO:0008380 131 0.026
cell cycle g2 m phase transition GO:0044839 43 0.026
regulation of stress activated mapk cascade GO:0032872 84 0.025
protein localization to organelle GO:0033365 280 0.025
lymphocyte differentiation GO:0030098 35 0.025
regulation of signal transduction by p53 class mediator GO:1901796 26 0.025
cellular component morphogenesis GO:0032989 314 0.025
protein processing GO:0016485 226 0.024
response to oxygen levels GO:0070482 100 0.024
detection of muramyl dipeptide GO:0032498 1 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.024
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
positive regulation of homeostatic process GO:0032846 47 0.024
neuron remodeling GO:0016322 2 0.024
regeneration GO:0031099 4 0.023
mitotic nuclear division GO:0007067 119 0.023
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.023
regulation of dna replication GO:0006275 68 0.023
cellular amine metabolic process GO:0044106 41 0.023
mitotic cell cycle checkpoint GO:0007093 68 0.023
Mouse Fly
atp catabolic process GO:0006200 157 0.023
organophosphate biosynthetic process GO:0090407 163 0.022
intracellular protein transport GO:0006886 270 0.022
negative regulation of cell cycle phase transition GO:1901988 89 0.022
Mouse Fly
secretion GO:0046903 254 0.022
rna processing GO:0006396 255 0.022
pattern specification process GO:0007389 43 0.022
carboxylic acid biosynthetic process GO:0046394 97 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
response to external biotic stimulus GO:0043207 261 0.022
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.021
response to nutrient levels GO:0031667 81 0.021
response to organic cyclic compound GO:0014070 204 0.021
regulation of gtp catabolic process GO:0033124 180 0.021
positive regulation of cell death GO:0010942 263 0.021
cellular ketone metabolic process GO:0042180 80 0.021
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.021
response to inorganic substance GO:0010035 127 0.021
cellular response to peptide hormone stimulus GO:0071375 56 0.020
negative regulation of defense response GO:0031348 47 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
actin filament based process GO:0030029 224 0.020
amine metabolic process GO:0009308 44 0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.020
oxidation reduction process GO:0055114 396 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
positive regulation of protein localization to nucleus GO:1900182 48 0.020
multicellular organismal signaling GO:0035637 34 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.019
stem cell differentiation GO:0048863 93 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
response to hormone GO:0009725 175 0.019
signal transduction by p53 class mediator GO:0072331 72 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
negative regulation of hydrolase activity GO:0051346 182 0.018
detection of stimulus GO:0051606 85 0.018
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
regulation of peptidase activity GO:0052547 180 0.018
cell development GO:0048468 328 0.018
Yeast
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
lipid metabolic process GO:0006629 381 0.018
negative regulation of cell division GO:0051782 31 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
negative regulation of protein catabolic process GO:0042177 59 0.017
mrna metabolic process GO:0016071 175 0.017
histone mrna catabolic process GO:0071044 10 0.017
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.017
epithelial cell differentiation GO:0030855 141 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
cell projection morphogenesis GO:0048858 129 0.017
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
positive regulation of dna metabolic process GO:0051054 73 0.017
regulation of protein targeting GO:1903533 91 0.017
regulation of gtpase activity GO:0043087 180 0.017
response to light stimulus GO:0009416 87 0.017
protein dephosphorylation GO:0006470 81 0.017
cell type specific apoptotic process GO:0097285 125 0.017
proteasomal protein catabolic process GO:0010498 176 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
multicellular organismal aging GO:0010259 3 0.016
organelle assembly GO:0070925 176 0.016
response to hypoxia GO:0001666 96 0.016
gtp catabolic process GO:0006184 237 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.016
phosphatidylinositol metabolic process GO:0046488 53 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
reproductive process GO:0022414 106 0.015
Yeast
regulation of dna methylation GO:0044030 2 0.015
protein methylation GO:0006479 74 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
nervous system development GO:0007399 293 0.015
positive regulation of protein transport GO:0051222 135 0.015
protein acylation GO:0043543 138 0.015
regulation of cell division GO:0051302 116 0.015
protein ubiquitination GO:0016567 314 0.015
cellular response to reactive oxygen species GO:0034614 50 0.015
regulation of mitotic sister chromatid separation GO:0010965 27 0.015
regulation of dna biosynthetic process GO:2000278 18 0.014
action potential GO:0001508 34 0.014
retina homeostasis GO:0001895 42 0.014
cilium morphogenesis GO:0060271 75 0.014
protein deubiquitination GO:0016579 79 0.014
positive regulation of viral process GO:0048524 37 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
Yeast
negative regulation of catalytic activity GO:0043086 335 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
regulation of membrane potential GO:0042391 95 0.013
oocyte maturation GO:0001556 1 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
histone h4 k20 methylation GO:0034770 1 0.013
reproduction GO:0000003 63 0.013
Yeast Mouse Worm
cellular protein catabolic process GO:0044257 261 0.013
positive regulation of response to dna damage stimulus GO:2001022 43 0.013
oogenesis GO:0048477 2 0.013
mitotic g1 dna damage checkpoint GO:0031571 17 0.013
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 9 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
intracellular mrna localization GO:0008298 1 0.013
regulation of cellular component movement GO:0051270 334 0.013
positive regulation of dna replication GO:0045740 35 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
regulation of dna templated transcription elongation GO:0032784 23 0.013
negative regulation of transferase activity GO:0051348 124 0.013
response to alkaloid GO:0043279 20 0.013
adipose tissue development GO:0060612 2 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
regulation of rho protein signal transduction GO:0035023 79 0.013
negative regulation of response to wounding GO:1903035 47 0.012
response to caffeine GO:0031000 3 0.012
positive regulation of cell activation GO:0050867 81 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
positive regulation of leukocyte activation GO:0002696 80 0.012
b cell mediated immunity GO:0019724 10 0.012
lymphocyte proliferation GO:0046651 70 0.012
gene silencing GO:0016458 49 0.012
meiotic cell cycle GO:0051321 13 0.012
Yeast Mouse Worm
nuclear transport GO:0051169 179 0.012
internal protein amino acid acetylation GO:0006475 101 0.012
regulation of immune response GO:0050776 201 0.012
positive regulation of microtubule polymerization or depolymerization GO:0031112 8 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
epithelial cell development GO:0002064 34 0.012
maintenance of dna repeat elements GO:0043570 4 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cytokine production GO:0001816 247 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.012
lipoprotein metabolic process GO:0042157 42 0.012
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.012
gtp metabolic process GO:0046039 239 0.012
histone phosphorylation GO:0016572 16 0.011
regulation of protein transport GO:0051223 213 0.011
histone lysine methylation GO:0034968 50 0.011
cell projection assembly GO:0030031 126 0.011
cellular response to nutrient levels GO:0031669 69 0.011

MRE11A disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.974
hematopoietic system disease DOID:74 100 0.950
bone marrow disease DOID:4961 31 0.890
aplastic anemia DOID:12449 30 0.803
anemia DOID:2355 55 0.803
cancer DOID:162 167 0.690
disease of cellular proliferation DOID:14566 174 0.690
organ system cancer DOID:0050686 164 0.228
central nervous system disease DOID:331 186 0.075
neurodegenerative disease DOID:1289 102 0.075
nervous system disease DOID:863 431 0.075
immune system cancer DOID:0060083 36 0.071
hematologic cancer DOID:2531 36 0.071
thoracic cancer DOID:5093 21 0.061
breast cancer DOID:1612 21 0.029
congenital hypoplastic anemia DOID:1342 26 0.018
fanconi s anemia DOID:13636 16 0.013
disease of mental health DOID:150 70 0.012
cognitive disorder DOID:1561 29 0.012
kidney cancer DOID:263 11 0.012
urinary system cancer DOID:3996 15 0.012