|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
1.000
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
1.000
|
|
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
1.000
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
1.000
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
1.000
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
1.000
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
1.000
|
Fly |
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
1.000
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
1.000
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
1.000
|
|
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
1.000
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.999
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.999
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.999
|
Human |
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.999
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.999
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.998
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.998
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.998
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.998
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.997
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.997
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.996
|
|
|
|
response to prostaglandin e
|
GO:0034695 |
6 |
0.995
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.995
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.995
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.994
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.994
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.994
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.993
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.993
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.993
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.993
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.993
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.992
|
|
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.992
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.992
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.991
|
|
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.990
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.989
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
7 |
0.988
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.986
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.986
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.985
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.984
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.983
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.982
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.982
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.981
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.981
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.981
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.981
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.981
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.980
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.979
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.978
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.977
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.977
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.972
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.970
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
3 |
0.968
|
|
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.968
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.967
|
Mouse |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.967
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.962
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.961
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.957
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.955
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.954
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.953
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.950
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.950
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.949
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.947
|
Mouse |
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.947
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.946
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.945
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.942
|
Mouse |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.936
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.936
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.935
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.932
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.932
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.931
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.930
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.928
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.927
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.920
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.916
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.915
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.909
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.907
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.903
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.902
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.901
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.900
|
Human Rat |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.899
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.897
|
Rat |
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.896
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.895
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.894
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.894
|
Rat |
|
|
tissue migration
|
GO:0090130 |
119 |
0.888
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.887
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.881
|
Human |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.881
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.875
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.874
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.873
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.873
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.870
|
Human Rat |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.863
|
Human Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.858
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.853
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.851
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.848
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.848
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.847
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.843
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.838
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.834
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.833
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.832
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.831
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.828
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.825
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.825
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.822
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.818
|
|
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.818
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.817
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.815
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.813
|
Rat |
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.811
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.808
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.807
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.801
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.797
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.795
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.787
|
Rat |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.787
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.786
|
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.778
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.772
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.772
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.772
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.772
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.769
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.767
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.767
|
Human Rat |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.766
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.766
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.765
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.762
|
|
|
|
system process
|
GO:0003008 |
349 |
0.759
|
Human Rat |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.758
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.746
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.737
|
Rat |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.736
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.732
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.727
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.725
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.718
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.713
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.708
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.708
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.708
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.706
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.700
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.700
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.698
|
Human |
|
|
hair cycle
|
GO:0042633 |
28 |
0.698
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.693
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.687
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.686
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.684
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.680
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.679
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.678
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.675
|
|
|
|
positive regulation of systemic arterial blood pressure
|
GO:0003084 |
2 |
0.673
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.672
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.666
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.660
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.658
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.651
|
|
|
|
craniofacial suture morphogenesis
|
GO:0097094 |
3 |
0.642
|
Rat |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.641
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.639
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.638
|
|
|
|
negative regulation of macrophage cytokine production
|
GO:0010936 |
3 |
0.638
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.631
|
Human |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.630
|
|
|
|
growth plate cartilage development
|
GO:0003417 |
1 |
0.630
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.627
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.615
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.614
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.609
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.607
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.604
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.602
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.597
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.592
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
0.589
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.587
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.584
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.576
|
Human Rat |
|
|
vasculature development
|
GO:0001944 |
181 |
0.574
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.567
|
Human Rat |
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.563
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.556
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.552
|
|
|
|
palate development
|
GO:0060021 |
13 |
0.551
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.551
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.550
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.550
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.547
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.536
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.535
|
|
|
|
venous blood vessel development
|
GO:0060841 |
2 |
0.534
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.523
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.522
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.520
|
Rat |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.517
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.516
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.511
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.511
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.511
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.510
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.510
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.499
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.494
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.494
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.491
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.486
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.486
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.484
|
Rat |
|
|
negative regulation of nitric oxide mediated signal transduction
|
GO:0010751 |
2 |
0.478
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.477
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.476
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.474
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.474
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.470
|
Mouse Rat |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.463
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.454
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.449
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.449
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.448
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.439
|
Human |
|
|
endothelium development
|
GO:0003158 |
33 |
0.438
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.437
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.436
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.434
|
Human Mouse Rat |
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.429
|
|
|
|
endothelial cell cell adhesion
|
GO:0071603 |
1 |
0.428
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.428
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.423
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.419
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.416
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.416
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.411
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.411
|
Human Rat |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.410
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.409
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.407
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.402
|
Mouse |
|
|
response to sterol
|
GO:0036314 |
14 |
0.398
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.395
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.395
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.393
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.390
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.390
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.389
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.387
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.387
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.387
|
Mouse Rat |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.386
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.383
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.382
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.377
|
Mouse |
|
|
smooth muscle tissue development
|
GO:0048745 |
3 |
0.376
|
|
|
|
artery development
|
GO:0060840 |
7 |
0.375
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.373
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.372
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.367
|
|
|
|
positive regulation of hair follicle development
|
GO:0051798 |
3 |
0.365
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.364
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.363
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.362
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.362
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.361
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.361
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.356
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.355
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.353
|
Human Rat |
|
|
regulation of nitric oxide mediated signal transduction
|
GO:0010749 |
2 |
0.351
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.347
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.347
|
Rat |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.345
|
|
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
0.345
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.343
|
Human Rat |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.341
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.339
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.338
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.336
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.335
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.334
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.334
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.333
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.330
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.326
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.326
|
|
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
1 |
0.324
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.323
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.322
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.322
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.321
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.319
|
|
|
|
bronchus development
|
GO:0060433 |
1 |
0.319
|
|
|
|
negative regulation of cell junction assembly
|
GO:1901889 |
5 |
0.319
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.318
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.318
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.318
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.316
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.316
|
Rat |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.315
|
Mouse |
|
|
venous blood vessel morphogenesis
|
GO:0048845 |
1 |
0.315
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.314
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.313
|
|
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
0.311
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.311
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.311
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.311
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.307
|
Mouse Rat |
|
|
organ growth
|
GO:0035265 |
12 |
0.306
|
Human |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.306
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.306
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.305
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.305
|
Mouse Rat |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.300
|
|
|
|
negative regulation of endothelial cell proliferation
|
GO:0001937 |
20 |
0.298
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.296
|
Mouse Rat |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.294
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.294
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.292
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.288
|
Human |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.288
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.287
|
Rat |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.285
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.283
|
Human Rat Fly |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.283
|
|
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.280
|
|
|
|
negative regulation of reproductive process
|
GO:2000242 |
7 |
0.279
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.278
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.278
|
|
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.273
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.271
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.270
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.270
|
|
|
|
negative regulation of plasminogen activation
|
GO:0010757 |
4 |
0.270
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.267
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.266
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.266
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.266
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.262
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.262
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.261
|
|
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.259
|
|
|
|
regulation of macrophage cytokine production
|
GO:0010935 |
4 |
0.258
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.256
|
|
|
|
aging
|
GO:0007568 |
66 |
0.256
|
Rat Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.255
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.255
|
|
|
|
chondrocyte differentiation involved in endochondral bone morphogenesis
|
GO:0003413 |
1 |
0.252
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.250
|
|
|
|
negative regulation of hydrogen peroxide metabolic process
|
GO:0010727 |
3 |
0.250
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.250
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.250
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.250
|
Rat |
|
|
negative regulation of activin receptor signaling pathway
|
GO:0032926 |
6 |
0.244
|
|
|
|
negative regulation of endothelial cell chemotaxis
|
GO:2001027 |
4 |
0.243
|
|
|
|
regulation of fibroblast migration
|
GO:0010762 |
7 |
0.242
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.241
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.240
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.239
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.239
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.235
|
|
|
|
positive regulation of hair cycle
|
GO:0042635 |
3 |
0.233
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.232
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.231
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.228
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.228
|
Human |
|
|
reproductive process
|
GO:0022414 |
106 |
0.228
|
Mouse Rat |
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.227
|
|
|
|
embryonic neurocranium morphogenesis
|
GO:0048702 |
1 |
0.227
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.225
|
|
|
|
atrial septum development
|
GO:0003283 |
8 |
0.225
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.224
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.224
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.223
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.221
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.221
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.220
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.219
|
Worm |
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.218
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.218
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.217
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.216
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.216
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.211
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.210
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.210
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.209
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.209
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.206
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.206
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.206
|
Mouse Rat |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.205
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.204
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.204
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.203
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
9 |
0.203
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.202
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.201
|
|
|
|
artery morphogenesis
|
GO:0048844 |
7 |
0.199
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.197
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.196
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.196
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.196
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.195
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.195
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.194
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.193
|
Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.193
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.193
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.192
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.192
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.191
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.191
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.191
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.190
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.190
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.189
|
Human Rat |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.188
|
|
|
|
positive regulation of receptor binding
|
GO:1900122 |
1 |
0.185
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
9 |
0.181
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.181
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.181
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.179
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.175
|
Mouse Rat |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.175
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.174
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.174
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.174
|
Mouse |
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.173
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.173
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.173
|
Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.172
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.172
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.172
|
Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.170
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.168
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.168
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.167
|
|
|
|
growth
|
GO:0040007 |
202 |
0.167
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.167
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.165
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.163
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.163
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.163
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.163
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.162
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.162
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.161
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.159
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.158
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.157
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.156
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.156
|
Rat Fly |
|
|
negative regulation of adherens junction organization
|
GO:1903392 |
5 |
0.156
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.155
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.154
|
Human |
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.154
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.153
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.153
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.152
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.152
|
|
