Homo sapiens

122 known processes

UIMC1

ubiquitin interaction motif containing 1

(Aliases: RAP80,X2HRIP110)

UIMC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna damage checkpoint GO:0000077 68 0.718
cellular response to dna damage stimulus GO:0006974 379 0.671
dna repair GO:0006281 198 0.566
positive regulation of dna repair GO:0045739 25 0.533
cell cycle checkpoint GO:0000075 117 0.521
dna integrity checkpoint GO:0031570 71 0.466
double strand break repair GO:0006302 101 0.421
regulation of cellular response to stress GO:0080135 244 0.368
positive regulation of response to dna damage stimulus GO:2001022 43 0.329
response to ionizing radiation GO:0010212 65 0.260
positive regulation of dna metabolic process GO:0051054 73 0.256
g2 dna damage checkpoint GO:0031572 26 0.255
response to radiation GO:0009314 151 0.235
response to abiotic stimulus GO:0009628 336 0.233
regulation of dna repair GO:0006282 47 0.230
protein modification by small protein removal GO:0070646 92 0.163
chromatin modification GO:0016568 298 0.130
protein deubiquitination GO:0016579 79 0.112
protein k63 linked deubiquitination GO:0070536 21 0.107
histone modification GO:0016570 251 0.107
regulation of dna metabolic process GO:0051052 153 0.094
chromatin organization GO:0006325 351 0.073
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
mrna metabolic process GO:0016071 175 0.043
regulation of cell cycle GO:0051726 393 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
protein modification by small protein conjugation GO:0032446 342 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
small gtpase mediated signal transduction GO:0007264 78 0.035
regulation of mitotic cell cycle GO:0007346 189 0.033
ras protein signal transduction GO:0007265 73 0.032
positive regulation of catabolic process GO:0009896 310 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.030
cellular macromolecule catabolic process GO:0044265 380 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
covalent chromatin modification GO:0016569 254 0.030
regulation of protein catabolic process GO:0042176 155 0.029
anterior posterior axis specification GO:0009948 2 0.029
cellular response to abiotic stimulus GO:0071214 117 0.029
negative regulation of developmental process GO:0051093 247 0.029
post embryonic development GO:0009791 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
amine metabolic process GO:0009308 44 0.028
response to uv GO:0009411 73 0.027
cytoplasmic transport GO:0016482 379 0.027
protein catabolic process GO:0030163 325 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
regeneration GO:0031099 4 0.026
regulation of proteolysis GO:0030162 293 0.025
mitotic cell cycle process GO:1903047 286 0.025
cellular amino acid metabolic process GO:0006520 116 0.024
negative regulation of cell cycle process GO:0010948 121 0.024
macromolecular complex disassembly GO:0032984 60 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
protein ubiquitination GO:0016567 314 0.024
regulation of protein kinase activity GO:0045859 289 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
proteasomal protein catabolic process GO:0010498 176 0.023
blood vessel morphogenesis GO:0048514 162 0.023
mrna processing GO:0006397 133 0.022
segmentation GO:0035282 4 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
cellular ketone metabolic process GO:0042180 80 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
regulation of cell cycle process GO:0010564 266 0.021
hindbrain development GO:0030902 3 0.021
dephosphorylation GO:0016311 209 0.021
protein maturation GO:0051604 233 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
negative regulation of cell cycle phase transition GO:1901988 89 0.020
purine nucleoside monophosphate catabolic process GO:0009128 158 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
positive regulation of developmental process GO:0051094 314 0.020
sex determination GO:0007530 3 0.019
modification dependent protein catabolic process GO:0019941 209 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
positive regulation of proteolysis GO:0045862 142 0.019
regulation of cell differentiation GO:0045595 393 0.019
mapk cascade GO:0000165 288 0.019
oocyte differentiation GO:0009994 2 0.019
intrinsic apoptotic signaling pathway GO:0097193 127 0.019
response to light stimulus GO:0009416 87 0.019
oocyte maturation GO:0001556 1 0.019
negative regulation of cell death GO:0060548 345 0.019
angiogenesis GO:0001525 147 0.019
determination of adult lifespan GO:0008340 2 0.019
regulation of peptidase activity GO:0052547 180 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
regulation of cell cycle phase transition GO:1901987 126 0.019
neuroblast proliferation GO:0007405 4 0.018
blastoderm segmentation GO:0007350 2 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.018
monocarboxylic acid biosynthetic process GO:0072330 67 0.018
cell division GO:0051301 168 0.018
negative regulation of cell cycle GO:0045786 193 0.018
stem cell division GO:0017145 2 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
cell adhesion GO:0007155 325 0.018
compound eye development GO:0048749 1 0.018
calcium ion homeostasis GO:0055074 122 0.018
divalent inorganic cation homeostasis GO:0072507 136 0.017
single organism cellular localization GO:1902580 332 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
positive regulation of immune response GO:0050778 159 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
protein complex disassembly GO:0043241 52 0.017
cellular response to uv GO:0034644 32 0.017
protein processing GO:0016485 226 0.017
regulation of kinase activity GO:0043549 314 0.017
cation homeostasis GO:0055080 189 0.017
oxidation reduction process GO:0055114 396 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
oogenesis GO:0048477 2 0.016
regulation of protein maturation GO:1903317 150 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
mitotic cell cycle GO:0000278 326 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
oocyte development GO:0048599 1 0.016
sequestering of metal ion GO:0051238 24 0.016
cellular component disassembly GO:0022411 92 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
response to axon injury GO:0048678 1 0.015
negative regulation of protein modification process GO:0031400 200 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
regulation of intracellular transport GO:0032386 195 0.015
regulation of vasculature development GO:1901342 97 0.015
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
cellular response to light stimulus GO:0071482 34 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
cation transport GO:0006812 331 0.015
innate immune response GO:0045087 178 0.015
response to oxygen containing compound GO:1901700 369 0.014
sequestering of calcium ion GO:0051208 17 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
nucleotide catabolic process GO:0009166 408 0.014
regulation of viral process GO:0050792 103 0.014
cellular protein catabolic process GO:0044257 261 0.014
negative regulation of protein maturation GO:1903318 142 0.014
cellular lipid metabolic process GO:0044255 303 0.014
immune response GO:0006955 307 0.014
cellular cation homeostasis GO:0030003 163 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
regulation of angiogenesis GO:0045765 92 0.014
response to organic cyclic compound GO:0014070 204 0.014
small molecule biosynthetic process GO:0044283 157 0.014
positive regulation of transferase activity GO:0051347 227 0.014
cellular response to radiation GO:0071478 65 0.014
actin filament based process GO:0030029 224 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
interspecies interaction between organisms GO:0044419 156 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
regulation of carbohydrate metabolic process GO:0006109 54 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
nucleoside triphosphate metabolic process GO:0009141 422 0.013
metal ion homeostasis GO:0055065 169 0.013
g2 m transition of mitotic cell cycle GO:0000086 41 0.013
negative regulation of proteolysis GO:0045861 132 0.013
histone deubiquitination GO:0016578 16 0.013
cellular amine metabolic process GO:0044106 41 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
double strand break repair via homologous recombination GO:0000724 50 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
positive regulation of cell death GO:0010942 263 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
mating GO:0007618 1 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
protein dephosphorylation GO:0006470 81 0.013
nervous system development GO:0007399 293 0.013
cytokinesis GO:0000910 96 0.013
osteoblast differentiation GO:0001649 92 0.013
chemical homeostasis GO:0048878 306 0.013
cellular divalent inorganic cation homeostasis GO:0072503 128 0.013
myeloid cell differentiation GO:0030099 117 0.013
immune system development GO:0002520 195 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
positive regulation of kinase activity GO:0033674 204 0.013
asymmetric stem cell division GO:0098722 1 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
regulation of protein localization GO:0032880 296 0.012
negative regulation of protein processing GO:0010955 142 0.012
thymus development GO:0048538 3 0.012
regulation of protein complex assembly GO:0043254 147 0.012
blastocyst development GO:0001824 3 0.012
lipid metabolic process GO:0006629 381 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
regulation of transferase activity GO:0051338 355 0.012
response to cytokine GO:0034097 232 0.012
memory GO:0007613 3 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
tissue regeneration GO:0042246 3 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
somitogenesis GO:0001756 2 0.012
regulation of response to external stimulus GO:0032101 222 0.012
intracellular protein transport GO:0006886 270 0.012
multicellular organismal aging GO:0010259 3 0.012
maintenance of location GO:0051235 112 0.012
response to fungus GO:0009620 4 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
regulation of immune response GO:0050776 201 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of protein transport GO:0051223 213 0.012
cell fate determination GO:0001709 3 0.012
cellular component morphogenesis GO:0032989 314 0.012
divalent metal ion transport GO:0070838 152 0.012
cellular chemical homeostasis GO:0055082 180 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
female gamete generation GO:0007292 2 0.011
male meiosis GO:0007140 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
dna replication independent nucleosome assembly GO:0006336 27 0.011
negative regulation of transferase activity GO:0051348 124 0.011
trabecula morphogenesis GO:0061383 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
apoptotic signaling pathway GO:0097190 268 0.011
metencephalon development GO:0022037 2 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
adult locomotory behavior GO:0008344 1 0.011
response to lipid GO:0033993 206 0.011
negative regulation of immune system process GO:0002683 136 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
locomotory behavior GO:0007626 1 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
regulation of growth GO:0040008 165 0.011
regulation of cell adhesion GO:0030155 166 0.011
neuromuscular junction development GO:0007528 3 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
glycoprotein metabolic process GO:0009100 110 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
response to wounding GO:0009611 168 0.011
regulation of protein processing GO:0070613 150 0.011
cell growth GO:0016049 160 0.011
motor neuron axon guidance GO:0008045 2 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
organelle assembly GO:0070925 176 0.011
regulation of multi organism process GO:0043900 157 0.011
cardiovascular system development GO:0072358 262 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
response to oxidative stress GO:0006979 121 0.011
protein localization to organelle GO:0033365 280 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
organophosphate catabolic process GO:0046434 430 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
myosin filament organization GO:0031033 2 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
cell cycle phase transition GO:0044770 173 0.010
metal ion transport GO:0030001 272 0.010
organic acid biosynthetic process GO:0016053 97 0.010
cell morphogenesis GO:0000902 296 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
cytokine production GO:0001816 247 0.010
biological adhesion GO:0022610 331 0.010
neuron fate commitment GO:0048663 2 0.010
monocarboxylic acid metabolic process GO:0032787 185 0.010

UIMC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.046
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
eye and adnexa disease DOID:1492 150 0.015
musculoskeletal system disease DOID:17 223 0.012
retinal disease DOID:5679 118 0.011
eye disease DOID:5614 149 0.011
organ system cancer DOID:0050686 164 0.011
breast cancer DOID:1612 21 0.011
thoracic cancer DOID:5093 21 0.011
hematopoietic system disease DOID:74 100 0.010
central nervous system disease DOID:331 186 0.010