|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
1.000
|
Fly |
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
1.000
|
Human |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
1.000
|
Human |
|
|
potassium ion transport
|
GO:0006813 |
62 |
1.000
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
1.000
|
Yeast Fly |
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
1.000
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
1.000
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
1.000
|
Fly |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
1.000
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
Yeast Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
1.000
|
Zebrafish Worm |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
1.000
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
1.000
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
1.000
|
Human |
|
|
membrane depolarization during action potential
|
GO:0086010 |
10 |
1.000
|
Human |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
1.000
|
Human |
|
|
regulation of peptidyl serine dephosphorylation
|
GO:1902308 |
2 |
1.000
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
1.000
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
1.000
|
Fly |
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
1.000
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
1.000
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
1.000
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
1.000
|
Yeast |
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
1.000
|
Human |
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
1.000
|
Human |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
1.000
|
Human |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
1.000
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
1.000
|
Fly |
|
|
steroid catabolic process
|
GO:0006706 |
10 |
1.000
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
1.000
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
1.000
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
1.000
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
1.000
|
Worm Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
1.000
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
1.000
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
1.000
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
1.000
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
1.000
|
Human Yeast Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
1.000
|
|
|
|
action potential
|
GO:0001508 |
34 |
1.000
|
Human |
|
|
tor signaling
|
GO:0031929 |
39 |
1.000
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
1.000
|
Human |
|
|
membrane repolarization
|
GO:0086009 |
23 |
1.000
|
Human |
|
|
specification of axis polarity
|
GO:0065001 |
1 |
0.999
|
Worm |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.999
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.999
|
Worm |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.999
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.999
|
Human |
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.999
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.999
|
Yeast |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.999
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.999
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.999
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.999
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.999
|
Yeast |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.999
|
Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.999
|
Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.999
|
Human |
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.999
|
Worm |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.999
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.999
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.999
|
Human Yeast |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.998
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.998
|
Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.998
|
Fly |
|
|
peptidyl serine dephosphorylation
|
GO:0070262 |
2 |
0.998
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.998
|
Worm |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.998
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.998
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.998
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.998
|
Worm |
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.998
|
Yeast |
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.997
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.997
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.997
|
Human |
|
|
negative regulation of peptidyl serine dephosphorylation
|
GO:1902309 |
1 |
0.997
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.997
|
Fly |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.997
|
Human |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.997
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.996
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.996
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.996
|
Fly |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.996
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.996
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.996
|
Zebrafish Worm |
|
|
glucocorticoid catabolic process
|
GO:0006713 |
1 |
0.996
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.995
|
Fly |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.995
|
Human |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.995
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.995
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.995
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.995
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.994
|
Worm |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.994
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.994
|
Human |
|
|
glucocorticoid receptor signaling pathway
|
GO:0042921 |
5 |
0.994
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.994
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.994
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.993
|
Human |
|
|
protein processing
|
GO:0016485 |
226 |
0.993
|
Human |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.993
|
Worm Fly |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.993
|
Worm |
|
|
organelle fission
|
GO:0048285 |
149 |
0.993
|
Yeast Worm |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.992
|
Human Yeast |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.992
|
Human Yeast |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.992
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.992
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.992
|
Human |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.991
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.991
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.991
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.991
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.990
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.990
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.990
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.990
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.989
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.989
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.989
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.988
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.988
|
Worm |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.988
|
Human |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.987
|
Worm |
|
|
nervous system development
|
GO:0007399 |
293 |
0.987
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.987
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.986
|
Human |
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.985
|
Human |
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.985
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.984
|
Worm Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.982
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.982
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.981
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.980
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.980
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.978
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.977
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.976
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.976
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.976
|
Human |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.974
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.973
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.971
|
Yeast Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.971
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.971
|
Yeast Worm |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.970
|
Worm Fly |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.969
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.969
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.967
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.966
|
Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.966
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.963
|
Human |
|
|
nuclear division
|
GO:0000280 |
128 |
0.962
|
Yeast Worm |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.962
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.962
|
Worm |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.961
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.959
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.958
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.958
|
Human |
|
|
brain development
|
GO:0007420 |
97 |
0.957
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.957
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.955
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.953
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.953
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.952
|
Yeast Worm |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.946
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.945
|
Human |
|
|
fertilization
|
GO:0009566 |
12 |
0.944
|
Worm |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.940
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.939
|
Human |
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.934
|
Yeast |
|
|
nuclear migration
|
GO:0007097 |
1 |
0.933
|
Worm |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.933
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.932
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.932
|
Yeast |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.931
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.930
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.930
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.928
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.927
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.927
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.927
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.926
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.925
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.920
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.919
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.919
|
Yeast |
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.916
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.916
|
Worm Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.912
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.911
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.909
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.906
|
Yeast Worm Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.905
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.904
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.903
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.902
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.902
|
Yeast |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.901
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.900
|
Human Yeast |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.900
|
Yeast |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.896
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.895
|
Yeast |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.894
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.893
|
Human |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.890
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.890
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.890
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.889
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.889
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.889
|
Yeast |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
12 |
0.887
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.886
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.883
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.882
|
Worm |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.881
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.878
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.871
|
Yeast Worm |
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.871
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.866
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.866
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.866
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.866
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.864
|
Fly |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.862
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.862
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.860
|
Human |
|
|
aging
|
GO:0007568 |
66 |
0.853
|
Worm |
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.852
|
Worm |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.849
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.847
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.844
|
Yeast |
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.843
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.840
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.838
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.836
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.835
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.835
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.831
|
Fly |
|
|
autophagy
|
GO:0006914 |
88 |
0.831
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.828
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.827
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.827
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.826
|
Yeast |
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.823
|
Human |
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.821
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.819
|
Human |
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.819
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.813
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.811
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.804
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.800
|
Fly |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.795
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.794
|
|
|
|
aggresome assembly
|
GO:0070842 |
4 |
0.789
|
Yeast |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.788
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.786
|
Worm Fly |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.783
|
Human |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.775
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.774
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.762
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.759
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.757
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.756
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.748
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.745
|
Fly |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.739
|
Human |
|
|
neuron development
|
GO:0048666 |
113 |
0.733
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.731
|
Yeast |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.728
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.728
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.722
|
Yeast |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.721
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.714
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.709
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.702
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.696
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.686
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.685
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.674
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.672
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.666
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.663
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.659
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.657
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.653
|
Yeast Worm Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.650
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.649
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.649
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.633
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.628
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.627
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.622
|
Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.621
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.620
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.619
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.607
|
Worm |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.606
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.602
|
Yeast |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.595
|
Worm Fly |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.592
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.591
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.587
|
Fly |
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.584
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.580
|
Worm Fly |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.578
|
Yeast |
|
|
midbrain development
|
GO:0030901 |
45 |
0.576
|
Human |
|
|
regionalization
|
GO:0003002 |
29 |
0.566
|
Worm |
|
|
cell maturation
|
GO:0048469 |
11 |
0.566
|
Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.566
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.563
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.562
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.553
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.547
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.546
|
Fly |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.541
|
Yeast |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.540
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.535
|
Yeast |
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.518
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.514
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.510
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.509
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.506
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.504
|
Yeast |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.501
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.499
|
Yeast |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.497
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.494
|
Worm |
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.492
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.490
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.488
|
|
|
|
inclusion body assembly
|
GO:0070841 |
17 |
0.486
|
Yeast |
|
|
system process
|
GO:0003008 |
349 |
0.483
|
Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.481
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.479
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.477
|
Yeast Worm Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.477
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.475
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.473
|
Yeast |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.472
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.468
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.463
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.459
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.454
|
Yeast |
|
|
epithelium development
|
GO:0060429 |
227 |
0.446
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.442
|
Worm |
|
|
centrosome organization
|
GO:0051297 |
58 |
0.442
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.439
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.438
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.437
|
Yeast Worm |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.437
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.433
|
Yeast |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.420
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.418
|
Human Yeast |
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
23 |
0.414
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.409
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.407
|
Yeast |
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.407
|
Yeast |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.401
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.395
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.395
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.393
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.385
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.385
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.384
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.383
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.374
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.368
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.367
|
Yeast |
|
|
head development
|
GO:0060322 |
108 |
0.359
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.347
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.346
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.343
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.335
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.332
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.330
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.328
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.326
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.325
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.325
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.324
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.324
|
Zebrafish |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.323
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.323
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
17 |
0.318
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.317
|
Worm Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.317
|
Human |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.310
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.308
|
Yeast |
|
|
kidney development
|
GO:0001822 |
53 |
0.301
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.297
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.297
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.292
|
Yeast |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.288
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.285
|
Yeast Worm Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.284
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.282
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.276
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.272
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.268
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.268
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.257
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
18 |
0.256
|
Yeast |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.255
|
|
|
|
peroxisome degradation
|
GO:0030242 |
1 |
0.249
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.248
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.248
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.241
|
Fly |
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.238
|
Yeast |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.237
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.234
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.229
|
Human |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.226
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.223
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.222
|
Worm Fly |
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.221
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.220
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.218
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.215
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.213
|
Yeast |
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.210
|
Worm |
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.210
|
Yeast |
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.210
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.208
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.208
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.207
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.205
|
Yeast |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.204
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.203
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.203
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.197
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.191
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.191
|
|
|
|
regulation of filopodium assembly
|
GO:0051489 |
13 |
0.190
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.189
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.188
|
Yeast |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.187
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.179
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.178
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.178
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.177
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.171
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.170
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.170
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.168
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.168
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.167
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.165
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.162
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.162
|
Yeast |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.160
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.159
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.157
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.155
|
|
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.154
|
Yeast |
|
|
response to starvation
|
GO:0042594 |
59 |
0.153
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.151
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.151
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
12 |
0.151
|
Worm |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.147
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.147
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.146
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.145
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.144
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.142
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.141
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.139
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.139
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.138
|
Yeast Worm Fly |
|
|
vasculature development
|
GO:0001944 |
181 |
0.131
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.128
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.127
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.126
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.124
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.123
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.119
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.119
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.118
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
15 |
0.116
|
Fly |
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.114
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.114
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.112
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.111
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.110
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.110
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.109
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.109
|
|
|
|
germ cell development
|
GO:0007281 |
8 |
0.108
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.107
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.107
|
Yeast |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.103
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.102
|
Yeast |
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.102
|
Yeast |
|
|
response to parathyroid hormone
|
GO:0071107 |
3 |
0.102
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.098
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.098
|
|
