|
|
neuron differentiation
|
GO:0030182 |
138 |
0.999
|
Human Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.998
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.998
|
Human Fly |
|
|
growth
|
GO:0040007 |
202 |
0.997
|
Fly |
|
|
regulation of peptidyl serine dephosphorylation
|
GO:1902308 |
2 |
0.996
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.995
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.994
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.994
|
Fly |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.990
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.990
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.989
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.988
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.988
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.988
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.985
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.981
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.980
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.977
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.971
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.971
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.969
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.969
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.968
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.968
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.967
|
Fly |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.966
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.957
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.956
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.956
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.954
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.950
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.948
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.945
|
Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.942
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.939
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.938
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.937
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.931
|
Fly |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.930
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.926
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.923
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.922
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.921
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.916
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.914
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.908
|
Fly |
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.907
|
Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.906
|
Human |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.902
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.902
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.901
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.898
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.896
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.896
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.895
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.889
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.887
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.882
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.881
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.881
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.880
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.879
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.879
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.878
|
Human |
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.878
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.866
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.859
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.855
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.851
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.851
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.846
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.846
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.844
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.841
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.841
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.839
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.837
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.834
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.833
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.832
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.831
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.824
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.822
|
Human Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.820
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.818
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.817
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.804
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.800
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.797
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.796
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.789
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.786
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.781
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.780
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.776
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.774
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.763
|
Fly |
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.760
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.758
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.752
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.743
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.739
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.734
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.734
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.734
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.727
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.725
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.725
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.722
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.713
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.708
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.708
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.704
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.703
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.700
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.698
|
Fly |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.697
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.691
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.690
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.674
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.671
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.667
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.663
|
Fly |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.659
|
Fly |
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.659
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.656
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.656
|
Fly |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.655
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.652
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.646
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.641
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.639
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.627
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.624
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.621
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.618
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.615
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.611
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.610
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.609
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.607
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.596
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.595
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.588
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.586
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.585
|
Human Mouse Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.581
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.579
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.579
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.577
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.576
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.574
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.574
|
|
|
|
negative regulation of peptidyl serine dephosphorylation
|
GO:1902309 |
1 |
0.570
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.569
|
Fly |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.569
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.568
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.565
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.564
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.559
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.558
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.558
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.558
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.555
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.555
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.554
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.548
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.547
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.546
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.537
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.536
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.533
|
Human |
|
|
glucocorticoid catabolic process
|
GO:0006713 |
1 |
0.529
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.527
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.525
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.525
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.522
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.520
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.520
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.516
|
Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.514
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.511
|
Mouse |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.508
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.507
|
Fly |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.505
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.504
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.497
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.497
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.497
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.490
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.489
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.489
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.484
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.481
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.477
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.472
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.471
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.469
|
|
|
|
peptidyl serine dephosphorylation
|
GO:0070262 |
2 |
0.469
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.465
|
Fly |
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.463
|
Human |
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.462
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.462
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.462
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.458
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.457
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.455
|
|
|
|
head development
|
GO:0060322 |
108 |
0.453
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.452
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.449
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
7 |
0.444
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.442
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.438
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.436
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.431
|
Human |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.428
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.420
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.419
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.419
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.416
|
Human Mouse Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.416
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.413
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.410
|
|
|
|
steroid catabolic process
|
GO:0006706 |
10 |
0.408
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.407
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.403
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.399
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.398
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.398
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.397
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.397
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.393
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.392
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.385
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.384
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.378
|
Fly |
|
|
erk5 cascade
|
GO:0070375 |
1 |
0.374
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.371
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.367
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.367
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.366
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.355
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.352
|
Human |
|
|
specification of axis polarity
|
GO:0065001 |
1 |
0.349
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.349
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.344
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.344
|
Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.344
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.340
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.339
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.335
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.334
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.333
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.333
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.330
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.327
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.320
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.319
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.318
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.309
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.308
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.306
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.303
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.302
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.299
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.298
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.298
|
Fly |
|
|
cellular senescence
|
GO:0090398 |
34 |
0.298
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.297
|
|
|
|
regulation of cardiac muscle contraction by calcium ion signaling
|
GO:0010882 |
3 |
0.296
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.288
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.288
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.288
|
Fly |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.283
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.281
|
Fly |
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.277
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.277
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.275
|
Human |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.275
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.270
|
Fly |
|
|
single organism behavior
|
GO:0044708 |
28 |
0.268
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.267
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.266
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.263
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.263
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.262
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.257
|
Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.256
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.255
|
Fly |
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.253
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.253
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.250
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.250
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.250
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.249
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.246
|
Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.246
|
Fly |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.245
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.244
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.243
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.243
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.242
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.241
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.240
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.239
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.238
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.237
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.237
|
|
|
|
aggresome assembly
|
GO:0070842 |
4 |
0.236
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.234
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.232
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.230
|
Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.230
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.229
|
|
|
|
negative regulation of cell migration involved in sprouting angiogenesis
|
GO:0090051 |
6 |
0.228
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.227
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.225
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.224
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.222
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.222
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.220
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.219
|
Human |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.218
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.218
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.217
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.217
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.216
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.215
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.215
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.214
|
Fly |
|
|
signal release
|
GO:0023061 |
70 |
0.213
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.213
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.211
|
Human |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.209
|
Fly |
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.208
|
Fly |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.205
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.204
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.203
|
Human |
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.201
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.200
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.199
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.199
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.197
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.192
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.192
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.191
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.190
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.189
|
|
|
|
pigment granule organization
|
GO:0048753 |
7 |
0.186
|
|
|
|
response to parathyroid hormone
|
GO:0071107 |
3 |
0.185
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.185
|
Fly |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.183
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.181
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.179
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.179
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.178
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.177
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.176
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.174
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.173
|
Fly |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.172
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.172
|
Human |
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.172
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.172
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.171
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.171
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.170
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.170
|
Fly |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.170
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.169
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.169
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.169
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.168
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.168
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.166
|
|
|
|
fatty acid catabolic process
|
GO:0009062 |
29 |
0.166
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.164
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.164
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.163
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.163
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.163
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.162
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.162
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.161
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.161
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.160
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.159
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.158
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.157
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.157
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.156
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.154
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.154
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.154
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.153
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.152
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.152
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.152
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.151
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.150
|
Fly |
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.149
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.147
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.147
|
Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.147
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.146
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
7 |
0.146
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.145
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.143
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.143
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.142
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.141
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.139
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.139
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.139
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.139
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.139
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.139
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.139
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.139
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.138
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.138
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.137
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.136
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.135
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.134
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.134
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.133
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.133
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.132
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.132
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.131
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.130
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.129
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.129
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.128
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.128
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.128
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.126
|
|
|
|
aging
|
GO:0007568 |
66 |
0.126
|
Fly |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.125
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.123
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.123
|
Fly |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.121
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.119
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.119
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.119
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.118
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.118
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.117
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.117
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.116
|
Fly |
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.114
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.114
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.114
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.114
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.112
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.112
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.111
|
|
|
|
negative regulation of response to extracellular stimulus
|
GO:0032105 |
5 |
0.111
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
5 |
0.111
|
|
|
|
negative regulation of exit from mitosis
|
GO:0001100 |
1 |
0.110
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.110
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.110
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.109
|
Fly |
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
0.108
|
Human |
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
9 |
0.108
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.108
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.108
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.107
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.107
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.106
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.106
|
Fly |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.104
|
Fly |
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.104
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.102
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.099
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.099
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.098
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.097
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.097
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.097
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.096
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.096
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.096
|
Fly |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.095
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.094
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
9 |
0.093
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.093
|
|
|
|
positive regulation of protein sumoylation
|
GO:0033235 |
7 |
0.093
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.092
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.092
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.091
|
|
