Homo sapiens

75 known processes

AGER

advanced glycosylation end product-specific receptor

(Aliases: MGC22357,RAGE)

AGER biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neuronal synaptic plasticity GO:0048168 1 0.573
protein heterotetramerization GO:0051290 3 0.326
rho protein signal transduction GO:0007266 26 0.313
leukocyte migration involved in inflammatory response GO:0002523 2 0.287
positive regulation of cell motility GO:2000147 177 0.262
Rat
memory GO:0007613 3 0.250
small gtpase mediated signal transduction GO:0007264 78 0.240
positive regulation of immune system process GO:0002684 283 0.224
ras protein signal transduction GO:0007265 73 0.214
regulation of cell motility GO:2000145 299 0.208
Rat
positive regulation of ras gtpase activity GO:0032320 117 0.207
guanosine containing compound catabolic process GO:1901069 239 0.206
regulation of cellular component movement GO:0051270 334 0.204
Rat
regulation of cell differentiation GO:0045595 393 0.197
Rat
regulation of chemotaxis GO:0050920 74 0.187
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.183
endothelial cell migration GO:0043542 86 0.179
Rat
nucleoside catabolic process GO:0009164 408 0.178
ribonucleoside catabolic process GO:0042454 406 0.178
nucleoside phosphate catabolic process GO:1901292 412 0.175
positive regulation of developmental process GO:0051094 314 0.173
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.173
regulation of purine nucleotide metabolic process GO:1900542 264 0.173
regulation of gtp catabolic process GO:0033124 180 0.173
organophosphate catabolic process GO:0046434 430 0.170
ribonucleotide catabolic process GO:0009261 405 0.168
guanosine containing compound metabolic process GO:1901068 244 0.168
cell cell signaling GO:0007267 155 0.165
nucleotide catabolic process GO:0009166 408 0.161
gtp catabolic process GO:0006184 237 0.158
positive regulation of gtpase activity GO:0043547 166 0.156
immune response GO:0006955 307 0.156
positive regulation of nucleotide catabolic process GO:0030813 185 0.155
gtp metabolic process GO:0046039 239 0.154
defense response to fungus GO:0050832 4 0.152
system process GO:0003008 349 0.151
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.150
regulation of purine nucleotide catabolic process GO:0033121 205 0.149
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.149
activation of innate immune response GO:0002218 55 0.149
nucleoside triphosphate metabolic process GO:0009141 422 0.143
innate immune response GO:0045087 178 0.138
regulation of small gtpase mediated signal transduction GO:0051056 156 0.136
regulation of nucleotide catabolic process GO:0030811 205 0.136
regulation of nucleotide metabolic process GO:0006140 269 0.136
positive regulation of nucleotide metabolic process GO:0045981 230 0.135
purine nucleotide catabolic process GO:0006195 405 0.135
regulation of cell development GO:0060284 161 0.134
Rat
purine containing compound catabolic process GO:0072523 411 0.134
response to bacterium GO:0009617 144 0.132
regulation of peptidase activity GO:0052547 180 0.132
nucleoside triphosphate catabolic process GO:0009143 394 0.131
pattern recognition receptor signaling pathway GO:0002221 48 0.130
purine nucleoside triphosphate metabolic process GO:0009144 412 0.130
purine nucleoside catabolic process GO:0006152 398 0.130
response to oxygen containing compound GO:1901700 369 0.127
Rat
defense response GO:0006952 315 0.126
Mouse Rat
purine nucleoside triphosphate catabolic process GO:0009146 392 0.124
cellular response to xenobiotic stimulus GO:0071466 29 0.123
glycosyl compound catabolic process GO:1901658 413 0.123
positive regulation of gtp catabolic process GO:0033126 166 0.123
response to xenobiotic stimulus GO:0009410 30 0.121
positive regulation of cellular component movement GO:0051272 181 0.120
Rat
purine ribonucleotide catabolic process GO:0009154 404 0.119
protein maturation GO:0051604 233 0.117
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.115
membrane organization GO:0061024 292 0.113
Mouse Rat
response to wounding GO:0009611 168 0.110
Mouse Rat
activation of immune response GO:0002253 114 0.108
cation transmembrane transport GO:0098655 238 0.108
Rat
purine ribonucleoside catabolic process GO:0046130 398 0.108
regulation of locomotion GO:0040012 329 0.105
Mouse Rat
positive regulation of cell migration GO:0030335 172 0.105
Rat
positive regulation of nucleoside metabolic process GO:0045979 186 0.105
purine ribonucleoside metabolic process GO:0046128 437 0.103
response to fungus GO:0009620 4 0.102
positive regulation of cellular catabolic process GO:0031331 284 0.101
Rat
vesicle mediated transport GO:0016192 371 0.099
Rat
positive regulation of hydrolase activity GO:0051345 331 0.099
regulation of cellular component biogenesis GO:0044087 281 0.097
cation transport GO:0006812 331 0.096
Rat
neurological system process GO:0050877 163 0.096
regulation of gtpase activity GO:0043087 180 0.096
regulation of ras gtpase activity GO:0032318 128 0.096
defense response to bacterium GO:0042742 63 0.095
regulation of response to wounding GO:1903034 101 0.093
Mouse Rat
positive regulation of cell differentiation GO:0045597 211 0.092
Rat
positive regulation of leukocyte chemotaxis GO:0002690 38 0.092
regulation of anatomical structure morphogenesis GO:0022603 286 0.092
Rat
chemical homeostasis GO:0048878 306 0.091
Rat
ribonucleoside triphosphate catabolic process GO:0009203 391 0.090
regulation of immune response GO:0050776 201 0.088
biological adhesion GO:0022610 331 0.086
Rat
regulation of leukocyte migration GO:0002685 63 0.086
positive regulation of cell development GO:0010720 92 0.084
Rat
response to lipid GO:0033993 206 0.083
Rat
leukocyte aggregation GO:0070486 8 0.083
regulation of leukocyte chemotaxis GO:0002688 46 0.083
protein processing GO:0016485 226 0.082
cellular amino acid metabolic process GO:0006520 116 0.081
mapk cascade GO:0000165 288 0.080
Mouse
regulation of rho protein signal transduction GO:0035023 79 0.080
regulation of behavior GO:0050795 82 0.080
Mouse
positive regulation of cellular component organization GO:0051130 376 0.079
Rat
synaptic transmission GO:0007268 61 0.079
cell adhesion GO:0007155 325 0.078
Rat
metal ion transport GO:0030001 272 0.078
Rat
positive regulation of protein phosphorylation GO:0001934 313 0.078
Mouse Rat
regulation of nucleoside metabolic process GO:0009118 209 0.077
ion transmembrane transport GO:0034220 338 0.076
Rat
vesicle organization GO:0016050 62 0.074
apoptotic signaling pathway GO:0097190 268 0.074
regulation of cell morphogenesis GO:0022604 153 0.074
Rat
i kappab kinase nf kappab signaling GO:0007249 166 0.073
positive regulation of catabolic process GO:0009896 310 0.073
Rat
actin filament based process GO:0030029 224 0.072
positive regulation of leukocyte migration GO:0002687 46 0.072
regulation of cell adhesion GO:0030155 166 0.071
Rat
toll like receptor 4 signaling pathway GO:0034142 12 0.070
regulation of apoptotic signaling pathway GO:2001233 175 0.070
cell chemotaxis GO:0060326 112 0.069
nervous system development GO:0007399 293 0.069
regulation of cell migration GO:0030334 289 0.069
Rat
membrane raft assembly GO:0001765 7 0.068
single organism cellular localization GO:1902580 332 0.066
Mouse
immune response regulating signaling pathway GO:0002764 97 0.066
immune response activating signal transduction GO:0002757 90 0.065
cell matrix adhesion GO:0007160 85 0.064
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.064
positive regulation of phosphorylation GO:0042327 394 0.064
Mouse Rat
positive regulation of behavior GO:0048520 60 0.064
Mouse
response to abiotic stimulus GO:0009628 336 0.064
Mouse Rat
positive regulation of chemotaxis GO:0050921 57 0.064
Mouse
positive regulation of programmed cell death GO:0043068 249 0.063
Rat
xenobiotic metabolic process GO:0006805 28 0.063
cell substrate adhesion GO:0031589 132 0.063
epithelium migration GO:0090132 119 0.062
Rat
regulation of rho gtpase activity GO:0032319 66 0.062
cell development GO:0048468 328 0.062
epithelial cell migration GO:0010631 119 0.062
Rat
ameboidal type cell migration GO:0001667 135 0.062
Rat
single organism membrane organization GO:0044802 268 0.062
Mouse
response to other organism GO:0051707 261 0.062
protein oligomerization GO:0051259 173 0.061
regulation of mapk cascade GO:0043408 262 0.061
Mouse
regulation of endopeptidase activity GO:0052548 170 0.061
cellular ketone metabolic process GO:0042180 80 0.060
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.060
positive regulation of cell death GO:0010942 263 0.060
Rat
regulation of cellular amine metabolic process GO:0033238 11 0.060
regulation of transferase activity GO:0051338 355 0.059
Mouse
monocyte chemotaxis GO:0002548 20 0.059
positive regulation of immune response GO:0050778 159 0.059
enzyme linked receptor protein signaling pathway GO:0007167 303 0.059
regulation of response to external stimulus GO:0032101 222 0.059
Mouse Rat
response to molecule of bacterial origin GO:0002237 82 0.058
post embryonic development GO:0009791 2 0.058
positive regulation of organelle organization GO:0010638 195 0.057
positive regulation of cellular component biogenesis GO:0044089 158 0.056
calcium ion transport GO:0006816 147 0.055
regulation of cellular ketone metabolic process GO:0010565 50 0.055
signal transduction by phosphorylation GO:0023014 297 0.055
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 70 0.054
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
endomembrane system organization GO:0010256 196 0.054
regulation of cytoskeleton organization GO:0051493 177 0.054
positive regulation of innate immune response GO:0045089 79 0.054
positive regulation of rac gtpase activity GO:0032855 31 0.053
positive regulation of ion transport GO:0043270 87 0.053
Rat
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.052
positive regulation of cell adhesion GO:0045785 84 0.052
regulation of ion transmembrane transport GO:0034765 132 0.052
Rat
behavior GO:0007610 112 0.052
Mouse
regulation of innate immune response GO:0045088 97 0.052
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.051
actin filament organization GO:0007015 128 0.051
amine metabolic process GO:0009308 44 0.050
secretion by cell GO:0032940 226 0.050
positive regulation of apoptotic process GO:0043065 246 0.049
Rat
positive regulation of rho gtpase activity GO:0032321 56 0.049
regulation of calcium ion transport GO:0051924 79 0.049
regulation of defense response GO:0031347 154 0.048
Mouse Rat
positive regulation of locomotion GO:0040017 186 0.047
Mouse Rat
negative regulation of protein metabolic process GO:0051248 391 0.047
Rat
regulation of adherens junction organization GO:1903391 21 0.047
regulation of ion transport GO:0043269 189 0.047
Rat
response to lipopolysaccharide GO:0032496 70 0.047
plasma membrane organization GO:0007009 115 0.046
regulation of proteolysis GO:0030162 293 0.046
response to external biotic stimulus GO:0043207 261 0.045
regulation of actin filament based process GO:0032970 141 0.045
regulation of cell substrate junction assembly GO:0090109 20 0.045
response to nitrogen compound GO:1901698 184 0.045
protein localization to membrane GO:0072657 160 0.045
Mouse
positive regulation of defense response GO:0031349 87 0.045
Rat
positive regulation of proteolysis GO:0045862 142 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
cellular response to oxygen containing compound GO:1901701 276 0.044
Rat
actin cytoskeleton organization GO:0030036 207 0.044
regulation of ras protein signal transduction GO:0046578 155 0.044
defense response to other organism GO:0098542 129 0.043
single organismal cell cell adhesion GO:0016337 148 0.043
single organism cell adhesion GO:0098602 179 0.043
tissue migration GO:0090130 119 0.043
Rat
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
neutrophil aggregation GO:0070488 2 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.041
Rat
cellular cation homeostasis GO:0030003 163 0.040
locomotory behavior GO:0007626 1 0.040
positive regulation of cytoskeleton organization GO:0051495 83 0.039
regulation of actin cytoskeleton organization GO:0032956 116 0.039
cardiovascular system development GO:0072358 262 0.039
stress fiber assembly GO:0043149 40 0.038
focal adhesion assembly GO:0048041 30 0.038
positive regulation of response to external stimulus GO:0032103 88 0.038
Mouse Rat
positive regulation of mapk cascade GO:0043410 190 0.038
Mouse
granulocyte migration GO:0097530 40 0.037
membrane biogenesis GO:0044091 13 0.037
g protein coupled receptor signaling pathway GO:0007186 207 0.037
determination of adult lifespan GO:0008340 2 0.037
cellular amine metabolic process GO:0044106 41 0.037
chemotaxis GO:0006935 157 0.036
Mouse
positive regulation of focal adhesion assembly GO:0051894 11 0.036
divalent inorganic cation homeostasis GO:0072507 136 0.036
Rat
leukocyte migration GO:0050900 107 0.036
calcium ion transmembrane transport GO:0070588 76 0.036
positive regulation of monocyte chemotaxis GO:0090026 10 0.036
multicellular organismal aging GO:0010259 3 0.035
protein localization to plasma membrane GO:0072659 93 0.035
regulation of inflammatory response GO:0050727 46 0.035
Mouse Rat
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
Rat
cell junction assembly GO:0034329 67 0.035
regulation of focal adhesion assembly GO:0051893 20 0.034
muscle system process GO:0003012 81 0.034
cellular component morphogenesis GO:0032989 314 0.034
Rat
response to cytokine GO:0034097 232 0.033
toll like receptor signaling pathway GO:0002224 25 0.033
activation of protein kinase activity GO:0032147 90 0.033
cytokine production GO:0001816 247 0.033
regulation of protein serine threonine kinase activity GO:0071900 179 0.033
Mouse
taxis GO:0042330 157 0.033
Mouse
positive regulation of cell substrate adhesion GO:0010811 37 0.033
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
cell projection organization GO:0030030 252 0.032
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.032
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.032
muscle contraction GO:0006936 73 0.032
cellular response to endogenous stimulus GO:0071495 336 0.032
leukocyte cell cell adhesion GO:0007159 37 0.031
positive regulation of secretion GO:0051047 116 0.031
central nervous system development GO:0007417 123 0.031
Rat
autophagy GO:0006914 88 0.031
Rat
membrane raft organization GO:0031579 10 0.031
positive regulation of protein kinase activity GO:0045860 190 0.031
Mouse
regulation of granulocyte chemotaxis GO:0071622 16 0.031
response to biotic stimulus GO:0009607 276 0.031
cell morphogenesis GO:0000902 296 0.031
Rat
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.030
regulation of cell substrate adhesion GO:0010810 68 0.030
regulation of cysteine type endopeptidase activity GO:2000116 127 0.030
regulation of cell junction assembly GO:1901888 29 0.030
regulation of actin filament bundle assembly GO:0032231 36 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.030
regulation of protein kinase activity GO:0045859 289 0.030
Mouse
lipid metabolic process GO:0006629 381 0.029
neuromuscular junction development GO:0007528 3 0.029
membrane budding GO:0006900 28 0.029
purine nucleotide biosynthetic process GO:0006164 84 0.029
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
zymogen activation GO:0031638 70 0.029
regulation of cell matrix adhesion GO:0001952 42 0.029
positive regulation of granulocyte chemotaxis GO:0071624 9 0.029
ion homeostasis GO:0050801 230 0.028
Rat
regulation of kinase activity GO:0043549 314 0.028
Mouse
response to hormone GO:0009725 175 0.028
Rat
cellular chemical homeostasis GO:0055082 180 0.028
Rat
female gamete generation GO:0007292 2 0.028
positive regulation of peptidase activity GO:0010952 88 0.028
cognition GO:0050890 43 0.027
negative regulation of developmental process GO:0051093 247 0.027
cell junction organization GO:0034330 79 0.027
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.027
Rat
positive regulation of response to wounding GO:1903036 28 0.027
Rat
circulatory system process GO:0003013 113 0.027
positive regulation of endopeptidase activity GO:0010950 84 0.027
cytoplasmic transport GO:0016482 379 0.027
cell substrate adherens junction assembly GO:0007045 30 0.027
midbrain development GO:0030901 45 0.027
substrate adhesion dependent cell spreading GO:0034446 41 0.026
regulation of stress fiber assembly GO:0051492 32 0.026
positive regulation of transferase activity GO:0051347 227 0.026
Mouse
granulocyte chemotaxis GO:0071621 37 0.026
negative regulation of cell death GO:0060548 345 0.025
myeloid leukocyte migration GO:0097529 62 0.025
cellular lipid metabolic process GO:0044255 303 0.025
regulation of secretion GO:0051046 194 0.025
protein tetramerization GO:0051262 47 0.025
establishment of protein localization to plasma membrane GO:0090002 68 0.025
positive regulation of cell matrix adhesion GO:0001954 23 0.025
establishment of protein localization to membrane GO:0090150 121 0.025
positive regulation of adherens junction organization GO:1903393 12 0.024
positive regulation of kinase activity GO:0033674 204 0.024
Mouse
leukocyte chemotaxis GO:0030595 76 0.024
regulation of growth GO:0040008 165 0.024
regulation of protein localization GO:0032880 296 0.024
spermatid differentiation GO:0048515 4 0.024
cyclic nucleotide metabolic process GO:0009187 82 0.024
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.024
oogenesis GO:0048477 2 0.023
positive regulation of cell proliferation GO:0008284 301 0.023
Rat
positive regulation of cell junction assembly GO:1901890 11 0.023
regulation of substrate adhesion dependent cell spreading GO:1900024 19 0.023
actin filament bundle organization GO:0061572 54 0.023
response to organic cyclic compound GO:0014070 204 0.022
Rat
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.022
purine ribonucleotide biosynthetic process GO:0009152 79 0.022
regulation of cell projection organization GO:0031344 107 0.022
cyclic purine nucleotide metabolic process GO:0052652 60 0.022
metal ion homeostasis GO:0055065 169 0.022
Rat
regulation of map kinase activity GO:0043405 108 0.022
Mouse
activation of cysteine type endopeptidase activity GO:0097202 57 0.022
regulation of reactive oxygen species metabolic process GO:2000377 41 0.022
Rat
actin filament bundle assembly GO:0051017 54 0.021
adherens junction assembly GO:0034333 34 0.021
peptidyl tyrosine modification GO:0018212 170 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
Rat
positive regulation of map kinase activity GO:0043406 80 0.021
Mouse
head development GO:0060322 108 0.021
Rat
cellular response to cytokine stimulus GO:0071345 181 0.021
negative regulation of protein maturation GO:1903318 142 0.021
positive regulation of synaptic transmission GO:0050806 4 0.021
regeneration GO:0031099 4 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
actin mediated cell contraction GO:0070252 12 0.020
nucleoside phosphate biosynthetic process GO:1901293 109 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
protein catabolic process GO:0030163 325 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
blood circulation GO:0008015 113 0.020
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.020
spermatid development GO:0007286 4 0.020
membrane assembly GO:0071709 10 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
Rat
mitotic cell cycle GO:0000278 326 0.020
adherens junction organization GO:0034332 36 0.020
hemopoiesis GO:0030097 180 0.019
generation of neurons GO:0048699 152 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
brain development GO:0007420 97 0.019
Rat
neutrophil migration GO:1990266 25 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
cellular ion homeostasis GO:0006873 168 0.019
neural nucleus development GO:0048857 47 0.019
chromatin modification GO:0016568 298 0.019
anion transport GO:0006820 161 0.019
cell substrate junction assembly GO:0007044 35 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.018
protein localization to organelle GO:0033365 280 0.018
regulation of cell cycle process GO:0010564 266 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
cellular metal ion homeostasis GO:0006875 146 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
reactive nitrogen species metabolic process GO:2001057 3 0.018
negative regulation of protein modification process GO:0031400 200 0.018
Rat
regulation of membrane potential GO:0042391 95 0.018
regulation of hormone levels GO:0010817 125 0.018
histone modification GO:0016570 251 0.018
substantia nigra development GO:0021762 45 0.018
cell activation GO:0001775 213 0.017
growth GO:0040007 202 0.017
visual behavior GO:0007632 2 0.017
positive regulation of transport GO:0051050 336 0.017
Rat
regulation of intracellular transport GO:0032386 195 0.017
response to organonitrogen compound GO:0010243 156 0.017
regulation of system process GO:0044057 101 0.017
associative learning GO:0008306 1 0.017
ribonucleotide biosynthetic process GO:0009260 81 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.017
regulation of nervous system development GO:0051960 88 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
regulation of secretion by cell GO:1903530 177 0.017
peripheral nervous system development GO:0007422 2 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
Rat
neutrophil chemotaxis GO:0030593 24 0.017
dephosphorylation GO:0016311 209 0.017
regulation of protein transport GO:0051223 213 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
positive regulation of secretion by cell GO:1903532 108 0.017
regulation of cellular response to stress GO:0080135 244 0.017
Mouse
negative regulation of intracellular signal transduction GO:1902532 183 0.017
adult locomotory behavior GO:0008344 1 0.017
negative regulation of transport GO:0051051 176 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.016
protein ubiquitination GO:0016567 314 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
Rat
positive regulation of stress fiber assembly GO:0051496 22 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
Rat
neuron differentiation GO:0030182 138 0.016
erk1 and erk2 cascade GO:0070371 104 0.016
mitotic cell cycle process GO:1903047 286 0.016
activation of mapk activity GO:0000187 45 0.016
regulation of protein processing GO:0070613 150 0.016
action potential GO:0001508 34 0.016
regulation of protein catabolic process GO:0042176 155 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
segmentation GO:0035282 4 0.016
oocyte development GO:0048599 1 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.015
intracellular protein transport GO:0006886 270 0.015
cell cell junction organization GO:0045216 69 0.015
maintenance of location GO:0051235 112 0.015
striated muscle contraction GO:0006941 52 0.015
regulation of cell cycle GO:0051726 393 0.015
lipid biosynthetic process GO:0008610 177 0.015
angiogenesis GO:0001525 147 0.015
synaptic transmission cholinergic GO:0007271 2 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.015
homotypic cell cell adhesion GO:0034109 47 0.015
second messenger mediated signaling GO:0019932 78 0.015
chromatin organization GO:0006325 351 0.015
cyclic nucleotide biosynthetic process GO:0009190 61 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.014
Rat
reactive oxygen species biosynthetic process GO:1903409 4 0.014
positive regulation of actin filament bundle assembly GO:0032233 25 0.014
cation homeostasis GO:0055080 189 0.014
Rat
actin filament based movement GO:0030048 17 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.014
regulation of erk1 and erk2 cascade GO:0070372 99 0.014
regulation of protein secretion GO:0050708 86 0.014
actomyosin structure organization GO:0031032 59 0.014
protein targeting GO:0006605 187 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
oocyte differentiation GO:0009994 2 0.014
regulation of cytokine production GO:0001817 232 0.014
cell projection morphogenesis GO:0048858 129 0.014
positive regulation of transporter activity GO:0032411 32 0.014
Rat
response to peptide GO:1901652 65 0.014
circadian behavior GO:0048512 2 0.014
regulation of immune effector process GO:0002697 91 0.014
blastoderm segmentation GO:0007350 2 0.014
circulatory system development GO:0072359 262 0.014
microtubule based process GO:0007017 210 0.014
oxidation reduction process GO:0055114 396 0.014
regulation of calcium ion transmembrane transport GO:1903169 28 0.014
negative regulation of transferase activity GO:0051348 124 0.014
blood vessel development GO:0001568 172 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.013
nuclear transport GO:0051169 179 0.013
nitrogen compound transport GO:0071705 191 0.013
cell growth GO:0016049 160 0.013
negative regulation of organelle organization GO:0010639 126 0.013
regulation of nucleotide biosynthetic process GO:0030808 50 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
cell fate determination GO:0001709 3 0.013
response to oxidative stress GO:0006979 121 0.013
Rat
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
Rat
sensory perception of pain GO:0019233 4 0.013
response to radiation GO:0009314 151 0.013
phospholipid metabolic process GO:0006644 99 0.013
cell division GO:0051301 168 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
multi organism cellular process GO:0044764 156 0.013

AGER disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.103
sensory system disease DOID:0050155 203 0.049
nervous system disease DOID:863 431 0.049
musculoskeletal system disease DOID:17 223 0.033
eye and adnexa disease DOID:1492 150 0.029
eye disease DOID:5614 149 0.026
acquired metabolic disease DOID:0060158 58 0.026
immune system disease DOID:2914 155 0.025
connective tissue disease DOID:65 109 0.019
retinal disease DOID:5679 118 0.017
central nervous system disease DOID:331 186 0.016
inherited metabolic disorder DOID:655 242 0.016
neurodegenerative disease DOID:1289 102 0.015
muscular disease DOID:0080000 114 0.014
disease of cellular proliferation DOID:14566 174 0.013
bone disease DOID:0080001 88 0.013
retinal degeneration DOID:8466 89 0.013