Homo sapiens

0 known processes

DIO1

deiodinase, iodothyronine, type I

(Aliases: 5DI,MGC130051,MGC130050,TXDI1)

DIO1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anion transport GO:0006820 161 0.203
cellular amino acid metabolic process GO:0006520 116 0.120
Human
vitamin k catabolic process GO:0042377 2 0.101
negative regulation of icosanoid secretion GO:0032304 2 0.088
organic anion transport GO:0015711 103 0.088
vitamin e metabolic process GO:0042360 1 0.086
carboxylic acid transport GO:0046942 63 0.083
small molecule biosynthetic process GO:0044283 157 0.082
phylloquinone metabolic process GO:0042374 2 0.081
cellular ketone metabolic process GO:0042180 80 0.078
ketone catabolic process GO:0042182 3 0.072
monocarboxylic acid metabolic process GO:0032787 185 0.069
epoxygenase p450 pathway GO:0019373 3 0.068
phylloquinone catabolic process GO:0042376 2 0.063
leukotriene b4 metabolic process GO:0036102 2 0.062
post embryonic development GO:0009791 2 0.062
lipid metabolic process GO:0006629 381 0.060
organic hydroxy compound metabolic process GO:1901615 147 0.057
Human
vitamin k biosynthetic process GO:0042371 2 0.057
long chain fatty acid metabolic process GO:0001676 30 0.057
icosanoid catabolic process GO:1901523 2 0.057
fatty acid omega oxidation GO:0010430 2 0.055
quinone catabolic process GO:1901662 2 0.054
cellular lipid metabolic process GO:0044255 303 0.054
thyroid hormone transport GO:0070327 2 0.051
fatty acid derivative catabolic process GO:1901569 2 0.050
leukotriene catabolic process GO:0036100 2 0.050
oxidation reduction process GO:0055114 396 0.050
Human Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.048
cofactor metabolic process GO:0051186 87 0.047
organic acid transport GO:0015849 65 0.046
protein processing GO:0016485 226 0.046
regulation of hormone levels GO:0010817 125 0.046
Human
cellular amine metabolic process GO:0044106 41 0.045
response to oxygen containing compound GO:1901700 369 0.043
organic acid biosynthetic process GO:0016053 97 0.041
carboxylic acid biosynthetic process GO:0046394 97 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
chemical homeostasis GO:0048878 306 0.040
negative regulation of protein metabolic process GO:0051248 391 0.040
ion transmembrane transport GO:0034220 338 0.040
transmembrane transport GO:0055085 399 0.039
response to organic cyclic compound GO:0014070 204 0.039
menaquinone catabolic process GO:0042361 2 0.038
steroid metabolic process GO:0008202 94 0.036
sulfur compound metabolic process GO:0006790 101 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
amine metabolic process GO:0009308 44 0.035
protein maturation GO:0051604 233 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.035
hormone metabolic process GO:0042445 61 0.035
Human
urate transport GO:0015747 3 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.032
fatty acid metabolic process GO:0006631 115 0.031
lipid biosynthetic process GO:0008610 177 0.030
multicellular organismal aging GO:0010259 3 0.030
nucleotide catabolic process GO:0009166 408 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
anion transmembrane transport GO:0098656 76 0.029
regeneration GO:0031099 4 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
small molecule catabolic process GO:0044282 92 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
purine containing compound catabolic process GO:0072523 411 0.028
ion homeostasis GO:0050801 230 0.028
regulation of protein maturation GO:1903317 150 0.027
determination of adult lifespan GO:0008340 2 0.027
regulation of response to external stimulus GO:0032101 222 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
defense response GO:0006952 315 0.027
regulation of protein processing GO:0070613 150 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
coenzyme metabolic process GO:0006732 65 0.026
negative regulation of protein maturation GO:1903318 142 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
female gamete generation GO:0007292 2 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
cellular modified amino acid metabolic process GO:0006575 64 0.025
Human
negative regulation of catalytic activity GO:0043086 335 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
negative regulation of protein processing GO:0010955 142 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
organophosphate catabolic process GO:0046434 430 0.024
cellular homeostasis GO:0019725 196 0.024
oogenesis GO:0048477 2 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
cytoplasmic transport GO:0016482 379 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
secretion GO:0046903 254 0.024
response to nitrogen compound GO:1901698 184 0.024
inorganic anion transmembrane transport GO:0098661 47 0.024
icosanoid metabolic process GO:0006690 35 0.023
cation transport GO:0006812 331 0.023
menaquinone metabolic process GO:0009233 3 0.023
cation homeostasis GO:0055080 189 0.023
response to hormone GO:0009725 175 0.023
response to lipid GO:0033993 206 0.023
alpha ketoglutarate transport GO:0015742 1 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
cellular response to endogenous stimulus GO:0071495 336 0.022
regulation of response to wounding GO:1903034 101 0.022
regulation of proteolysis GO:0030162 293 0.022
cellular chemical homeostasis GO:0055082 180 0.021
regulation of peptidase activity GO:0052547 180 0.021
response to other organism GO:0051707 261 0.021
organic acid catabolic process GO:0016054 71 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
carboxylic acid catabolic process GO:0046395 71 0.021
reactive oxygen species metabolic process GO:0072593 75 0.021
nitrogen compound transport GO:0071705 191 0.021
monocarboxylic acid biosynthetic process GO:0072330 67 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
response to external biotic stimulus GO:0043207 261 0.021
response to biotic stimulus GO:0009607 276 0.021
locomotory behavior GO:0007626 1 0.020
positive regulation of transport GO:0051050 336 0.020
cellular hormone metabolic process GO:0034754 41 0.020
negative regulation of proteolysis GO:0045861 132 0.020
isoquinoline alkaloid metabolic process GO:0033076 1 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
immune response GO:0006955 307 0.020
primary alcohol metabolic process GO:0034308 17 0.020
segmentation GO:0035282 4 0.020
renal water homeostasis GO:0003091 4 0.020
lipid catabolic process GO:0016042 84 0.020
metal ion homeostasis GO:0055065 169 0.020
cation transmembrane transport GO:0098655 238 0.020
vesicle mediated transport GO:0016192 371 0.020
single organism cellular localization GO:1902580 332 0.019
regulation of protein localization GO:0032880 296 0.019
unsaturated fatty acid metabolic process GO:0033559 37 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
lipid transport GO:0006869 90 0.019
lipid modification GO:0030258 84 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
response to fungus GO:0009620 4 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
regulation of secretion GO:0051046 194 0.019
nucleoside catabolic process GO:0009164 408 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
atp metabolic process GO:0046034 176 0.018
response to xenobiotic stimulus GO:0009410 30 0.018
regulation of cell differentiation GO:0045595 393 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
cellular response to genistein GO:0071412 1 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
protein localization to organelle GO:0033365 280 0.018
positive regulation of immune system process GO:0002684 283 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
ras protein signal transduction GO:0007265 73 0.018
cell adhesion GO:0007155 325 0.018
cellular lipid catabolic process GO:0044242 65 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
cellular response to hormone stimulus GO:0032870 125 0.017
multi organism cellular process GO:0044764 156 0.017
protein targeting GO:0006605 187 0.017
fatty acid derivative metabolic process GO:1901568 35 0.017
regulation of transferase activity GO:0051338 355 0.017
organic hydroxy compound transport GO:0015850 63 0.017
renal system process involved in regulation of blood volume GO:0001977 4 0.017
apoptotic signaling pathway GO:0097190 268 0.017
lipid localization GO:0010876 106 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
biological adhesion GO:0022610 331 0.017
interspecies interaction between organisms GO:0044419 156 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
growth GO:0040007 202 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
response to wounding GO:0009611 168 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
inorganic anion transport GO:0015698 60 0.016
androgen biosynthetic process GO:0006702 3 0.016
pressure natriuresis GO:0003095 2 0.016
system process GO:0003008 349 0.016
alpha amino acid metabolic process GO:1901605 72 0.016
response to inorganic substance GO:0010035 127 0.016
actin filament based process GO:0030029 224 0.016
memory GO:0007613 3 0.016
carbohydrate metabolic process GO:0005975 207 0.016
testosterone biosynthetic process GO:0061370 2 0.016
positive regulation of catabolic process GO:0009896 310 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
cell morphogenesis GO:0000902 296 0.016
response to cytokine GO:0034097 232 0.016
multicellular organismal response to stress GO:0033555 1 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
response to abiotic stimulus GO:0009628 336 0.016
cellular ion homeostasis GO:0006873 168 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.015
oocyte development GO:0048599 1 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
protein catabolic process GO:0030163 325 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
mitochondrion organization GO:0007005 156 0.015
neuromuscular junction development GO:0007528 3 0.015
tripartite regional subdivision GO:0007351 2 0.015
secretion by cell GO:0032940 226 0.015
sequestering of calcium ion GO:0051208 17 0.015
cofactor biosynthetic process GO:0051188 31 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
oocyte differentiation GO:0009994 2 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
tissue regeneration GO:0042246 3 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
mitotic cell cycle GO:0000278 326 0.015
alcohol metabolic process GO:0006066 114 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
cellular cation homeostasis GO:0030003 163 0.014
metal ion transport GO:0030001 272 0.014
anterior posterior axis specification GO:0009948 2 0.014
dephosphorylation GO:0016311 209 0.014
response to bacterium GO:0009617 144 0.014
regulation of body fluid levels GO:0050878 99 0.014
negative regulation of protein modification process GO:0031400 200 0.014
blastoderm segmentation GO:0007350 2 0.014
wound healing GO:0042060 115 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
positive regulation of organic acid transport GO:0032892 3 0.014
intracellular protein transport GO:0006886 270 0.014
viral life cycle GO:0019058 132 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
negative regulation of transport GO:0051051 176 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
divalent inorganic cation transport GO:0072511 158 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
regulation of cellular response to stress GO:0080135 244 0.014
cell growth GO:0016049 160 0.014
glycine import GO:0036233 1 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
regulation of ion transport GO:0043269 189 0.014
positive regulation of plasminogen activation GO:0010756 3 0.014
negative regulation of peptidase activity GO:0010466 91 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
regulation of phospholipase c activating g protein coupled receptor signaling pathway GO:1900736 1 0.013
innate immune response GO:0045087 178 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
maintenance of location GO:0051235 112 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
cellular protein complex assembly GO:0043623 188 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
glycoprotein metabolic process GO:0009100 110 0.013
sialic acid transport GO:0015739 1 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
atp catabolic process GO:0006200 157 0.013
regulation of protein kinase activity GO:0045859 289 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
salivary gland morphogenesis GO:0007435 4 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
response to drug GO:0042493 81 0.013
regulation of kinase activity GO:0043549 314 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
defense response to bacterium GO:0042742 63 0.013
viral process GO:0016032 146 0.013
response to steroid hormone GO:0048545 80 0.013
cellular protein catabolic process GO:0044257 261 0.013
negative regulation of cell cycle GO:0045786 193 0.013
vitamin metabolic process GO:0006766 26 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
adult locomotory behavior GO:0008344 1 0.013
membrane organization GO:0061024 292 0.013
regulation of locomotion GO:0040012 329 0.013
hindbrain development GO:0030902 3 0.013
cellular amide metabolic process GO:0043603 69 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
sequestering of metal ion GO:0051238 24 0.012
regulation of cell cycle GO:0051726 393 0.012
ketone biosynthetic process GO:0042181 17 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
cellular response to external stimulus GO:0071496 111 0.012
defense response to other organism GO:0098542 129 0.012
positive regulation of fatty acid transport GO:2000193 3 0.012
rho protein signal transduction GO:0007266 26 0.012
leukotriene b4 catabolic process GO:0036101 2 0.012
organelle assembly GO:0070925 176 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
regulation of protein transport GO:0051223 213 0.012
carnitine transmembrane transport GO:1902603 3 0.012
response to extracellular stimulus GO:0009991 85 0.012
cellular component morphogenesis GO:0032989 314 0.012
divalent metal ion transport GO:0070838 152 0.012
multicellular organismal homeostasis GO:0048871 67 0.012
arachidonic acid metabolic process GO:0019369 14 0.012
regulation of cell cycle process GO:0010564 266 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
positive regulation of cell death GO:0010942 263 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
response to nutrient levels GO:0031667 81 0.012
retinoic acid biosynthetic process GO:0002138 2 0.012
immune effector process GO:0002252 159 0.012
single organism membrane organization GO:0044802 268 0.012
protein secretion GO:0009306 98 0.012
regulation of cellular component movement GO:0051270 334 0.012
cell projection assembly GO:0030031 126 0.012
cell projection organization GO:0030030 252 0.012
endomembrane system organization GO:0010256 196 0.012
nervous system development GO:0007399 293 0.012
mitotic cell cycle process GO:1903047 286 0.012
organic hydroxy compound biosynthetic process GO:1901617 71 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
lung alveolus development GO:0048286 4 0.012
diterpenoid biosynthetic process GO:0016102 2 0.011
drug metabolic process GO:0017144 19 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
response to axon injury GO:0048678 1 0.011
negative regulation of developmental process GO:0051093 247 0.011
anatomical structure homeostasis GO:0060249 100 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
nuclear transport GO:0051169 179 0.011
regulation of intracellular transport GO:0032386 195 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
chloride transport GO:0006821 41 0.011
mapk cascade GO:0000165 288 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cellular response to lipid GO:0071396 127 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
calcium ion transport GO:0006816 147 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
positive regulation of transferase activity GO:0051347 227 0.011
negative regulation of cell death GO:0060548 345 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
regulation of multi organism process GO:0043900 157 0.011
regulation of cell migration GO:0030334 289 0.011
regulation of homeostatic process GO:0032844 121 0.011
endocytosis GO:0006897 159 0.011
rna processing GO:0006396 255 0.011
sensory perception GO:0007600 103 0.011
negative regulation of response to external stimulus GO:0032102 83 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
positive regulation of cell migration GO:0030335 172 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
renal tubular secretion GO:0097254 1 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
microtubule based process GO:0007017 210 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
short chain fatty acid import GO:0015913 1 0.011
spermatid development GO:0007286 4 0.011
negative regulation of response to wounding GO:1903035 47 0.011
regulation of cell growth GO:0001558 135 0.011
regulation of wound healing GO:0061041 56 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
cilium morphogenesis GO:0060271 75 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
negative regulation of cellular organohalogen metabolic process GO:0090349 1 0.010
response to activity GO:0014823 0 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
limbic system development GO:0021761 3 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
protein oligomerization GO:0051259 173 0.010
compound eye development GO:0048749 1 0.010
regulation of protein catabolic process GO:0042176 155 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
lipid oxidation GO:0034440 33 0.010
protein homooligomerization GO:0051260 100 0.010
gtp catabolic process GO:0006184 237 0.010
myoblast fusion GO:0007520 1 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
chromatin organization GO:0006325 351 0.010
visual behavior GO:0007632 2 0.010
regulation of icosanoid secretion GO:0032303 4 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
positive regulation of secretion GO:0051047 116 0.010
response to organonitrogen compound GO:0010243 156 0.010
thymus development GO:0048538 3 0.010
cytokine production GO:0001816 247 0.010

DIO1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.108
inherited metabolic disorder DOID:655 242 0.102
sensory system disease DOID:0050155 203 0.030
eye and adnexa disease DOID:1492 150 0.030
nervous system disease DOID:863 431 0.030
eye disease DOID:5614 149 0.030
immune system disease DOID:2914 155 0.027
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.020
hematopoietic system disease DOID:74 100 0.016
musculoskeletal system disease DOID:17 223 0.016
urinary system disease DOID:18 40 0.016
retinal disease DOID:5679 118 0.015
central nervous system disease DOID:331 186 0.014
amino acid metabolic disorder DOID:9252 50 0.014
neurodegenerative disease DOID:1289 102 0.012
kidney disease DOID:557 36 0.012
bone disease DOID:0080001 88 0.012
connective tissue disease DOID:65 109 0.012
primary ciliary dyskinesia DOID:9562 27 0.011
retinal degeneration DOID:8466 89 0.011
lipid metabolism disorder DOID:3146 26 0.011
steroid inherited metabolic disorder DOID:1701 9 0.011