Homo sapiens

5 known processes

CRYL1

crystallin, lambda 1

(Aliases: GDH,MGC149525,MGC149526,lambda-CRY)

CRYL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.205
oxidation reduction process GO:0055114 396 0.179
lipid metabolic process GO:0006629 381 0.111
cellular lipid metabolic process GO:0044255 303 0.098
cellular modified amino acid metabolic process GO:0006575 64 0.090
cofactor metabolic process GO:0051186 87 0.085
sulfur compound metabolic process GO:0006790 101 0.080
glutathione metabolic process GO:0006749 20 0.077
amine metabolic process GO:0009308 44 0.071
response to oxygen containing compound GO:1901700 369 0.069
cellular ketone metabolic process GO:0042180 80 0.057
small molecule catabolic process GO:0044282 92 0.053
post embryonic development GO:0009791 2 0.052
monocarboxylic acid metabolic process GO:0032787 185 0.052
cation transport GO:0006812 331 0.049
cellular amine metabolic process GO:0044106 41 0.049
metal ion transport GO:0030001 272 0.045
anion transport GO:0006820 161 0.043
response to abiotic stimulus GO:0009628 336 0.040
transmembrane transport GO:0055085 399 0.039
coenzyme metabolic process GO:0006732 65 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
regulation of cellular ketone metabolic process GO:0010565 50 0.035
small molecule biosynthetic process GO:0044283 157 0.035
response to organic cyclic compound GO:0014070 204 0.034
cellular amide metabolic process GO:0043603 69 0.034
organophosphate catabolic process GO:0046434 430 0.034
defense response GO:0006952 315 0.034
negative regulation of protein metabolic process GO:0051248 391 0.033
fatty acid metabolic process GO:0006631 115 0.033
single organism membrane organization GO:0044802 268 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
carbohydrate metabolic process GO:0005975 207 0.031
nitrogen compound transport GO:0071705 191 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
nucleotide catabolic process GO:0009166 408 0.031
multicellular organismal aging GO:0010259 3 0.031
glycosyl compound catabolic process GO:1901658 413 0.031
determination of adult lifespan GO:0008340 2 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
organonitrogen compound biosynthetic process GO:1901566 200 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
nucleoside triphosphate catabolic process GO:0009143 394 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
organic acid catabolic process GO:0016054 71 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.028
positive regulation of transport GO:0051050 336 0.028
alcohol metabolic process GO:0006066 114 0.028
chemical homeostasis GO:0048878 306 0.028
locomotory behavior GO:0007626 1 0.028
peptide metabolic process GO:0006518 51 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
organic hydroxy compound metabolic process GO:1901615 147 0.027
regulation of proteolysis GO:0030162 293 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
response to external biotic stimulus GO:0043207 261 0.027
protein processing GO:0016485 226 0.026
cellular homeostasis GO:0019725 196 0.026
membrane organization GO:0061024 292 0.026
vesicle mediated transport GO:0016192 371 0.026
nucleoside catabolic process GO:0009164 408 0.026
nucleoside monophosphate metabolic process GO:0009123 191 0.026
regulation of peptidase activity GO:0052547 180 0.026
oogenesis GO:0048477 2 0.026
cellular lipid catabolic process GO:0044242 65 0.026
organic anion transport GO:0015711 103 0.026
female gamete generation GO:0007292 2 0.026
carboxylic acid catabolic process GO:0046395 71 0.025
immune response GO:0006955 307 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
protein maturation GO:0051604 233 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
cellular response to oxygen containing compound GO:1901701 276 0.025
response to lipid GO:0033993 206 0.025
divalent metal ion transport GO:0070838 152 0.024
lipid biosynthetic process GO:0008610 177 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
cytoplasmic transport GO:0016482 379 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
divalent inorganic cation transport GO:0072511 158 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
single organism membrane fusion GO:0044801 37 0.023
response to inorganic substance GO:0010035 127 0.023
regeneration GO:0031099 4 0.023
organic acid biosynthetic process GO:0016053 97 0.023
lipid modification GO:0030258 84 0.023
rhythmic behavior GO:0007622 2 0.022
system process GO:0003008 349 0.022
response to hormone GO:0009725 175 0.022
response to metal ion GO:0010038 84 0.022
atp catabolic process GO:0006200 157 0.022
innate immune response GO:0045087 178 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
ras protein signal transduction GO:0007265 73 0.021
memory GO:0007613 3 0.021
cation homeostasis GO:0055080 189 0.021
epithelium development GO:0060429 227 0.021
purine containing compound catabolic process GO:0072523 411 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
cadmium ion transport GO:0015691 2 0.021
segmentation GO:0035282 4 0.021
response to organonitrogen compound GO:0010243 156 0.020
response to biotic stimulus GO:0009607 276 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
ion transmembrane transport GO:0034220 338 0.020
regulation of protein maturation GO:1903317 150 0.020
carboxylic acid biosynthetic process GO:0046394 97 0.020
response to nitrogen compound GO:1901698 184 0.020
negative regulation of cell proliferation GO:0008285 228 0.019
protein oligomerization GO:0051259 173 0.019
apoptotic signaling pathway GO:0097190 268 0.019
negative regulation of cell death GO:0060548 345 0.019
circadian behavior GO:0048512 2 0.019
nervous system development GO:0007399 293 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
organic acid transport GO:0015849 65 0.019
secretion by cell GO:0032940 226 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
blastoderm segmentation GO:0007350 2 0.019
nucleoside monophosphate catabolic process GO:0009125 159 0.019
reactive oxygen species metabolic process GO:0072593 75 0.018
epithelial cell differentiation GO:0030855 141 0.018
protein ubiquitination GO:0016567 314 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
ion homeostasis GO:0050801 230 0.018
protein catabolic process GO:0030163 325 0.018
neuromuscular junction development GO:0007528 3 0.018
regulation of hormone levels GO:0010817 125 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
response to axon injury GO:0048678 1 0.018
atp metabolic process GO:0046034 176 0.018
regulation of protein processing GO:0070613 150 0.018
secretion GO:0046903 254 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.017
regulation of cellular response to stress GO:0080135 244 0.017
cellular protein catabolic process GO:0044257 261 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
response to other organism GO:0051707 261 0.017
regulation of protein localization GO:0032880 296 0.017
regulation of cytokine production GO:0001817 232 0.017
dephosphorylation GO:0016311 209 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
cytokine production GO:0001816 247 0.017
phospholipid metabolic process GO:0006644 99 0.017
cellular component morphogenesis GO:0032989 314 0.017
cell morphogenesis GO:0000902 296 0.017
single organism cellular localization GO:1902580 332 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
regulation of cell cycle GO:0051726 393 0.016
actin filament based process GO:0030029 224 0.016
positive regulation of cell death GO:0010942 263 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of transferase activity GO:0051338 355 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
regulation of cell differentiation GO:0045595 393 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of cell motility GO:2000145 299 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
glycerophospholipid metabolic process GO:0006650 84 0.016
glycerolipid metabolic process GO:0046486 107 0.016
nadph oxidation GO:0070995 3 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
positive regulation of catabolic process GO:0009896 310 0.015
mitotic cell cycle GO:0000278 326 0.015
cell development GO:0048468 328 0.015
adult locomotory behavior GO:0008344 1 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
response to bacterium GO:0009617 144 0.015
peripheral nervous system development GO:0007422 2 0.015
response to acid chemical GO:0001101 66 0.015
carboxylic acid transport GO:0046942 63 0.015
long chain fatty acid metabolic process GO:0001676 30 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
cell projection organization GO:0030030 252 0.015
response to drug GO:0042493 81 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
histone modification GO:0016570 251 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
response to cytokine GO:0034097 232 0.015
regulation of secretion by cell GO:1903530 177 0.015
mapk cascade GO:0000165 288 0.015
negative regulation of protein modification process GO:0031400 200 0.014
negative regulation of developmental process GO:0051093 247 0.014
steroid metabolic process GO:0008202 94 0.014
regulation of immune response GO:0050776 201 0.014
spermatid differentiation GO:0048515 4 0.014
negative regulation of protein maturation GO:1903318 142 0.014
cell adhesion GO:0007155 325 0.014
positive regulation of developmental process GO:0051094 314 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
regulation of cell cycle process GO:0010564 266 0.014
compound eye development GO:0048749 1 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
organelle fusion GO:0048284 36 0.014
regulation of response to external stimulus GO:0032101 222 0.014
phosphatidylethanolamine biosynthetic process GO:0006646 4 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
cation transmembrane transport GO:0098655 238 0.014
oocyte development GO:0048599 1 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
oocyte differentiation GO:0009994 2 0.014
positive regulation of organelle organization GO:0010638 195 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
negative regulation of collagen metabolic process GO:0010713 3 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
regulation of cellular component movement GO:0051270 334 0.014
hindbrain development GO:0030902 3 0.014
cellular chemical homeostasis GO:0055082 180 0.014
sleep GO:0030431 2 0.014
intracellular protein transport GO:0006886 270 0.014
regulation of protein transport GO:0051223 213 0.014
neurological system process GO:0050877 163 0.014
response to wounding GO:0009611 168 0.014
response to extracellular stimulus GO:0009991 85 0.013
cellular response to lipid GO:0071396 127 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
negative regulation of protein processing GO:0010955 142 0.013
negative regulation of cell cycle GO:0045786 193 0.013
cellular ion homeostasis GO:0006873 168 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of ion transport GO:0043269 189 0.013
negative regulation of proteolysis GO:0045861 132 0.013
growth GO:0040007 202 0.013
tissue regeneration GO:0042246 3 0.013
protein localization to organelle GO:0033365 280 0.013
spermatid development GO:0007286 4 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
regulation of locomotion GO:0040012 329 0.013
regulation of kinase activity GO:0043549 314 0.013
metal ion homeostasis GO:0055065 169 0.013
calcium ion transport GO:0006816 147 0.013
membrane fusion GO:0061025 43 0.013
microtubule based process GO:0007017 210 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
cellular cation homeostasis GO:0030003 163 0.013
glycoprotein metabolic process GO:0009100 110 0.013
biological adhesion GO:0022610 331 0.013
generation of precursor metabolites and energy GO:0006091 68 0.013
regulation of protein catabolic process GO:0042176 155 0.013
metencephalon development GO:0022037 2 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
regulation of cell migration GO:0030334 289 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
circadian sleep wake cycle GO:0042745 2 0.013
response to growth factor GO:0070848 205 0.013
inner ear morphogenesis GO:0042472 4 0.013
maintenance of location GO:0051235 112 0.012
rho protein signal transduction GO:0007266 26 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
negative regulation of catabolic process GO:0009895 104 0.012
chromatin organization GO:0006325 351 0.012
dna repair GO:0006281 198 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
mitotic cell cycle process GO:1903047 286 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
cell cycle phase transition GO:0044770 173 0.012
immune system development GO:0002520 195 0.012
negative regulation of multicellular organismal metabolic process GO:0044252 3 0.012
anatomical structure homeostasis GO:0060249 100 0.012
renal system process involved in regulation of blood volume GO:0001977 4 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
cellular hormone metabolic process GO:0034754 41 0.012
neuroblast proliferation GO:0007405 4 0.012
actin mediated cell contraction GO:0070252 12 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
chromatin modification GO:0016568 298 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
cell growth GO:0016049 160 0.012
protein localization to membrane GO:0072657 160 0.012
endomembrane system organization GO:0010256 196 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
response to nutrient levels GO:0031667 81 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
anterior posterior axis specification GO:0009948 2 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
response to oxygen levels GO:0070482 100 0.012
visual behavior GO:0007632 2 0.012
positive regulation of transferase activity GO:0051347 227 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
cell activation GO:0001775 213 0.012
positive regulation of kinase activity GO:0033674 204 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
regulation of secretion GO:0051046 194 0.012
regulation of cytoskeleton organization GO:0051493 177 0.011
neurotransmitter secretion GO:0007269 4 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
regulation of protein kinase activity GO:0045859 289 0.011
covalent chromatin modification GO:0016569 254 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
actin filament based movement GO:0030048 17 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
positive regulation of secretion GO:0051047 116 0.011
hemopoiesis GO:0030097 180 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
tripartite regional subdivision GO:0007351 2 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
rna interference GO:0016246 4 0.011
regulation of mapk cascade GO:0043408 262 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
leukocyte activation GO:0045321 164 0.011
response to fungus GO:0009620 4 0.011
regulation of growth GO:0040008 165 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
epidermis morphogenesis GO:0048730 3 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of intracellular transport GO:0032386 195 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
cell division GO:0051301 168 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of defense response GO:0031347 154 0.011
organ formation GO:0048645 3 0.011
response to decreased oxygen levels GO:0036293 96 0.011
sensory perception of pain GO:0019233 4 0.011
cellular response to nutrient levels GO:0031669 69 0.011
associative learning GO:0008306 1 0.011
sensory perception GO:0007600 103 0.011
limbic system development GO:0021761 3 0.011
regulation of dna metabolic process GO:0051052 153 0.011
protein targeting GO:0006605 187 0.011
sensory perception of bitter taste GO:0050913 28 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
cerebellum development GO:0021549 2 0.011
protein homooligomerization GO:0051260 100 0.011
response to hypoxia GO:0001666 96 0.010
nerve development GO:0021675 4 0.010
transition metal ion transport GO:0000041 23 0.010
fatty acid biosynthetic process GO:0006633 46 0.010
multi organism cellular process GO:0044764 156 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
sequestering of metal ion GO:0051238 24 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
positive regulation of cell migration GO:0030335 172 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
negative regulation of immune system process GO:0002683 136 0.010
central nervous system development GO:0007417 123 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.010
gtp metabolic process GO:0046039 239 0.010
positive regulation of cell motility GO:2000147 177 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
sequestering of calcium ion GO:0051208 17 0.010
rna processing GO:0006396 255 0.010
cellular response to oxidative stress GO:0034599 85 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
single organism cell adhesion GO:0098602 179 0.010
lipid catabolic process GO:0016042 84 0.010
cranial nerve development GO:0021545 4 0.010
negative regulation of organelle organization GO:0010639 126 0.010
detection of stimulus GO:0051606 85 0.010
thymus development GO:0048538 3 0.010
long term memory GO:0007616 2 0.010
response to oxidative stress GO:0006979 121 0.010

CRYL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.215
inherited metabolic disorder DOID:655 242 0.171
cardiovascular system disease DOID:1287 106 0.050
vascular disease DOID:178 25 0.037
sensory system disease DOID:0050155 203 0.029
eye and adnexa disease DOID:1492 150 0.029
nervous system disease DOID:863 431 0.029
eye disease DOID:5614 149 0.029
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.020
central nervous system disease DOID:331 186 0.018
retinal disease DOID:5679 118 0.017
retinal degeneration DOID:8466 89 0.017
musculoskeletal system disease DOID:17 223 0.016
amino acid metabolic disorder DOID:9252 50 0.014
acquired metabolic disease DOID:0060158 58 0.013
connective tissue disease DOID:65 109 0.013
carbohydrate metabolic disorder DOID:2978 55 0.013
lysosomal storage disease DOID:3211 47 0.012
neurodegenerative disease DOID:1289 102 0.011
immune system disease DOID:2914 155 0.011