Homo sapiens

0 known processes

SPHK2

sphingosine kinase 2

SPHK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.053
amine metabolic process GO:0009308 44 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
determination of adult lifespan GO:0008340 2 0.036
cellular amine metabolic process GO:0044106 41 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.033
multicellular organismal aging GO:0010259 3 0.032
post embryonic development GO:0009791 2 0.032
cellular ketone metabolic process GO:0042180 80 0.031
dephosphorylation GO:0016311 209 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.028
protein ubiquitination GO:0016567 314 0.026
Human
protein modification by small protein conjugation GO:0032446 342 0.025
Human
protein catabolic process GO:0030163 325 0.025
regulation of cell cycle GO:0051726 393 0.025
Human
cellular macromolecule catabolic process GO:0044265 380 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
organic acid biosynthetic process GO:0016053 97 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
neuromuscular junction development GO:0007528 3 0.022
intracellular protein transport GO:0006886 270 0.021
Human
monocarboxylic acid metabolic process GO:0032787 185 0.021
actin filament based process GO:0030029 224 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
locomotory behavior GO:0007626 1 0.021
small molecule biosynthetic process GO:0044283 157 0.021
female gamete generation GO:0007292 2 0.021
spermatid differentiation GO:0048515 4 0.020
response to abiotic stimulus GO:0009628 336 0.020
Yeast
positive regulation of cellular component organization GO:0051130 376 0.020
regulation of kinase activity GO:0043549 314 0.020
ras protein signal transduction GO:0007265 73 0.020
cellular lipid metabolic process GO:0044255 303 0.019
Human Yeast Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.019
spermatid development GO:0007286 4 0.019
nucleoside catabolic process GO:0009164 408 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
regulation of transferase activity GO:0051338 355 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
negative regulation of protein metabolic process GO:0051248 391 0.018
immune response GO:0006955 307 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
lipid metabolic process GO:0006629 381 0.018
Human Yeast Fly
regulation of protein kinase activity GO:0045859 289 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
anterior posterior axis specification GO:0009948 2 0.018
purine containing compound catabolic process GO:0072523 411 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
single organism cellular localization GO:1902580 332 0.017
Human
ribonucleotide catabolic process GO:0009261 405 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
lipid biosynthetic process GO:0008610 177 0.017
neurotransmitter secretion GO:0007269 4 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
regulation of cytokine production GO:0001817 232 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
purine nucleotide catabolic process GO:0006195 405 0.017
regulation of proteolysis GO:0030162 293 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
protein localization to organelle GO:0033365 280 0.017
Human
cellular protein catabolic process GO:0044257 261 0.017
organophosphate catabolic process GO:0046434 430 0.017
oocyte development GO:0048599 1 0.016
innate immune response GO:0045087 178 0.016
rna processing GO:0006396 255 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
regulation of cellular response to stress GO:0080135 244 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
response to nitrogen compound GO:1901698 184 0.016
response to oxygen containing compound GO:1901700 369 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of response to external stimulus GO:0032101 222 0.015
maintenance of location GO:0051235 112 0.015
nuclear transport GO:0051169 179 0.015
Human
mitotic cell cycle process GO:1903047 286 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
oogenesis GO:0048477 2 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
Human
mitotic cell cycle GO:0000278 326 0.015
Human
blastoderm segmentation GO:0007350 2 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
cytoplasmic transport GO:0016482 379 0.015
Human
segmentation GO:0035282 4 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
regulation of locomotion GO:0040012 329 0.014
Human
vesicle mediated transport GO:0016192 371 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
mitochondrion organization GO:0007005 156 0.014
positive regulation of immune system process GO:0002684 283 0.014
positive regulation of catabolic process GO:0009896 310 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
Human
single organism membrane organization GO:0044802 268 0.014
compound eye development GO:0048749 1 0.014
regulation of immune response GO:0050776 201 0.014
nucleotide catabolic process GO:0009166 408 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
Human
rho protein signal transduction GO:0007266 26 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
positive regulation of organelle organization GO:0010638 195 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
biological adhesion GO:0022610 331 0.014
defense response GO:0006952 315 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
response to external biotic stimulus GO:0043207 261 0.013
positive regulation of cell death GO:0010942 263 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
negative regulation of protein modification process GO:0031400 200 0.013
system process GO:0003008 349 0.013
Human
positive regulation of protein phosphorylation GO:0001934 313 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
regeneration GO:0031099 4 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
monocarboxylic acid biosynthetic process GO:0072330 67 0.013
regulation of mapk cascade GO:0043408 262 0.013
oocyte differentiation GO:0009994 2 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cell division GO:0051301 168 0.013
microtubule based process GO:0007017 210 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
response to organic cyclic compound GO:0014070 204 0.013
organelle assembly GO:0070925 176 0.013
positive regulation of locomotion GO:0040017 186 0.013
Human
cellular protein complex assembly GO:0043623 188 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
response to biotic stimulus GO:0009607 276 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
mapk cascade GO:0000165 288 0.012
small molecule catabolic process GO:0044282 92 0.012
histone modification GO:0016570 251 0.012
regulation of dna metabolic process GO:0051052 153 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
membrane organization GO:0061024 292 0.012
gtp metabolic process GO:0046039 239 0.012
regulation of cellular component movement GO:0051270 334 0.012
Human
regulation of protein catabolic process GO:0042176 155 0.012
chemical homeostasis GO:0048878 306 0.012
actin cytoskeleton organization GO:0030036 207 0.012
peripheral nervous system development GO:0007422 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
regulation of protein transport GO:0051223 213 0.012
Human
response to other organism GO:0051707 261 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
Human
covalent chromatin modification GO:0016569 254 0.012
endosomal transport GO:0016197 129 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
Human
apoptotic signaling pathway GO:0097190 268 0.012
cytokine production GO:0001816 247 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
guanosine containing compound catabolic process GO:1901069 239 0.011
protein targeting GO:0006605 187 0.011
Human
transmembrane transport GO:0055085 399 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
protein processing GO:0016485 226 0.011
protein localization to membrane GO:0072657 160 0.011
chromatin organization GO:0006325 351 0.011
regulation of cell division GO:0051302 116 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
hindbrain development GO:0030902 3 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
regulation of protein localization GO:0032880 296 0.011
Human
cellular homeostasis GO:0019725 196 0.011
gtp catabolic process GO:0006184 237 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
adult locomotory behavior GO:0008344 1 0.011
nervous system development GO:0007399 293 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
Human
response to organonitrogen compound GO:0010243 156 0.011
response to fungus GO:0009620 4 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
cell adhesion GO:0007155 325 0.011
dna repair GO:0006281 198 0.011
cell projection organization GO:0030030 252 0.011
protein maturation GO:0051604 233 0.011
neurological system process GO:0050877 163 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
translation GO:0006412 132 0.011
protein import GO:0017038 130 0.011
Human
growth GO:0040007 202 0.011
Human
neural tube formation GO:0001841 3 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of growth GO:0040008 165 0.011
Human
cell fate determination GO:0001709 3 0.011
regulation of multi organism process GO:0043900 157 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
protein acylation GO:0043543 138 0.011
regulation of cell cycle process GO:0010564 266 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
regulation of phosphatase activity GO:0010921 81 0.010
tripartite regional subdivision GO:0007351 2 0.010
negative regulation of cell cycle GO:0045786 193 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
actin filament organization GO:0007015 128 0.010
regulation of cell differentiation GO:0045595 393 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
positive regulation of transferase activity GO:0051347 227 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
memory GO:0007613 3 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
single organismal cell cell adhesion GO:0016337 148 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010

SPHK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.045
nervous system disease DOID:863 431 0.045
disease of metabolism DOID:0014667 295 0.023
sensory system disease DOID:0050155 203 0.021
musculoskeletal system disease DOID:17 223 0.018
inherited metabolic disorder DOID:655 242 0.016
disease of cellular proliferation DOID:14566 174 0.015
cancer DOID:162 167 0.015
organ system cancer DOID:0050686 164 0.014
brain disease DOID:936 73 0.014
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.012
connective tissue disease DOID:65 109 0.011
epilepsy syndrome DOID:1826 41 0.011