Homo sapiens

82 known processes

EIF2C3

eukaryotic translation initiation factor 2C, 3

(Aliases: FLJ12765,MGC86946,AGO3)

EIF2C3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
production of mirnas involved in gene silencing by mirna GO:0035196 12 1.000
Human
positive regulation of mrna catabolic process GO:0061014 10 0.988
gene silencing by mirna GO:0035195 23 0.978
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.976
mrna cleavage involved in gene silencing by mirna GO:0035279 2 0.971
Human
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.971
dsrna fragmentation GO:0031050 13 0.922
Human
regulation of mrna catabolic process GO:0061013 13 0.887
production of small rna involved in gene silencing by rna GO:0070918 13 0.873
Human
negative regulation of translation involved in gene silencing by mirna GO:0035278 6 0.850
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.806
negative regulation of translation ncrna mediated GO:0040033 6 0.749
regulation of translation ncrna mediated GO:0045974 6 0.744
production of sirna involved in rna interference GO:0030422 3 0.723
translational initiation GO:0006413 48 0.677
Human
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.631
rna catabolic process GO:0006401 71 0.628
mrna catabolic process GO:0006402 56 0.620
pre mirna processing GO:0031054 8 0.596
Human
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.559
Human
cellular response to dsrna GO:0071359 19 0.479
Human
cellular macromolecule catabolic process GO:0044265 380 0.465
rna processing GO:0006396 255 0.442
Human
positive regulation of mrna metabolic process GO:1903313 19 0.426
mrna cleavage GO:0006379 5 0.382
Human
mrna processing GO:0006397 133 0.378
Human
translation GO:0006412 132 0.367
posttranscriptional gene silencing by rna GO:0035194 25 0.365
ncrna metabolic process GO:0034660 108 0.316
Human
nuclear transcribed mrna catabolic process GO:0000956 48 0.307
Human
positive regulation of mrna processing GO:0050685 17 0.281
response to dsrna GO:0043331 25 0.241
Human
mrna metabolic process GO:0016071 175 0.233
multicellular organismal aging GO:0010259 3 0.231
Worm
positive regulation of mrna 3 end processing GO:0031442 12 0.219
rna transport GO:0050658 39 0.218
regulation of translation GO:0006417 89 0.214
rna phosphodiester bond hydrolysis GO:0090501 35 0.214
Human
growth GO:0040007 202 0.207
Worm
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.203
segmentation GO:0035282 4 0.200
negative regulation of protein metabolic process GO:0051248 391 0.190
cellular response to organic cyclic compound GO:0071407 127 0.189
Human
signal transduction by phosphorylation GO:0023014 297 0.169
gene silencing by rna GO:0031047 26 0.167
regulation of mrna 3 end processing GO:0031440 12 0.166
blastoderm segmentation GO:0007350 2 0.161
targeting of mrna for destruction involved in rna interference GO:0030423 3 0.149
rna interference GO:0016246 4 0.145
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 15 0.136
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.132
cellular response to nitrogen compound GO:1901699 144 0.129
Human
regulation of stem cell proliferation GO:0072091 15 0.126
ncrna processing GO:0034470 83 0.121
Human
nucleobase containing compound transport GO:0015931 51 0.118
associative learning GO:0008306 1 0.118
posttranscriptional gene silencing GO:0016441 25 0.117
positive regulation of catabolic process GO:0009896 310 0.116
posttranscriptional regulation of gene expression GO:0010608 213 0.109
regulation of mrna metabolic process GO:1903311 53 0.097
gene silencing GO:0016458 49 0.096
system process GO:0003008 349 0.090
compound eye development GO:0048749 1 0.089
response to organic cyclic compound GO:0014070 204 0.088
Human
negative regulation of apoptotic process GO:0043066 316 0.088
cell type specific apoptotic process GO:0097285 125 0.082
determination of adult lifespan GO:0008340 2 0.078
Worm
positive regulation of wnt signaling pathway GO:0030177 54 0.078
post embryonic development GO:0009791 2 0.074
Worm
negative regulation of translation GO:0017148 37 0.072
vesicle mediated transport GO:0016192 371 0.068
single organism cellular localization GO:1902580 332 0.068
positive regulation of organelle organization GO:0010638 195 0.068
regulation of neurological system process GO:0031644 6 0.065
negative regulation of cell death GO:0060548 345 0.059
response to nitrogen compound GO:1901698 184 0.059
Human
stem cell proliferation GO:0072089 25 0.059
nuclear export GO:0051168 69 0.058
regulation of gene expression epigenetic GO:0040029 73 0.056
mapk cascade GO:0000165 288 0.054
cytoplasmic transport GO:0016482 379 0.050
intracellular protein transport GO:0006886 270 0.049
cell differentiation in spinal cord GO:0021515 1 0.049
negative regulation of cell differentiation GO:0045596 171 0.048
regulation of wnt signaling pathway GO:0030111 123 0.047
regulation of synaptic vesicle exocytosis GO:2000300 2 0.045
muscle organ development GO:0007517 56 0.045
mrna 3 end processing GO:0031124 24 0.044
regulation of translational initiation GO:0006446 24 0.043
Human
ribonucleoprotein complex localization GO:0071166 4 0.043
cellular response to nutrient levels GO:0031669 69 0.043
regulation of cellular response to stress GO:0080135 244 0.041
negative regulation of programmed cell death GO:0043069 321 0.041
amine metabolic process GO:0009308 44 0.041
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.039
neurological system process GO:0050877 163 0.038
cell development GO:0048468 328 0.038
Worm
neuron projection development GO:0031175 106 0.036
regulation of behavior GO:0050795 82 0.035
cellular component morphogenesis GO:0032989 314 0.035
cell projection organization GO:0030030 252 0.034
protein import GO:0017038 130 0.033
protein modification by small protein removal GO:0070646 92 0.033
positive regulation of developmental process GO:0051094 314 0.033
Worm
regulation of cell differentiation GO:0045595 393 0.032
anatomical structure formation involved in morphogenesis GO:0048646 284 0.032
regulation of system process GO:0044057 101 0.031
regulation of growth GO:0040008 165 0.031
Worm
locomotory behavior GO:0007626 1 0.031
protein deubiquitination GO:0016579 79 0.030
nucleocytoplasmic transport GO:0006913 176 0.029
positive regulation of immune response GO:0050778 159 0.029
forelimb morphogenesis GO:0035136 4 0.029
regulation of synaptic vesicle transport GO:1902803 3 0.029
negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000623 3 0.028
response to abiotic stimulus GO:0009628 336 0.027
positive regulation of organelle assembly GO:1902117 17 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
actin filament organization GO:0007015 128 0.026
neurotransmitter secretion GO:0007269 4 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.026
reproductive system development GO:0061458 56 0.026
Worm
rna 3 end processing GO:0031123 35 0.026
intestinal epithelial cell differentiation GO:0060575 3 0.025
hematopoietic or lymphoid organ development GO:0048534 186 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
purine nucleoside monophosphate catabolic process GO:0009128 158 0.024
cell fate determination GO:0001709 3 0.023
mrna splicing via spliceosome GO:0000398 89 0.023
regulation of neuron death GO:1901214 56 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
synaptic vesicle exocytosis GO:0016079 3 0.022
wnt signaling pathway GO:0016055 156 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
cellular amine metabolic process GO:0044106 41 0.022
motor neuron axon guidance GO:0008045 2 0.022
protein targeting to nucleus GO:0044744 104 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
response to lipid GO:0033993 206 0.021
neuron differentiation GO:0030182 138 0.021
negative regulation of translational initiation GO:0045947 7 0.021
Human
embryonic hemopoiesis GO:0035162 4 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.020
intracellular receptor signaling pathway GO:0030522 104 0.020
rna localization GO:0006403 41 0.020
regulation of neurotransmitter secretion GO:0046928 3 0.020
circadian behavior GO:0048512 2 0.019
neuromuscular junction development GO:0007528 3 0.019
establishment of rna localization GO:0051236 39 0.019
regulation of gene silencing by rna GO:0060966 6 0.019
negative regulation of transport GO:0051051 176 0.019
regeneration GO:0031099 4 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
mapk import into nucleus GO:0000189 1 0.019
regulation of kinase activity GO:0043549 314 0.019
apoptotic signaling pathway GO:0097190 268 0.018
generation of neurons GO:0048699 152 0.018
oogenesis GO:0048477 2 0.018
protein localization to organelle GO:0033365 280 0.018
actin cytoskeleton organization GO:0030036 207 0.018
mrna export from nucleus GO:0006406 29 0.018
nitrogen compound transport GO:0071705 191 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
cell part morphogenesis GO:0032990 137 0.017
sensory organ development GO:0007423 52 0.017
cellular amino acid metabolic process GO:0006520 116 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
digestive tract morphogenesis GO:0048546 56 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
cell morphogenesis GO:0000902 296 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
regulation of mrna processing GO:0050684 48 0.017
cell activation GO:0001775 213 0.017
transmembrane transport GO:0055085 399 0.017
ribonucleoprotein complex biogenesis GO:0022613 116 0.017
cell projection morphogenesis GO:0048858 129 0.017
androgen biosynthetic process GO:0006702 3 0.017
positive regulation of apoptotic process GO:0043065 246 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
secretion by cell GO:0032940 226 0.016
regulation of transferase activity GO:0051338 355 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
female gamete generation GO:0007292 2 0.016
activation of immune response GO:0002253 114 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
ras protein signal transduction GO:0007265 73 0.016
metal ion transport GO:0030001 272 0.016
behavior GO:0007610 112 0.015
myosin filament assembly GO:0031034 2 0.015
positive regulation of transport GO:0051050 336 0.015
cellular response to external stimulus GO:0071496 111 0.015
inner ear morphogenesis GO:0042472 4 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
nuclear body organization GO:0030575 4 0.015
actin filament based process GO:0030029 224 0.015
oocyte development GO:0048599 1 0.015
erbb signaling pathway GO:0038127 44 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
positive regulation of cell death GO:0010942 263 0.014
regulation of cellular component movement GO:0051270 334 0.014
regulation of neuron apoptotic process GO:0043523 35 0.014
axis elongation GO:0003401 4 0.014
regulation of protein localization GO:0032880 296 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
regulation of secretion GO:0051046 194 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
reproductive process GO:0022414 106 0.014
Worm
positive regulation of programmed cell death GO:0043068 249 0.014
organ morphogenesis GO:0009887 147 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
tube development GO:0035295 125 0.014
eye development GO:0001654 42 0.014
protein catabolic process GO:0030163 325 0.014
negative regulation of protein modification process GO:0031400 200 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
positive regulation of immune system process GO:0002684 283 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
male genitalia development GO:0030539 1 0.013
protein k63 linked deubiquitination GO:0070536 21 0.013
adult locomotory behavior GO:0008344 1 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
chromatin organization GO:0006325 351 0.013
regulation of glial cell proliferation GO:0060251 4 0.013
cellular response to extracellular stimulus GO:0031668 72 0.013
neuron death GO:0070997 65 0.013
pattern specification process GO:0007389 43 0.013
epithelium development GO:0060429 227 0.013
regulation of protein kinase activity GO:0045859 289 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
cytokine production GO:0001816 247 0.013
regulation of secretion by cell GO:1903530 177 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
rhythmic behavior GO:0007622 2 0.013
divalent inorganic cation transport GO:0072511 158 0.013
negative regulation of neuron apoptotic process GO:0043524 23 0.013
establishment of organelle localization GO:0051656 59 0.013
microtubule based process GO:0007017 210 0.013
cell cell signaling involved in cell fate commitment GO:0045168 5 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
skeletal muscle organ development GO:0060538 26 0.013
mitotic cell cycle process GO:1903047 286 0.013
protein k48 linked deubiquitination GO:0071108 19 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
lung alveolus development GO:0048286 4 0.012
cation transmembrane transport GO:0098655 238 0.012
schwann cell differentiation GO:0014037 1 0.012
negative regulation of transferase activity GO:0051348 124 0.012
oocyte differentiation GO:0009994 2 0.012
cell growth GO:0016049 160 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
cellular lipid metabolic process GO:0044255 303 0.012
developmental growth GO:0048589 48 0.012
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
mitotic cell cycle GO:0000278 326 0.012
cation transport GO:0006812 331 0.012
cell cell signaling GO:0007267 155 0.012
mitotic nuclear division GO:0007067 119 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
nervous system development GO:0007399 293 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.012
cellular response to starvation GO:0009267 58 0.012
nucleus organization GO:0006997 28 0.012
aging GO:0007568 66 0.012
Worm
divalent metal ion transport GO:0070838 152 0.012
regionalization GO:0003002 29 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
secretion GO:0046903 254 0.012
developmental programmed cell death GO:0010623 3 0.012
regulation of transmembrane transport GO:0034762 139 0.012
protein targeting GO:0006605 187 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
myosin filament organization GO:0031033 2 0.012
cellular cation homeostasis GO:0030003 163 0.012
reactive oxygen species metabolic process GO:0072593 75 0.011
negative regulation of proteolysis GO:0045861 132 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
cerebellum development GO:0021549 2 0.011
calcium ion transport GO:0006816 147 0.011
regulation of histone deacetylase activity GO:1901725 3 0.011
spermatid differentiation GO:0048515 4 0.011
ion transmembrane transport GO:0034220 338 0.011
mitochondrion organization GO:0007005 156 0.011
response to other organism GO:0051707 261 0.011
hair cycle GO:0042633 28 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
negative regulation of neuron death GO:1901215 32 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
negative regulation of cell cycle GO:0045786 193 0.011
negative regulation of catabolic process GO:0009895 104 0.011
circulatory system process GO:0003013 113 0.011
blood circulation GO:0008015 113 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
peripheral nervous system development GO:0007422 2 0.011
regulation of cytokine production GO:0001817 232 0.011
regulation of protein stability GO:0031647 87 0.011
embryonic forelimb morphogenesis GO:0035115 4 0.011
endomembrane system organization GO:0010256 196 0.011
regulation of cell development GO:0060284 161 0.011
nuclear import GO:0051170 106 0.011
regulation of cell cycle process GO:0010564 266 0.011
regulation of cell division GO:0051302 116 0.011
protein maturation GO:0051604 233 0.011
olfactory bulb interneuron differentiation GO:0021889 2 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
lung epithelial cell differentiation GO:0060487 1 0.011
regulation of intracellular transport GO:0032386 195 0.011
anatomical structure homeostasis GO:0060249 100 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.010
thymus development GO:0048538 3 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
mammary gland morphogenesis GO:0060443 2 0.010
response to axon injury GO:0048678 1 0.010
protein autophosphorylation GO:0046777 123 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
positive regulation of growth GO:0045927 58 0.010
Worm
nucleoside triphosphate catabolic process GO:0009143 394 0.010
response to lipopolysaccharide GO:0032496 70 0.010
regulation of locomotion GO:0040012 329 0.010
establishment of nucleus localization GO:0040023 1 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
lymphocyte proliferation GO:0046651 70 0.010
cell adhesion GO:0007155 325 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
protein processing GO:0016485 226 0.010
biological adhesion GO:0022610 331 0.010
negative regulation of chromosome organization GO:2001251 48 0.010

EIF2C3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.110
amino acid metabolic disorder DOID:9252 50 0.110
inherited metabolic disorder DOID:655 242 0.110
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
sensory system disease DOID:0050155 203 0.010