|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.968
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.886
|
Human Mouse |
|
|
actin crosslink formation
|
GO:0051764 |
1 |
0.466
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.401
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.348
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.326
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.318
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.296
|
|
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.291
|
Human |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.287
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.286
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.277
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.276
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.260
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.255
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.250
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.247
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.236
|
Human |
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.236
|
Human |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.216
|
Human |
|
|
tube closure
|
GO:0060606 |
3 |
0.215
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.211
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.186
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.184
|
Human |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.181
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.178
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.176
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.174
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.169
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.167
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.164
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.163
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.151
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.149
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.144
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.143
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.142
|
Human Mouse |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.142
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.141
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.135
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.128
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.128
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.125
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.123
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.120
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.118
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.115
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.114
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.113
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.107
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.106
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.102
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.101
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.099
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.098
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.097
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.096
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.093
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.093
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.091
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.089
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.089
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.088
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.087
|
Human Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.086
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.086
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.086
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.085
|
|
|
|
system process
|
GO:0003008 |
349 |
0.084
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.084
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.084
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.083
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.082
|
Human Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.080
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.080
|
|
|
|
memory
|
GO:0007613 |
3 |
0.077
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.074
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.074
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.073
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.069
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.069
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.068
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.067
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.065
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.062
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.062
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.061
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.060
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.060
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.059
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.059
|
Human Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.058
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.058
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.057
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.057
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.056
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.056
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.055
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.053
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.053
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.052
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.052
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.051
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.051
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.050
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.050
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.050
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.049
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.049
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.049
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.048
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.048
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.048
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.048
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.047
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.047
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.046
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.046
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.045
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.045
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.044
|
Mouse |
|
|
barbed end actin filament capping
|
GO:0051016 |
3 |
0.044
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.043
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.043
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.043
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.043
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.042
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.042
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.042
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.041
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.040
|
Human |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.040
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.039
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.039
|
Human |
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.039
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.039
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.039
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.039
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.038
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.038
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.038
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.037
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.037
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.037
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.037
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.037
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.036
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.036
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.036
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.036
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.036
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.035
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.035
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.035
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.035
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.035
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.034
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.034
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.034
|
Mouse |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.034
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.034
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.033
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.033
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.033
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.033
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.032
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.032
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.032
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.032
|
Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.031
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.031
|
|
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.031
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.031
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.030
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.030
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.030
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.030
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.030
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.030
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.030
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.030
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.029
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.029
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.029
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.029
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.029
|
|
|
|
ruffle organization
|
GO:0031529 |
18 |
0.029
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.029
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.029
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.028
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.028
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.028
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.028
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.028
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.028
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.028
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.028
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.027
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.027
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.027
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.027
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.027
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.027
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.027
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.027
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.026
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.026
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.026
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.026
|
Mouse |
|
|
regionalization
|
GO:0003002 |
29 |
0.026
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.026
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.026
|
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.026
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.026
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.026
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.026
|
Human |
|
|
head development
|
GO:0060322 |
108 |
0.025
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.025
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.025
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.025
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.025
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.025
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.025
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.024
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.024
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.024
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.024
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.024
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.024
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.024
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.024
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.024
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.024
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.024
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.024
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.024
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.023
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.023
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.023
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.023
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.023
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.023
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.023
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.023
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.023
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.023
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.023
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.023
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.023
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.022
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.022
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.022
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.022
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.022
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.022
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.022
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.022
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.022
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.022
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.022
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.022
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.022
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.021
|
Mouse |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.021
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.021
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.021
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.021
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.021
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.021
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.021
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.021
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.021
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.021
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.021
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.021
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.021
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.021
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.021
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.021
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.021
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.021
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.020
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
9 |
0.020
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.020
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.020
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.020
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.020
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.020
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.020
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.020
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.019
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.019
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.019
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.019
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.019
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.019
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.019
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.019
|
|
|
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.019
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.018
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.018
|
|
|
|
regulation of epithelial cell differentiation involved in kidney development
|
GO:2000696 |
4 |
0.018
|
|
|
|
cellular response to parathyroid hormone stimulus
|
GO:0071374 |
2 |
0.018
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.018
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.018
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.018
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.018
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.018
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.018
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.018
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.018
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.018
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.018
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.018
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.018
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.018
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.018
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.018
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.018
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.017
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.017
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.017
|
|
|
|
response to parathyroid hormone
|
GO:0071107 |
3 |
0.017
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.017
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.017
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.017
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.017
|
|
|
|
cortical cytoskeleton organization
|
GO:0030865 |
9 |
0.017
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.017
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.016
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.016
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.016
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.016
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.016
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.016
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.016
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.016
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.016
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.016
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.016
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.016
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.016
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.016
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.016
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.016
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.016
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.016
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.016
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.016
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.016
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.016
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.016
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.015
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.015
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.015
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.015
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.015
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.015
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.015
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.015
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.015
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.015
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.015
|
|
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.015
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.015
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.015
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.015
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.015
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.015
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.015
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.014
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
3 |
0.014
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.014
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.014
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.014
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.014
|
|
|
|
negative regulation of protein polymerization
|
GO:0032272 |
16 |
0.014
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.014
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
1 |
0.014
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.014
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.014
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.014
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.014
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.014
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.014
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.014
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.014
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.014
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.014
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.014
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.014
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.014
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.014
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.014
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.014
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.014
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.014
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.013
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.013
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.013
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.013
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.013
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.013
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.013
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.013
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.013
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.013
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.013
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.013
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.013
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.013
|
|
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.013
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.013
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.013
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.013
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.013
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.013
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.013
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.013
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.013
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.012
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.012
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.012
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.012
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.012
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.012
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.012
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.012
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.012
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.012
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.012
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.012
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.012
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.012
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.012
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.012
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.012
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.012
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.012
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.012
|
|
|
|
tube formation
|
GO:0035148 |
10 |
0.012
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.012
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.012
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.012
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.012
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.012
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.012
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.012
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.012
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.012
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.012
|
Mouse |
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.012
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.012
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.012
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.012
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.011
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.011
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.011
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.011
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.011
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.011
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.011
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.011
|
|
|
|
mating
|
GO:0007618 |
1 |
0.011
|
|
|
|
toxin transport
|
GO:1901998 |
4 |
0.011
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.011
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.011
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.011
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.011
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.011
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.011
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.011
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.011
|
|
|
|
toxin metabolic process
|
GO:0009404 |
4 |
0.011
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.011
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.011
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.011
|
|
