Homo sapiens

30 known processes

HECTD3

HECT domain containing 3

(Aliases: RP11-69J16.1,FLJ31983,MGC161630,FLJ21156)

HECTD3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 381 0.158
cellular lipid metabolic process GO:0044255 303 0.147
regulation of anatomical structure morphogenesis GO:0022603 286 0.123
cellular component morphogenesis GO:0032989 314 0.096
biological adhesion GO:0022610 331 0.083
cell substrate adhesion GO:0031589 132 0.074
cell development GO:0048468 328 0.071
cell matrix adhesion GO:0007160 85 0.069
nitrogen compound transport GO:0071705 191 0.068
purine nucleotide catabolic process GO:0006195 405 0.066
amine metabolic process GO:0009308 44 0.064
purine ribonucleotide catabolic process GO:0009154 404 0.064
membrane organization GO:0061024 292 0.061
glycosyl compound catabolic process GO:1901658 413 0.060
locomotory behavior GO:0007626 1 0.057
cell morphogenesis involved in differentiation GO:0000904 144 0.054
small gtpase mediated signal transduction GO:0007264 78 0.054
single organism cell adhesion GO:0098602 179 0.053
cell morphogenesis GO:0000902 296 0.051
regulation of cell differentiation GO:0045595 393 0.050
regulation of cellular ketone metabolic process GO:0010565 50 0.050
single organism cellular localization GO:1902580 332 0.049
endomembrane system organization GO:0010256 196 0.047
positive regulation of hydrolase activity GO:0051345 331 0.047
protein localization to organelle GO:0033365 280 0.047
lipid biosynthetic process GO:0008610 177 0.046
purine nucleoside catabolic process GO:0006152 398 0.046
system process GO:0003008 349 0.046
regulation of ras protein signal transduction GO:0046578 155 0.044
ribonucleotide catabolic process GO:0009261 405 0.044
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
positive regulation of gtpase activity GO:0043547 166 0.041
multi organism cellular process GO:0044764 156 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
purine nucleoside triphosphate catabolic process GO:0009146 392 0.039
cell projection organization GO:0030030 252 0.039
intracellular protein transport GO:0006886 270 0.039
cytoplasmic transport GO:0016482 379 0.039
cellular amine metabolic process GO:0044106 41 0.039
regulation of nucleoside metabolic process GO:0009118 209 0.037
oxidation reduction process GO:0055114 396 0.036
positive regulation of transport GO:0051050 336 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.036
rho protein signal transduction GO:0007266 26 0.036
organophosphate catabolic process GO:0046434 430 0.034
nucleoside triphosphate catabolic process GO:0009143 394 0.034
ras protein signal transduction GO:0007265 73 0.034
monocarboxylic acid metabolic process GO:0032787 185 0.034
guanosine containing compound metabolic process GO:1901068 244 0.033
actin filament based process GO:0030029 224 0.033
positive regulation of developmental process GO:0051094 314 0.033
actin cytoskeleton organization GO:0030036 207 0.032
nucleotide catabolic process GO:0009166 408 0.032
protein targeting GO:0006605 187 0.032
ribonucleoside catabolic process GO:0042454 406 0.032
regulation of proteolysis GO:0030162 293 0.032
positive regulation of ras gtpase activity GO:0032320 117 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.032
positive regulation of cell differentiation GO:0045597 211 0.032
cellular amino acid metabolic process GO:0006520 116 0.032
positive regulation of cellular component organization GO:0051130 376 0.031
purine containing compound catabolic process GO:0072523 411 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
neuromuscular junction development GO:0007528 3 0.031
nucleocytoplasmic transport GO:0006913 176 0.031
maintenance of location GO:0051235 112 0.030
gtp catabolic process GO:0006184 237 0.030
cell adhesion GO:0007155 325 0.030
anion transport GO:0006820 161 0.029
cellular ketone metabolic process GO:0042180 80 0.029
single organism carbohydrate metabolic process GO:0044723 193 0.029
post embryonic development GO:0009791 2 0.029
regulation of cell morphogenesis GO:0022604 153 0.029
female gamete generation GO:0007292 2 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
regulation of purine nucleotide catabolic process GO:0033121 205 0.029
compound eye development GO:0048749 1 0.028
regulation of cell adhesion GO:0030155 166 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
vesicle mediated transport GO:0016192 371 0.028
regulation of cell development GO:0060284 161 0.028
small molecule biosynthetic process GO:0044283 157 0.028
organic acid biosynthetic process GO:0016053 97 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.027
positive regulation of catabolic process GO:0009896 310 0.026
secretion by cell GO:0032940 226 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
cytokine production GO:0001816 247 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
morphogenesis of a polarized epithelium GO:0001738 3 0.026
regulation of protein localization GO:0032880 296 0.026
cellular protein complex assembly GO:0043623 188 0.025
gtp metabolic process GO:0046039 239 0.025
interspecies interaction between organisms GO:0044419 156 0.025
nucleoside catabolic process GO:0009164 408 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
secretion GO:0046903 254 0.025
regulation of cellular response to stress GO:0080135 244 0.025
regulation of cellular component biogenesis GO:0044087 281 0.025
positive regulation of gtp catabolic process GO:0033126 166 0.024
nuclear transport GO:0051169 179 0.024
neurological system process GO:0050877 163 0.024
fatty acid biosynthetic process GO:0006633 46 0.024
response to abiotic stimulus GO:0009628 336 0.024
cytokine mediated signaling pathway GO:0019221 109 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.024
multicellular organismal aging GO:0010259 3 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
monocarboxylic acid biosynthetic process GO:0072330 67 0.023
positive regulation of protein transport GO:0051222 135 0.023
viral process GO:0016032 146 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.023
alcohol metabolic process GO:0006066 114 0.023
viral life cycle GO:0019058 132 0.023
nervous system development GO:0007399 293 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
regulation of cell substrate adhesion GO:0010810 68 0.022
positive regulation of cell adhesion GO:0045785 84 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.021
segmentation GO:0035282 4 0.021
determination of adult lifespan GO:0008340 2 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
dephosphorylation GO:0016311 209 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
negative regulation of organelle organization GO:0010639 126 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
regulation of intracellular transport GO:0032386 195 0.020
regulation of multi organism process GO:0043900 157 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
negative regulation of developmental process GO:0051093 247 0.020
positive regulation of cytokine production GO:0001819 167 0.019
defense response GO:0006952 315 0.019
nucleus localization GO:0051647 1 0.019
protein maturation GO:0051604 233 0.019
positive regulation of neural precursor cell proliferation GO:2000179 2 0.019
protein processing GO:0016485 226 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
regulation of response to external stimulus GO:0032101 222 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
single organism nuclear import GO:1902593 104 0.019
negative regulation of protein metabolic process GO:0051248 391 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
histone modification GO:0016570 251 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
regulation of viral process GO:0050792 103 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
single organism membrane fusion GO:0044801 37 0.018
spermatid differentiation GO:0048515 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
response to organonitrogen compound GO:0010243 156 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
cellular protein catabolic process GO:0044257 261 0.018
positive regulation of cell substrate adhesion GO:0010811 37 0.018
regulation of defense response GO:0031347 154 0.017
regulation of locomotion GO:0040012 329 0.017
peripheral nervous system development GO:0007422 2 0.017
sensory perception of smell GO:0007608 2 0.017
cell part morphogenesis GO:0032990 137 0.017
angiogenesis GO:0001525 147 0.017
protein oligomerization GO:0051259 173 0.017
chromatin organization GO:0006325 351 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
endocytosis GO:0006897 159 0.017
organelle fusion GO:0048284 36 0.017
circulatory system development GO:0072359 262 0.017
lipid localization GO:0010876 106 0.017
response to nitrogen compound GO:1901698 184 0.016
protein import GO:0017038 130 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
growth GO:0040007 202 0.016
somitogenesis GO:0001756 2 0.016
glycerolipid metabolic process GO:0046486 107 0.016
neurogenesis GO:0022008 169 0.016
immune response GO:0006955 307 0.016
carbohydrate metabolic process GO:0005975 207 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.016
regulation of cytokine production GO:0001817 232 0.016
response to other organism GO:0051707 261 0.016
transmembrane transport GO:0055085 399 0.016
spermatid development GO:0007286 4 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
somatic muscle development GO:0007525 1 0.016
regulation of gtpase activity GO:0043087 180 0.016
organic anion transport GO:0015711 103 0.016
regulation of cellular component movement GO:0051270 334 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.016
protein localization to nucleus GO:0034504 136 0.016
cation transport GO:0006812 331 0.016
regulation of body fluid levels GO:0050878 99 0.016
adult locomotory behavior GO:0008344 1 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
positive regulation of cell development GO:0010720 92 0.015
cell cell junction organization GO:0045216 69 0.015
endosomal transport GO:0016197 129 0.015
regulation of protein transport GO:0051223 213 0.015
cofactor metabolic process GO:0051186 87 0.015
protein targeting to nucleus GO:0044744 104 0.015
peroxisome organization GO:0007031 28 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
positive regulation of synaptic transmission GO:0050806 4 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
response to cytokine GO:0034097 232 0.015
response to biotic stimulus GO:0009607 276 0.015
protein import into nucleus GO:0006606 104 0.015
blood vessel development GO:0001568 172 0.015
positive regulation of rab gtpase activity GO:0032851 39 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
single organism membrane organization GO:0044802 268 0.015
memory GO:0007613 3 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
neuron projection development GO:0031175 106 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
oogenesis GO:0048477 2 0.014
cardiovascular system development GO:0072358 262 0.014
response to oxygen containing compound GO:1901700 369 0.014
organelle assembly GO:0070925 176 0.014
protein dephosphorylation GO:0006470 81 0.014
regulation of secretion GO:0051046 194 0.014
positive regulation of rho gtpase activity GO:0032321 56 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
carboxylic acid transport GO:0046942 63 0.014
regulation of cell cycle GO:0051726 393 0.014
fatty acid metabolic process GO:0006631 115 0.014
activation of immune response GO:0002253 114 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
regulation of immune response GO:0050776 201 0.014
substrate adhesion dependent cell spreading GO:0034446 41 0.014
positive regulation of immune system process GO:0002684 283 0.014
cell projection morphogenesis GO:0048858 129 0.014
developmental programmed cell death GO:0010623 3 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
chemotaxis GO:0006935 157 0.014
nuclear import GO:0051170 106 0.014
blood vessel morphogenesis GO:0048514 162 0.014
rhythmic behavior GO:0007622 2 0.014
regulation of endopeptidase activity GO:0052548 170 0.013
cation transmembrane transport GO:0098655 238 0.013
taxis GO:0042330 157 0.013
mitochondrion organization GO:0007005 156 0.013
chemical homeostasis GO:0048878 306 0.013
regulation of secretion by cell GO:1903530 177 0.013
neuron differentiation GO:0030182 138 0.013
negative regulation of multi organism process GO:0043901 92 0.013
macromolecule glycosylation GO:0043413 63 0.013
response to hormone GO:0009725 175 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
wnt signaling pathway GO:0016055 156 0.013
immune system development GO:0002520 195 0.013
regulation of cell cycle process GO:0010564 266 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of immune effector process GO:0002697 91 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
interleukin 8 production GO:0032637 51 0.013
nerve development GO:0021675 4 0.013
amino acid transport GO:0006865 28 0.013
pattern recognition receptor signaling pathway GO:0002221 48 0.013
negative regulation of protein modification process GO:0031400 200 0.013
protein methylation GO:0006479 74 0.013
positive regulation of interleukin 8 production GO:0032757 36 0.013
blastoderm segmentation GO:0007350 2 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
neuron development GO:0048666 113 0.013
positive regulation of cytoplasmic transport GO:1903651 82 0.013
tube closure GO:0060606 3 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
regulation of protein complex assembly GO:0043254 147 0.013
phospholipid metabolic process GO:0006644 99 0.013
response to virus GO:0009615 126 0.013
central nervous system development GO:0007417 123 0.013
apoptotic signaling pathway GO:0097190 268 0.012
protein catabolic process GO:0030163 325 0.012
ameboidal type cell migration GO:0001667 135 0.012
ion transmembrane transport GO:0034220 338 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
cation homeostasis GO:0055080 189 0.012
regeneration GO:0031099 4 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
visual behavior GO:0007632 2 0.012
nuclear migration GO:0007097 1 0.012
positive regulation of secretion GO:0051047 116 0.012
regulation of mitochondrion organization GO:0010821 54 0.012
cell substrate junction assembly GO:0007044 35 0.012
actin filament based movement GO:0030048 17 0.012
neurotransmitter secretion GO:0007269 4 0.012
innate immune response GO:0045087 178 0.012
negative regulation of cell death GO:0060548 345 0.012
response to fungus GO:0009620 4 0.012
brain morphogenesis GO:0048854 1 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
regulation of hydrogen peroxide mediated programmed cell death GO:1901298 4 0.012
atp metabolic process GO:0046034 176 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
establishment of tissue polarity GO:0007164 3 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
golgi organization GO:0007030 38 0.012
epithelium development GO:0060429 227 0.012
autophagy GO:0006914 88 0.012
regulation of response to cytokine stimulus GO:0060759 46 0.012
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.012
regulation of kinase activity GO:0043549 314 0.012
regulation of protein localization to nucleus GO:1900180 85 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
steroid metabolic process GO:0008202 94 0.011
response to extracellular stimulus GO:0009991 85 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
circadian behavior GO:0048512 2 0.011
lipid transport GO:0006869 90 0.011
protein homooligomerization GO:0051260 100 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
oocyte differentiation GO:0009994 2 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
regulation of mapk cascade GO:0043408 262 0.011
macromolecule methylation GO:0043414 97 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
regulation of ion transport GO:0043269 189 0.011
cell junction assembly GO:0034329 67 0.011
positive regulation of kinase activity GO:0033674 204 0.011
regulation of transferase activity GO:0051338 355 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
meiotic chromosome segregation GO:0045132 4 0.011
tube development GO:0035295 125 0.011
organic acid transport GO:0015849 65 0.011
response to oxygen levels GO:0070482 100 0.011
establishment of nucleus localization GO:0040023 1 0.011
neural tube formation GO:0001841 3 0.011
regulation of viral genome replication GO:0045069 48 0.011
cellular homeostasis GO:0019725 196 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
cell type specific apoptotic process GO:0097285 125 0.011
vacuole organization GO:0007033 44 0.010
establishment of planar polarity GO:0001736 3 0.010
response to organic cyclic compound GO:0014070 204 0.010
head development GO:0060322 108 0.010
regulation of protein maturation GO:1903317 150 0.010
t cell differentiation in thymus GO:0033077 4 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
response to external biotic stimulus GO:0043207 261 0.010
sensory perception GO:0007600 103 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
protein ubiquitination GO:0016567 314 0.010
positive regulation of mapk cascade GO:0043410 190 0.010
cellular chemical homeostasis GO:0055082 180 0.010
membrane lipid metabolic process GO:0006643 53 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
neural tube closure GO:0001843 3 0.010
axis elongation GO:0003401 4 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
regulation of peptidyl serine phosphorylation GO:0033135 50 0.010
regulation of protein kinase activity GO:0045859 289 0.010
ion homeostasis GO:0050801 230 0.010
regulation of dna metabolic process GO:0051052 153 0.010
microtubule based process GO:0007017 210 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
positive regulation of dendrite morphogenesis GO:0050775 3 0.010

HECTD3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.119
nervous system disease DOID:863 431 0.119
sensory system disease DOID:0050155 203 0.073
auditory system disease DOID:2742 53 0.036
nonsyndromic deafness DOID:0050563 50 0.029
autosomal recessive nonsyndromic deafness DOID:0050565 33 0.025
brain disease DOID:936 73 0.018
neurodegenerative disease DOID:1289 102 0.017
disease of metabolism DOID:0014667 295 0.014
epilepsy syndrome DOID:1826 41 0.014
electroclinical syndrome DOID:0050701 32 0.014
neonatal period electroclinical syndrome DOID:0050702 19 0.014
musculoskeletal system disease DOID:17 223 0.014
cardiovascular system disease DOID:1287 106 0.013
inherited metabolic disorder DOID:655 242 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
retinal disease DOID:5679 118 0.011
retinal degeneration DOID:8466 89 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
parkinson s disease DOID:14330 18 0.011
synucleinopathy DOID:0050890 22 0.011
myopathy DOID:423 104 0.010