Homo sapiens

0 known processes

NUF2

NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)

(Aliases: CDCA1,CT106,NUF2R)

NUF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
maintenance of location in cell GO:0051651 62 0.688
attachment of spindle microtubules to kinetochore GO:0008608 17 0.673
microtubule anchoring GO:0034453 24 0.646
maintenance of location GO:0051235 112 0.633
microtubule cytoskeleton organization GO:0000226 176 0.542
chromosome segregation GO:0007059 114 0.518
organelle fission GO:0048285 149 0.495
maintenance of protein location GO:0045185 57 0.437
nuclear division GO:0000280 128 0.434
mitotic nuclear division GO:0007067 119 0.345
microtubule based process GO:0007017 210 0.296
mitotic cell cycle process GO:1903047 286 0.289
mitotic cell cycle GO:0000278 326 0.279
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.274
protein localization to chromosome centromeric region GO:0071459 12 0.274
maintenance of protein location in cell GO:0032507 56 0.265
sister chromatid segregation GO:0000819 54 0.260
regulation of cell cycle GO:0051726 393 0.247
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.220
spindle assembly checkpoint GO:0071173 17 0.214
cell cycle phase transition GO:0044770 173 0.177
positive regulation of cellular catabolic process GO:0031331 284 0.155
protein depolymerization GO:0051261 30 0.153
mitotic spindle organization GO:0007052 27 0.144
protein localization to organelle GO:0033365 280 0.140
nucleoside triphosphate metabolic process GO:0009141 422 0.140
organelle assembly GO:0070925 176 0.135
mitotic sister chromatid segregation GO:0000070 53 0.133
protein localization to kinetochore GO:0034501 10 0.116
cell cycle checkpoint GO:0000075 117 0.116
spindle organization GO:0007051 53 0.105
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.104
intrinsic apoptotic signaling pathway GO:0097193 127 0.104
positive regulation of protein phosphorylation GO:0001934 313 0.104
regulation of apoptotic signaling pathway GO:2001233 175 0.100
regulation of cell cycle process GO:0010564 266 0.094
regulation of protein catabolic process GO:0042176 155 0.088
mitotic spindle assembly checkpoint GO:0007094 14 0.084
positive regulation of cellular component organization GO:0051130 376 0.081
regulation of locomotion GO:0040012 329 0.078
regulation of cell cycle phase transition GO:1901987 126 0.075
regulation of cell migration GO:0030334 289 0.075
protein maturation GO:0051604 233 0.072
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.072
positive regulation of phosphorylation GO:0042327 394 0.068
cellular macromolecule catabolic process GO:0044265 380 0.067
protein processing GO:0016485 226 0.066
negative regulation of protein processing GO:0010955 142 0.066
growth GO:0040007 202 0.064
negative regulation of cell cycle GO:0045786 193 0.063
regulation of mitotic sister chromatid segregation GO:0033047 27 0.060
mitotic spindle midzone assembly GO:0051256 4 0.059
regulation of mitotic cell cycle GO:0007346 189 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.057
positive regulation of transferase activity GO:0051347 227 0.052
purine nucleoside triphosphate catabolic process GO:0009146 392 0.048
regulation of protein localization GO:0032880 296 0.048
cellular macromolecular complex assembly GO:0034622 324 0.047
positive regulation of catabolic process GO:0009896 310 0.047
regulation of proteolysis GO:0030162 293 0.046
regulation of sister chromatid cohesion GO:0007063 9 0.046
centromeric sister chromatid cohesion GO:0070601 3 0.045
mitotic cell cycle checkpoint GO:0007093 68 0.045
purine ribonucleoside catabolic process GO:0046130 398 0.044
cell division GO:0051301 168 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
regulation of cellular component movement GO:0051270 334 0.044
nucleoside phosphate catabolic process GO:1901292 412 0.043
mitotic sister chromatid separation GO:0051306 18 0.043
positive regulation of cytoskeleton organization GO:0051495 83 0.042
negative regulation of protein catabolic process GO:0042177 59 0.041
regulation of microtubule cytoskeleton organization GO:0070507 61 0.041
establishment of organelle localization GO:0051656 59 0.041
regulation of cytoskeleton organization GO:0051493 177 0.041
negative regulation of cell death GO:0060548 345 0.041
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.040
modification dependent protein catabolic process GO:0019941 209 0.040
cellular response to endogenous stimulus GO:0071495 336 0.039
regulation of microtubule based process GO:0032886 74 0.038
negative regulation of proteolysis GO:0045861 132 0.038
regulation of transferase activity GO:0051338 355 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.037
metaphase plate congression GO:0051310 18 0.036
regulation of mitotic cell cycle phase transition GO:1901990 118 0.036
positive regulation of apoptotic process GO:0043065 246 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.034
regulation of protein processing GO:0070613 150 0.034
negative regulation of cell cycle phase transition GO:1901988 89 0.034
positive regulation of proteolysis GO:0045862 142 0.034
positive regulation of protein kinase activity GO:0045860 190 0.033
positive regulation of kinase activity GO:0033674 204 0.033
positive regulation of organelle organization GO:0010638 195 0.032
negative regulation of cellular component organization GO:0051129 235 0.032
somatic muscle development GO:0007525 1 0.032
cellular protein catabolic process GO:0044257 261 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.032
vesicle mediated transport GO:0016192 371 0.032
post embryonic development GO:0009791 2 0.031
endomembrane system organization GO:0010256 196 0.031
proteasomal protein catabolic process GO:0010498 176 0.031
purine nucleotide catabolic process GO:0006195 405 0.031
regulation of cell motility GO:2000145 299 0.031
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.031
single organism cellular localization GO:1902580 332 0.030
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.030
actin filament based process GO:0030029 224 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.029
regulation of protein maturation GO:1903317 150 0.028
response to abiotic stimulus GO:0009628 336 0.028
negative regulation of organelle organization GO:0010639 126 0.027
protein localization to chromosome GO:0034502 30 0.027
protein catabolic process GO:0030163 325 0.027
negative regulation of catabolic process GO:0009895 104 0.026
sister chromatid cohesion GO:0007062 24 0.026
response to radiation GO:0009314 151 0.026
spindle assembly involved in mitosis GO:0090307 12 0.026
apoptotic signaling pathway GO:0097190 268 0.026
negative regulation of programmed cell death GO:0043069 321 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
innate immune response GO:0045087 178 0.025
cellular protein complex assembly GO:0043623 188 0.025
regulation of cell division GO:0051302 116 0.025
cytoplasmic transport GO:0016482 379 0.024
negative regulation of mitotic cell cycle GO:0045930 102 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.024
nucleoside monophosphate catabolic process GO:0009125 159 0.024
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.024
actin cytoskeleton organization GO:0030036 207 0.023
regulation of kinase activity GO:0043549 314 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
organ morphogenesis GO:0009887 147 0.022
histone modification GO:0016570 251 0.022
reproductive system development GO:0061458 56 0.022
negative regulation of cellular protein catabolic process GO:1903363 38 0.022
protein secretion GO:0009306 98 0.022
hemopoiesis GO:0030097 180 0.022
spindle midzone assembly GO:0051255 4 0.021
immune response GO:0006955 307 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
positive regulation of mitotic metaphase anaphase transition GO:0045842 6 0.021
regulation of protein kinase activity GO:0045859 289 0.021
secretion GO:0046903 254 0.021
mitotic spindle elongation GO:0000022 4 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.019
single organism membrane organization GO:0044802 268 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
mitotic centrosome separation GO:0007100 1 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
secretion by cell GO:0032940 226 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
regulation of chromosome organization GO:0033044 103 0.018
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.018
negative regulation of multicellular organismal process GO:0051241 317 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
reproduction GO:0000003 63 0.017
neurogenesis GO:0022008 169 0.017
ribonucleoside monophosphate catabolic process GO:0009158 158 0.017
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.017
negative regulation of chromosome segregation GO:0051985 18 0.017
protein dna complex subunit organization GO:0071824 80 0.017
blastocyst development GO:0001824 3 0.017
negative regulation of protein maturation GO:1903318 142 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
positive regulation of protein catabolic process GO:0045732 75 0.017
positive regulation of apoptotic signaling pathway GO:2001235 70 0.017
organelle localization GO:0051640 84 0.017
response to uv GO:0009411 73 0.016
negative regulation of sister chromatid segregation GO:0033046 17 0.016
reproductive process GO:0022414 106 0.016
mitotic spindle checkpoint GO:0071174 18 0.016
nervous system development GO:0007399 293 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
centrosome duplication GO:0051298 28 0.016
positive regulation of transport GO:0051050 336 0.016
organophosphate catabolic process GO:0046434 430 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.016
mitotic metaphase plate congression GO:0007080 14 0.015
oogenesis GO:0048477 2 0.015
cell projection organization GO:0030030 252 0.015
cellular response to radiation GO:0071478 65 0.015
epithelium development GO:0060429 227 0.015
developmental process involved in reproduction GO:0003006 66 0.015
spindle checkpoint GO:0031577 26 0.015
regulation of cell differentiation GO:0045595 393 0.015
establishment or maintenance of cell polarity GO:0007163 31 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.014
establishment of chromosome localization GO:0051303 20 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
neuroblast proliferation GO:0007405 4 0.014
wnt signaling pathway GO:0016055 156 0.014
regulation of chromosome segregation GO:0051983 44 0.014
negative regulation of chromosome organization GO:2001251 48 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
defense response GO:0006952 315 0.014
microtubule based movement GO:0007018 32 0.014
spindle elongation GO:0051231 4 0.014
positive regulation of wnt signaling pathway GO:0030177 54 0.013
intracellular protein transport GO:0006886 270 0.013
epithelial cell differentiation GO:0030855 141 0.013
single organism reproductive process GO:0044702 98 0.013
cellular amine metabolic process GO:0044106 41 0.013
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.013
actin filament based movement GO:0030048 17 0.013
somatic stem cell division GO:0048103 1 0.013
cellular ketone metabolic process GO:0042180 80 0.013
regulation of protein transport GO:0051223 213 0.013
embryo development GO:0009790 123 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
positive regulation of cell death GO:0010942 263 0.012
protein polymerization GO:0051258 71 0.012
negative regulation of cytoskeleton organization GO:0051494 45 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
negative regulation of cell division GO:0051782 31 0.012
cellular response to abiotic stimulus GO:0071214 117 0.011
endocytosis GO:0006897 159 0.011
cell morphogenesis GO:0000902 296 0.011
protein complex disassembly GO:0043241 52 0.011
regulation of mitosis GO:0007088 63 0.011
cellular component morphogenesis GO:0032989 314 0.011
positive regulation of cellular protein catabolic process GO:1903364 37 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
atp catabolic process GO:0006200 157 0.011
regulation of cell growth GO:0001558 135 0.011
cell growth GO:0016049 160 0.011
cardiovascular system development GO:0072358 262 0.011
Zebrafish
protein dna complex assembly GO:0065004 64 0.011
establishment of mitotic spindle orientation GO:0000132 7 0.011
negative regulation of immune system process GO:0002683 136 0.011
response to wounding GO:0009611 168 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 6 0.010
chromosome separation GO:0051304 23 0.010
cellular amino acid metabolic process GO:0006520 116 0.010
osteoblast differentiation GO:0001649 92 0.010

NUF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.123
congenital nervous system abnormality DOID:2490 21 0.123
disease of cellular proliferation DOID:14566 174 0.073
cancer DOID:162 167 0.042
organ system cancer DOID:0050686 164 0.042