Homo sapiens

6 known processes

COG5

component of oligomeric golgi complex 5

(Aliases: GOLTC1,CDG2I,FLJ41732,FLJ44289,GTC90)

COG5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic transport GO:0016482 379 0.454
golgi vesicle transport GO:0048193 80 0.369
protein localization to organelle GO:0033365 280 0.342
intracellular protein transport GO:0006886 270 0.294
vesicle mediated transport GO:0016192 371 0.237
gtp catabolic process GO:0006184 237 0.220
single organism cellular localization GO:1902580 332 0.208
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.179
nucleoside catabolic process GO:0009164 408 0.162
ribonucleotide catabolic process GO:0009261 405 0.158
nucleoside triphosphate metabolic process GO:0009141 422 0.156
establishment of protein localization to organelle GO:0072594 172 0.137
purine ribonucleoside catabolic process GO:0046130 398 0.133
carbohydrate metabolic process GO:0005975 207 0.130
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.123
organophosphate catabolic process GO:0046434 430 0.123
guanosine containing compound catabolic process GO:1901069 239 0.109
purine nucleoside catabolic process GO:0006152 398 0.108
ribonucleoside catabolic process GO:0042454 406 0.107
purine nucleoside triphosphate metabolic process GO:0009144 412 0.103
ribonucleoside triphosphate catabolic process GO:0009203 391 0.103
positive regulation of hydrolase activity GO:0051345 331 0.100
membrane organization GO:0061024 292 0.093
glycosyl compound catabolic process GO:1901658 413 0.089
nucleotide catabolic process GO:0009166 408 0.086
purine ribonucleotide catabolic process GO:0009154 404 0.083
post embryonic development GO:0009791 2 0.082
purine ribonucleoside metabolic process GO:0046128 437 0.081
purine nucleotide catabolic process GO:0006195 405 0.081
protein targeting GO:0006605 187 0.080
single organism carbohydrate metabolic process GO:0044723 193 0.080
protein localization to plasma membrane GO:0072659 93 0.079
nucleoside triphosphate catabolic process GO:0009143 394 0.073
glycoprotein biosynthetic process GO:0009101 91 0.071
gtp metabolic process GO:0046039 239 0.058
ribonucleoside triphosphate metabolic process GO:0009199 412 0.056
single organism membrane fusion GO:0044801 37 0.055
purine containing compound catabolic process GO:0072523 411 0.055
negative regulation of catalytic activity GO:0043086 335 0.054
endocytosis GO:0006897 159 0.054
purine nucleoside triphosphate catabolic process GO:0009146 392 0.052
mitochondrion organization GO:0007005 156 0.051
embryonic epithelial tube formation GO:0001838 4 0.050
ras protein signal transduction GO:0007265 73 0.050
nucleoside phosphate catabolic process GO:1901292 412 0.049
endomembrane system organization GO:0010256 196 0.048
positive regulation of nucleotide metabolic process GO:0045981 230 0.048
regulation of nucleotide metabolic process GO:0006140 269 0.048
morphogenesis of embryonic epithelium GO:0016331 4 0.047
regulation of nucleoside metabolic process GO:0009118 209 0.047
establishment of protein localization to membrane GO:0090150 121 0.047
atp metabolic process GO:0046034 176 0.046
rho protein signal transduction GO:0007266 26 0.046
oogenesis GO:0048477 2 0.045
regulation of intracellular transport GO:0032386 195 0.044
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.042
cellular amino acid metabolic process GO:0006520 116 0.042
guanosine containing compound metabolic process GO:1901068 244 0.042
regulation of purine nucleotide catabolic process GO:0033121 205 0.042
positive regulation of nucleoside metabolic process GO:0045979 186 0.042
single organism membrane organization GO:0044802 268 0.041
positive regulation of nucleotide catabolic process GO:0030813 185 0.040
regulation of protein transport GO:0051223 213 0.039
small gtpase mediated signal transduction GO:0007264 78 0.038
er to golgi vesicle mediated transport GO:0006888 19 0.038
post golgi vesicle mediated transport GO:0006892 36 0.038
negative regulation of phosphorus metabolic process GO:0010563 267 0.037
positive regulation of transport GO:0051050 336 0.037
positive regulation of catabolic process GO:0009896 310 0.036
glycosylation GO:0070085 71 0.035
positive regulation of cellular component organization GO:0051130 376 0.034
regulation of cytoplasmic transport GO:1903649 149 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.033
regulation of cell motility GO:2000145 299 0.033
protein localization to membrane GO:0072657 160 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.032
cellular homeostasis GO:0019725 196 0.031
positive regulation of gtpase activity GO:0043547 166 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
retrograde transport endosome to golgi GO:0042147 45 0.031
macromolecule glycosylation GO:0043413 63 0.031
positive regulation of cellular catabolic process GO:0031331 284 0.031
glycoprotein metabolic process GO:0009100 110 0.031
regulation of protein localization GO:0032880 296 0.030
innate immune response GO:0045087 178 0.030
negative regulation of organelle organization GO:0010639 126 0.029
regulation of nucleotide catabolic process GO:0030811 205 0.029
establishment of protein localization to plasma membrane GO:0090002 68 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
golgi organization GO:0007030 38 0.029
hindbrain development GO:0030902 3 0.029
endoplasmic reticulum organization GO:0007029 20 0.028
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
regulation of transferase activity GO:0051338 355 0.027
regulation of cellular component movement GO:0051270 334 0.027
oxidation reduction process GO:0055114 396 0.026
regulation of protein stability GO:0031647 87 0.026
female gamete generation GO:0007292 2 0.026
toxin metabolic process GO:0009404 4 0.026
immune response GO:0006955 307 0.026
retrograde vesicle mediated transport golgi to er GO:0006890 8 0.026
positive regulation of organelle organization GO:0010638 195 0.026
locomotory behavior GO:0007626 1 0.026
positive regulation of immune system process GO:0002684 283 0.026
regulation of cell migration GO:0030334 289 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
regulation of ras protein signal transduction GO:0046578 155 0.025
positive regulation of gtp catabolic process GO:0033126 166 0.025
apoptotic signaling pathway GO:0097190 268 0.024
protein maturation GO:0051604 233 0.024
lipid biosynthetic process GO:0008610 177 0.024
maintenance of location GO:0051235 112 0.024
actin filament based process GO:0030029 224 0.023
inner ear morphogenesis GO:0042472 4 0.023
cellular lipid metabolic process GO:0044255 303 0.023
regulation of intracellular protein transport GO:0033157 123 0.023
determination of adult lifespan GO:0008340 2 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
endosomal transport GO:0016197 129 0.022
spermatid differentiation GO:0048515 4 0.022
regulation of gtpase activity GO:0043087 180 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
cellular cation homeostasis GO:0030003 163 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
response to oxygen containing compound GO:1901700 369 0.022
spermatid development GO:0007286 4 0.022
protein targeting to peroxisome GO:0006625 15 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
neuromuscular junction development GO:0007528 3 0.021
regulation of cytoskeleton organization GO:0051493 177 0.021
purine nucleoside monophosphate metabolic process GO:0009126 186 0.021
negative regulation of cell death GO:0060548 345 0.021
nuclear transport GO:0051169 179 0.020
engulfment of apoptotic cell GO:0043652 2 0.020
regulation of vesicle mediated transport GO:0060627 130 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
ion transmembrane transport GO:0034220 338 0.020
neural tube formation GO:0001841 3 0.020
regulation of cell cycle GO:0051726 393 0.020
maintenance of cell polarity GO:0030011 2 0.020
nucleoside monophosphate metabolic process GO:0009123 191 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
regeneration GO:0031099 4 0.019
protein catabolic process GO:0030163 325 0.019
membrane fusion GO:0061025 43 0.019
organelle fusion GO:0048284 36 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
rhythmic behavior GO:0007622 2 0.019
defense response GO:0006952 315 0.019
anterior posterior axis specification GO:0009948 2 0.019
protein ubiquitination GO:0016567 314 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of immune response GO:0050776 201 0.018
plasma membrane organization GO:0007009 115 0.017
organelle localization GO:0051640 84 0.017
tripartite regional subdivision GO:0007351 2 0.017
cell adhesion GO:0007155 325 0.017
nucleoside monophosphate catabolic process GO:0009125 159 0.017
amine metabolic process GO:0009308 44 0.017
actin cytoskeleton organization GO:0030036 207 0.017
protein import into nucleus GO:0006606 104 0.016
multicellular organismal aging GO:0010259 3 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
response to lipid GO:0033993 206 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
biological adhesion GO:0022610 331 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
receptor mediated endocytosis GO:0006898 84 0.015
protein glycosylation GO:0006486 62 0.015
negative regulation of cell cycle GO:0045786 193 0.015
regulation of cell adhesion GO:0030155 166 0.015
positive regulation of immune response GO:0050778 159 0.015
vesicle organization GO:0016050 62 0.015
transmembrane transport GO:0055085 399 0.015
neural tube closure GO:0001843 3 0.015
mitochondrial transport GO:0006839 60 0.015
cell development GO:0048468 328 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
protein targeting to nucleus GO:0044744 104 0.014
protein localization to adherens junction GO:0071896 2 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
protein import GO:0017038 130 0.014
response to wounding GO:0009611 168 0.014
blastoderm segmentation GO:0007350 2 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
regulation of proteolysis GO:0030162 293 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
negative regulation of transport GO:0051051 176 0.014
regulation of protein complex assembly GO:0043254 147 0.014
protein localization to nucleus GO:0034504 136 0.014
vesicle fusion GO:0006906 17 0.014
segmentation GO:0035282 4 0.014
ion homeostasis GO:0050801 230 0.013
regulation of protein localization to nucleus GO:1900180 85 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
cellular component morphogenesis GO:0032989 314 0.013
positive regulation of ras gtpase activity GO:0032320 117 0.013
cation homeostasis GO:0055080 189 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
regulation of dna metabolic process GO:0051052 153 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
nervous system development GO:0007399 293 0.013
oocyte development GO:0048599 1 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
cation transmembrane transport GO:0098655 238 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
organ morphogenesis GO:0009887 147 0.013
positive regulation of cell cycle GO:0045787 140 0.013
oocyte differentiation GO:0009994 2 0.013
regulation of protein targeting GO:1903533 91 0.013
cellular ion homeostasis GO:0006873 168 0.013
positive regulation of transferase activity GO:0051347 227 0.013
mitotic cell cycle process GO:1903047 286 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
cellular ketone metabolic process GO:0042180 80 0.012
protein folding GO:0006457 38 0.012
cell morphogenesis GO:0000902 296 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
cell growth GO:0016049 160 0.012
establishment of protein localization to mitochondrion GO:0072655 22 0.012
lipid metabolic process GO:0006629 381 0.012
chemical homeostasis GO:0048878 306 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
regulation of membrane potential GO:0042391 95 0.012
establishment of planar polarity GO:0001736 3 0.012
anatomical structure homeostasis GO:0060249 100 0.012
nitrogen compound transport GO:0071705 191 0.012
response to inorganic substance GO:0010035 127 0.012
atp catabolic process GO:0006200 157 0.012
intra golgi vesicle mediated transport GO:0006891 8 0.012
sequestering of metal ion GO:0051238 24 0.012
cell projection organization GO:0030030 252 0.012
primary neural tube formation GO:0014020 3 0.012
mitochondrial membrane organization GO:0007006 40 0.012
protein processing GO:0016485 226 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
cellular protein complex assembly GO:0043623 188 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
microtubule based process GO:0007017 210 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
secretion by cell GO:0032940 226 0.011
tube closure GO:0060606 3 0.011
wound healing GO:0042060 115 0.011
regulation of protein catabolic process GO:0042176 155 0.011
cellular amine metabolic process GO:0044106 41 0.011
regulation of locomotion GO:0040012 329 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
compound eye development GO:0048749 1 0.011
response to virus GO:0009615 126 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
meiosis i GO:0007127 4 0.011
motor neuron axon guidance GO:0008045 2 0.011
metal ion homeostasis GO:0055065 169 0.011
response to external biotic stimulus GO:0043207 261 0.011
regulation of kinase activity GO:0043549 314 0.010
regulation of ion transport GO:0043269 189 0.010
anion transport GO:0006820 161 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
calcium ion homeostasis GO:0055074 122 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
divalent inorganic cation transport GO:0072511 158 0.010
regulation of protein import into nucleus GO:0042306 78 0.010
single organism nuclear import GO:1902593 104 0.010
regulation of cell cycle process GO:0010564 266 0.010
metal ion transport GO:0030001 272 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
response to biotic stimulus GO:0009607 276 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
metencephalon development GO:0022037 2 0.010
cellular divalent inorganic cation homeostasis GO:0072503 128 0.010

COG5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.076
musculoskeletal system disease DOID:17 223 0.036
central nervous system disease DOID:331 186 0.035
nervous system disease DOID:863 431 0.035
muscular disease DOID:0080000 114 0.025
muscle tissue disease DOID:66 113 0.020
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
organ system cancer DOID:0050686 164 0.016
carbohydrate metabolic disorder DOID:2978 55 0.015
congenital disorder of glycosylation DOID:5212 26 0.015
inherited metabolic disorder DOID:655 242 0.015
myopathy DOID:423 104 0.014
muscular dystrophy DOID:9884 51 0.014
immune system disease DOID:2914 155 0.013
brain disease DOID:936 73 0.011
congenital disorder of glycosylation type ii DOID:0050571 10 0.003