|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.424
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.205
|
Human Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.192
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.179
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.178
|
Fly |
|
|
visual learning
|
GO:0008542 |
1 |
0.157
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.130
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.125
|
Human Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.120
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.115
|
Human Mouse Worm Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.106
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.101
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.098
|
Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.089
|
Human Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.089
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.088
|
Worm Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.086
|
Human Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.083
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.081
|
Mouse Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.078
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.075
|
Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.073
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.072
|
Human |
|
|
visual behavior
|
GO:0007632 |
2 |
0.071
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.070
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.070
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.069
|
Worm Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.069
|
Mouse Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.069
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.069
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.068
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.064
|
Human Worm |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.064
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.064
|
Mouse Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.063
|
Human Mouse Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.063
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.062
|
Human Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.061
|
Mouse |
|
|
fear response
|
GO:0042596 |
0 |
0.061
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.059
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.059
|
Mouse Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.058
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.058
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.058
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.058
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.058
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.057
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.056
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.056
|
Mouse Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.055
|
Human |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.054
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.054
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.052
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.051
|
Human |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.051
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.051
|
Mouse Fly |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.049
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.049
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.049
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.049
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.049
|
Human Worm Fly |
|
|
tube closure
|
GO:0060606 |
3 |
0.049
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.048
|
Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.048
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.048
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.047
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.047
|
Human |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.046
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.046
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.046
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.045
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.045
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.044
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.044
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.043
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.043
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.043
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.043
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.043
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.043
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.043
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.042
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.042
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.042
|
Mouse Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.042
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.042
|
Human |
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.042
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.042
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.041
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.041
|
Human Fly |
|
|
heart formation
|
GO:0060914 |
2 |
0.041
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.041
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.041
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.041
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.040
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.040
|
Human Worm |
|
|
rna stabilization
|
GO:0043489 |
18 |
0.040
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.040
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.040
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.040
|
Mouse Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.039
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.039
|
Human |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.039
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.038
|
Worm |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.038
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.037
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.036
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.036
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.036
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.036
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.036
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.036
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.036
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.036
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.035
|
Human Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.035
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.034
|
Human |
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.034
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.034
|
Human |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.033
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.033
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.033
|
Mouse Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.033
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.032
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.032
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.032
|
Mouse Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.032
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.032
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.032
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.031
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.031
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.031
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.031
|
Human Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.031
|
Human |
|
|
heart field specification
|
GO:0003128 |
2 |
0.031
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.031
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.031
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.031
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.031
|
Fly |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.030
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.030
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.030
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.030
|
Worm |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.030
|
Human Fly |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.030
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.030
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.030
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.029
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.029
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.029
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.029
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.029
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.029
|
Human |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.029
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.028
|
Human Fly |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.028
|
Human |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.028
|
Mouse Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.028
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.027
|
Worm |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.027
|
Worm Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.027
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.027
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.027
|
Human |
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.027
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.026
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.026
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.026
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.026
|
Mouse |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.026
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.026
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.026
|
Human Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.026
|
Mouse Fly |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.025
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.025
|
Human Fly |
|
|
neural plate regionalization
|
GO:0060897 |
1 |
0.025
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.025
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.024
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.024
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.024
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.024
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.024
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.024
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.024
|
Human Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.023
|
Fly |
|
|
ossification
|
GO:0001503 |
121 |
0.023
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.023
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.023
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.023
|
Worm Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.023
|
Human Mouse |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.023
|
Fly |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.023
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.023
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.023
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.022
|
Fly |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.022
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.022
|
Fly |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.022
|
Human |
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.022
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.022
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.022
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.022
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.022
|
Human |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.022
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.022
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.022
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.022
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.022
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.022
|
Fly |
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.021
|
Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.021
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.021
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.021
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.021
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.021
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.021
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.021
|
Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.021
|
Human |
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.021
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.020
|
Human |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.020
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.020
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.020
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.020
|
Worm Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.020
|
|
|
|
memory
|
GO:0007613 |
3 |
0.020
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.020
|
Fly |
|
|
rna processing
|
GO:0006396 |
255 |
0.020
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.020
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.020
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.020
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.020
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.020
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.020
|
|
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.019
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.019
|
Mouse Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.019
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.019
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.019
|
Human Worm |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.019
|
Human |
|
|
long term memory
|
GO:0007616 |
2 |
0.019
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.019
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.018
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.018
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.018
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.018
|
Human |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.018
|
Mouse |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.018
|
Human |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.018
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.018
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.018
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.018
|
Mouse Worm |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.018
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.018
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.018
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.018
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.018
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.018
|
Human Mouse |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.018
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.018
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.018
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.018
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.018
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.017
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.017
|
Mouse |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.017
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.017
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.017
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.017
|
Mouse Worm |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.017
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.017
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.017
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.017
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.017
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.017
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.017
|
Fly |
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.017
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.017
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.017
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.017
|
Human |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.017
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.017
|
Mouse |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.017
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.017
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.016
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.016
|
Fly |
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.016
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.016
|
Human |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.016
|
Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.016
|
Human Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.016
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.016
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.016
|
Human |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.016
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.016
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.016
|
|
|
|
ectodermal placode morphogenesis
|
GO:0071697 |
1 |
0.016
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.016
|
Worm Fly |
|
|
taxis
|
GO:0042330 |
157 |
0.016
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.016
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.016
|
Fly |
|
|
autophagy
|
GO:0006914 |
88 |
0.016
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.016
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.015
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.015
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.015
|
Human |
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.015
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
Human |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.015
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.015
|
Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.015
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.015
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.015
|
Mouse |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.015
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.015
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.015
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.015
|
Fly |
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.015
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.015
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.015
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.015
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.015
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.015
|
Human |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.015
|
|
|
|
head development
|
GO:0060322 |
108 |
0.014
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.014
|
Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.014
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.014
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.014
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.014
|
Mouse Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.014
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.014
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.014
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.014
|
Human |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.014
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.014
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.014
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.014
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.014
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.014
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.014
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.014
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.014
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.014
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.014
|
Fly |
|
|
regulation of rna stability
|
GO:0043487 |
23 |
0.014
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.014
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.014
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.014
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.014
|
Human |
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.014
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.014
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.013
|
Human |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.013
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.013
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.013
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.013
|
Human |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.013
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.013
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.013
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.013
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.013
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.013
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.013
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.013
|
Mouse Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.013
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.013
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.013
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.013
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.013
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.013
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.013
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.013
|
Mouse |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.013
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.013
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.013
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.013
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.013
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.013
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.013
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.013
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.013
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.013
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.013
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.013
|
Fly |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.013
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.013
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.012
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.012
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.012
|
Mouse |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.012
|
Human |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.012
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.012
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
7 |
0.012
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.012
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.012
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.012
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.012
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.012
|
Fly |
|
|
regulation of rna splicing
|
GO:0043484 |
62 |
0.012
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.012
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.012
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.012
|
Human |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.012
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.012
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.012
|
Human Mouse |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.012
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.012
|
Human |
|
|
tachykinin receptor signaling pathway
|
GO:0007217 |
3 |
0.012
|
|
|
|
cellular response to parathyroid hormone stimulus
|
GO:0071374 |
2 |
0.012
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.012
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.012
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.012
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.012
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.012
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.012
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.012
|
Human Fly |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.012
|
Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.012
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.012
|
Mouse |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.011
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.011
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.011
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.011
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.011
|
|
|
|
secondary heart field specification
|
GO:0003139 |
2 |
0.011
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.011
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.011
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.011
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.011
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.011
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.011
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.011
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.011
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.011
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.011
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.011
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.011
|
|
|
|
mating
|
GO:0007618 |
1 |
0.011
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.011
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.011
|
Worm Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.011
|
Human |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.011
|
Mouse Fly |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.011
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.011
|
|
|
|
poly n acetyllactosamine metabolic process
|
GO:0030309 |
2 |
0.011
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.011
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.011
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.011
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.011
|
Human |
|
|
compound eye development
|
GO:0048749 |
1 |
0.011
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.011
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.011
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.011
|
Fly |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.011
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.011
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.011
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.011
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.011
|
|
|
|
growth
|
GO:0040007 |
202 |
0.011
|
Mouse Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.010
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.010
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.010
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.010
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.010
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.010
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.010
|
Fly |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.010
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.010
|
Fly |
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.010
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.010
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.010
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.010
|
Mouse Worm |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.010
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.010
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.010
|
Fly |
|
|
meiosis i
|
GO:0007127 |
4 |
0.010
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.010
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.010
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.010
|
Human Worm Fly |
