|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
1.000
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
1.000
|
Yeast |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
1.000
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
1.000
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
1.000
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
1.000
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
1.000
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
1.000
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
1.000
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
1.000
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
1.000
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
1.000
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
1.000
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
1.000
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
1.000
|
Worm |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
1.000
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
1.000
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
1.000
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
1.000
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
1.000
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
1.000
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
1.000
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
1.000
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
1.000
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
1.000
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.999
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.999
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.999
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.999
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.999
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.999
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.998
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.998
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.998
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.998
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.998
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.998
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.997
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.997
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.997
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.997
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.997
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.996
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.996
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.996
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.996
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.996
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.995
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.993
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.992
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.992
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.991
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.989
|
Worm Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.988
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.986
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.985
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.980
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.978
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.978
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.976
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.976
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.976
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.976
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.971
|
Worm |
|
|
innate immune response
|
GO:0045087 |
178 |
0.967
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.965
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.965
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.961
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.957
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.956
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.954
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.953
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.952
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.950
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.948
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.948
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.944
|
Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.940
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.940
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.937
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.935
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.935
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.927
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.917
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.912
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.903
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.900
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.899
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.898
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.895
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.894
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.890
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.880
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.871
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.867
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.853
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.852
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.850
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.847
|
|
|
|
growth
|
GO:0040007 |
202 |
0.847
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.847
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.843
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.842
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.837
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.833
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.833
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.830
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.815
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.813
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.811
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.806
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.805
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.803
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.797
|
Fly |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.787
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.776
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.774
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.766
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.756
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.745
|
Fly |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.742
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.741
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.740
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.739
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.722
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.709
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.705
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.702
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.701
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.700
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.692
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.690
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.679
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.679
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.658
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.642
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.638
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.636
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.629
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.617
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.602
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.602
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.598
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.589
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.585
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.578
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.562
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.549
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.537
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.533
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.522
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.516
|
Fly |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.516
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.504
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.502
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.499
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.468
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.465
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.454
|
Fly |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.451
|
Fly |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.445
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.444
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.442
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.432
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.427
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.424
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.414
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.413
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.410
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.408
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.400
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.382
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.375
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.372
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.370
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.364
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.360
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.349
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.325
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.323
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.322
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.320
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.318
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.313
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.313
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.312
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.302
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.296
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.295
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.286
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.275
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.274
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.272
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.267
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.257
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.256
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.256
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.255
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.252
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.252
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.238
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.237
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.233
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.233
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.228
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.226
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.224
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.221
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.211
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.203
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.203
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.201
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.192
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.190
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.182
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.176
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.169
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.168
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.166
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.165
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.165
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.159
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.157
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.155
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.153
|
Worm Fly |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.149
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.148
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.147
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.146
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.143
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.142
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.136
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.135
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.132
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.129
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.129
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.128
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.128
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.125
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.124
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.124
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.120
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.120
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.118
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.117
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.113
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.111
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.111
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.109
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.106
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.105
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.104
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.102
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.101
|
|
|
|
snrna modification
|
GO:0040031 |
1 |
0.100
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.096
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.096
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.092
|
|
|
|
aging
|
GO:0007568 |
66 |
0.091
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.089
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.088
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.086
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.085
|
Fly |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.085
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.084
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.082
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.080
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.080
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.079
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.077
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.077
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.077
|
|
|
|
positive regulation of mitotic cell cycle spindle assembly checkpoint
|
GO:0090267 |
6 |
0.076
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.075
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.075
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.073
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.072
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.072
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.071
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.066
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.065
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.065
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.064
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.064
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.063
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.063
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.063
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.061
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.059
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.058
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.056
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.055
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.055
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.053
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.053
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.052
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.051
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.051
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.051
|
|
|
|
ribosomal small subunit export from nucleus
|
GO:0000056 |
3 |
0.049
|
|
|
|
regulation of mitotic cell cycle spindle assembly checkpoint
|
GO:0090266 |
8 |
0.049
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.049
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.048
|
|
|
|
positive regulation of transcription of nuclear large rrna transcript from rna polymerase i promoter
|
GO:1901838 |
2 |
0.048
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.047
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.047
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.046
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.046
|
Mouse Fly |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.045
|
|
|
|
positive regulation of dna dependent dna replication
|
GO:2000105 |
7 |
0.045
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.044
|
|
|
|
polynucleotide dephosphorylation
|
GO:0098501 |
3 |
0.044
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.043
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.043
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.042
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.042
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.042
|
|
|
|
positive regulation of spindle checkpoint
|
GO:0090232 |
7 |
0.042
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.040
|
|
|
|
regulation of mitotic spindle checkpoint
|
GO:1903504 |
8 |
0.040
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.040
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.040
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.039
|
Worm |
|
|
response to hormone
|
GO:0009725 |
175 |
0.039
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.038
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.038
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.038
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.037
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.035
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.035
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.034
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.032
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.032
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.032
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.031
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.031
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.031
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.031
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.031
|
|
|
|
regulation of spindle checkpoint
|
GO:0090231 |
12 |
0.031
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.030
|
|
|
|
gene looping
|
GO:0090202 |
1 |
0.030
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.029
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.029
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.028
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.027
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.027
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.027
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.027
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.026
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.026
|
|
|
|
regulation of histone h4 k16 acetylation
|
GO:2000618 |
1 |
0.025
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.025
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.025
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.025
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.024
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.024
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.024
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.024
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.024
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.023
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.023
|
|
|
|
mature ribosome assembly
|
GO:0042256 |
5 |
0.023
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.023
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.023
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.023
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.023
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.022
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.022
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.022
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.022
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.022
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.022
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.022
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.022
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.022
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.022
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.021
|
Fly |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.021
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
positive regulation of peptidyl lysine acetylation
|
GO:2000758 |
12 |
0.020
|
|
|
|
positive regulation of single stranded viral rna replication via double stranded dna intermediate
|
GO:0045870 |
1 |
0.020
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.020
|
|
|
|
regulation of cellular respiration
|
GO:0043457 |
4 |
0.020
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.020
|
|
|
|
regulation of spindle assembly involved in mitosis
|
GO:1901673 |
1 |
0.020
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.020
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.020
|
Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.020
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.019
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.018
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.018
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.018
|
|
|
|
positive regulation of mitochondrial membrane potential
|
GO:0010918 |
1 |
0.018
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.018
|
|
|
|
transcriptional activation by promoter enhancer looping
|
GO:0071733 |
1 |
0.018
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.018
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.018
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.018
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.018
|
|
|
|
dsdna loop formation
|
GO:0090579 |
1 |
0.018
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.017
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.017
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.017
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.017
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.017
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.017
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.017
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.017
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.016
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.016
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.016
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.016
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.016
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.015
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.015
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.015
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.015
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.015
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.015
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.015
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.015
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.014
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
2 |
0.014
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.014
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.014
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.014
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.014
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.014
|
|
|
|
positive regulation of histone h4 k16 acetylation
|
GO:2000620 |
1 |
0.014
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.014
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.014
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.014
|
|
|
|
cenp a containing chromatin organization
|
GO:0061641 |
1 |
0.013
|
|
|
|
nuclear retention of pre mrna at the site of transcription
|
GO:0071033 |
1 |
0.013
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.013
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.013
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.013
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.013
|
|
|
|
ribosome assembly
|
GO:0042255 |
9 |
0.012
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.012
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.012
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.012
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.012
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.012
|
|
|
|
pyrimidine nucleoside monophosphate metabolic process
|
GO:0009129 |
1 |
0.012
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.012
|
|
|
|
protein deglycosylation
|
GO:0006517 |
2 |
0.012
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.012
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.012
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.011
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.011
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.011
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.011
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.011
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.011
|
|
|
|
regulation of mitotic recombination
|
GO:0000019 |
1 |
0.011
|
|
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.011
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.011
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.011
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.010
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.010
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.010
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.010
|
|
|
|
system process
|
GO:0003008 |
349 |
0.010
|
|
|
|
endomitotic cell cycle
|
GO:0007113 |
1 |
0.010
|
|