|
|
gtp metabolic process
|
GO:0046039 |
239 |
1.000
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.999
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.997
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.996
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.996
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.994
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.993
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.992
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.992
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.990
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.988
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.985
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.984
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.979
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.979
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.978
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.977
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.976
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.975
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.973
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.973
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.965
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.964
|
Human |
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.960
|
|
|
|
constitutive secretory pathway
|
GO:0045054 |
3 |
0.958
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.955
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.950
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.947
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.947
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.938
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.933
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.931
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.931
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.921
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.911
|
|
|
|
anterograde axon cargo transport
|
GO:0008089 |
1 |
0.904
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.897
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.887
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.827
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.821
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.821
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.817
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.808
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.802
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.799
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.775
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.754
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.754
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.744
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.743
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.741
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.741
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.737
|
|
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.737
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.736
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.733
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.731
|
|
|
|
phagosome acidification
|
GO:0090383 |
4 |
0.722
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.712
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.711
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.684
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.664
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.660
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.657
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.656
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.651
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.633
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.619
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.609
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.606
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.585
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.583
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.577
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.577
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.571
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.563
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.563
|
|
|
|
establishment of protein localization to endoplasmic reticulum membrane
|
GO:0097051 |
3 |
0.556
|
|
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.550
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.549
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.544
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.544
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.543
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.541
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.530
|
|
|
|
golgi vesicle fusion to target membrane
|
GO:0048210 |
2 |
0.528
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.510
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.497
|
Human Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.490
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.489
|
|
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.489
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.484
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.469
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.469
|
Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.441
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.428
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.421
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.420
|
|
|
|
endosomal vesicle fusion
|
GO:0034058 |
1 |
0.410
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.410
|
|
|
|
plasma membrane to endosome transport
|
GO:0048227 |
6 |
0.407
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.402
|
|
|
|
phagosome maturation
|
GO:0090382 |
9 |
0.394
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.393
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.391
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.390
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.380
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.377
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
10 |
0.368
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.366
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.363
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.344
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.338
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.337
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.335
|
|
|
|
regulation of atp metabolic process
|
GO:1903578 |
29 |
0.333
|
|
|
|
regulation of atp catabolic process
|
GO:1903289 |
25 |
0.327
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.325
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.302
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.300
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.295
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.286
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.285
|
|
|
|
positive regulation of glycoprotein metabolic process
|
GO:1903020 |
8 |
0.282
|
|
|
|
protein localization to peroxisome
|
GO:0072662 |
15 |
0.273
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.273
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.271
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.270
|
Human |
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.259
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.259
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.259
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.259
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.255
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.249
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.247
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.246
|
|
|
|
regulation of constitutive secretory pathway
|
GO:1903433 |
2 |
0.245
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.245
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.244
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.236
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.235
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.235
|
Human |
|
|
neurotransmitter transport
|
GO:0006836 |
10 |
0.232
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.228
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.225
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.219
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.217
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.217
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.217
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.212
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.209
|
|
|
|
multivesicular body organization
|
GO:0036257 |
2 |
0.208
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.205
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.203
|
|
|
|
peptidyl cysteine modification
|
GO:0018198 |
9 |
0.203
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.201
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.198
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.196
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.193
|
|
|
|
lytic vacuole organization
|
GO:0080171 |
24 |
0.191
|
|
|
|
endocytic recycling
|
GO:0032456 |
12 |
0.191
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.188
|
|
|
|
phagosome lysosome fusion
|
GO:0090385 |
4 |
0.187
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.181
|
|
|
|
regulation of intracellular ph
|
GO:0051453 |
16 |
0.176
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.175
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.175
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.167
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.165
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.165
|
Human |
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.162
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
19 |
0.158
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.156
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.155
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.147
|
Human Mouse Fly |
|
|
phagolysosome assembly
|
GO:0001845 |
5 |
0.147
|
|
|
|
embryonic axis specification
|
GO:0000578 |
5 |
0.146
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.146
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.144
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.144
|
|
|
|
peroxisomal transport
|
GO:0043574 |
15 |
0.142
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.142
|
Human |
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.140
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.138
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.136
|
|
|
|
cellular pigmentation
|
GO:0033059 |
17 |
0.133
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.132
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.129
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.127
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.126
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.126
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.125
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.124
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.124
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.124
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.123
|
Human |
|
|
protein targeting to peroxisome
|
GO:0006625 |
15 |
0.123
|
|
|
|
glucose transport
|
GO:0015758 |
30 |
0.121
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.121
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.120
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.119
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.119
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.119
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.118
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.117
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.113
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.112
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.110
|
Human |
|
|
growth hormone secretion
|
GO:0030252 |
4 |
0.108
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.107
|
Human |
|
|
autophagy
|
GO:0006914 |
88 |
0.107
|
|
|
|
multivesicular body assembly
|
GO:0036258 |
1 |
0.107
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.106
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.105
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.105
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.104
|
Human |
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.103
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.103
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.102
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.101
|
Human Mouse Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.100
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.099
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.097
|
|
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.096
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.093
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.092
|
|
|
|
receptor internalization involved in canonical wnt signaling pathway
|
GO:2000286 |
3 |
0.091
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.091
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.091
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.090
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.090
|
Human Fly |
|
|
cargo loading into vesicle
|
GO:0035459 |
5 |
0.089
|
|
|
|
protein localization to golgi apparatus
|
GO:0034067 |
13 |
0.089
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.089
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.088
|
|
|
|
protein targeting to golgi
|
GO:0000042 |
3 |
0.087
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.087
|
Human |
|
|
hormone transport
|
GO:0009914 |
68 |
0.087
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.087
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.085
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.084
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.082
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.081
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.081
|
|
|
|
melanosome localization
|
GO:0032400 |
7 |
0.081
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.081
|
Fly |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.078
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.077
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.076
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.075
|
|
|
|
establishment of pigment granule localization
|
GO:0051905 |
5 |
0.075
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
15 |
0.074
|
|
|
|
regulation of glycoprotein metabolic process
|
GO:1903018 |
19 |
0.072
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.072
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.072
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.071
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.070
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.069
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.069
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.069
|
|
|
|
establishment of protein localization to peroxisome
|
GO:0072663 |
15 |
0.068
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.066
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
5 |
0.066
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.064
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.064
|
|
|
|
fertilization
|
GO:0009566 |
12 |
0.062
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.062
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.061
|
Human Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.061
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.061
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.061
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.060
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.060
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.059
|
Human Fly |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.059
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.058
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.058
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.058
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.056
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.056
|
|
|
|
vesicle docking involved in exocytosis
|
GO:0006904 |
3 |
0.055
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.055
|
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.055
|
Human |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.055
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.055
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.054
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.054
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.054
|
|
|
|
establishment of protein localization to golgi
|
GO:0072600 |
4 |
0.054
|
|
|
|
pigment granule localization
|
GO:0051875 |
7 |
0.054
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.054
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.053
|
Human |
|
|
golgi to endosome transport
|
GO:0006895 |
7 |
0.053
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.051
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.051
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
7 |
0.051
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.050
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.050
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.050
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.049
|
|
|
|
intracellular protein transmembrane import
|
GO:0044743 |
23 |
0.049
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.049
|
Human |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.049
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.049
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.049
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.049
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.048
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.048
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.047
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.047
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.047
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.047
|
|
|
|
secretory granule organization
|
GO:0033363 |
2 |
0.046
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.046
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.046
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.046
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.045
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.045
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.045
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.045
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.045
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.045
|
Human |
|
|
axis specification
|
GO:0009798 |
12 |
0.044
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.044
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.044
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.044
|
|
|
|
aging
|
GO:0007568 |
66 |
0.043
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.043
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.042
|
|
|
|
cellular monovalent inorganic cation homeostasis
|
GO:0030004 |
26 |
0.042
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.042
|
Mouse |
|
|
golgi to plasma membrane transport
|
GO:0006893 |
21 |
0.041
|
|
|
|
lysosome organization
|
GO:0007040 |
24 |
0.041
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.041
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.040
|
|
|
|
virion assembly
|
GO:0019068 |
14 |
0.040
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.039
|
Human |
|
|
response to hormone
|
GO:0009725 |
175 |
0.039
|
Human |
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
15 |
0.038
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.038
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.037
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.037
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.037
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.037
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.037
|
|
|
|
regulation of ph
|
GO:0006885 |
20 |
0.037
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.037
|
Human |
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
10 |
0.037
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.037
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.036
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.036
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.036
|
Human |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.036
|
|
|
|
negative regulation of constitutive secretory pathway
|
GO:1903434 |
1 |
0.036
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.036
|
|
|
|
vesicle transport along microtubule
|
GO:0047496 |
4 |
0.036
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.036
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.036
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.036
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.036
|
|
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.035
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.035
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.035
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.035
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.035
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.035
|
Human |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.035
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.035
|
Human |
|
|
hexose transport
|
GO:0008645 |
30 |
0.035
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.035
|
|
|
|
natural killer cell activation involved in immune response
|
GO:0002323 |
2 |
0.034
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.034
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.034
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.034
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.034
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.034
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.034
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.034
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
6 |
0.033
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.033
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.033
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.033
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.033
|
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.033
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.033
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.032
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.032
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.032
|
Human |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.032
|
|
|
|
peptidyl cysteine methylation
|
GO:0018125 |
1 |
0.032
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.031
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.031
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.031
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.031
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.030
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.030
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.030
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.030
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.030
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.030
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.030
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.030
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.030
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.029
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.029
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.029
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.029
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.029
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.029
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.029
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.029
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.029
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
39 |
0.029
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.029
|
|
|
|
pigmentation
|
GO:0043473 |
22 |
0.029
|
|
|
|
positive regulation of atp catabolic process
|
GO:1903291 |
19 |
0.028
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.028
|
Human |
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
3 |
0.028
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.028
|
Human Fly |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.028
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.027
|
Human |
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.027
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.027
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.027
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.027
|
Human |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.026
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.026
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.026
|
Human |
|
|
reproductive process
|
GO:0022414 |
106 |
0.026
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.026
|
Human |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.026
|
Human |
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.026
|
|
|
|
endoplasmic reticulum tubular network organization
|
GO:0071786 |
8 |
0.025
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.025
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.025
|
|
|
|
golgi inheritance
|
GO:0048313 |
2 |
0.025
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.025
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.025
|
|
|
|
regulation of cellular ph
|
GO:0030641 |
17 |
0.025
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.025
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.025
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.024
|
Human |
|
|
negative regulation of carbohydrate metabolic process
|
GO:0045912 |
20 |
0.024
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.024
|
Human Fly |
|
|
autophagic vacuole assembly
|
GO:0000045 |
19 |
0.024
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.024
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.024
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.024
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.024
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.023
|
Human |
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.023
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.023
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.023
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.023
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.023
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.023
|
|
|
|
negative regulation of hyaluronan biosynthetic process
|
GO:1900126 |
3 |
0.023
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.023
|
|
|
|
negative regulation of posttranscriptional gene silencing
|
GO:0060149 |
3 |
0.023
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.023
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.023
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.023
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.022
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.022
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.022
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.022
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.022
|
Human |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.022
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.022
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.022
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.022
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.022
|
|
|
|
intra golgi vesicle mediated transport
|
GO:0006891 |
8 |
0.022
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.022
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.022
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.022
|
Fly |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.022
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.021
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.021
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.021
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.021
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.021
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
35 |
0.021
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.021
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.021
|
|
