Homo sapiens

0 known processes

HECW1

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

(Aliases: KIAA0322,NEDL1)

HECW1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gamma aminobutyric acid signaling pathway GO:0007214 3 0.558
ion transmembrane transport GO:0034220 338 0.325
locomotory behavior GO:0007626 1 0.164
inorganic ion transmembrane transport GO:0098660 231 0.159
transmembrane transport GO:0055085 399 0.149
metal ion transport GO:0030001 272 0.106
cation transport GO:0006812 331 0.100
inorganic cation transmembrane transport GO:0098662 194 0.098
regulation of ion transport GO:0043269 189 0.089
regulation of transmembrane transport GO:0034762 139 0.080
regulation of ion transmembrane transport GO:0034765 132 0.077
lipid metabolic process GO:0006629 381 0.074
system process GO:0003008 349 0.073
cation transmembrane transport GO:0098655 238 0.072
chemical homeostasis GO:0048878 306 0.072
mating GO:0007618 1 0.072
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.067
g protein coupled receptor signaling pathway GO:0007186 207 0.065
positive regulation of developmental process GO:0051094 314 0.065
protein catabolic process GO:0030163 325 0.064
cation homeostasis GO:0055080 189 0.063
metal ion homeostasis GO:0055065 169 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.062
organophosphate catabolic process GO:0046434 430 0.060
sensory perception of pain GO:0019233 4 0.060
modification dependent protein catabolic process GO:0019941 209 0.060
regulation of neurotransmitter secretion GO:0046928 3 0.060
regulation of cell differentiation GO:0045595 393 0.059
regulation of nucleotide metabolic process GO:0006140 269 0.058
ion homeostasis GO:0050801 230 0.058
metencephalon development GO:0022037 2 0.057
glycosyl compound catabolic process GO:1901658 413 0.053
cellular calcium ion homeostasis GO:0006874 117 0.051
multicellular organismal response to stress GO:0033555 1 0.051
cellular chemical homeostasis GO:0055082 180 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.050
ventral spinal cord development GO:0021517 1 0.050
regulation of metal ion transport GO:0010959 120 0.049
post embryonic development GO:0009791 2 0.049
neurological system process GO:0050877 163 0.049
response to abiotic stimulus GO:0009628 336 0.047
single organism membrane organization GO:0044802 268 0.047
organic hydroxy compound metabolic process GO:1901615 147 0.047
cellular ion homeostasis GO:0006873 168 0.047
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.046
purine nucleoside catabolic process GO:0006152 398 0.046
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.046
positive regulation of transport GO:0051050 336 0.045
ribonucleotide catabolic process GO:0009261 405 0.045
ribonucleoside catabolic process GO:0042454 406 0.045
positive regulation of cellular component organization GO:0051130 376 0.045
membrane organization GO:0061024 292 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.043
muscle contraction GO:0006936 73 0.043
cerebellum development GO:0021549 2 0.043
lipid biosynthetic process GO:0008610 177 0.043
cellular protein catabolic process GO:0044257 261 0.043
carbohydrate metabolic process GO:0005975 207 0.041
cellular homeostasis GO:0019725 196 0.041
cellular cation homeostasis GO:0030003 163 0.041
positive regulation of nucleotide metabolic process GO:0045981 230 0.041
positive regulation of cell proliferation GO:0008284 301 0.039
sa node cell action potential GO:0086015 1 0.039
hindbrain development GO:0030902 3 0.038
nucleotide catabolic process GO:0009166 408 0.038
sensory perception GO:0007600 103 0.038
cell projection organization GO:0030030 252 0.037
regulation of membrane potential GO:0042391 95 0.037
modification dependent macromolecule catabolic process GO:0043632 212 0.037
regulation of proteolysis GO:0030162 293 0.037
cellular macromolecule catabolic process GO:0044265 380 0.037
spinal cord development GO:0021510 4 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.035
amino acid transport GO:0006865 28 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
neuromuscular junction development GO:0007528 3 0.035
cell development GO:0048468 328 0.034
ribonucleotide biosynthetic process GO:0009260 81 0.034
divalent inorganic cation homeostasis GO:0072507 136 0.034
cellular metal ion homeostasis GO:0006875 146 0.034
methylation GO:0032259 106 0.033
single organism cellular localization GO:1902580 332 0.033
organophosphate biosynthetic process GO:0090407 163 0.033
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.033
positive regulation of phosphorylation GO:0042327 394 0.033
female gamete generation GO:0007292 2 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.032
protein modification by small protein conjugation GO:0032446 342 0.032
purine containing compound biosynthetic process GO:0072522 88 0.032
secretion by cell GO:0032940 226 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.031
chromatin organization GO:0006325 351 0.031
positive regulation of immune system process GO:0002684 283 0.031
purine containing compound catabolic process GO:0072523 411 0.031
nervous system development GO:0007399 293 0.031
cyclic nucleotide biosynthetic process GO:0009190 61 0.030
covalent chromatin modification GO:0016569 254 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
protein localization to membrane GO:0072657 160 0.030
ras protein signal transduction GO:0007265 73 0.030
mitotic cell cycle GO:0000278 326 0.030
positive regulation of cellular component biogenesis GO:0044089 158 0.030
nucleoside phosphate biosynthetic process GO:1901293 109 0.029
cellular lipid metabolic process GO:0044255 303 0.029
positive regulation of organelle organization GO:0010638 195 0.029
cellular divalent inorganic cation homeostasis GO:0072503 128 0.029
purine ribonucleotide catabolic process GO:0009154 404 0.029
regulation of hormone levels GO:0010817 125 0.029
regulation of cellular component movement GO:0051270 334 0.029
detection of stimulus GO:0051606 85 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
anion transport GO:0006820 161 0.028
cytokine production GO:0001816 247 0.028
protein ubiquitination GO:0016567 314 0.028
cell differentiation in spinal cord GO:0021515 1 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
divalent inorganic cation transport GO:0072511 158 0.027
macromolecule methylation GO:0043414 97 0.027
regulation of transferase activity GO:0051338 355 0.027
monovalent inorganic cation transport GO:0015672 128 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.027
cell cell signaling GO:0007267 155 0.027
divalent metal ion transport GO:0070838 152 0.027
vesicle mediated transport GO:0016192 371 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
ribose phosphate biosynthetic process GO:0046390 82 0.027
multicellular organismal aging GO:0010259 3 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
ubiquitin dependent protein catabolic process GO:0006511 206 0.027
cellular amino acid metabolic process GO:0006520 116 0.027
membrane repolarization during sa node cell action potential GO:0086052 1 0.026
calcium ion transport GO:0006816 147 0.026
nitrogen compound transport GO:0071705 191 0.026
circulatory system process GO:0003013 113 0.026
actin filament based process GO:0030029 224 0.026
purine nucleotide biosynthetic process GO:0006164 84 0.026
detection of stimulus involved in sensory perception GO:0050906 43 0.025
generation of neurons GO:0048699 152 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
regulation of protein catabolic process GO:0042176 155 0.025
cellular response to oxygen containing compound GO:1901701 276 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
sensory perception of light stimulus GO:0050953 35 0.025
protein maturation GO:0051604 233 0.024
cytoplasmic transport GO:0016482 379 0.024
negative regulation of developmental process GO:0051093 247 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
determination of adult lifespan GO:0008340 2 0.024
oogenesis GO:0048477 2 0.024
regulation of kinase activity GO:0043549 314 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
organic anion transport GO:0015711 103 0.023
regulation of secretion GO:0051046 194 0.023
regulation of secretion by cell GO:1903530 177 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.022
gtp metabolic process GO:0046039 239 0.022
cytosolic calcium ion homeostasis GO:0051480 89 0.022
memory GO:0007613 3 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
calcium ion homeostasis GO:0055074 122 0.022
histone modification GO:0016570 251 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
nerve development GO:0021675 4 0.022
response to oxygen containing compound GO:1901700 369 0.022
nucleoside catabolic process GO:0009164 408 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.022
negative regulation of cell differentiation GO:0045596 171 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.021
immune system development GO:0002520 195 0.021
negative regulation of cell death GO:0060548 345 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
regulation of system process GO:0044057 101 0.021
steroid metabolic process GO:0008202 94 0.021
atp catabolic process GO:0006200 157 0.021
cell morphogenesis GO:0000902 296 0.021
immune response GO:0006955 307 0.021
regulation of calcium ion transport GO:0051924 79 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
regulation of homeostatic process GO:0032844 121 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
regulation of cell development GO:0060284 161 0.020
positive regulation of cell differentiation GO:0045597 211 0.020
positive regulation of transferase activity GO:0051347 227 0.020
muscle system process GO:0003012 81 0.020
positive regulation of nucleotide catabolic process GO:0030813 185 0.020
sensory perception of mechanical stimulus GO:0050954 37 0.020
sulfur compound metabolic process GO:0006790 101 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
actin filament based movement GO:0030048 17 0.020
limbic system development GO:0021761 3 0.020
regulation of cellular response to stress GO:0080135 244 0.020
multicellular organismal signaling GO:0035637 34 0.020
negative regulation of protein maturation GO:1903318 142 0.020
regulation of cell cycle GO:0051726 393 0.020
regulation of transmembrane transporter activity GO:0022898 74 0.020
ribonucleoside monophosphate catabolic process GO:0009158 158 0.020
secretion GO:0046903 254 0.020
purine ribonucleotide biosynthetic process GO:0009152 79 0.020
sodium ion transport GO:0006814 61 0.019
regulation of protein localization GO:0032880 296 0.019
cellular ketone metabolic process GO:0042180 80 0.019
cellular component morphogenesis GO:0032989 314 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
protein localization to organelle GO:0033365 280 0.019
cyclic nucleotide metabolic process GO:0009187 82 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
regulation of synaptic plasticity GO:0048167 3 0.019
maintenance of location GO:0051235 112 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
protein oligomerization GO:0051259 173 0.019
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.019
gtp catabolic process GO:0006184 237 0.019
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.019
nucleotide biosynthetic process GO:0009165 109 0.019
action potential GO:0001508 34 0.019
positive regulation of ion transport GO:0043270 87 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
defense response GO:0006952 315 0.018
startle response GO:0001964 3 0.018
mapk cascade GO:0000165 288 0.018
response to axon injury GO:0048678 1 0.018
associative learning GO:0008306 1 0.018
regulation of cytokine production GO:0001817 232 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
negative regulation of synaptic transmission GO:0050805 2 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
oocyte differentiation GO:0009994 2 0.018
regulation of mapk cascade GO:0043408 262 0.018
regulation of protein kinase activity GO:0045859 289 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
negative regulation of organelle organization GO:0010639 126 0.018
behavior GO:0007610 112 0.018
blastocyst development GO:0001824 3 0.018
positive regulation of synaptic transmission GO:0050806 4 0.018
cellular macromolecular complex assembly GO:0034622 324 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
cell growth GO:0016049 160 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
organic acid transport GO:0015849 65 0.017
calcium ion transmembrane transport GO:0070588 76 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
regeneration GO:0031099 4 0.017
sulfur amino acid metabolic process GO:0000096 14 0.017
sodium ion transmembrane transport GO:0035725 59 0.017
neurogenesis GO:0022008 169 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
synaptic transmission GO:0007268 61 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
anterior posterior axis specification GO:0009948 2 0.017
mitotic cell cycle process GO:1903047 286 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
regulation of chromosome organization GO:0033044 103 0.017
protein processing GO:0016485 226 0.017
negative regulation of protein modification process GO:0031400 200 0.017
dephosphorylation GO:0016311 209 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
t cell differentiation in thymus GO:0033077 4 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
epithelial fluid transport GO:0042045 1 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
neuron development GO:0048666 113 0.016
response to lipid GO:0033993 206 0.016
synaptic transmission involved in micturition GO:0060084 2 0.016
cell type specific apoptotic process GO:0097285 125 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
regulation of cyclase activity GO:0031279 19 0.016
monosaccharide metabolic process GO:0005996 74 0.016
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.016
segmentation GO:0035282 4 0.016
alcohol metabolic process GO:0006066 114 0.016
neurotransmitter secretion GO:0007269 4 0.016
cellular response to lipid GO:0071396 127 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
nucleoside monophosphate metabolic process GO:0009123 191 0.016
neuron differentiation GO:0030182 138 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
endomembrane system organization GO:0010256 196 0.016
exocytosis GO:0006887 71 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
cellular amine metabolic process GO:0044106 41 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
chromatin modification GO:0016568 298 0.015
atp metabolic process GO:0046034 176 0.015
negative regulation of chromosome organization GO:2001251 48 0.015
positive regulation of axon extension GO:0045773 4 0.015
amine metabolic process GO:0009308 44 0.015
skeletal system development GO:0001501 79 0.015
regulation of exocytosis GO:0017157 46 0.015
response to external biotic stimulus GO:0043207 261 0.015
carboxylic acid transport GO:0046942 63 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
leukocyte differentiation GO:0002521 98 0.015
oocyte development GO:0048599 1 0.015
rhythmic behavior GO:0007622 2 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
regulation of locomotion GO:0040012 329 0.015
cell division GO:0051301 168 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
positive regulation of map kinase activity GO:0043406 80 0.015
positive regulation of catabolic process GO:0009896 310 0.015
purine nucleotide catabolic process GO:0006195 405 0.014
regulation of feeding behavior GO:0060259 3 0.014
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.014
endocytosis GO:0006897 159 0.014
regulation of heart contraction GO:0008016 50 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
regulation of cell motility GO:2000145 299 0.014
regulation of protein complex assembly GO:0043254 147 0.014
regulation of protein binding GO:0043393 66 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
membrane repolarization GO:0086009 23 0.014
small molecule biosynthetic process GO:0044283 157 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
negative regulation of transport GO:0051051 176 0.014
positive regulation of protein complex assembly GO:0031334 86 0.014
sequestering of metal ion GO:0051238 24 0.014
positive regulation of cell motility GO:2000147 177 0.014
vasculature development GO:0001944 181 0.014
regulation of cell cycle process GO:0010564 266 0.014
adult locomotory behavior GO:0008344 1 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
visual behavior GO:0007632 2 0.014
organelle fission GO:0048285 149 0.013
camp metabolic process GO:0046058 61 0.013
intracellular protein transport GO:0006886 270 0.013
negative regulation of catabolic process GO:0009895 104 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
response to radiation GO:0009314 151 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
sensory perception of taste GO:0050909 36 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
hair cell differentiation GO:0035315 2 0.013
trophectodermal cell differentiation GO:0001829 3 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
dna repair GO:0006281 198 0.013
blastoderm segmentation GO:0007350 2 0.013
cellular protein complex assembly GO:0043623 188 0.013
microtubule based process GO:0007017 210 0.013
regulation of chromatin modification GO:1903308 51 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
protein methylation GO:0006479 74 0.013
innate immune response GO:0045087 178 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 4 0.013
hemopoiesis GO:0030097 180 0.013
cytokinesis GO:0000910 96 0.013
regulation of response to external stimulus GO:0032101 222 0.013
positive regulation of kinase activity GO:0033674 204 0.013
spermatid differentiation GO:0048515 4 0.013
rho protein signal transduction GO:0007266 26 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
histone methylation GO:0016571 60 0.013
regulation of intracellular transport GO:0032386 195 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.013
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.013
camp biosynthetic process GO:0006171 47 0.013
reproductive process GO:0022414 106 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
response to hypoxia GO:0001666 96 0.012
regulation of blood circulation GO:1903522 59 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
striated muscle contraction GO:0006941 52 0.012
growth GO:0040007 202 0.012
positive regulation of cytokine production GO:0001819 167 0.012
regulation of dna metabolic process GO:0051052 153 0.012
regulation of binding GO:0051098 111 0.012
regulation of camp biosynthetic process GO:0030817 45 0.012
regulation of protein transport GO:0051223 213 0.012
plasma membrane organization GO:0007009 115 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
stem cell division GO:0017145 2 0.012
response to oxygen levels GO:0070482 100 0.012
taxis GO:0042330 157 0.012
thyroid hormone metabolic process GO:0042403 4 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
steroid biosynthetic process GO:0006694 46 0.012
epithelial cell proliferation GO:0050673 128 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
regulation of neuron differentiation GO:0045664 70 0.012
nuclear division GO:0000280 128 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
response to inorganic substance GO:0010035 127 0.012
brain development GO:0007420 97 0.012
central nervous system development GO:0007417 123 0.012
male genitalia development GO:0030539 1 0.012
developmental programmed cell death GO:0010623 3 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
activation of immune response GO:0002253 114 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
multi organism cellular process GO:0044764 156 0.012
response to organic cyclic compound GO:0014070 204 0.012
positive regulation of cell death GO:0010942 263 0.012
actin filament organization GO:0007015 128 0.012
negative regulation of calcidiol 1 monooxygenase activity GO:0010956 3 0.012
circulatory system development GO:0072359 262 0.012
myeloid cell differentiation GO:0030099 117 0.012
tripartite regional subdivision GO:0007351 2 0.011
circadian behavior GO:0048512 2 0.011
regulation of cell projection organization GO:0031344 107 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
transmission of nerve impulse GO:0019226 11 0.011
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.011
tachykinin receptor signaling pathway GO:0007217 3 0.011
neuron projection development GO:0031175 106 0.011
oxidation reduction process GO:0055114 396 0.011
regulation of protein maturation GO:1903317 150 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
cellular modified amino acid metabolic process GO:0006575 64 0.011
calcium ion import GO:0070509 23 0.011
immune response regulating signaling pathway GO:0002764 97 0.011
rna processing GO:0006396 255 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
regulation of heart rate GO:0002027 38 0.011
cerebellar cortex development GO:0021695 1 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
spermatid development GO:0007286 4 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of cell division GO:0051302 116 0.011
cardiac muscle cell action potential GO:0086001 23 0.011
detection of mechanical stimulus GO:0050982 4 0.011
potassium ion transport GO:0006813 62 0.011
drinking behavior GO:0042756 1 0.011
autophagy GO:0006914 88 0.011
neuron projection regeneration GO:0031102 1 0.011
regulation of meiosis GO:0040020 3 0.011
blood circulation GO:0008015 113 0.011
protein secretion GO:0009306 98 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
actin cytoskeleton organization GO:0030036 207 0.011
myeloid leukocyte differentiation GO:0002573 60 0.011
musculoskeletal movement GO:0050881 17 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of immune response GO:0050776 201 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
negative regulation of chromatin modification GO:1903309 21 0.011
regulation of growth GO:0040008 165 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
protein targeting GO:0006605 187 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
positive regulation of immune response GO:0050778 159 0.010
glycerolipid metabolic process GO:0046486 107 0.010
negative regulation of cell cycle GO:0045786 193 0.010
regulation of neurogenesis GO:0050767 82 0.010
positive regulation of acrosome reaction GO:2000344 4 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
regulation of myeloid cell differentiation GO:0045637 81 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
regulation of steroid biosynthetic process GO:0050810 23 0.010
positive regulation of calcium ion transport GO:0051928 51 0.010
regulation of gtpase activity GO:0043087 180 0.010
regulation of neuron projection development GO:0010975 57 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
sensory perception of chemical stimulus GO:0007606 38 0.010
stress activated mapk cascade GO:0051403 93 0.010

HECW1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.044
nervous system disease DOID:863 431 0.044
sensory system disease DOID:0050155 203 0.036
neurodegenerative disease DOID:1289 102 0.030
retinal disease DOID:5679 118 0.024
eye and adnexa disease DOID:1492 150 0.024
eye disease DOID:5614 149 0.024
disease of metabolism DOID:0014667 295 0.021
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.020
brain disease DOID:936 73 0.016
neuropathy DOID:870 52 0.012
neuromuscular disease DOID:440 38 0.012
auditory system disease DOID:2742 53 0.011
renal tubular transport disease DOID:447 11 0.011
kidney disease DOID:557 36 0.011
urinary system disease DOID:18 40 0.011
retinal degeneration DOID:8466 89 0.010