Homo sapiens

68 known processes

RFWD3

ring finger and WD repeat domain 3

(Aliases: FLJ10520,RNF201)

RFWD3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.374
protein ubiquitination GO:0016567 314 0.364
mitotic cell cycle GO:0000278 326 0.337
cellular response to dna damage stimulus GO:0006974 379 0.170
protein polyubiquitination GO:0000209 110 0.160
modification dependent protein catabolic process GO:0019941 209 0.145
modification dependent macromolecule catabolic process GO:0043632 212 0.115
mitotic cell cycle process GO:1903047 286 0.115
protein catabolic process GO:0030163 325 0.114
cellular component morphogenesis GO:0032989 314 0.112
multicellular organismal aging GO:0010259 3 0.109
vesicle mediated transport GO:0016192 371 0.097
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.087
cellular macromolecular complex assembly GO:0034622 324 0.083
cellular protein catabolic process GO:0044257 261 0.073
chromatin modification GO:0016568 298 0.071
regulation of mitotic cell cycle GO:0007346 189 0.069
cellular protein complex assembly GO:0043623 188 0.065
dna repair GO:0006281 198 0.063
dna packaging GO:0006323 77 0.062
covalent chromatin modification GO:0016569 254 0.061
ras protein signal transduction GO:0007265 73 0.060
chromatin organization GO:0006325 351 0.060
regulation of cell cycle GO:0051726 393 0.059
ubiquitin dependent protein catabolic process GO:0006511 206 0.059
negative regulation of cell cycle process GO:0010948 121 0.058
determination of adult lifespan GO:0008340 2 0.058
microtubule cytoskeleton organization GO:0000226 176 0.057
double strand break repair GO:0006302 101 0.056
actin filament based process GO:0030029 224 0.054
membrane organization GO:0061024 292 0.052
nervous system development GO:0007399 293 0.051
recombinational repair GO:0000725 50 0.049
protein localization to organelle GO:0033365 280 0.048
locomotory behavior GO:0007626 1 0.047
nuclear division GO:0000280 128 0.044
neurogenesis GO:0022008 169 0.042
embryo development GO:0009790 123 0.041
dna recombination GO:0006310 77 0.041
cell morphogenesis GO:0000902 296 0.041
cell projection morphogenesis GO:0048858 129 0.039
single organism cellular localization GO:1902580 332 0.039
adult locomotory behavior GO:0008344 1 0.037
organelle assembly GO:0070925 176 0.037
microtubule based process GO:0007017 210 0.036
cell development GO:0048468 328 0.035
organelle fission GO:0048285 149 0.033
cellular amino acid metabolic process GO:0006520 116 0.032
dna replication GO:0006260 116 0.032
cellular macromolecule catabolic process GO:0044265 380 0.031
immune system development GO:0002520 195 0.031
double strand break repair via homologous recombination GO:0000724 50 0.030
meiotic chromosome segregation GO:0045132 4 0.030
mitotic nuclear division GO:0007067 119 0.030
regulation of cell cycle phase transition GO:1901987 126 0.029
positive regulation of immune system process GO:0002684 283 0.029
regulation of dna repair GO:0006282 47 0.029
negative regulation of cell cycle phase transition GO:1901988 89 0.029
small gtpase mediated signal transduction GO:0007264 78 0.028
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
regulation of cell cycle process GO:0010564 266 0.028
negative regulation of cell death GO:0060548 345 0.028
generation of neurons GO:0048699 152 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
female gamete generation GO:0007292 2 0.027
negative regulation of apoptotic process GO:0043066 316 0.026
endocytosis GO:0006897 159 0.026
cellular ketone metabolic process GO:0042180 80 0.026
blastocyst development GO:0001824 3 0.026
response to abiotic stimulus GO:0009628 336 0.026
growth GO:0040007 202 0.025
reproductive process GO:0022414 106 0.025
apoptotic signaling pathway GO:0097190 268 0.025
post embryonic development GO:0009791 2 0.025
nucleus organization GO:0006997 28 0.024
cell part morphogenesis GO:0032990 137 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
dna conformation change GO:0071103 113 0.024
dna dependent dna replication GO:0006261 44 0.024
purine containing compound catabolic process GO:0072523 411 0.024
amine metabolic process GO:0009308 44 0.023
cellular amine metabolic process GO:0044106 41 0.023
sister chromatid segregation GO:0000819 54 0.023
proteasomal protein catabolic process GO:0010498 176 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
nucleotide catabolic process GO:0009166 408 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
intracellular protein transport GO:0006886 270 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
chromosome segregation GO:0007059 114 0.022
cell projection organization GO:0030030 252 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
hemopoiesis GO:0030097 180 0.021
ribonucleoside monophosphate catabolic process GO:0009158 158 0.020
behavior GO:0007610 112 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.020
histone modification GO:0016570 251 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
mrna metabolic process GO:0016071 175 0.020
dna damage checkpoint GO:0000077 68 0.020
g1 s transition of mitotic cell cycle GO:0000082 78 0.020
positive regulation of organelle organization GO:0010638 195 0.020
regulation of locomotion GO:0040012 329 0.020
positive regulation of developmental process GO:0051094 314 0.020
regulation of cellular response to stress GO:0080135 244 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
positive regulation of transferase activity GO:0051347 227 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
base excision repair GO:0006284 21 0.019
segmentation GO:0035282 4 0.019
oogenesis GO:0048477 2 0.019
maintenance of location GO:0051235 112 0.019
regulation of cellular component movement GO:0051270 334 0.019
response to radiation GO:0009314 151 0.018
regulation of cell division GO:0051302 116 0.018
regulation of chromosome organization GO:0033044 103 0.018
protein localization to nucleus GO:0034504 136 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
dna integrity checkpoint GO:0031570 71 0.018
positive regulation of dna metabolic process GO:0051054 73 0.017
nucleoside catabolic process GO:0009164 408 0.017
wnt signaling pathway GO:0016055 156 0.017
single organism membrane organization GO:0044802 268 0.017
actin cytoskeleton organization GO:0030036 207 0.017
mitotic sister chromatid segregation GO:0000070 53 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
nuclear transport GO:0051169 179 0.017
regulation of transferase activity GO:0051338 355 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
regulation of meiosis GO:0040020 3 0.017
neuron projection development GO:0031175 106 0.017
response to ionizing radiation GO:0010212 65 0.017
defense response GO:0006952 315 0.016
positive regulation of cell death GO:0010942 263 0.016
nuclear migration GO:0007097 1 0.016
cytoplasmic transport GO:0016482 379 0.016
response to fungus GO:0009620 4 0.016
protein targeting GO:0006605 187 0.016
cell division GO:0051301 168 0.016
negative regulation of cell cycle GO:0045786 193 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
negative regulation of meiotic cell cycle GO:0051447 2 0.016
epithelium development GO:0060429 227 0.016
neuromuscular junction development GO:0007528 3 0.015
regulation of protein localization GO:0032880 296 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
regulation of dna metabolic process GO:0051052 153 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
regulation of growth GO:0040008 165 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
regulation of proteasomal protein catabolic process GO:0061136 87 0.015
cell cycle phase transition GO:0044770 173 0.015
striated muscle myosin thick filament assembly GO:0071688 2 0.015
regulation of protein maturation GO:1903317 150 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
embryonic epithelial tube formation GO:0001838 4 0.014
regulation of protein processing GO:0070613 150 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
positive regulation of immune response GO:0050778 159 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
rna processing GO:0006396 255 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
neuron differentiation GO:0030182 138 0.014
negative regulation of mitotic cell cycle GO:0045930 102 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
reproduction GO:0000003 63 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
receptor mediated endocytosis GO:0006898 84 0.013
regulation of cell differentiation GO:0045595 393 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
neuroblast proliferation GO:0007405 4 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
neuron development GO:0048666 113 0.013
establishment of nucleus localization GO:0040023 1 0.013
response to cytokine GO:0034097 232 0.013
regulation of protein ubiquitination GO:0031396 95 0.013
positive regulation of transport GO:0051050 336 0.013
regulation of protein catabolic process GO:0042176 155 0.013
lymphocyte activation GO:0046649 133 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
cell activation GO:0001775 213 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
cell cycle checkpoint GO:0000075 117 0.012
maintenance of location in cell GO:0051651 62 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
myosin filament organization GO:0031033 2 0.012
oocyte development GO:0048599 1 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
negative regulation of catabolic process GO:0009895 104 0.012
oocyte differentiation GO:0009994 2 0.012
central nervous system development GO:0007417 123 0.012
leukocyte activation GO:0045321 164 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
single organism reproductive process GO:0044702 98 0.012
positive regulation of catabolic process GO:0009896 310 0.012
regulation of proteolysis GO:0030162 293 0.012
macromolecule methylation GO:0043414 97 0.012
negative regulation of protein metabolic process GO:0051248 391 0.012
system process GO:0003008 349 0.012
protein processing GO:0016485 226 0.012
cell fate determination GO:0001709 3 0.012
myosin filament assembly GO:0031034 2 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
single organism nuclear import GO:1902593 104 0.012
organ morphogenesis GO:0009887 147 0.011
regulation of microtubule based process GO:0032886 74 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.011
regulation of multi organism process GO:0043900 157 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
chromatin remodeling at centromere GO:0031055 2 0.011
neural tube formation GO:0001841 3 0.011
protein import into nucleus GO:0006606 104 0.011
regulation of microtubule cytoskeleton organization GO:0070507 61 0.011
regulation of cell motility GO:2000145 299 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
centrosome organization GO:0051297 58 0.011
chromatin assembly or disassembly GO:0006333 78 0.011
interspecies interaction between organisms GO:0044419 156 0.011
reproductive structure development GO:0048608 55 0.011
mitotic nuclear envelope reassembly GO:0007084 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
chordate embryonic development GO:0043009 34 0.011
purine nucleoside catabolic process GO:0006152 398 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
negative regulation of protein catabolic process GO:0042177 59 0.010
internal peptidyl lysine acetylation GO:0018393 97 0.010
protein import GO:0017038 130 0.010
negative regulation of proteolysis GO:0045861 132 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
oxidation reduction process GO:0055114 396 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010
spermatid differentiation GO:0048515 4 0.010
regulation of cell development GO:0060284 161 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010

RFWD3 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.012
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
disease of mental health DOID:150 70 0.011
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010
sensory system disease DOID:0050155 203 0.010
eye and adnexa disease DOID:1492 150 0.010
nervous system disease DOID:863 431 0.010
eye disease DOID:5614 149 0.010