Homo sapiens

0 known processes

KDM6A

lysine (K)-specific demethylase 6A

(Aliases: UTX,DKFZp686A03225,bA386N14.2,MGC141941)

KDM6A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.368
regulation of viral process GO:0050792 103 0.293
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.255
viral process GO:0016032 146 0.202
positive regulation of viral transcription GO:0050434 13 0.194
entry into host GO:0044409 25 0.191
interspecies interaction between organisms GO:0044419 156 0.168
determination of adult lifespan GO:0008340 2 0.166
Worm
multi organism metabolic process GO:0044033 41 0.162
post embryonic development GO:0009791 2 0.157
Worm
entry into other organism involved in symbiotic interaction GO:0051828 25 0.149
modification by host of symbiont morphology or physiology GO:0051851 26 0.146
negative regulation by host of viral transcription GO:0043922 12 0.144
regulation of viral transcription GO:0046782 34 0.142
multi organism cellular process GO:0044764 156 0.136
regulation of cell growth GO:0001558 135 0.135
viral gene expression GO:0019080 35 0.128
regulation of multi organism process GO:0043900 157 0.120
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.118
regulation of cellular ketone metabolic process GO:0010565 50 0.112
modification of morphology or physiology of other organism GO:0035821 43 0.106
movement in host environment GO:0052126 25 0.103
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.102
viral life cycle GO:0019058 132 0.101
peptidyl lysine methylation GO:0018022 37 0.100
modulation by host of viral transcription GO:0043921 20 0.099
ras protein signal transduction GO:0007265 73 0.097
hindbrain development GO:0030902 3 0.097
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.096
macromolecule methylation GO:0043414 97 0.094
Worm
negative regulation of viral process GO:0048525 66 0.093
viral entry into host cell GO:0046718 24 0.092
viral transcription GO:0019083 35 0.092
chromatin modification GO:0016568 298 0.086
Human Mouse Worm
cellular macromolecular complex assembly GO:0034622 324 0.086
entry into host cell GO:0030260 25 0.081
histone lysine methylation GO:0034968 50 0.080
negative regulation of viral transcription GO:0032897 23 0.079
cellular amino acid metabolic process GO:0006520 116 0.078
regulation of growth GO:0040008 165 0.077
Worm
positive regulation of viral process GO:0048524 37 0.074
hippocampus development GO:0021766 1 0.074
positive regulation of cell growth GO:0030307 48 0.073
modulation of transcription in other organism involved in symbiotic interaction GO:0052312 20 0.070
nervous system development GO:0007399 293 0.069
Mouse
immune response GO:0006955 307 0.068
purine ribonucleoside catabolic process GO:0046130 398 0.068
negative regulation of multi organism process GO:0043901 92 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.066
protein deubiquitination GO:0016579 79 0.066
interaction with symbiont GO:0051702 26 0.065
modulation by host of symbiont transcription GO:0052472 20 0.063
cellular amine metabolic process GO:0044106 41 0.062
metencephalon development GO:0022037 2 0.060
histone modification GO:0016570 251 0.059
Human Mouse Worm
positive regulation by host of viral transcription GO:0043923 11 0.058
limbic system development GO:0021761 3 0.057
purine nucleotide catabolic process GO:0006195 405 0.056
negative regulation of cellular protein metabolic process GO:0032269 353 0.054
compound eye development GO:0048749 1 0.053
amine metabolic process GO:0009308 44 0.053
cardiovascular system development GO:0072358 262 0.053
Mouse
gtp metabolic process GO:0046039 239 0.052
cerebellum development GO:0021549 2 0.051
head development GO:0060322 108 0.050
nucleus localization GO:0051647 1 0.049
multicellular organismal aging GO:0010259 3 0.049
Worm
interaction with host GO:0051701 42 0.049
nucleoside phosphate catabolic process GO:1901292 412 0.048
purine nucleoside triphosphate metabolic process GO:0009144 412 0.047
female gamete generation GO:0007292 2 0.047
protein methylation GO:0006479 74 0.046
Worm
positive regulation of multi organism process GO:0043902 56 0.046
neural tube formation GO:0001841 3 0.046
Mouse
chromatin organization GO:0006325 351 0.045
Human Mouse Worm
cell growth GO:0016049 160 0.045
positive regulation of cellular amine metabolic process GO:0033240 7 0.045
protein acylation GO:0043543 138 0.045
peptidyl serine phosphorylation GO:0018105 101 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
organelle assembly GO:0070925 176 0.042
canonical wnt signaling pathway GO:0060070 116 0.042
Mouse
positive regulation of endopeptidase activity GO:0010950 84 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
brain development GO:0007420 97 0.041
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
carbohydrate metabolic process GO:0005975 207 0.040
regulation of defense response GO:0031347 154 0.040
neuromuscular junction development GO:0007528 3 0.039
regulation of protein complex assembly GO:0043254 147 0.037
growth GO:0040007 202 0.037
Mouse Worm
cellular component morphogenesis GO:0032989 314 0.037
positive regulation of cellular component organization GO:0051130 376 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.035
establishment of nucleus localization GO:0040023 1 0.035
small gtpase mediated signal transduction GO:0007264 78 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
histone methylation GO:0016571 60 0.035
protein alkylation GO:0008213 74 0.035
Worm
peptidyl lysine modification GO:0018205 144 0.035
dephosphorylation GO:0016311 209 0.034
endocytosis GO:0006897 159 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
cellular ketone metabolic process GO:0042180 80 0.034
nucleoside triphosphate catabolic process GO:0009143 394 0.034
single organism carbohydrate metabolic process GO:0044723 193 0.034
positive regulation of organelle organization GO:0010638 195 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
protein processing GO:0016485 226 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.033
Mouse
cytokine production GO:0001816 247 0.033
cell projection organization GO:0030030 252 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.031
regulation of transferase activity GO:0051338 355 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
oocyte development GO:0048599 1 0.031
regulation of cellular component biogenesis GO:0044087 281 0.031
response to radiation GO:0009314 151 0.030
epithelium development GO:0060429 227 0.030
Mouse
embryonic forelimb morphogenesis GO:0035115 4 0.030
organophosphate catabolic process GO:0046434 430 0.030
spermatid development GO:0007286 4 0.029
regulation of purine nucleotide metabolic process GO:1900542 264 0.029
covalent chromatin modification GO:0016569 254 0.029
Human Mouse Worm
regulation of cell morphogenesis GO:0022604 153 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
protein acetylation GO:0006473 116 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
response to abiotic stimulus GO:0009628 336 0.028
spermatid differentiation GO:0048515 4 0.028
positive regulation of hydrolase activity GO:0051345 331 0.027
embryo development GO:0009790 123 0.027
Mouse Worm
positive regulation of programmed cell death GO:0043068 249 0.027
regulation of chromosome organization GO:0033044 103 0.027
ribonucleoside catabolic process GO:0042454 406 0.026
regulation of cell cycle GO:0051726 393 0.026
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.026
positive regulation of proteolysis GO:0045862 142 0.026
dna templated transcription initiation GO:0006352 35 0.026
histone h3 k4 methylation GO:0051568 27 0.026
glycoprotein biosynthetic process GO:0009101 91 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
regulation of nucleoside metabolic process GO:0009118 209 0.025
cell development GO:0048468 328 0.025
single organism reproductive process GO:0044702 98 0.025
Worm
tube development GO:0035295 125 0.025
Mouse
positive regulation of phosphorylation GO:0042327 394 0.025
actin filament based process GO:0030029 224 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.024
ribonucleoprotein complex subunit organization GO:0071826 81 0.024
neuron projection development GO:0031175 106 0.024
protein autophosphorylation GO:0046777 123 0.024
behavior GO:0007610 112 0.024
gtp catabolic process GO:0006184 237 0.023
positive regulation of cell proliferation GO:0008284 301 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
positive regulation of peptidase activity GO:0010952 88 0.023
cellular protein catabolic process GO:0044257 261 0.023
regulation of peptidase activity GO:0052547 180 0.023
actin cytoskeleton organization GO:0030036 207 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
regulation of chromatin organization GO:1902275 56 0.022
dna packaging GO:0006323 77 0.022
forebrain regionalization GO:0021871 3 0.022
negative regulation of chromatin silencing GO:0031936 4 0.021
reactive oxygen species biosynthetic process GO:1903409 4 0.021
negative regulation of immune response GO:0050777 40 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
memory GO:0007613 3 0.021
nuclear migration GO:0007097 1 0.021
system process GO:0003008 349 0.021
Mouse
positive regulation of gtpase activity GO:0043547 166 0.020
positive regulation of growth GO:0045927 58 0.020
Worm
response to external biotic stimulus GO:0043207 261 0.020
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.020
regulation of protein kinase activity GO:0045859 289 0.020
ribonucleoprotein complex biogenesis GO:0022613 116 0.020
regulation of chromatin modification GO:1903308 51 0.020
stem cell differentiation GO:0048863 93 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
glycoprotein metabolic process GO:0009100 110 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
response to growth factor GO:0070848 205 0.019
reproductive process GO:0022414 106 0.019
Worm
purine containing compound catabolic process GO:0072523 411 0.019
response to transforming growth factor beta GO:0071559 94 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
reproductive structure development GO:0048608 55 0.019
Worm
rna processing GO:0006396 255 0.019
oogenesis GO:0048477 2 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
positive regulation of transferase activity GO:0051347 227 0.018
response to bacterium GO:0009617 144 0.018
rhythmic behavior GO:0007622 2 0.018
oocyte differentiation GO:0009994 2 0.018
regulation of gtpase activity GO:0043087 180 0.018
negative regulation of proteolysis GO:0045861 132 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
macromolecule glycosylation GO:0043413 63 0.018
nucleoside catabolic process GO:0009164 408 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
behavioral response to ethanol GO:0048149 2 0.018
anterior posterior axis specification GO:0009948 2 0.018
Mouse
protein glycosylation GO:0006486 62 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
protein k48 linked deubiquitination GO:0071108 19 0.017
cell morphogenesis GO:0000902 296 0.017
positive regulation of catabolic process GO:0009896 310 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
inner ear morphogenesis GO:0042472 4 0.017
cell morphogenesis involved in differentiation GO:0000904 144 0.017
neurotransmitter secretion GO:0007269 4 0.017
nucleotide catabolic process GO:0009166 408 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
negative regulation of protein processing GO:0010955 142 0.017
meiotic chromosome segregation GO:0045132 4 0.017
neuron development GO:0048666 113 0.017
regulation of cellular response to stress GO:0080135 244 0.017
glycosylation GO:0070085 71 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
developmental growth involved in morphogenesis GO:0060560 23 0.017
myosin filament assembly GO:0031034 2 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
regulation of protein maturation GO:1903317 150 0.017
pattern specification process GO:0007389 43 0.016
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.016
locomotory behavior GO:0007626 1 0.016
regulation of canonical wnt signaling pathway GO:0060828 88 0.016
positive regulation of chromosome organization GO:2001252 41 0.016
negative regulation of immune system process GO:0002683 136 0.016
skeletal system development GO:0001501 79 0.016
protein modification by small protein removal GO:0070646 92 0.016
regulation of intracellular transport GO:0032386 195 0.016
regulation of response to external stimulus GO:0032101 222 0.016
peptidyl lysine trimethylation GO:0018023 10 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
neuron differentiation GO:0030182 138 0.016
neuroblast proliferation GO:0007405 4 0.016
striated muscle myosin thick filament assembly GO:0071688 2 0.016
regulation of meiosis GO:0040020 3 0.016
nerve development GO:0021675 4 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
defense response to other organism GO:0098542 129 0.016
regulation of immune response GO:0050776 201 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
forelimb morphogenesis GO:0035136 4 0.015
regulation of cellular component movement GO:0051270 334 0.015
dna conformation change GO:0071103 113 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
regulation of ossification GO:0030278 58 0.015
rho protein signal transduction GO:0007266 26 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
secretion by cell GO:0032940 226 0.015
ribonucleoprotein complex assembly GO:0022618 78 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
negative regulation of protein maturation GO:1903318 142 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
regulation of proteolysis GO:0030162 293 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
cerebellar cortex development GO:0021695 1 0.015
methylation GO:0032259 106 0.015
Worm
response to hormone GO:0009725 175 0.015
epithelial cell differentiation GO:0030855 141 0.015
chemical homeostasis GO:0048878 306 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
cell projection morphogenesis GO:0048858 129 0.015
neurological system process GO:0050877 163 0.015
response to hypoxia GO:0001666 96 0.015
blastoderm segmentation GO:0007350 2 0.015
positive regulation of histone h3 k9 methylation GO:0051574 3 0.015
vesicle mediated transport GO:0016192 371 0.015
embryonic viscerocranium morphogenesis GO:0048703 1 0.015
positive regulation of histone modification GO:0031058 29 0.015
regulation of kinase activity GO:0043549 314 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
cell part morphogenesis GO:0032990 137 0.014
embryonic placenta development GO:0001892 1 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
lipid metabolic process GO:0006629 381 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
myosin filament organization GO:0031033 2 0.014
response to tumor necrosis factor GO:0034612 76 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
tube closure GO:0060606 3 0.014
Mouse
cellular homeostasis GO:0019725 196 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of map kinase activity GO:0043405 108 0.014
innate immune response GO:0045087 178 0.014
endomembrane system organization GO:0010256 196 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
wnt signaling pathway GO:0016055 156 0.013
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
developmental process involved in reproduction GO:0003006 66 0.013
Worm
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
Mouse
negative regulation of cell growth GO:0030308 83 0.013
ossification GO:0001503 121 0.013
sensory organ development GO:0007423 52 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
central nervous system development GO:0007417 123 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
negative regulation of protein modification process GO:0031400 200 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
peptidyl serine modification GO:0018209 106 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
Mouse
negative regulation of catabolic process GO:0009895 104 0.013
positive regulation of wnt signaling pathway GO:0030177 54 0.013
rna interference GO:0016246 4 0.013
hemopoiesis GO:0030097 180 0.013
negative regulation of cell cycle GO:0045786 193 0.012
regeneration GO:0031099 4 0.012
monosaccharide metabolic process GO:0005996 74 0.012
aging GO:0007568 66 0.012
Worm
positive regulation of mapk cascade GO:0043410 190 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
response to steroid hormone GO:0048545 80 0.012
circulatory system development GO:0072359 262 0.012
Mouse
forebrain development GO:0030900 26 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
actin filament organization GO:0007015 128 0.012
mitotic cell cycle GO:0000278 326 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
biological adhesion GO:0022610 331 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
cellular macromolecule catabolic process GO:0044265 380 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.012
mating GO:0007618 1 0.012
endosomal transport GO:0016197 129 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
response to other organism GO:0051707 261 0.012
protein catabolic process GO:0030163 325 0.012
heart development GO:0007507 95 0.012
Mouse
negative regulation of developmental process GO:0051093 247 0.012
Worm
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
Mouse
maintenance of location GO:0051235 112 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
chromosome segregation GO:0007059 114 0.011
regulation of protein stability GO:0031647 87 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
cellular response to decreased oxygen levels GO:0036294 51 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
neurogenesis GO:0022008 169 0.011
mitotic cell cycle process GO:1903047 286 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
cell activation GO:0001775 213 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
cellular chemical homeostasis GO:0055082 180 0.011
mapk cascade GO:0000165 288 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
apoptotic signaling pathway GO:0097190 268 0.011
neural tube closure GO:0001843 3 0.011
Mouse
regulation of dephosphorylation GO:0035303 96 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
mitotic nuclear division GO:0007067 119 0.011
microtubule based process GO:0007017 210 0.011
protein maturation GO:0051604 233 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
organelle localization GO:0051640 84 0.011
synaptic vesicle recycling GO:0036465 3 0.011
tube morphogenesis GO:0035239 95 0.011
Mouse
mrna metabolic process GO:0016071 175 0.011
response to virus GO:0009615 126 0.011
thymus development GO:0048538 3 0.011
sleep GO:0030431 2 0.011
rna splicing GO:0008380 131 0.011
positive regulation of chromatin modification GO:1903310 30 0.011
cell division GO:0051301 168 0.011
response to oxygen levels GO:0070482 100 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
generation of neurons GO:0048699 152 0.010
protein monoubiquitination GO:0006513 39 0.010
positive regulation of response to external stimulus GO:0032103 88 0.010
response to lipid GO:0033993 206 0.010
reproductive system development GO:0061458 56 0.010
Worm
regulation of cell cycle g1 s phase transition GO:1902806 42 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
metal ion transport GO:0030001 272 0.010
establishment of tissue polarity GO:0007164 3 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
establishment of organelle localization GO:0051656 59 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010

KDM6A disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.048
nervous system disease DOID:863 431 0.048
sensory system disease DOID:0050155 203 0.029
eye and adnexa disease DOID:1492 150 0.029
eye disease DOID:5614 149 0.029
neurodegenerative disease DOID:1289 102 0.023
disease of cellular proliferation DOID:14566 174 0.020
cancer DOID:162 167 0.016
organ system cancer DOID:0050686 164 0.016
immune system disease DOID:2914 155 0.013
hematopoietic system disease DOID:74 100 0.013