Homo sapiens

0 known processes

RRM2

ribonucleotide reductase M2

(Aliases: RR2M,RR2,R2)

RRM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 128 0.570
mitotic nuclear division GO:0007067 119 0.515
regulation of cell cycle GO:0051726 393 0.441
mitotic cell cycle process GO:1903047 286 0.430
mitotic cell cycle GO:0000278 326 0.368
post embryonic development GO:0009791 2 0.355
nucleoside monophosphate catabolic process GO:0009125 159 0.322
regulation of mitotic cell cycle GO:0007346 189 0.320
dna conformation change GO:0071103 113 0.304
nucleoside phosphate biosynthetic process GO:1901293 109 0.264
Yeast Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.252
nucleoside triphosphate metabolic process GO:0009141 422 0.249
chromosome segregation GO:0007059 114 0.242
ribonucleoside catabolic process GO:0042454 406 0.236
ribonucleoside triphosphate catabolic process GO:0009203 391 0.222
nucleoside phosphate catabolic process GO:1901292 412 0.220
purine nucleoside catabolic process GO:0006152 398 0.220
dna repair GO:0006281 198 0.207
ribonucleotide catabolic process GO:0009261 405 0.194
purine ribonucleoside catabolic process GO:0046130 398 0.193
regulation of cell cycle process GO:0010564 266 0.185
purine nucleoside triphosphate metabolic process GO:0009144 412 0.174
nucleoside catabolic process GO:0009164 408 0.170
ribonucleoside monophosphate catabolic process GO:0009158 158 0.166
sister chromatid segregation GO:0000819 54 0.164
negative regulation of cell cycle process GO:0010948 121 0.163
nucleoside monophosphate metabolic process GO:0009123 191 0.160
nucleotide biosynthetic process GO:0009165 109 0.159
Yeast Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.142
nucleoside triphosphate catabolic process GO:0009143 394 0.140
organelle fission GO:0048285 149 0.130
nucleotide catabolic process GO:0009166 408 0.125
microtubule based process GO:0007017 210 0.118
purine ribonucleotide catabolic process GO:0009154 404 0.115
organophosphate catabolic process GO:0046434 430 0.113
response to abiotic stimulus GO:0009628 336 0.108
cellular response to dna damage stimulus GO:0006974 379 0.103
mitotic cell cycle phase transition GO:0044772 162 0.097
positive regulation of cell cycle process GO:0090068 106 0.096
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.095
covalent chromatin modification GO:0016569 254 0.091
atp catabolic process GO:0006200 157 0.089
cytokinesis GO:0000910 96 0.087
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.087
positive regulation of programmed cell death GO:0043068 249 0.084
purine containing compound catabolic process GO:0072523 411 0.083
vesicle mediated transport GO:0016192 371 0.082
Worm
negative regulation of catalytic activity GO:0043086 335 0.077
carbohydrate derivative biosynthetic process GO:1901137 207 0.077
Yeast Mouse
regulation of chromosome segregation GO:0051983 44 0.076
cellular macromolecule catabolic process GO:0044265 380 0.073
negative regulation of programmed cell death GO:0043069 321 0.072
ribonucleoside monophosphate metabolic process GO:0009161 187 0.072
microtubule cytoskeleton organization GO:0000226 176 0.071
purine nucleotide catabolic process GO:0006195 405 0.071
positive regulation of cell cycle GO:0045787 140 0.071
chromatin modification GO:0016568 298 0.066
protein oligomerization GO:0051259 173 0.066
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 186 0.065
organophosphate biosynthetic process GO:0090407 163 0.064
Yeast Mouse
cell cycle phase transition GO:0044770 173 0.061
regulation of cellular amino acid metabolic process GO:0006521 6 0.061
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.061
embryo development GO:0009790 123 0.059
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.057
regulation of purine nucleotide metabolic process GO:1900542 264 0.057
modification dependent macromolecule catabolic process GO:0043632 212 0.055
single organism cellular localization GO:1902580 332 0.055
atp metabolic process GO:0046034 176 0.055
response to oxidative stress GO:0006979 121 0.053
dna packaging GO:0006323 77 0.052
dna replication GO:0006260 116 0.050
hematopoietic or lymphoid organ development GO:0048534 186 0.050
negative regulation of cellular component organization GO:0051129 235 0.048
ubiquitin dependent protein catabolic process GO:0006511 206 0.047
cofactor metabolic process GO:0051186 87 0.047
Yeast
protein catabolic process GO:0030163 325 0.047
multicellular organismal aging GO:0010259 3 0.046
cell development GO:0048468 328 0.045
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
mitotic sister chromatid segregation GO:0000070 53 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
response to radiation GO:0009314 151 0.043
organelle assembly GO:0070925 176 0.042
positive regulation of developmental process GO:0051094 314 0.041
negative regulation of phosphate metabolic process GO:0045936 267 0.041
positive regulation of catabolic process GO:0009896 310 0.040
oxidation reduction process GO:0055114 396 0.040
Yeast Mouse
single organism reproductive process GO:0044702 98 0.039
Worm
maintenance of location GO:0051235 112 0.039
endocytosis GO:0006897 159 0.039
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.038
cellular amine metabolic process GO:0044106 41 0.037
positive regulation of cell proliferation GO:0008284 301 0.037
cellular macromolecular complex assembly GO:0034622 324 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
protein modification by small protein conjugation GO:0032446 342 0.035
regulation of nucleoside metabolic process GO:0009118 209 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.033
regulation of cell differentiation GO:0045595 393 0.033
determination of adult lifespan GO:0008340 2 0.032
regeneration GO:0031099 4 0.032
regulation of cell division GO:0051302 116 0.032
mesenchymal cell development GO:0014031 50 0.031
deoxyribose phosphate metabolic process GO:0019692 6 0.031
response to external biotic stimulus GO:0043207 261 0.031
secretion GO:0046903 254 0.031
reproduction GO:0000003 63 0.031
Worm
cell cycle g1 s phase transition GO:0044843 80 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
response to decreased oxygen levels GO:0036293 96 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
nucleus localization GO:0051647 1 0.028
regulation of mitotic sister chromatid segregation GO:0033047 27 0.028
response to oxygen containing compound GO:1901700 369 0.028
positive regulation of apoptotic process GO:0043065 246 0.028
regulation of kinase activity GO:0043549 314 0.028
microtubule organizing center organization GO:0031023 62 0.027
meiotic chromosome segregation GO:0045132 4 0.027
ras protein signal transduction GO:0007265 73 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
purine nucleoside monophosphate catabolic process GO:0009128 158 0.027
regulation of transferase activity GO:0051338 355 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
chromatin organization GO:0006325 351 0.027
regulation of proteolysis GO:0030162 293 0.026
protein maturation GO:0051604 233 0.026
regulation of protein processing GO:0070613 150 0.026
regulation of cell cycle phase transition GO:1901987 126 0.026
dna biosynthetic process GO:0071897 40 0.026
double strand break repair GO:0006302 101 0.025
cell division GO:0051301 168 0.025
attachment of spindle microtubules to kinetochore GO:0008608 17 0.025
reproductive structure development GO:0048608 55 0.025
Worm
cell cell signaling GO:0007267 155 0.025
protein localization to nucleus GO:0034504 136 0.025
organelle localization GO:0051640 84 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
regulation of response to dna damage stimulus GO:2001020 94 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
positive regulation of mitotic cell cycle GO:0045931 60 0.024
circulatory system development GO:0072359 262 0.024
negative regulation of proteolysis GO:0045861 132 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
protein processing GO:0016485 226 0.023
cellular protein catabolic process GO:0044257 261 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
regulation of multi organism process GO:0043900 157 0.023
cell activation GO:0001775 213 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
protein autophosphorylation GO:0046777 123 0.022
cellular ketone metabolic process GO:0042180 80 0.022
negative regulation of cell cycle GO:0045786 193 0.022
regulation of mitosis GO:0007088 63 0.022
neurogenesis GO:0022008 169 0.021
oogenesis GO:0048477 2 0.021
coenzyme metabolic process GO:0006732 65 0.021
regulation of dna metabolic process GO:0051052 153 0.021
gonad development GO:0008406 34 0.021
Worm
negative regulation of phosphorylation GO:0042326 174 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.021
secretion by cell GO:0032940 226 0.021
positive regulation of cell death GO:0010942 263 0.021
protein ubiquitination GO:0016567 314 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
histone modification GO:0016570 251 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
negative regulation of cell death GO:0060548 345 0.020
regulation of cellular response to stress GO:0080135 244 0.020
chemical homeostasis GO:0048878 306 0.020
cell cycle g2 m phase transition GO:0044839 43 0.020
reproductive process GO:0022414 106 0.020
Worm
sex differentiation GO:0007548 45 0.019
Worm
negative regulation of protein maturation GO:1903318 142 0.019
oocyte differentiation GO:0009994 2 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
regulation of protein catabolic process GO:0042176 155 0.019
protein localization to organelle GO:0033365 280 0.019
apoptotic signaling pathway GO:0097190 268 0.019
dna dependent dna replication GO:0006261 44 0.018
positive regulation of cytoskeleton organization GO:0051495 83 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
immune system development GO:0002520 195 0.018
positive regulation of protein kinase activity GO:0045860 190 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
immune response GO:0006955 307 0.018
protein homooligomerization GO:0051260 100 0.017
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.017
cellular amino acid metabolic process GO:0006520 116 0.017
centrosome organization GO:0051297 58 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
regulation of peptidase activity GO:0052547 180 0.017
ribosome assembly GO:0042255 9 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.016
membrane organization GO:0061024 292 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
hemopoiesis GO:0030097 180 0.016
regulation of chromosome organization GO:0033044 103 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
mitotic dna damage checkpoint GO:0044773 28 0.015
response to other organism GO:0051707 261 0.015
female gamete generation GO:0007292 2 0.015
Worm
reproductive system development GO:0061458 56 0.015
Worm
negative regulation of catabolic process GO:0009895 104 0.015
endomembrane system organization GO:0010256 196 0.015
nervous system development GO:0007399 293 0.015
cellular homeostasis GO:0019725 196 0.015
dna recombination GO:0006310 77 0.015
cellular response to oxidative stress GO:0034599 85 0.015
positive regulation of transport GO:0051050 336 0.015
amine metabolic process GO:0009308 44 0.014
oocyte development GO:0048599 1 0.014
response to hypoxia GO:0001666 96 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
mitotic cell cycle checkpoint GO:0007093 68 0.014
cellular component morphogenesis GO:0032989 314 0.014
response to biotic stimulus GO:0009607 276 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
g1 s transition of mitotic cell cycle GO:0000082 78 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
protein tetramerization GO:0051262 47 0.013
Mouse
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
mitotic cytokinesis GO:0000281 19 0.013
mitotic sister chromatid separation GO:0051306 18 0.013
double strand break repair via homologous recombination GO:0000724 50 0.013
protein dna complex subunit organization GO:0071824 80 0.013
positive regulation of transferase activity GO:0051347 227 0.013
dephosphorylation GO:0016311 209 0.013
protein heterotetramerization GO:0051290 3 0.013
Mouse
cellular response to abiotic stimulus GO:0071214 117 0.013
negative regulation of protein processing GO:0010955 142 0.012
stem cell differentiation GO:0048863 93 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
leukocyte activation GO:0045321 164 0.012
immune effector process GO:0002252 159 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
recombinational repair GO:0000725 50 0.012
regulation of dephosphorylation GO:0035303 96 0.012
regulation of protein transport GO:0051223 213 0.012
cellular chemical homeostasis GO:0055082 180 0.012
cell cycle arrest GO:0007050 71 0.012
regulation of protein complex assembly GO:0043254 147 0.012
dna integrity checkpoint GO:0031570 71 0.012
regulation of mapk cascade GO:0043408 262 0.012
methylation GO:0032259 106 0.011
chromosome condensation GO:0030261 15 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
developmental process involved in reproduction GO:0003006 66 0.011
Worm
lymphocyte activation GO:0046649 133 0.011
oocyte maturation GO:0001556 1 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
cell projection organization GO:0030030 252 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
establishment of organelle localization GO:0051656 59 0.011
mrna metabolic process GO:0016071 175 0.011
positive regulation of kinase activity GO:0033674 204 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.010
positive regulation of organelle organization GO:0010638 195 0.010
mapk cascade GO:0000165 288 0.010
muscle structure development GO:0061061 98 0.010
regulation of meiosis GO:0040020 3 0.010
positive regulation of immune system process GO:0002684 283 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
cardiovascular system development GO:0072358 262 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010

RRM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.018
immune system disease DOID:2914 155 0.017
cancer DOID:162 167 0.010