Homo sapiens

5 known processes

TXNL1

thioredoxin-like 1

(Aliases: TRP32,TXL-1,TXNL,Txl)

TXNL1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 92 0.209
protein processing GO:0016485 226 0.202
protein maturation GO:0051604 233 0.141
determination of adult lifespan GO:0008340 2 0.130
modification dependent protein catabolic process GO:0019941 209 0.126
protein deubiquitination GO:0016579 79 0.120
proteasomal protein catabolic process GO:0010498 176 0.113
regulation of proteolysis GO:0030162 293 0.109
cellular protein catabolic process GO:0044257 261 0.098
regulation of peptidase activity GO:0052547 180 0.096
post embryonic development GO:0009791 2 0.092
regulation of cellular protein catabolic process GO:1903362 96 0.087
protein catabolic process GO:0030163 325 0.084
modification dependent macromolecule catabolic process GO:0043632 212 0.084
regulation of proteasomal protein catabolic process GO:0061136 87 0.080
multicellular organismal aging GO:0010259 3 0.080
microtubule cytoskeleton organization GO:0000226 176 0.079
cellular macromolecular complex assembly GO:0034622 324 0.078
negative regulation of protein metabolic process GO:0051248 391 0.078
cellular macromolecule catabolic process GO:0044265 380 0.072
negative regulation of hydrolase activity GO:0051346 182 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.070
regulation of protein maturation GO:1903317 150 0.070
microtubule based process GO:0007017 210 0.068
negative regulation of cellular protein metabolic process GO:0032269 353 0.067
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.060
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.059
negative regulation of protein maturation GO:1903318 142 0.059
ubiquitin dependent protein catabolic process GO:0006511 206 0.059
negative regulation of protein processing GO:0010955 142 0.057
regulation of endopeptidase activity GO:0052548 170 0.056
negative regulation of proteolysis GO:0045861 132 0.055
regulation of protein processing GO:0070613 150 0.055
negative regulation of catalytic activity GO:0043086 335 0.054
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.053
positive regulation of hydrolase activity GO:0051345 331 0.053
oogenesis GO:0048477 2 0.052
purine containing compound catabolic process GO:0072523 411 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.044
negative regulation of endopeptidase activity GO:0010951 84 0.044
purine ribonucleoside catabolic process GO:0046130 398 0.044
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
negative regulation of catabolic process GO:0009895 104 0.043
spermatid development GO:0007286 4 0.043
nucleotide catabolic process GO:0009166 408 0.043
regulation of kinase activity GO:0043549 314 0.043
purine nucleoside catabolic process GO:0006152 398 0.043
mitotic cell cycle process GO:1903047 286 0.043
nucleocytoplasmic transport GO:0006913 176 0.042
apoptotic signaling pathway GO:0097190 268 0.042
regulation of protein catabolic process GO:0042176 155 0.042
purine ribonucleotide catabolic process GO:0009154 404 0.041
purine nucleoside monophosphate catabolic process GO:0009128 158 0.041
nucleoside catabolic process GO:0009164 408 0.040
apoptotic mitochondrial changes GO:0008637 57 0.040
defense response GO:0006952 315 0.039
cellular response to dna damage stimulus GO:0006974 379 0.038
Fly
ribonucleoside catabolic process GO:0042454 406 0.037
negative regulation of peptidase activity GO:0010466 91 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
glycosyl compound catabolic process GO:1901658 413 0.036
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.036
regulation of response to external stimulus GO:0032101 222 0.035
ribonucleotide catabolic process GO:0009261 405 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
response to biotic stimulus GO:0009607 276 0.034
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
purine nucleoside monophosphate metabolic process GO:0009126 186 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.032
mitochondrion organization GO:0007005 156 0.032
positive regulation of endopeptidase activity GO:0010950 84 0.031
dna repair GO:0006281 198 0.031
locomotory behavior GO:0007626 1 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
organophosphate catabolic process GO:0046434 430 0.030
positive regulation of phosphorylation GO:0042327 394 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.029
protein localization to organelle GO:0033365 280 0.029
secretion by cell GO:0032940 226 0.028
system process GO:0003008 349 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.027
female gamete generation GO:0007292 2 0.027
negative regulation of cellular catabolic process GO:0031330 83 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.027
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
positive regulation of peptidase activity GO:0010952 88 0.027
negative regulation of cell death GO:0060548 345 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.026
positive regulation of catabolic process GO:0009896 310 0.025
meiosis i GO:0007127 4 0.025
regulation of locomotion GO:0040012 329 0.024
spermatid differentiation GO:0048515 4 0.024
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.023
neuroblast proliferation GO:0007405 4 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
cellular amino acid metabolic process GO:0006520 116 0.023
negative regulation of cellular component organization GO:0051129 235 0.022
nervous system development GO:0007399 293 0.022
cell development GO:0048468 328 0.022
positive regulation of protein transport GO:0051222 135 0.022
chemical homeostasis GO:0048878 306 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.021
response to other organism GO:0051707 261 0.021
intrinsic apoptotic signaling pathway GO:0097193 127 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
regulation of transferase activity GO:0051338 355 0.021
regulation of secretion GO:0051046 194 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
brain morphogenesis GO:0048854 1 0.020
response to external biotic stimulus GO:0043207 261 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
positive regulation of kinase activity GO:0033674 204 0.020
maintenance of location GO:0051235 112 0.020
protein k63 linked deubiquitination GO:0070536 21 0.020
response to abiotic stimulus GO:0009628 336 0.020
regulation of cell cycle GO:0051726 393 0.020
neuromuscular junction development GO:0007528 3 0.020
negative regulation of protein catabolic process GO:0042177 59 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
somatic stem cell division GO:0048103 1 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
organelle assembly GO:0070925 176 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
ion homeostasis GO:0050801 230 0.019
multi organism cellular process GO:0044764 156 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.018
oocyte development GO:0048599 1 0.018
embryo development GO:0009790 123 0.018
interspecies interaction between organisms GO:0044419 156 0.018
positive regulation of protein kinase activity GO:0045860 190 0.018
regulation of transcription factor import into nucleus GO:0042990 39 0.018
lipid metabolic process GO:0006629 381 0.018
cellular homeostasis GO:0019725 196 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.018
regulation of protein kinase activity GO:0045859 289 0.018
response to bacterium GO:0009617 144 0.017
regulation of cell differentiation GO:0045595 393 0.017
positive regulation of cell death GO:0010942 263 0.017
positive regulation of protein catabolic process GO:0045732 75 0.017
regulation of behavior GO:0050795 82 0.017
regulation of cellular response to stress GO:0080135 244 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
spinal cord development GO:0021510 4 0.016
regulation of viral process GO:0050792 103 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
protein ubiquitination GO:0016567 314 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
cellular ketone metabolic process GO:0042180 80 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.016
negative regulation of developmental process GO:0051093 247 0.016
protein dephosphorylation GO:0006470 81 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
innate immune response GO:0045087 178 0.016
regulation of protein localization GO:0032880 296 0.016
regulation of cell cycle process GO:0010564 266 0.015
head development GO:0060322 108 0.015
immune response GO:0006955 307 0.015
amine metabolic process GO:0009308 44 0.015
negative regulation of cellular protein catabolic process GO:1903363 38 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
dephosphorylation GO:0016311 209 0.015
regulation of growth GO:0040008 165 0.015
protein oligomerization GO:0051259 173 0.015
central nervous system development GO:0007417 123 0.014
negative regulation of cell cycle GO:0045786 193 0.014
negative regulation of immune system process GO:0002683 136 0.014
viral life cycle GO:0019058 132 0.014
rhythmic behavior GO:0007622 2 0.014
defense response to other organism GO:0098542 129 0.014
atp metabolic process GO:0046034 176 0.014
chemotaxis GO:0006935 157 0.014
recombinational repair GO:0000725 50 0.014
single organism cellular localization GO:1902580 332 0.014
rna interference GO:0016246 4 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.014
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.014
peptide transport GO:0015833 74 0.014
nitrogen compound transport GO:0071705 191 0.014
regulation of cellular response to growth factor stimulus GO:0090287 76 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
mitotic cell cycle GO:0000278 326 0.014
behavior GO:0007610 112 0.014
hyperosmotic response GO:0006972 4 0.014
cell cycle checkpoint GO:0000075 117 0.014
chromatin modification GO:0016568 298 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of protein complex assembly GO:0043254 147 0.013
cation transport GO:0006812 331 0.013
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of cellular component movement GO:0051270 334 0.013
lens development in camera type eye GO:0002088 2 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
positive regulation of proteolysis GO:0045862 142 0.013
cellular amine metabolic process GO:0044106 41 0.013
viral process GO:0016032 146 0.013
mapk cascade GO:0000165 288 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
cellular chemical homeostasis GO:0055082 180 0.013
gtp metabolic process GO:0046039 239 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.013
nuclear division GO:0000280 128 0.013
single organism membrane organization GO:0044802 268 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
taxis GO:0042330 157 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.013
regulation of protein import into nucleus GO:0042306 78 0.013
oocyte differentiation GO:0009994 2 0.013
amide transport GO:0042886 76 0.013
neurotransmitter secretion GO:0007269 4 0.013
cell cell signaling GO:0007267 155 0.012
epithelial to mesenchymal transition GO:0001837 48 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
sleep GO:0030431 2 0.012
glycoprotein metabolic process GO:0009100 110 0.012
cation homeostasis GO:0055080 189 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
positive regulation of transferase activity GO:0051347 227 0.012
endomembrane system organization GO:0010256 196 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
regulation of cell migration GO:0030334 289 0.012
response to oxygen containing compound GO:1901700 369 0.012
lipid biosynthetic process GO:0008610 177 0.012
rna processing GO:0006396 255 0.012
actin filament based process GO:0030029 224 0.012
anatomical structure homeostasis GO:0060249 100 0.012
translation GO:0006412 132 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
peripheral nervous system development GO:0007422 2 0.012
hindbrain development GO:0030902 3 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
regulation of secretion by cell GO:1903530 177 0.012
calcium ion transport GO:0006816 147 0.012
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
organelle fission GO:0048285 149 0.012
cytoplasmic transport GO:0016482 379 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
associative learning GO:0008306 1 0.011
monoubiquitinated histone h2a deubiquitination GO:0035522 3 0.011
cellular ion homeostasis GO:0006873 168 0.011
ncrna metabolic process GO:0034660 108 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
metal ion homeostasis GO:0055065 169 0.011
regulation of protein targeting GO:1903533 91 0.011
epithelial cell differentiation GO:0030855 141 0.011
vesicle mediated transport GO:0016192 371 0.011
regeneration GO:0031099 4 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
metal ion transport GO:0030001 272 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.011
negative regulation of protein modification process GO:0031400 200 0.011
positive regulation of transport GO:0051050 336 0.011
protein secretion GO:0009306 98 0.011
cellular cation homeostasis GO:0030003 163 0.011
ventral spinal cord development GO:0021517 1 0.011
negative regulation of locomotion GO:0040013 118 0.011
cell projection organization GO:0030030 252 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of defense response GO:0031347 154 0.011
chromosome segregation GO:0007059 114 0.011
mesenchyme development GO:0060485 59 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of neuroblast proliferation GO:1902692 3 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
rna splicing GO:0008380 131 0.011
positive regulation of immune system process GO:0002684 283 0.011
pathway restricted smad protein phosphorylation GO:0060389 38 0.011
cellular response to cytokine stimulus GO:0071345 181 0.010
response to organic cyclic compound GO:0014070 204 0.010
monoubiquitinated protein deubiquitination GO:0035520 6 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
meiotic chromosome segregation GO:0045132 4 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010
tissue regeneration GO:0042246 3 0.010
sensory perception of pain GO:0019233 4 0.010
adult locomotory behavior GO:0008344 1 0.010
cell division GO:0051301 168 0.010
epithelium development GO:0060429 227 0.010
response to nitrogen compound GO:1901698 184 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
regulation of cell motility GO:2000145 299 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
negative regulation of stem cell differentiation GO:2000737 22 0.010
histone deubiquitination GO:0016578 16 0.010
protein localization to membrane GO:0072657 160 0.010
regulation of cell growth GO:0001558 135 0.010

TXNL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.041
amino acid metabolic disorder DOID:9252 50 0.017
inherited metabolic disorder DOID:655 242 0.017
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
organ system cancer DOID:0050686 164 0.016
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
neurodegenerative disease DOID:1289 102 0.012