Homo sapiens

120 known processes

OTX2

orthodenticle homeobox 2

(Aliases: MCOPS5,MGC45000)

OTX2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.233
Mouse Worm Fly
forebrain regionalization GO:0021871 3 0.226
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.184
Fly
extraocular skeletal muscle development GO:0002074 1 0.166
specification of organ identity GO:0010092 3 0.163
organ morphogenesis GO:0009887 147 0.161
Mouse Fly
cell fate determination GO:0001709 3 0.151
Mouse
nervous system development GO:0007399 293 0.148
organ formation GO:0048645 3 0.143
regulation of cell differentiation GO:0045595 393 0.128
Fly
tube morphogenesis GO:0035239 95 0.124
Mouse
cell development GO:0048468 328 0.123
generation of neurons GO:0048699 152 0.115
circulatory system development GO:0072359 262 0.113
hindbrain development GO:0030902 3 0.112
Zebrafish Mouse
somitogenesis GO:0001756 2 0.104
Mouse
post embryonic development GO:0009791 2 0.097
segmentation GO:0035282 4 0.097
Mouse Fly
anterior posterior axis specification GO:0009948 2 0.096
Mouse
epithelium development GO:0060429 227 0.095
Zebrafish Mouse
positive regulation of developmental process GO:0051094 314 0.094
Mouse Fly
tube development GO:0035295 125 0.093
Zebrafish Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.092
Mouse
cell morphogenesis GO:0000902 296 0.084
digestive tract development GO:0048565 75 0.077
Mouse
neurogenesis GO:0022008 169 0.077
system process GO:0003008 349 0.074
Worm
central nervous system development GO:0007417 123 0.072
Zebrafish Mouse Fly
cell projection organization GO:0030030 252 0.071
neuron differentiation GO:0030182 138 0.070
metencephalon development GO:0022037 2 0.070
Mouse
stem cell differentiation GO:0048863 93 0.069
cardiovascular system development GO:0072358 262 0.069
locomotory behavior GO:0007626 1 0.067
detection of stimulus GO:0051606 85 0.065
compound eye development GO:0048749 1 0.064
Fly
cellular component morphogenesis GO:0032989 314 0.062
enzyme linked receptor protein signaling pathway GO:0007167 303 0.062
brain development GO:0007420 97 0.060
Zebrafish Mouse Fly
amine metabolic process GO:0009308 44 0.060
tissue morphogenesis GO:0048729 96 0.059
forebrain development GO:0030900 26 0.059
Mouse
embryonic morphogenesis GO:0048598 85 0.059
Mouse
regulation of cell cycle GO:0051726 393 0.058
limbic system development GO:0021761 3 0.058
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.058
adult locomotory behavior GO:0008344 1 0.057
menstrual cycle phase GO:0022601 2 0.057
positive regulation of cell differentiation GO:0045597 211 0.056
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
forebrain generation of neurons GO:0021872 3 0.055
positive regulation of cellular amine metabolic process GO:0033240 7 0.055
head development GO:0060322 108 0.054
Zebrafish Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
somatic stem cell maintenance GO:0035019 4 0.053
regulation of cellular ketone metabolic process GO:0010565 50 0.052
negative regulation of catalytic activity GO:0043086 335 0.052
formation of primary germ layer GO:0001704 42 0.052
response to oxygen containing compound GO:1901700 369 0.052
Zebrafish
negative regulation of apoptotic process GO:0043066 316 0.051
urogenital system development GO:0001655 65 0.051
neurological system process GO:0050877 163 0.049
Worm
chemical homeostasis GO:0048878 306 0.049
regulation of proteolysis GO:0030162 293 0.048
cellular amino acid metabolic process GO:0006520 116 0.048
positive regulation of cell proliferation GO:0008284 301 0.047
cardiac cell fate determination GO:0060913 3 0.047
digestive system development GO:0055123 75 0.047
Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.047
spinal cord development GO:0021510 4 0.046
ectoderm development GO:0007398 3 0.046
negative regulation of cell proliferation GO:0008285 228 0.046
response to lipid GO:0033993 206 0.045
negative regulation of developmental process GO:0051093 247 0.045
regulation of peptidase activity GO:0052547 180 0.044
epithelial tube morphogenesis GO:0060562 38 0.044
associative learning GO:0008306 1 0.043
heart formation GO:0060914 2 0.043
female gamete generation GO:0007292 2 0.043
pituitary gland development GO:0021983 2 0.042
renal system development GO:0072001 63 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.042
regulation of cell development GO:0060284 161 0.042
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.042
heart field specification GO:0003128 2 0.042
kidney development GO:0001822 53 0.041
muscle structure development GO:0061061 98 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.039
stem cell development GO:0048864 69 0.038
cellular amine metabolic process GO:0044106 41 0.037
growth GO:0040007 202 0.037
memory GO:0007613 3 0.037
neuromuscular junction development GO:0007528 3 0.036
positive regulation of cell development GO:0010720 92 0.036
Fly
negative regulation of cell differentiation GO:0045596 171 0.036
regulation of cell cycle process GO:0010564 266 0.036
regulation of nervous system development GO:0051960 88 0.036
Fly
lipid metabolic process GO:0006629 381 0.035
determination of adult lifespan GO:0008340 2 0.035
neuron projection development GO:0031175 106 0.035
sensory organ development GO:0007423 52 0.035
Zebrafish Mouse Fly
epithelial cell differentiation GO:0030855 141 0.035
regulation of neuron differentiation GO:0045664 70 0.035
Fly
cell projection morphogenesis GO:0048858 129 0.035
cellular homeostasis GO:0019725 196 0.035
cerebellum development GO:0021549 2 0.034
digestive tract morphogenesis GO:0048546 56 0.034
Mouse
cellular ketone metabolic process GO:0042180 80 0.034
secondary heart field specification GO:0003139 2 0.034
regulation of transferase activity GO:0051338 355 0.034
behavior GO:0007610 112 0.033
Worm
regulation of endopeptidase activity GO:0052548 170 0.033
posttranscriptional regulation of gene expression GO:0010608 213 0.033
positive regulation of cell cycle GO:0045787 140 0.033
negative regulation of cell death GO:0060548 345 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.033
skeletal system development GO:0001501 79 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
mitotic cell cycle GO:0000278 326 0.032
response to abiotic stimulus GO:0009628 336 0.032
Worm
peptide transport GO:0015833 74 0.032
regulation of growth GO:0040008 165 0.031
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
cellular macromolecule catabolic process GO:0044265 380 0.031
heart development GO:0007507 95 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.031
cytoplasmic transport GO:0016482 379 0.031
cell part morphogenesis GO:0032990 137 0.031
regulation of membrane potential GO:0042391 95 0.031
single organism cellular localization GO:1902580 332 0.031
positive regulation of proteolysis GO:0045862 142 0.031
nephric duct development GO:0072176 4 0.031
positive regulation of cellular component organization GO:0051130 376 0.030
cellular response to dna damage stimulus GO:0006974 379 0.030
ossification GO:0001503 121 0.030
endocrine system development GO:0035270 26 0.030
oogenesis GO:0048477 2 0.030
forebrain dorsal ventral pattern formation GO:0021798 1 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
Zebrafish
cellular response to endogenous stimulus GO:0071495 336 0.029
negative regulation of phosphorylation GO:0042326 174 0.029
actin filament based process GO:0030029 224 0.029
regulation of ossification GO:0030278 58 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.028
eye development GO:0001654 42 0.028
Zebrafish Mouse Fly
blastoderm segmentation GO:0007350 2 0.028
neuron development GO:0048666 113 0.028
inner ear morphogenesis GO:0042472 4 0.028
Mouse
endoderm development GO:0007492 33 0.028
Mouse
negative regulation of programmed cell death GO:0043069 321 0.027
regulation of mitotic cell cycle GO:0007346 189 0.027
secretion GO:0046903 254 0.027
cell cell signaling GO:0007267 155 0.027
secretion by cell GO:0032940 226 0.027
mesodermal cell fate specification GO:0007501 2 0.027
multicellular organismal aging GO:0010259 3 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
Mouse Fly
regulation of response to external stimulus GO:0032101 222 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
regulation of cell growth GO:0001558 135 0.026
positive regulation of neural precursor cell proliferation GO:2000179 2 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
mesenchymal cell differentiation GO:0048762 52 0.026
blood vessel morphogenesis GO:0048514 162 0.026
kidney morphogenesis GO:0060993 19 0.026
cell growth GO:0016049 160 0.026
nucleocytoplasmic transport GO:0006913 176 0.025
paramesonephric duct development GO:0061205 2 0.025
vasculature development GO:0001944 181 0.025
soft palate development GO:0060023 3 0.025
negative regulation of cell cycle GO:0045786 193 0.025
muscle cell fate commitment GO:0042693 4 0.025
regulation of secretion GO:0051046 194 0.025
regulation of neural precursor cell proliferation GO:2000177 4 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
Mouse Fly
embryo development GO:0009790 123 0.025
Zebrafish Mouse Worm Fly
morphogenesis of an epithelium GO:0002009 60 0.025
heart morphogenesis GO:0003007 48 0.025
taxis GO:0042330 157 0.025
biological adhesion GO:0022610 331 0.024
protein localization to organelle GO:0033365 280 0.024
response to nitrogen compound GO:1901698 184 0.024
action potential GO:0001508 34 0.024
nuclear transport GO:0051169 179 0.024
regulation of ion transmembrane transport GO:0034765 132 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
regeneration GO:0031099 4 0.024
mesonephric duct development GO:0072177 3 0.024
regulation of protein localization GO:0032880 296 0.024
embryonic epithelial tube formation GO:0001838 4 0.024
ion transmembrane transport GO:0034220 338 0.023
hard palate development GO:0060022 1 0.023
regulation of secretion by cell GO:1903530 177 0.023
neural tube patterning GO:0021532 2 0.023
Zebrafish
motor neuron axon guidance GO:0008045 2 0.023
regulation of homeostatic process GO:0032844 121 0.023
sensory organ morphogenesis GO:0090596 21 0.023
Mouse Fly
muscle system process GO:0003012 81 0.023
neuronal action potential GO:0019228 9 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
regulation of cell migration GO:0030334 289 0.022
mesodermal cell fate commitment GO:0001710 2 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
regulation of neurogenesis GO:0050767 82 0.022
Fly
membrane organization GO:0061024 292 0.022
embryonic viscerocranium morphogenesis GO:0048703 1 0.022
eye photoreceptor cell differentiation GO:0001754 2 0.022
Mouse Fly
primary neural tube formation GO:0014020 3 0.022
reproductive process GO:0022414 106 0.022
positive regulation of nervous system development GO:0051962 54 0.022
Fly
regulation of establishment of protein localization GO:0070201 242 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
nitrogen compound transport GO:0071705 191 0.022
positive regulation of cell death GO:0010942 263 0.022
embryonic camera type eye development GO:0031076 2 0.021
ion homeostasis GO:0050801 230 0.021
long term memory GO:0007616 2 0.021
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.021
metal ion transport GO:0030001 272 0.021
cell proliferation in forebrain GO:0021846 1 0.021
mesenchyme development GO:0060485 59 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
midgut development GO:0007494 1 0.021
cell division GO:0051301 168 0.021
small molecule biosynthetic process GO:0044283 157 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
cation transmembrane transport GO:0098655 238 0.021
cardiac muscle cell contraction GO:0086003 4 0.021
endodermal cell fate commitment GO:0001711 4 0.021
muscle organ development GO:0007517 56 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.021
positive regulation of transport GO:0051050 336 0.020
regulation of cell division GO:0051302 116 0.020
cellular chemical homeostasis GO:0055082 180 0.020
regulation of kinase activity GO:0043549 314 0.020
angiogenesis GO:0001525 147 0.020
negative regulation of transport GO:0051051 176 0.020
glial cell migration GO:0008347 4 0.020
protein catabolic process GO:0030163 325 0.020
menstruation GO:0042703 1 0.020
response to organic cyclic compound GO:0014070 204 0.020
transmembrane transport GO:0055085 399 0.020
ventral spinal cord development GO:0021517 1 0.020
positive regulation of endopeptidase activity GO:0010950 84 0.020
neural tube formation GO:0001841 3 0.020
regulation of cardiac muscle cell proliferation GO:0060043 4 0.020
embryonic placenta development GO:0001892 1 0.020
cell differentiation in spinal cord GO:0021515 1 0.020
sensory perception of pain GO:0019233 4 0.020
regulation of heart growth GO:0060420 4 0.020
forebrain neuron differentiation GO:0021879 3 0.020
chromatin modification GO:0016568 298 0.020
cellular response to organic cyclic compound GO:0071407 127 0.020
lipid biosynthetic process GO:0008610 177 0.019
regulation of meiotic cell cycle GO:0051445 4 0.019
gastrulation GO:0007369 51 0.019
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.019
rhythmic behavior GO:0007622 2 0.019
embryonic organ morphogenesis GO:0048562 24 0.019
Mouse
syncytium formation by plasma membrane fusion GO:0000768 2 0.019
positive regulation of neurogenesis GO:0050769 49 0.019
Fly
mapk cascade GO:0000165 288 0.019
sensory perception of smell GO:0007608 2 0.019
osteoblast differentiation GO:0001649 92 0.019
spermatid differentiation GO:0048515 4 0.019
pharynx development GO:0060465 1 0.019
single organism reproductive process GO:0044702 98 0.018
neuron projection morphogenesis GO:0048812 50 0.018
circadian behavior GO:0048512 2 0.018
chemotaxis GO:0006935 157 0.018
regulation of actin filament based process GO:0032970 141 0.018
inorganic cation transmembrane transport GO:0098662 194 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
single organism membrane organization GO:0044802 268 0.018
endodermal cell fate specification GO:0001714 4 0.018
cellular response to hormone stimulus GO:0032870 125 0.018
apoptotic signaling pathway GO:0097190 268 0.018
neuroendocrine cell differentiation GO:0061101 2 0.018
peripheral nervous system development GO:0007422 2 0.018
signal release GO:0023061 70 0.018
dephosphorylation GO:0016311 209 0.018
regulation of cardiac muscle tissue growth GO:0055021 4 0.018
cell fate commitment GO:0045165 27 0.018
Mouse Worm Fly
regulation of cell morphogenesis GO:0022604 153 0.018
response to fungus GO:0009620 4 0.018
neural crest cell development GO:0014032 3 0.018
regulation of cellular response to stress GO:0080135 244 0.018
monovalent inorganic cation transport GO:0015672 128 0.017
sensory perception GO:0007600 103 0.017
Worm
positive regulation of phosphorylation GO:0042327 394 0.017
pericardium development GO:0060039 2 0.017
detection of chemical stimulus GO:0009593 55 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
sex determination GO:0007530 3 0.017
regulation of meiosis GO:0040020 3 0.017
vesicle mediated transport GO:0016192 371 0.017
negative regulation of cell development GO:0010721 48 0.017
regulation of protein transport GO:0051223 213 0.017
cation transport GO:0006812 331 0.017
nerve development GO:0021675 4 0.017
salivary gland morphogenesis GO:0007435 4 0.017
thymus development GO:0048538 3 0.017
tripartite regional subdivision GO:0007351 2 0.017
striated muscle contraction GO:0006941 52 0.017
regulation of epithelial cell differentiation involved in kidney development GO:2000696 4 0.017
neuroblast proliferation GO:0007405 4 0.017
protein localization to nucleus GO:0034504 136 0.017
cell cycle phase transition GO:0044770 173 0.017
regulation of transmembrane transport GO:0034762 139 0.017
regulation of intracellular transport GO:0032386 195 0.017
immune response GO:0006955 307 0.017
immune system development GO:0002520 195 0.017
protein targeting GO:0006605 187 0.017
negative regulation of transferase activity GO:0051348 124 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
oocyte differentiation GO:0009994 2 0.016
interspecies interaction between organisms GO:0044419 156 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
cellular protein catabolic process GO:0044257 261 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
myoblast fusion GO:0007520 1 0.016
gastrulation with mouth forming second GO:0001702 1 0.016
Mouse
response to organonitrogen compound GO:0010243 156 0.016
viral life cycle GO:0019058 132 0.016
neurotransmitter secretion GO:0007269 4 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
amide transport GO:0042886 76 0.016
response to wounding GO:0009611 168 0.016
cation homeostasis GO:0055080 189 0.016
reproductive system development GO:0061458 56 0.016
mesenchymal cell development GO:0014031 50 0.016
response to external biotic stimulus GO:0043207 261 0.016
multicellular organismal signaling GO:0035637 34 0.016
protein oligomerization GO:0051259 173 0.016
cranial nerve development GO:0021545 4 0.016
negative regulation of cell growth GO:0030308 83 0.016
hormone secretion GO:0046879 65 0.016
hemopoiesis GO:0030097 180 0.016
startle response GO:0001964 3 0.016
lung alveolus development GO:0048286 4 0.016
cardiac muscle contraction GO:0060048 34 0.016
oocyte development GO:0048599 1 0.016
blood vessel development GO:0001568 172 0.015
negative regulation of kidney development GO:0090185 2 0.015
spermatid development GO:0007286 4 0.015
defense response GO:0006952 315 0.015
kidney epithelium development GO:0072073 25 0.015
negative regulation of protein processing GO:0010955 142 0.015
regulation of mapk cascade GO:0043408 262 0.015
negative regulation of protein modification process GO:0031400 200 0.015
organelle assembly GO:0070925 176 0.015
negative regulation of growth GO:0045926 97 0.015
response to cytokine GO:0034097 232 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
response to other organism GO:0051707 261 0.015
oxidation reduction process GO:0055114 396 0.015
carbohydrate metabolic process GO:0005975 207 0.015
regulation of cellular component movement GO:0051270 334 0.015
regulation of protein kinase activity GO:0045859 289 0.015
rna processing GO:0006396 255 0.015
negative regulation of mitotic cell cycle GO:0045930 102 0.015
mitotic cell cycle process GO:1903047 286 0.015
renal sodium ion absorption GO:0070294 2 0.015
hippocampus development GO:0021766 1 0.015
regulation of stem cell differentiation GO:2000736 56 0.015
regionalization GO:0003002 29 0.015
Zebrafish Mouse Fly
regulation of canonical wnt signaling pathway GO:0060828 88 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
response to radiation GO:0009314 151 0.015
protein ubiquitination GO:0016567 314 0.015
innate immune response GO:0045087 178 0.015
retinal ganglion cell axon guidance GO:0031290 2 0.015
intracellular protein transport GO:0006886 270 0.015
axis elongation GO:0003401 4 0.015
covalent chromatin modification GO:0016569 254 0.015
tube closure GO:0060606 3 0.015
canonical wnt signaling pathway GO:0060070 116 0.015
nephron epithelium development GO:0072009 23 0.015
intracellular receptor signaling pathway GO:0030522 104 0.014
response to light stimulus GO:0009416 87 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
nephron development GO:0072006 30 0.014
wnt signaling pathway GO:0016055 156 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
response to axon injury GO:0048678 1 0.014
regulation of osteoblast differentiation GO:0045667 38 0.014
dna repair GO:0006281 198 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
positive regulation of peptidase activity GO:0010952 88 0.014
pattern specification process GO:0007389 43 0.014
Zebrafish Mouse Fly
positive regulation of catabolic process GO:0009896 310 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
developmental process involved in reproduction GO:0003006 66 0.014
protein import GO:0017038 130 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
sodium ion transmembrane transport GO:0035725 59 0.014
convergent extension GO:0060026 1 0.014
post embryonic organ development GO:0048569 1 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.014
mating GO:0007618 1 0.014
muscle contraction GO:0006936 73 0.014
negative regulation of proteolysis GO:0045861 132 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regulation of peptide transport GO:0090087 62 0.014
transmission of nerve impulse GO:0019226 11 0.014
translation GO:0006412 132 0.013
actin mediated cell contraction GO:0070252 12 0.013
regulation of multi organism process GO:0043900 157 0.013
positive regulation of organelle organization GO:0010638 195 0.013
cell differentiation in hindbrain GO:0021533 1 0.013
visual behavior GO:0007632 2 0.013
cellular response to lipid GO:0071396 127 0.013
behavioral response to ethanol GO:0048149 2 0.013
endoderm formation GO:0001706 33 0.013
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
protein import into nucleus GO:0006606 104 0.013
reproductive structure development GO:0048608 55 0.013
cell cycle arrest GO:0007050 71 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.013
protein localization to membrane GO:0072657 160 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.013
cell adhesion GO:0007155 325 0.013
protein targeting to nucleus GO:0044744 104 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
anion transport GO:0006820 161 0.013
regulation of cell motility GO:2000145 299 0.013
nephron morphogenesis GO:0072028 15 0.013
sleep GO:0030431 2 0.013
response to growth factor GO:0070848 205 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
cellular component disassembly GO:0022411 92 0.013
positive regulation of neuron differentiation GO:0045666 40 0.013
Fly
regulation of hormone secretion GO:0046883 57 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.013
mitochondrion organization GO:0007005 156 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
alcohol metabolic process GO:0006066 114 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.013
positive regulation of gliogenesis GO:0014015 4 0.013
neuron projection regeneration GO:0031102 1 0.013
regulation of cytoskeleton organization GO:0051493 177 0.012
neural tube closure GO:0001843 3 0.012
signal transduction involved in regulation of gene expression GO:0023019 1 0.012
negative regulation of kinase activity GO:0033673 106 0.012
distal tubule development GO:0072017 4 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
organophosphate catabolic process GO:0046434 430 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of response to wounding GO:1903034 101 0.012
neural crest cell migration GO:0001755 2 0.012
regulation of body fluid levels GO:0050878 99 0.012
tissue regeneration GO:0042246 3 0.012
multi organism cellular process GO:0044764 156 0.012
regulation of postsynaptic membrane potential GO:0060078 1 0.012
regulation of ion transport GO:0043269 189 0.012
regulation of locomotion GO:0040012 329 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
nephron epithelium morphogenesis GO:0072088 15 0.012
lung cell differentiation GO:0060479 1 0.012
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 4 0.012
protein localization to plasma membrane GO:0072659 93 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
telencephalon development GO:0021537 17 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
mesoderm development GO:0007498 14 0.012

OTX2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.081
eye and adnexa disease DOID:1492 150 0.081
nervous system disease DOID:863 431 0.081
eye disease DOID:5614 149 0.081
retinal disease DOID:5679 118 0.026
Human
disease of metabolism DOID:0014667 295 0.023
central nervous system disease DOID:331 186 0.019
retinal degeneration DOID:8466 89 0.016
Human
neurodegenerative disease DOID:1289 102 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
muscular disease DOID:0080000 114 0.013
musculoskeletal system disease DOID:17 223 0.013
muscle tissue disease DOID:66 113 0.013