Homo sapiens

0 known processes

SIRPA

signal-regulatory protein alpha

(Aliases: CD172A,PTPNS1,SIRP,P84,MYD-1,MFR,BIT,SHPS1)

SIRPA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 315 0.440
vesicle mediated transport GO:0016192 371 0.268
Mouse
positive regulation of cell proliferation GO:0008284 301 0.262
Human
chemical homeostasis GO:0048878 306 0.250
cell development GO:0048468 328 0.243
lipid metabolic process GO:0006629 381 0.227
biological adhesion GO:0022610 331 0.208
Human Mouse
response to biotic stimulus GO:0009607 276 0.184
small gtpase mediated signal transduction GO:0007264 78 0.171
regulation of cell differentiation GO:0045595 393 0.153
regulation of anatomical structure morphogenesis GO:0022603 286 0.139
cellular response to oxygen containing compound GO:1901701 276 0.138
response to oxygen containing compound GO:1901700 369 0.134
cellular ion homeostasis GO:0006873 168 0.128
negative regulation of apoptotic process GO:0043066 316 0.128
organic hydroxy compound transport GO:0015850 63 0.123
circulatory system development GO:0072359 262 0.117
nervous system development GO:0007399 293 0.117
cell activation GO:0001775 213 0.115
Human
response to lipid GO:0033993 206 0.112
ras protein signal transduction GO:0007265 73 0.106
response to hormone GO:0009725 175 0.106
regulation of cell migration GO:0030334 289 0.106
cellular amine metabolic process GO:0044106 41 0.105
cation transport GO:0006812 331 0.100
cell adhesion GO:0007155 325 0.098
Human Mouse
cytokine production GO:0001816 247 0.097
response to cytokine GO:0034097 232 0.094
negative regulation of multicellular organismal process GO:0051241 317 0.094
negative regulation of cell death GO:0060548 345 0.093
regulation of cellular component movement GO:0051270 334 0.093
negative regulation of catalytic activity GO:0043086 335 0.092
oogenesis GO:0048477 2 0.092
actin cytoskeleton organization GO:0030036 207 0.091
Mouse
cellular chemical homeostasis GO:0055082 180 0.090
leukocyte activation GO:0045321 164 0.090
Human
regulation of cell adhesion GO:0030155 166 0.090
Human
negative regulation of alpha beta t cell activation GO:0046636 3 0.090
positive regulation of hydrolase activity GO:0051345 331 0.088
regulation of cellular amino acid metabolic process GO:0006521 6 0.087
regulation of erk1 and erk2 cascade GO:0070372 99 0.085
cardiovascular system development GO:0072358 262 0.085
metal ion transport GO:0030001 272 0.084
positive regulation of cellular component organization GO:0051130 376 0.083
Mouse
regulation of cell motility GO:2000145 299 0.082
mapk cascade GO:0000165 288 0.080
immune response GO:0006955 307 0.079
response to abiotic stimulus GO:0009628 336 0.078
ribonucleotide catabolic process GO:0009261 405 0.078
immune system development GO:0002520 195 0.077
Mouse
innate immune response GO:0045087 178 0.073
negative regulation of cell proliferation GO:0008285 228 0.073
positive regulation of cell differentiation GO:0045597 211 0.072
positive regulation of cellular amine metabolic process GO:0033240 7 0.071
ion homeostasis GO:0050801 230 0.069
purine ribonucleotide catabolic process GO:0009154 404 0.069
metal ion homeostasis GO:0055065 169 0.068
positive regulation of protein phosphorylation GO:0001934 313 0.068
positive regulation of synaptic transmission GO:0050806 4 0.068
response to other organism GO:0051707 261 0.068
enzyme linked receptor protein signaling pathway GO:0007167 303 0.068
negative regulation of immune system process GO:0002683 136 0.067
positive regulation of cellular catabolic process GO:0031331 284 0.066
regulation of cytokine production GO:0001817 232 0.066
regulation of cell cycle GO:0051726 393 0.066
regulation of establishment of protein localization GO:0070201 242 0.065
regulation of response to external stimulus GO:0032101 222 0.063
positive regulation of transport GO:0051050 336 0.063
Mouse
cell morphogenesis GO:0000902 296 0.063
regulation of locomotion GO:0040012 329 0.062
negative regulation of protein metabolic process GO:0051248 391 0.062
female gamete generation GO:0007292 2 0.062
angiogenesis GO:0001525 147 0.061
regulation of mapk cascade GO:0043408 262 0.061
immune response regulating signaling pathway GO:0002764 97 0.061
neurogenesis GO:0022008 169 0.061
purine nucleotide catabolic process GO:0006195 405 0.061
regulation of dendritic cell apoptotic process GO:2000668 4 0.061
peptidyl tyrosine modification GO:0018212 170 0.060
regulation of protein localization GO:0032880 296 0.059
nucleoside triphosphate catabolic process GO:0009143 394 0.059
negative regulation of programmed cell death GO:0043069 321 0.058
cellular cation homeostasis GO:0030003 163 0.058
platelet formation GO:0030220 4 0.058
actin filament based process GO:0030029 224 0.057
Mouse
gtp catabolic process GO:0006184 237 0.057
signal transduction by phosphorylation GO:0023014 297 0.057
cellular metal ion homeostasis GO:0006875 146 0.057
positive regulation of cell motility GO:2000147 177 0.056
response to organonitrogen compound GO:0010243 156 0.056
small molecule biosynthetic process GO:0044283 157 0.055
purine ribonucleoside catabolic process GO:0046130 398 0.055
regulation of kinase activity GO:0043549 314 0.054
blood vessel development GO:0001568 172 0.053
cellular amino acid metabolic process GO:0006520 116 0.053
positive regulation of apoptotic process GO:0043065 246 0.053
inorganic ion transmembrane transport GO:0098660 231 0.053
cellular response to endogenous stimulus GO:0071495 336 0.053
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.053
rho protein signal transduction GO:0007266 26 0.052
inflammatory response GO:0006954 79 0.052
regulation of cellular component biogenesis GO:0044087 281 0.052
monocarboxylic acid metabolic process GO:0032787 185 0.052
regulation of synaptic plasticity GO:0048167 3 0.052
regulation of transferase activity GO:0051338 355 0.052
cellular ketone metabolic process GO:0042180 80 0.051
cation homeostasis GO:0055080 189 0.051
cellular component morphogenesis GO:0032989 314 0.050
secretion GO:0046903 254 0.050
cellular response to growth factor stimulus GO:0071363 197 0.050
regulation of secretion by cell GO:1903530 177 0.050
purine containing compound catabolic process GO:0072523 411 0.050
hematopoietic or lymphoid organ development GO:0048534 186 0.049
Mouse
alcohol metabolic process GO:0006066 114 0.049
positive regulation of catabolic process GO:0009896 310 0.048
single organismal cell cell adhesion GO:0016337 148 0.048
Human
ribonucleoside catabolic process GO:0042454 406 0.048
purine nucleoside triphosphate catabolic process GO:0009146 392 0.048
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
regulation of secretion GO:0051046 194 0.048
cell type specific apoptotic process GO:0097285 125 0.048
single organism cellular localization GO:1902580 332 0.047
positive regulation of kinase activity GO:0033674 204 0.047
organophosphate catabolic process GO:0046434 430 0.047
regulation of vesicle mediated transport GO:0060627 130 0.047
Mouse
regulation of defense response GO:0031347 154 0.047
guanosine containing compound catabolic process GO:1901069 239 0.046
positive regulation of immune response GO:0050778 159 0.046
regulation of cellular ketone metabolic process GO:0010565 50 0.046
regulation of proteolysis GO:0030162 293 0.046
positive regulation of cellular component movement GO:0051272 181 0.046
single organism membrane organization GO:0044802 268 0.046
positive regulation of transferase activity GO:0051347 227 0.046
response to bacterium GO:0009617 144 0.045
nucleotide catabolic process GO:0009166 408 0.045
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.045
guanosine containing compound metabolic process GO:1901068 244 0.045
mitotic cell cycle process GO:1903047 286 0.045
positive regulation of cell adhesion GO:0045785 84 0.044
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.044
epithelium development GO:0060429 227 0.044
anatomical structure formation involved in morphogenesis GO:0048646 284 0.044
regulation of cellular response to stress GO:0080135 244 0.043
negative regulation of myeloid cell differentiation GO:0045638 42 0.043
post embryonic development GO:0009791 2 0.043
blood vessel morphogenesis GO:0048514 162 0.043
system process GO:0003008 349 0.043
cellular homeostasis GO:0019725 196 0.042
memory GO:0007613 3 0.042
cellular lipid metabolic process GO:0044255 303 0.042
myeloid cell differentiation GO:0030099 117 0.042
nucleoside catabolic process GO:0009164 408 0.042
regulation of protein transport GO:0051223 213 0.042
divalent inorganic cation homeostasis GO:0072507 136 0.042
protein maturation GO:0051604 233 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.042
erk1 and erk2 cascade GO:0070371 104 0.041
positive regulation of locomotion GO:0040017 186 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
regulation of cell development GO:0060284 161 0.041
multicellular organismal aging GO:0010259 3 0.041
leukocyte migration GO:0050900 107 0.041
negative regulation of protein modification process GO:0031400 200 0.041
purine ribonucleoside metabolic process GO:0046128 437 0.040
myeloid leukocyte activation GO:0002274 34 0.040
regulation of reactive oxygen species metabolic process GO:2000377 41 0.040
secretion by cell GO:0032940 226 0.040
response to oxidative stress GO:0006979 121 0.040
cellular macromolecule catabolic process GO:0044265 380 0.040
mitotic cell cycle GO:0000278 326 0.039
protein modification by small protein conjugation GO:0032446 342 0.039
central nervous system development GO:0007417 123 0.038
negative regulation of tumor necrosis factor biosynthetic process GO:0042536 3 0.038
epithelial cell differentiation GO:0030855 141 0.038
negative regulation of protein phosphorylation GO:0001933 140 0.038
cytoplasmic transport GO:0016482 379 0.038
vasculature development GO:0001944 181 0.037
regulation of nucleotide catabolic process GO:0030811 205 0.037
protein catabolic process GO:0030163 325 0.037
calcium ion homeostasis GO:0055074 122 0.037
regulation of gtp catabolic process GO:0033124 180 0.037
stress activated protein kinase signaling cascade GO:0031098 94 0.037
positive regulation of cell migration GO:0030335 172 0.037
interleukin 12 secretion GO:0072610 1 0.036
negative regulation of cellular component organization GO:0051129 235 0.036
reproductive process GO:0022414 106 0.036
gtp metabolic process GO:0046039 239 0.036
response to wounding GO:0009611 168 0.036
protein oligomerization GO:0051259 173 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.036
leukocyte differentiation GO:0002521 98 0.036
cell cell signaling GO:0007267 155 0.035
cellular response to cytokine stimulus GO:0071345 181 0.035
segmentation GO:0035282 4 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
cell growth GO:0016049 160 0.035
amine metabolic process GO:0009308 44 0.035
ion transmembrane transport GO:0034220 338 0.035
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.035
regulation of ras protein signal transduction GO:0046578 155 0.035
organic hydroxy compound metabolic process GO:1901615 147 0.034
positive regulation of nucleotide metabolic process GO:0045981 230 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.034
positive regulation of developmental process GO:0051094 314 0.034
positive regulation of map kinase activity GO:0043406 80 0.034
hemopoiesis GO:0030097 180 0.034
Mouse
neuron development GO:0048666 113 0.034
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
regulation of calcium ion transport GO:0051924 79 0.034
regulation of intracellular transport GO:0032386 195 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
positive regulation of nucleotide catabolic process GO:0030813 185 0.033
regulation of membrane potential GO:0042391 95 0.033
regulation of lymphocyte proliferation GO:0050670 64 0.033
head development GO:0060322 108 0.033
protein processing GO:0016485 226 0.033
regulation of map kinase activity GO:0043405 108 0.033
regulation of protein serine threonine kinase activity GO:0071900 179 0.032
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
regulation of peptidase activity GO:0052547 180 0.032
negative regulation of intracellular signal transduction GO:1902532 183 0.032
positive regulation of phosphorylation GO:0042327 394 0.032
regulation of nucleoside metabolic process GO:0009118 209 0.032
oocyte differentiation GO:0009994 2 0.032
determination of adult lifespan GO:0008340 2 0.032
regulation of growth GO:0040008 165 0.032
blastoderm segmentation GO:0007350 2 0.032
regulation of protein kinase activity GO:0045859 289 0.032
regulation of interferon beta secretion GO:0035547 1 0.032
cytokine secretion GO:0050663 64 0.031
regulation of protein secretion GO:0050708 86 0.031
response to organic cyclic compound GO:0014070 204 0.031
neuromuscular junction development GO:0007528 3 0.031
membrane organization GO:0061024 292 0.031
Mouse
myeloid leukocyte differentiation GO:0002573 60 0.031
reactive oxygen species biosynthetic process GO:1903409 4 0.031
positive regulation of immune system process GO:0002684 283 0.030
Human
negative regulation of transport GO:0051051 176 0.030
regulation of ion transport GO:0043269 189 0.030
organophosphate biosynthetic process GO:0090407 163 0.030
intracellular protein transport GO:0006886 270 0.030
regulation of lipid metabolic process GO:0019216 96 0.030
cellular calcium ion homeostasis GO:0006874 117 0.030
positive regulation of cell development GO:0010720 92 0.030
positive regulation of protein kinase activity GO:0045860 190 0.030
purine nucleoside triphosphate metabolic process GO:0009144 412 0.030
positive regulation of cytokine production GO:0001819 167 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
positive regulation of ras gtpase activity GO:0032320 117 0.030
protein autophosphorylation GO:0046777 123 0.029
cell projection organization GO:0030030 252 0.029
regulation of endopeptidase activity GO:0052548 170 0.029
nucleocytoplasmic transport GO:0006913 176 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.029
dephosphorylation GO:0016311 209 0.029
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.029
type i interferon secretion GO:0072641 1 0.028
negative regulation of phosphorylation GO:0042326 174 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
neuron differentiation GO:0030182 138 0.028
cytosolic calcium ion homeostasis GO:0051480 89 0.028
regulation of leukocyte activation GO:0002694 115 0.028
Human
nucleoside phosphate catabolic process GO:1901292 412 0.028
response to growth factor GO:0070848 205 0.028
positive regulation of cell death GO:0010942 263 0.028
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
cellular response to organonitrogen compound GO:0071417 124 0.028
response to virus GO:0009615 126 0.028
positive regulation of gtpase activity GO:0043547 166 0.028
response to nitrogen compound GO:1901698 184 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
regulation of metal ion transport GO:0010959 120 0.027
positive regulation of gtp catabolic process GO:0033126 166 0.027
anion transport GO:0006820 161 0.027
cellular response to lipid GO:0071396 127 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
regulation of cell projection organization GO:0031344 107 0.027
generation of neurons GO:0048699 152 0.027
neurological system process GO:0050877 163 0.027
epithelium migration GO:0090132 119 0.027
cd8 positive alpha beta t cell activation GO:0036037 3 0.027
regulation of immune response GO:0050776 201 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
lipid biosynthetic process GO:0008610 177 0.026
brain development GO:0007420 97 0.026
nitrogen compound transport GO:0071705 191 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
endocytosis GO:0006897 159 0.026
Mouse
single organism cell adhesion GO:0098602 179 0.026
Human
positive regulation of protein transport GO:0051222 135 0.025
negative regulation of developmental process GO:0051093 247 0.025
rhythmic behavior GO:0007622 2 0.025
regulation of ras gtpase activity GO:0032318 128 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
regulation of myeloid cell differentiation GO:0045637 81 0.025
divalent inorganic cation transport GO:0072511 158 0.025
response to external biotic stimulus GO:0043207 261 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.024
positive regulation of proteolysis GO:0045862 142 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
regulation of innate immune response GO:0045088 97 0.024
cellular response to hormone stimulus GO:0032870 125 0.024
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.024
nuclear transport GO:0051169 179 0.024
regulation of cytoplasmic transport GO:1903649 149 0.024
regulation of vasculature development GO:1901342 97 0.024
regulation of mononuclear cell proliferation GO:0032944 65 0.024
calcium ion transport GO:0006816 147 0.023
cellular response to abiotic stimulus GO:0071214 117 0.023
cellular response to organic cyclic compound GO:0071407 127 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
compound eye development GO:0048749 1 0.023
response to inorganic substance GO:0010035 127 0.023
regulation of cytokine secretion GO:0050707 57 0.023
positive regulation of leukocyte activation GO:0002696 80 0.023
Human
chemotaxis GO:0006935 157 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
growth GO:0040007 202 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
associative learning GO:0008306 1 0.022
defense response to virus GO:0051607 71 0.022
regulation of protein maturation GO:1903317 150 0.022
response to drug GO:0042493 81 0.022
divalent metal ion transport GO:0070838 152 0.022
inositol lipid mediated signaling GO:0048017 55 0.022
positive regulation of cell substrate adhesion GO:0010811 37 0.022
single organism reproductive process GO:0044702 98 0.022
spermatid development GO:0007286 4 0.022
positive regulation of lymphocyte activation GO:0051251 73 0.022
Human
regulation of neuron apoptotic process GO:0043523 35 0.021
protein targeting GO:0006605 187 0.021
cellular response to nitrogen compound GO:1901699 144 0.021
negative regulation of peptidase activity GO:0010466 91 0.021
apoptotic signaling pathway GO:0097190 268 0.021
regeneration GO:0031099 4 0.021
negative regulation of cell cycle GO:0045786 193 0.021
locomotory behavior GO:0007626 1 0.021
regulation of cell substrate adhesion GO:0010810 68 0.021
activation of protein kinase activity GO:0032147 90 0.021
positive regulation of cytolysis GO:0045919 3 0.021
cell activation involved in immune response GO:0002263 30 0.021
negative regulation of cell differentiation GO:0045596 171 0.021
ameboidal type cell migration GO:0001667 135 0.021
cation transmembrane transport GO:0098655 238 0.021
epithelial cell proliferation GO:0050673 128 0.021
anterior posterior axis specification GO:0009948 2 0.021
negative regulation of transferase activity GO:0051348 124 0.021
dendritic cell apoptotic process GO:0097048 4 0.021
carbohydrate metabolic process GO:0005975 207 0.021
serotonin transport GO:0006837 3 0.021
maintenance of location GO:0051235 112 0.020
cytokine production involved in immune response GO:0002367 27 0.020
protein ubiquitination GO:0016567 314 0.020
embryo development GO:0009790 123 0.020
oocyte development GO:0048599 1 0.020
regulation of protein processing GO:0070613 150 0.020
protein secretion GO:0009306 98 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
cellular response to peptide GO:1901653 59 0.020
developmental programmed cell death GO:0010623 3 0.020
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
cell projection assembly GO:0030031 126 0.020
negative regulation of leukocyte activation GO:0002695 26 0.020
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.020
cellular protein catabolic process GO:0044257 261 0.020
synaptic transmission GO:0007268 61 0.020
long term memory GO:0007616 2 0.019
muscle contraction GO:0006936 73 0.019
negative regulation of dendritic cell differentiation GO:2001199 2 0.019
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
regulation of neuron differentiation GO:0045664 70 0.019
regulation of cell activation GO:0050865 125 0.019
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
regulation of leukocyte differentiation GO:1902105 61 0.019
neuron projection development GO:0031175 106 0.019
cell cycle phase transition GO:0044770 173 0.019
cell junction assembly GO:0034329 67 0.019
regulation of rho gtpase activity GO:0032319 66 0.018
response to alcohol GO:0097305 64 0.018
negative regulation of cytokine production GO:0001818 82 0.018
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.018
spermatid differentiation GO:0048515 4 0.018
midbrain development GO:0030901 45 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
regulation of leukocyte proliferation GO:0070663 67 0.018
positive regulation of rho gtpase activity GO:0032321 56 0.018
activation of immune response GO:0002253 114 0.018
behavior GO:0007610 112 0.018
cell projection morphogenesis GO:0048858 129 0.018
gamma delta t cell activation GO:0046629 3 0.018
negative regulation of immune effector process GO:0002698 38 0.018
lipid localization GO:0010876 106 0.018
protein localization to organelle GO:0033365 280 0.018
response to molecule of bacterial origin GO:0002237 82 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.018
tripartite regional subdivision GO:0007351 2 0.017
sequestering of metal ion GO:0051238 24 0.017
morphogenesis of an epithelium GO:0002009 60 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
adult locomotory behavior GO:0008344 1 0.017
epithelial cell development GO:0002064 34 0.017
plasma membrane organization GO:0007009 115 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
negative regulation of cell activation GO:0050866 33 0.017
glycerolipid metabolic process GO:0046486 107 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
neuron death GO:0070997 65 0.017
neurotransmitter secretion GO:0007269 4 0.017
negative regulation of apoptotic signaling pathway GO:2001234 97 0.017
organic hydroxy compound biosynthetic process GO:1901617 71 0.017
cell part morphogenesis GO:0032990 137 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
negative regulation of protein processing GO:0010955 142 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
response to lithium ion GO:0010226 2 0.016
response to hypoxia GO:0001666 96 0.016
negative regulation of cell development GO:0010721 48 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
fc receptor mediated inhibitory signaling pathway GO:0002774 2 0.016
cell substrate adhesion GO:0031589 132 0.016
Mouse
regulation of system process GO:0044057 101 0.016
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.016
negative regulation of interferon beta production GO:0032688 4 0.016
cell chemotaxis GO:0060326 112 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
regulation of gamma delta t cell activation involved in immune response GO:2001191 1 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
myeloid dendritic cell activation GO:0001773 4 0.016
positive regulation of cell cycle GO:0045787 140 0.016
response to hydrogen peroxide GO:0042542 40 0.016
cell junction organization GO:0034330 79 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
anatomical structure homeostasis GO:0060249 100 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
response to tumor necrosis factor GO:0034612 76 0.016
negative regulation of secretion GO:0051048 58 0.016
regulation of endocytosis GO:0030100 72 0.016
Mouse
response to metal ion GO:0010038 84 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
negative regulation of defense response GO:0031348 47 0.015
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.015
multicellular organismal homeostasis GO:0048871 67 0.015
muscle system process GO:0003012 81 0.015
circadian behavior GO:0048512 2 0.015
negative regulation of cell adhesion GO:0007162 64 0.015
antigen processing and presentation GO:0019882 33 0.015
tissue morphogenesis GO:0048729 96 0.015
regulation of anatomical structure size GO:0090066 101 0.015
transmembrane transport GO:0055085 399 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
leukocyte proliferation GO:0070661 74 0.015
positive regulation of epithelial cell proliferation GO:0050679 65 0.015
defense response to other organism GO:0098542 129 0.015
cellular response to peptide hormone stimulus GO:0071375 56 0.015
g protein coupled receptor signaling pathway GO:0007186 207 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
activation of mapk activity GO:0000187 45 0.015
positive regulation of cell activation GO:0050867 81 0.015
Human
glycerophospholipid metabolic process GO:0006650 84 0.015
response to extracellular stimulus GO:0009991 85 0.015
positive regulation of leukocyte proliferation GO:0070665 48 0.015
regulation of protein catabolic process GO:0042176 155 0.015
regulation of cell shape GO:0008360 48 0.015

SIRPA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.077
inherited metabolic disorder DOID:655 242 0.048
immune system disease DOID:2914 155 0.042
musculoskeletal system disease DOID:17 223 0.036
central nervous system disease DOID:331 186 0.027
nervous system disease DOID:863 431 0.027
connective tissue disease DOID:65 109 0.026
sensory system disease DOID:0050155 203 0.026
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.022
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
retinal disease DOID:5679 118 0.016
bone disease DOID:0080001 88 0.015