Homo sapiens

52 known processes

SPOPL

speckle-type POZ protein-like

(Aliases: FLJ53775)

SPOPL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 6 0.133
lipid metabolic process GO:0006629 381 0.083
regulation of cellular ketone metabolic process GO:0010565 50 0.081
tor signaling GO:0031929 39 0.076
cellular response to endogenous stimulus GO:0071495 336 0.067
amine metabolic process GO:0009308 44 0.066
ras protein signal transduction GO:0007265 73 0.066
response to growth factor GO:0070848 205 0.063
cellular amino acid metabolic process GO:0006520 116 0.062
cellular ketone metabolic process GO:0042180 80 0.059
cellular amine metabolic process GO:0044106 41 0.059
cellular lipid metabolic process GO:0044255 303 0.057
neuromuscular junction development GO:0007528 3 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.053
regulation of cellular component biogenesis GO:0044087 281 0.053
negative regulation of protein metabolic process GO:0051248 391 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.051
metal ion transport GO:0030001 272 0.050
ubiquitin dependent protein catabolic process GO:0006511 206 0.047
negative regulation of catalytic activity GO:0043086 335 0.046
regulation of cell cycle GO:0051726 393 0.046
locomotory behavior GO:0007626 1 0.046
single organism cellular localization GO:1902580 332 0.045
Fly
positive regulation of catabolic process GO:0009896 310 0.045
positive regulation of nucleoside metabolic process GO:0045979 186 0.044
small gtpase mediated signal transduction GO:0007264 78 0.044
regulation of protein localization GO:0032880 296 0.041
Fly
endosomal transport GO:0016197 129 0.040
regulation of cellular response to stress GO:0080135 244 0.040
Fly
positive regulation of cellular component organization GO:0051130 376 0.039
regulation of nucleoside metabolic process GO:0009118 209 0.038
lipid biosynthetic process GO:0008610 177 0.038
negative regulation of protein phosphorylation GO:0001933 140 0.037
enzyme linked receptor protein signaling pathway GO:0007167 303 0.037
cation transport GO:0006812 331 0.037
positive regulation of hydrolase activity GO:0051345 331 0.037
positive regulation of gtpase activity GO:0043547 166 0.037
dephosphorylation GO:0016311 209 0.037
positive regulation of cell death GO:0010942 263 0.036
Fly
guanosine containing compound catabolic process GO:1901069 239 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.033
guanosine containing compound metabolic process GO:1901068 244 0.033
phospholipid metabolic process GO:0006644 99 0.033
negative regulation of cellular amine metabolic process GO:0033239 3 0.033
regulation of gtpase activity GO:0043087 180 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.032
gtp catabolic process GO:0006184 237 0.031
glycerolipid metabolic process GO:0046486 107 0.031
nucleotide catabolic process GO:0009166 408 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
signal transduction by phosphorylation GO:0023014 297 0.030
Fly
positive regulation of gtp catabolic process GO:0033126 166 0.030
determination of adult lifespan GO:0008340 2 0.030
chemical homeostasis GO:0048878 306 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.029
growth GO:0040007 202 0.029
regulation of response to external stimulus GO:0032101 222 0.028
regulation of protein kinase activity GO:0045859 289 0.028
positive regulation of nucleotide catabolic process GO:0030813 185 0.028
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
cellular macromolecule catabolic process GO:0044265 380 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
cytoplasmic transport GO:0016482 379 0.027
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
membrane organization GO:0061024 292 0.026
gtp metabolic process GO:0046039 239 0.026
protein processing GO:0016485 226 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
protein dephosphorylation GO:0006470 81 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
peptidyl serine phosphorylation GO:0018105 101 0.024
peptidyl serine modification GO:0018209 106 0.024
behavior GO:0007610 112 0.024
regulation of cell cycle process GO:0010564 266 0.024
mapk cascade GO:0000165 288 0.024
Fly
vesicle mediated transport GO:0016192 371 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
glycerophospholipid metabolic process GO:0006650 84 0.024
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.023
negative regulation of protein modification process GO:0031400 200 0.023
protein autophosphorylation GO:0046777 123 0.023
rho protein signal transduction GO:0007266 26 0.022
regulation of kinase activity GO:0043549 314 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
mitotic cell cycle GO:0000278 326 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
negative regulation of cell death GO:0060548 345 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
nuclear transport GO:0051169 179 0.021
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.021
histone modification GO:0016570 251 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.021
chromatin modification GO:0016568 298 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
regulation of intracellular transport GO:0032386 195 0.021
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.020
Fly
defense response GO:0006952 315 0.020
actin filament based process GO:0030029 224 0.020
regulation of cell motility GO:2000145 299 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
Fly
negative regulation of hydrolase activity GO:0051346 182 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
Fly
cellular component morphogenesis GO:0032989 314 0.019
negative regulation of kinase activity GO:0033673 106 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
system process GO:0003008 349 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
negative regulation of transferase activity GO:0051348 124 0.019
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.019
regulation of protein maturation GO:1903317 150 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
negative regulation of protein kinase activity GO:0006469 98 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
organophosphate catabolic process GO:0046434 430 0.018
post embryonic development GO:0009791 2 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
apoptotic signaling pathway GO:0097190 268 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
female gamete generation GO:0007292 2 0.018
modification dependent protein catabolic process GO:0019941 209 0.017
positive regulation of proteolysis GO:0045862 142 0.017
cell morphogenesis GO:0000902 296 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
Fly
actin cytoskeleton organization GO:0030036 207 0.017
regulation of transferase activity GO:0051338 355 0.017
mitotic cell cycle process GO:1903047 286 0.017
negative regulation of protein maturation GO:1903318 142 0.017
embryonic epithelial tube formation GO:0001838 4 0.016
negative regulation of proteolysis GO:0045861 132 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
protein localization to organelle GO:0033365 280 0.016
Fly
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
hindbrain development GO:0030902 3 0.016
regulation of mapk cascade GO:0043408 262 0.016
Fly
regulation of ras protein signal transduction GO:0046578 155 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
regulation of peptidase activity GO:0052547 180 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
Fly
anion transport GO:0006820 161 0.015
regulation of jnk cascade GO:0046328 73 0.015
Fly
transmembrane transport GO:0055085 399 0.015
regulation of defense response GO:0031347 154 0.015
regulation of growth GO:0040008 165 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
protein maturation GO:0051604 233 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
neural tube formation GO:0001841 3 0.014
response to radiation GO:0009314 151 0.014
blastocyst development GO:0001824 3 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
covalent chromatin modification GO:0016569 254 0.014
neurological system process GO:0050877 163 0.014
cation homeostasis GO:0055080 189 0.014
regulation of stress activated mapk cascade GO:0032872 84 0.014
Fly
regulation of proteolysis GO:0030162 293 0.014
Fly
purine containing compound catabolic process GO:0072523 411 0.014
protein acylation GO:0043543 138 0.014
oogenesis GO:0048477 2 0.014
receptor metabolic process GO:0043112 81 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
cation transmembrane transport GO:0098655 238 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
ion homeostasis GO:0050801 230 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
Fly
proteasomal protein catabolic process GO:0010498 176 0.013
multicellular organismal aging GO:0010259 3 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
positive regulation of ras gtpase activity GO:0032320 117 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
regulation of nucleocytoplasmic transport GO:0046822 98 0.013
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.013
membrane budding GO:0006900 28 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
lipid modification GO:0030258 84 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
Fly
maintenance of location GO:0051235 112 0.013
cellular homeostasis GO:0019725 196 0.013
embryo development GO:0009790 123 0.013
Fly
vesicle organization GO:0016050 62 0.013
protein catabolic process GO:0030163 325 0.013
cellular protein catabolic process GO:0044257 261 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
memory GO:0007613 3 0.012
immune effector process GO:0002252 159 0.012
regulation of protein complex assembly GO:0043254 147 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
protein targeting GO:0006605 187 0.012
Fly
synaptic vesicle recycling GO:0036465 3 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
sensory perception of smell GO:0007608 2 0.012
organ morphogenesis GO:0009887 147 0.012
Fly
response to other organism GO:0051707 261 0.012
regulation of protein stability GO:0031647 87 0.012
Fly
regulation of cellular component movement GO:0051270 334 0.012
protein localization to membrane GO:0072657 160 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
regulation of protein processing GO:0070613 150 0.012
positive regulation of secretion GO:0051047 116 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
carbohydrate metabolic process GO:0005975 207 0.012
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.011
protein import into nucleus GO:0006606 104 0.011
Fly
maintenance of cell polarity GO:0030011 2 0.011
organelle localization GO:0051640 84 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
immune system development GO:0002520 195 0.011
metal ion homeostasis GO:0055065 169 0.011
response to biotic stimulus GO:0009607 276 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
cofactor metabolic process GO:0051186 87 0.011
biological adhesion GO:0022610 331 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
response to light stimulus GO:0009416 87 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
single organism membrane organization GO:0044802 268 0.011
epithelium development GO:0060429 227 0.011
Fly
mitochondrion distribution GO:0048311 3 0.011
positive regulation of transport GO:0051050 336 0.011
small molecule biosynthetic process GO:0044283 157 0.011
lysosomal transport GO:0007041 33 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
autophagy GO:0006914 88 0.011
response to virus GO:0009615 126 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010
alcohol metabolic process GO:0006066 114 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
regulation of immune effector process GO:0002697 91 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
Fly
blastoderm segmentation GO:0007350 2 0.010
Fly
immune response GO:0006955 307 0.010
regulation of protein catabolic process GO:0042176 155 0.010

SPOPL disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.018
connective tissue disease DOID:65 109 0.018
disease of cellular proliferation DOID:14566 174 0.016
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.014