Homo sapiens

0 known processes

LRR1

leucine rich repeat protein 1

(Aliases: 4-1BBLRR,LRR-1,MGC20689,PPIL5)

LRR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 393 0.432
Worm
regulation of cell cycle process GO:0010564 266 0.331
Worm
modification dependent protein catabolic process GO:0019941 209 0.302
mitotic cell cycle process GO:1903047 286 0.288
Worm
cell cycle phase transition GO:0044770 173 0.229
Worm
cellular macromolecule catabolic process GO:0044265 380 0.222
ubiquitin dependent protein catabolic process GO:0006511 206 0.206
post embryonic development GO:0009791 2 0.190
Worm
negative regulation of mitotic cell cycle GO:0045930 102 0.186
Worm
mitotic cell cycle GO:0000278 326 0.155
Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.143
Worm
regulation of cell cycle phase transition GO:1901987 126 0.142
Worm
cell cycle checkpoint GO:0000075 117 0.138
Worm
mitotic cell cycle checkpoint GO:0007093 68 0.130
Worm
anterior posterior axis specification GO:0009948 2 0.125
regulation of mitotic cell cycle GO:0007346 189 0.121
Worm
negative regulation of cell cycle GO:0045786 193 0.116
Worm
segmentation GO:0035282 4 0.114
regulation of nuclear division GO:0051783 65 0.113
regulation of mitosis GO:0007088 63 0.106
regulation of kinase activity GO:0043549 314 0.102
mitotic sister chromatid separation GO:0051306 18 0.100
sister chromatid segregation GO:0000819 54 0.091
mitotic sister chromatid segregation GO:0000070 53 0.090
regulation of mitotic cell cycle phase transition GO:1901990 118 0.089
Worm
regulation of proteasomal protein catabolic process GO:0061136 87 0.085
regulation of meiotic cell cycle GO:0051445 4 0.079
microtubule based process GO:0007017 210 0.078
chromosome segregation GO:0007059 114 0.077
mitotic nuclear division GO:0007067 119 0.075
negative regulation of cell cycle process GO:0010948 121 0.075
Worm
cell division GO:0051301 168 0.074
cellular ketone metabolic process GO:0042180 80 0.072
positive regulation of cell cycle process GO:0090068 106 0.070
positive regulation of cell cycle GO:0045787 140 0.069
negative regulation of catalytic activity GO:0043086 335 0.069
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.068
anterior posterior axis specification embryo GO:0008595 2 0.067
negative regulation of protein metabolic process GO:0051248 391 0.066
blastoderm segmentation GO:0007350 2 0.066
regulation of protein catabolic process GO:0042176 155 0.066
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.063
cellular protein catabolic process GO:0044257 261 0.063
cellular amine metabolic process GO:0044106 41 0.063
protein catabolic process GO:0030163 325 0.063
positive regulation of meiotic cell cycle GO:0051446 2 0.055
meiotic chromosome segregation GO:0045132 4 0.051
negative regulation of cell cycle phase transition GO:1901988 89 0.051
Worm
organelle fission GO:0048285 149 0.049
regulation of mitotic sister chromatid segregation GO:0033047 27 0.049
posttranscriptional regulation of gene expression GO:0010608 213 0.048
vesicle mediated transport GO:0016192 371 0.047
nuclear division GO:0000280 128 0.047
regulation of transferase activity GO:0051338 355 0.047
regulation of mitotic sister chromatid separation GO:0010965 27 0.047
tripartite regional subdivision GO:0007351 2 0.046
multicellular organismal aging GO:0010259 3 0.044
protein modification by small protein conjugation GO:0032446 342 0.043
cellular response to dna damage stimulus GO:0006974 379 0.042
positive regulation of catabolic process GO:0009896 310 0.040
modification dependent macromolecule catabolic process GO:0043632 212 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.036
chromosome separation GO:0051304 23 0.036
regulation of chromosome organization GO:0033044 103 0.036
regulation of protein stability GO:0031647 87 0.036
cytokine production GO:0001816 247 0.036
rho protein signal transduction GO:0007266 26 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.035
proteasomal protein catabolic process GO:0010498 176 0.035
mapk cascade GO:0000165 288 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
regulation of sister chromatid segregation GO:0033045 27 0.035
regulation of chromosome segregation GO:0051983 44 0.033
cell morphogenesis involved in differentiation GO:0000904 144 0.033
mitotic cell cycle phase transition GO:0044772 162 0.033
Worm
secretion GO:0046903 254 0.033
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.033
cell projection organization GO:0030030 252 0.032
single organism cellular localization GO:1902580 332 0.032
positive regulation of cellular component organization GO:0051130 376 0.032
neuromuscular junction development GO:0007528 3 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
protein ubiquitination GO:0016567 314 0.031
dna integrity checkpoint GO:0031570 71 0.031
Worm
regulation of cell division GO:0051302 116 0.030
signal transduction by phosphorylation GO:0023014 297 0.030
small gtpase mediated signal transduction GO:0007264 78 0.030
regulation of cellular response to stress GO:0080135 244 0.029
positive regulation of phosphorylation GO:0042327 394 0.029
organelle localization GO:0051640 84 0.028
protein modification by small protein removal GO:0070646 92 0.028
cell projection morphogenesis GO:0048858 129 0.028
actin filament based process GO:0030029 224 0.028
peptidyl tyrosine modification GO:0018212 170 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.027
amine metabolic process GO:0009308 44 0.027
nervous system development GO:0007399 293 0.027
Fly
peptidyl tyrosine phosphorylation GO:0018108 170 0.027
regulation of cellular protein catabolic process GO:1903362 96 0.027
negative regulation of intracellular signal transduction GO:1902532 183 0.026
cellular macromolecular complex assembly GO:0034622 324 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cytoplasmic transport GO:0016482 379 0.024
cyclin catabolic process GO:0008054 6 0.023
cell part morphogenesis GO:0032990 137 0.023
mitotic dna damage checkpoint GO:0044773 28 0.023
protein targeting GO:0006605 187 0.022
intrinsic apoptotic signaling pathway GO:0097193 127 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.022
cell morphogenesis GO:0000902 296 0.021
cytokinesis GO:0000910 96 0.021
memory GO:0007613 3 0.021
response to steroid hormone GO:0048545 80 0.021
microtubule based movement GO:0007018 32 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
regulation of anatomical structure size GO:0090066 101 0.020
response to radiation GO:0009314 151 0.020
response to lipid GO:0033993 206 0.020
response to other organism GO:0051707 261 0.020
determination of adult lifespan GO:0008340 2 0.020
positive regulation of protein catabolic process GO:0045732 75 0.020
neurogenesis GO:0022008 169 0.020
Fly
regulation of proteolysis GO:0030162 293 0.019
regulation of protein maturation GO:1903317 150 0.019
dna damage checkpoint GO:0000077 68 0.019
regulation of protein kinase activity GO:0045859 289 0.019
protein monoubiquitination GO:0006513 39 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
positive regulation of organelle organization GO:0010638 195 0.019
neuron differentiation GO:0030182 138 0.019
negative regulation of cell death GO:0060548 345 0.019
positive regulation of proteolysis GO:0045862 142 0.019
establishment of chromosome localization GO:0051303 20 0.018
negative regulation of protein maturation GO:1903318 142 0.018
chemical homeostasis GO:0048878 306 0.018
response to bacterium GO:0009617 144 0.018
positive regulation of transferase activity GO:0051347 227 0.018
cullin deneddylation GO:0010388 9 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.018
negative regulation of programmed cell death GO:0043069 321 0.017
regulation of mapk cascade GO:0043408 262 0.017
response to abiotic stimulus GO:0009628 336 0.017
regulation of cytokine production GO:0001817 232 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.016
lipid biosynthetic process GO:0008610 177 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
protein processing GO:0016485 226 0.016
circulatory system development GO:0072359 262 0.016
actin cytoskeleton organization GO:0030036 207 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
peptidyl lysine modification GO:0018205 144 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
response to external biotic stimulus GO:0043207 261 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
methylation GO:0032259 106 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
regulation of cell differentiation GO:0045595 393 0.015
female gamete generation GO:0007292 2 0.015
reproductive process GO:0022414 106 0.015
protein secretion GO:0009306 98 0.015
protein homooligomerization GO:0051260 100 0.015
membrane organization GO:0061024 292 0.015
stem cell division GO:0017145 2 0.015
hemopoiesis GO:0030097 180 0.015
response to oxygen containing compound GO:1901700 369 0.015
establishment of organelle localization GO:0051656 59 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
negative regulation of protein processing GO:0010955 142 0.014
protein maturation GO:0051604 233 0.014
protein localization to organelle GO:0033365 280 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.014
secretion by cell GO:0032940 226 0.014
regulation of protein localization GO:0032880 296 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
immune system development GO:0002520 195 0.014
regulation of map kinase activity GO:0043405 108 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
intracellular protein transport GO:0006886 270 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
negative regulation of apoptotic process GO:0043066 316 0.013
metaphase anaphase transition of cell cycle GO:0044784 21 0.013
immune effector process GO:0002252 159 0.013
positive regulation of transport GO:0051050 336 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
cell adhesion GO:0007155 325 0.013
system process GO:0003008 349 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
chemotaxis GO:0006935 157 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
vasculature development GO:0001944 181 0.013
regulation of protein transport GO:0051223 213 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
taxis GO:0042330 157 0.012
response to biotic stimulus GO:0009607 276 0.012
generation of neurons GO:0048699 152 0.012
mitotic dna integrity checkpoint GO:0044774 30 0.012
Worm
cellular component morphogenesis GO:0032989 314 0.012
negative regulation of developmental process GO:0051093 247 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
adult locomotory behavior GO:0008344 1 0.012
positive regulation of immune system process GO:0002684 283 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
regionalization GO:0003002 29 0.012
negative regulation of organelle organization GO:0010639 126 0.012
reproduction GO:0000003 63 0.012
cardiovascular system development GO:0072358 262 0.012
biological adhesion GO:0022610 331 0.012
erbb signaling pathway GO:0038127 44 0.011
ion homeostasis GO:0050801 230 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
cellular chemical homeostasis GO:0055082 180 0.011
defense response GO:0006952 315 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.011
leukocyte activation GO:0045321 164 0.011
neuron projection development GO:0031175 106 0.011
positive regulation of kinase activity GO:0033674 204 0.011
organelle assembly GO:0070925 176 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
negative regulation of transport GO:0051051 176 0.011
small molecule biosynthetic process GO:0044283 157 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
protein polyubiquitination GO:0000209 110 0.011
protein stabilization GO:0050821 64 0.011
neuron development GO:0048666 113 0.011
nucleotide catabolic process GO:0009166 408 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
immune response GO:0006955 307 0.011
stress activated mapk cascade GO:0051403 93 0.011
positive regulation of cell cycle phase transition GO:1901989 22 0.011
chromosome localization GO:0050000 20 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
response to organic cyclic compound GO:0014070 204 0.010
cell type specific apoptotic process GO:0097285 125 0.010
stem cell development GO:0048864 69 0.010
chromatin organization GO:0006325 351 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010

LRR1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.012
immune system disease DOID:2914 155 0.011